Australasian Journal of Dermatology最新文献

{"title":"Biosimilars for Australian Dermatologists.","authors":"Grace X Li, Mona Marabani, Deshan F Sebaratnam","doi":"10.1111/ajd.14427","DOIUrl":"https://doi.org/10.1111/ajd.14427","url":null,"abstract":"<p><p>Biosimilars offer the potential for substantial cost savings within the Australian healthcare system. This is particularly salient in dermatology, where biologics are used to treat chronic skin diseases and cost savings will be accrued throughout the life of a patient. However, uptake of biosimilars in clinical practice has been hindered by barriers including insufficient clinician education, concerns about safety and efficacy, and negative patient perception. Increased availability of biosimilars promotes long-term sustainability of the Pharmaceutical Benefits Scheme and may help maintain equitable access to healthcare across Australia.</p>","PeriodicalId":8638,"journal":{"name":"Australasian Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143188119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Laryngeal Squamous Cell Carcinoma and Diathermy Plume.","authors":"Lachlan J Warren, Suren Krishnan","doi":"10.1111/ajd.14426","DOIUrl":"https://doi.org/10.1111/ajd.14426","url":null,"abstract":"<p><p>Plume from surgical diathermy systems is recognised as a hazard to healthcare providers but is often ignored during ambulatory care procedures. The development of a squamous cell carcinoma of the larynx in a dermatologist, despite the absence of recognised risk factors, prompted this review and recommendations for change in procedural practices.</p>","PeriodicalId":8638,"journal":{"name":"Australasian Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143078440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acneiform Eruption Secondary to Deucravacitinib: A Case Series and Review of the Literature.","authors":"Vanessa Tran, Celestine Wong, Senhong Lee, Michelle Rodrigues","doi":"10.1111/ajd.14425","DOIUrl":"https://doi.org/10.1111/ajd.14425","url":null,"abstract":"<p><p>Acneiform eruptions have been observed and reported in clinical trials for tyrosine kinase 2 (TYK2) inhibitors. However, data on their occurrence in real-world settings remain limited. This case series describes six patients, who developed acneiform eruptions following the initiation of deucravacitinib for chronic plaque psoriasis. Through this case series, we aim to shed further light into the clinical characteristics and potential risk factors for this side effect. Contrary to clinical trial data, we demonstrate high cessation rates of deucravacitinib following the development of acneiform eruption, due to the significant burden on quality of life. We highlight the need to identify risk factors to improve patient selection and allow adequate counselling or prophylactic treatments for these acneiform eruptions.</p>","PeriodicalId":8638,"journal":{"name":"Australasian Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143073559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"‘Psoriasis Punctata’: An Under-Recognised Clinical Phenotype of TNF-Alpha Inhibitor-Induced Psoriasis","authors":"Grace Im,&nbsp;Nidhi Kuchimanchi,&nbsp;Kira J. Dubester,&nbsp;Barrett J. Zlotoff,&nbsp;R. Hal Flowers","doi":"10.1111/ajd.14420","DOIUrl":"10.1111/ajd.14420","url":null,"abstract":"&lt;p&gt;Tumour necrosis factor (TNF)-alpha inhibitors are commonly used to treat numerous inflammatory conditions. Paradoxical psoriasiform eruptions (‘TNF inhibitor-induced psoriasis’) are well-recognised adverse effects and can manifest as plaque, guttate, inverse, pustular, scalp psoriasis, as well as psoriasiform eruptions [&lt;span&gt;1-3&lt;/span&gt;]. A small form of guttate psoriasis, termed here ‘psoriasis punctata’ has been seen routinely in our clinic. This morphology is underappreciated in literature. We aimed to characterise psoriasis punctata and compare its features with other subtypes of TNF-alpha-induced psoriasis.&lt;/p&gt;&lt;p&gt;Querying our institution's EMR system from 2004 to 2024, we identified 93 patients with TNF inhibitor-induced psoriasis. We collected data on demographics, the TNF inhibitor used, underlying inflammatory diseases, time to psoriasis onset after therapy initiation and lesion locations. Statistical analyses were performed using R, as shown in Table 1.&lt;/p&gt;&lt;p&gt;Among 93 patients with TNF inhibitor-induced psoriasis, 21 patients (22.6%) were diagnosed with psoriasis punctata after evaluation with clinical photographs and lesion descriptions (see Figure 1). The remaining 72 patients were categorised as the ‘other subtype’ group. Psoriasis punctata group had a younger average age at diagnosis (31.0 years) than the other subtypes (37.5 years). Sex proportions and the percentage of patients with pre-existing psoriasis were similar in both groups. Adalimumab and infliximab were most associated with psoriasis punctata (40.9% each), whereas adalimumab was most associated with other subtype psoriasis (56.9%). Average onset of psoriasis after starting TNF-alpha inhibitors was shorter in the psoriasis punctata group (19.0 months), than in the other subtype group (27.1 months), although this difference was statistically insignificant. Crohn's disease was the most common underlying condition in both groups (59.1% and 48.0%, respectively). Psoriasis distribution was similar in both groups, though psoriasis punctata lesions were more prevalent on the trunk and upper extremities, and less on the palms and soles (Figure 2). Notably, 66.7% of psoriasis punctata patients also presented with concurrent plaque psoriasis.&lt;/p&gt;&lt;p&gt;Psoriasis punctata lesions are often perifollicular and may show clinical and histologic overlap with pustular variants of psoriasis. Distinctive characteristics of psoriasis punctata include a scattered pinpoint rash that may present with an overlying scale. These lesions can occur on any part of the body and are typically smaller than those seen in guttate psoriasis. Previous literature has described various types of psoriasis [&lt;span&gt;4&lt;/span&gt;], with only one case report describing a patient with a ‘follicular psoriasiform eruption’ [&lt;span&gt;2&lt;/span&gt;]. Laga et al. [&lt;span&gt;5&lt;/span&gt;] examined 16 biopsies from nine patients with psoriasiform eruptions on TNF-α inhibitors, revealing psoriasiform patterns, lichenoid/interface patterns and ne","PeriodicalId":8638,"journal":{"name":"Australasian Journal of Dermatology","volume":"66 1","pages":"42-44"},"PeriodicalIF":2.2,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ajd.14420","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143062878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ichthyosis Prematurity Syndrome","authors":"Grace X. Li,&nbsp;Kathryn Chen,&nbsp;Deshan F. Sebaratnam,&nbsp;James P. Pham","doi":"10.1111/ajd.14419","DOIUrl":"10.1111/ajd.14419","url":null,"abstract":"&lt;p&gt;Ichthyosis prematurity syndrome (IPS) is a rare autosomal recessive congenital disorder characterised by premature birth, congenital ichthyosis and neonatal respiratory distress. IPS is caused by pathogenic variants of the &lt;i&gt;SLC27A4&lt;/i&gt; gene encoding fatty acid transporter protein 4 (FATP4), resulting in skin barrier dysfunction [&lt;span&gt;1&lt;/span&gt;]. Herein, we present, to our knowledge, the first Australian case of IPS in a patient of Indonesian heritage.&lt;/p&gt;&lt;p&gt;A male infant of Indonesian heritage was born at 29 + 3 weeks gestation with diffuse scaling. He was born to healthy non-consanguineous parents, with his mother gravida 1, parity 1. Routine antenatal screening was unremarkable, but polyhydramnios was identified 1 day prior to delivery. Labour was induced following prolonged rupture of membranes with suspected chorioamnionitis, and he was ultimately born via Caesarean section due to breech positioning and foetal distress.&lt;/p&gt;&lt;p&gt;His birthweight was 1882 g, and his APGAR scores at 1, 5 and 10 minutes were 1, 6 and 6, respectively. Widespread clay-like vernix was noted affecting the scalp, face, back and upper and lower extremities (Figure 1), with occlusion of the auditory canals. Soon after birth, he developed respiratory distress, with chest X-ray showing ill-defined multilobar opacities compatible with pulmonary oedema (Figure 2). He had transient eosinophilia of 12% (normal: &lt; 5%). Serum immunoglobulin E (IgE) was not tested. No abnormal findings were reported on abdominal X-ray, renal ultrasound and cranial ultrasound. Histology of the exfoliated scale demonstrated anucleate keratin.&lt;/p&gt;&lt;p&gt;He was transferred to the neonatal intensive care unit, placed on continuous positive airway pressure (CPAP) ventilation and administered surfactant. CPAP was transitioned to low-flow oxygen on day 19 postnatally. Other postnatal complications included jaundice, &lt;i&gt;Staphylococcus aureus&lt;/i&gt;-associated conjunctivitis and anaemia of prematurity. Breastfeeding was supplemented by enteral nutrition.&lt;/p&gt;&lt;p&gt;The patient was discharged after 10 weeks (corrected age 39 + 4 weeks gestation), with a continuing requirement for low-flow oxygen until 5 months of age. Newborn hearing screen test results were abnormal but normalised at 4 months. His skin was managed with white soft paraffin, with spontaneous shedding of scale. At 8 months, there was complete resolution of ichthyosis (Figure 2), and development was within normal limits.&lt;/p&gt;&lt;p&gt;Genetic testing confirmed the presence of germline, compound heterozygous variants of the &lt;i&gt;SLC27A4&lt;/i&gt; gene. The first was a pathogenic deletion of exons 8 to 10, previously implicated in IPS [&lt;span&gt;2, 3&lt;/span&gt;]. The second was a single nucleotide change at c.986C&gt;T (p.Thr329Met) of uncertain significance, which has been previously reported in the literature as a homozygous variant in patients with clinical IPS [&lt;span&gt;4&lt;/span&gt;].&lt;/p&gt;&lt;p&gt;While respiratory distress may also be seen in collodion and Harlequin presentations, in","PeriodicalId":8638,"journal":{"name":"Australasian Journal of Dermatology","volume":"66 2","pages":"107-109"},"PeriodicalIF":2.2,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ajd.14419","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143045471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Wolf's Isotopic Response: Acquired Arteriovenous Haemangioma Following Oral Herpes Simplex Virus Infection","authors":"Vanessa Tran,&nbsp;Vanessa Morgan,&nbsp;Laura Scardamaglia","doi":"10.1111/ajd.14421","DOIUrl":"10.1111/ajd.14421","url":null,"abstract":"<div>\u0000 \u0000 <p>Cutaneous arteriovenous haemangioma (AVH) is a rare benign vascular lesion, which typically occurs on the head and neck. Its aetiology is unclear but thrombosis, trauma, infection or endocrine triggers have been proposed. We report the case of a 64-year-old female presenting with acquired AVH of the upper lip following oral herpes simplex virus infection. This is the first documented occurrence of AVH as a post-herpetic isotopic response (PHIR).</p>\u0000 </div>","PeriodicalId":8638,"journal":{"name":"Australasian Journal of Dermatology","volume":"66 2","pages":"e46-e48"},"PeriodicalIF":2.2,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143045474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Features and Risks of Congenital Melanocytic Naevi: A Retrospective Analysis of Patients at the Queensland Children's Hospital","authors":"Yolanka Lobo,&nbsp;Jessica Zhuang,&nbsp;Hannah Gribbin,&nbsp;William Felipe Pinzon Perez,&nbsp;H. Peter Soyer,&nbsp;Laura Wheller","doi":"10.1111/ajd.14418","DOIUrl":"10.1111/ajd.14418","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background/Objectives</h3>\u0000 \u0000 <p>Congenital melanocytic naevi (CMN) are a risk factor for melanoma. Melanoma risk is dependent on the congenital phenotype. Our primary aims were to assess the clinical characteristics of CMN that indicate a high risk of neurocutaneous melanosis (NCM) and melanoma in an Australian paediatric population group; to identify patient characteristics and clinical features of CMN that trigger further investigations; and to determine the rate of malignancy and other complications for CMN.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We retrospectively reviewed the electronic medical records of all patients under 18 years who were diagnosed with CMN at the Queensland Children's Hospital between 2014 and 2021.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Eighty-eight patients (38 males and 50 females) were included in the analysis. Eighteen patients (20%) had a biopsy to rule out malignancy. Central nervous system magnetic resonance imaging (MRI) was performed in 16 patients (18%). Five patients (5.7%) experienced complications, of which three had NCM and two had transient neurological symptoms with normal MRI. No cases of melanoma, non-melanoma tumours or deaths were recorded.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>CMN size, location over the posterior midline axis and multiple numbers of CMN were found to be significantly associated with the development of complications. CMN size, CMN site, presence of satellite naevi and location over the posterior midline axis were all significantly associated with the likelihood of an MRI or biopsy being performed. Large-scale studies, such as a population-based registry, are recommended to accurately assess the true lifetime risk of complications and associated risk factors.</p>\u0000 </section>\u0000 </div>","PeriodicalId":8638,"journal":{"name":"Australasian Journal of Dermatology","volume":"66 2","pages":"61-68"},"PeriodicalIF":2.2,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ajd.14418","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142999200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcomes of a fledgling public dermatology clinic in rural Australia","authors":"Grace Xiaoying Li BSc (Med) Hons,&nbsp;Xin Lin Wong BMed, MD MMed (Clin Epi),&nbsp;Deshan Frank Sebaratnam MBBS (Hons), MMed (Clin Epi), FRCP (London), FACD","doi":"10.1111/ajd.14399","DOIUrl":"10.1111/ajd.14399","url":null,"abstract":"<p>There is paucity of research available regarding the epidemiological characteristics of patients attending dermatology outpatient services in rural Australia. We performed a retrospective cohort study of patients attending a public dermatology clinic established at Dubbo Base Hospital in rural New South Wales. The broad range of dermatological presentations encountered, coupled with the brisk uptake of services by remote patients, highlights the ongoing need for specialist dermatology services in underserved rural communities.</p>","PeriodicalId":8638,"journal":{"name":"Australasian Journal of Dermatology","volume":"66 2","pages":"93-96"},"PeriodicalIF":2.2,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ajd.14399","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142999203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recurrent Erysipelas: An Important Buttock Dermatosis, in Hindsight","authors":"Serene Chan,&nbsp;Lachlan Byth","doi":"10.1111/ajd.14414","DOIUrl":"10.1111/ajd.14414","url":null,"abstract":"&lt;p&gt;Erysipelas is a superficial bacterial infection of the dermis, typically caused by beta-haemolytic streptococci including &lt;i&gt;Streptococcus pyogenes&lt;/i&gt; (group A), &lt;i&gt;S. agalactiae&lt;/i&gt; (group B) and &lt;i&gt;S. dysgalactiae&lt;/i&gt; (group C/G). The typical site is the lower leg, with the face, arm or surgical wounds affected in a minority of cases. Gluteal erysipelas is uncommon and can be multiply recurrent [&lt;span&gt;1&lt;/span&gt;].&lt;/p&gt;&lt;p&gt;An 89-year-old woman presented to hospital with an acute painful eruption on the buttocks which began 48 h prior. The patient had experienced five similar episodes in the same distribution over the past 12 months, each of which had resolved with oral clindamycin over 1–2 weeks. The past medical history included recurrent urinary tract infections and stress incontinence. There was no history of trauma or immobility.&lt;/p&gt;&lt;p&gt;Examination revealed well-demarcated, warm, indurated, blanchable plaques on the bilateral buttocks, with an irregular border and peripheral papules. Superficial linear erosions were present on the medial buttocks (Figure 1). The patient was afebrile and there was no inguinal lymphadenopathy. The differential diagnosis included erysipelas, giant cellulitis-like Sweet syndrome, leukaemia cutis, Wells syndrome, panniculitis (including cold panniculitis, factitial panniculitis or paraffinoma), interstitial granulomatous dermatitis, urticaria and irritant contact dermatitis.&lt;/p&gt;&lt;p&gt;Skin biopsy showed papillary dermal oedema and a mixed perivascular and interstitial inflammatory infiltrate, including neutrophils undergoing karyorrhexis (Figure 2). The white cell count was 5.2 × 10&lt;sup&gt;9&lt;/sup&gt;/L (4.0–10.0), CRP 119 mg/L (&lt; 5) and blood cultures negative. Swabs from the erosion showed growth of group C/G streptococcus, sensitive to penicillin. The eruption resolved with intravenous cefazolin followed by oral cefalexin for a total of 14 days. Prophylactic penicillin V 500 mg twice daily was commenced at follow-up, and the patient was referred for consideration of low-dose topical oestrogen for genitourinary syndrome of menopause.&lt;/p&gt;&lt;p&gt;Gluteal erysipelas accounts for fewer than 1% of cases of erysipelas. Besides streptococci, &lt;i&gt;Staphylococcus aureus&lt;/i&gt; and Gram-negative bacteria are occasionally responsible. The classical presentation is a circumscribed, fiery-red plaque in a butterfly-like distribution over the buttocks. Lesions pass through violaceous and bruise-like stages as they resolve with antibiotic therapy. Predisposing factors are divided into local (lymphoedema, immobility, trauma, surgery, vaginal or anorectal streptococcal colonisation) and systemic (immunosuppression, obesity, metabolic syndrome, alcohol use disorder) [&lt;span&gt;2-4&lt;/span&gt;]. Group B and C/G streptococci have a predilection for the buttocks, with most cases occurring in females, and vaginal colonisation may be the common factor [&lt;span&gt;2&lt;/span&gt;]. Multiple recurrences occur in one-third of patients, with cumulative lymphatic injury, impaire","PeriodicalId":8638,"journal":{"name":"Australasian Journal of Dermatology","volume":"66 2","pages":"e65-e66"},"PeriodicalIF":2.2,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ajd.14414","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142982518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating Lichen Sclerosus in Phimosis: Insights From a Multidisciplinary Retrospective Study","authors":"Stefano Bighetti,&nbsp;Stefano Mancon,&nbsp;Nazareno Suardi,&nbsp;Piergiacomo Calzavara-Pinton,&nbsp;Vincenzo Maione,&nbsp;Mariachiara Arisi,&nbsp;Giovanni Lughezzani,&nbsp;Nicola Zerbinati,&nbsp;Iacopo Ghini,&nbsp;Luca Bettolini","doi":"10.1111/ajd.14417","DOIUrl":"10.1111/ajd.14417","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>This study aimed to evaluate the prevalence of lichen sclerosus (LS) in male patients undergoing circumcision for phimosis, emphasising the significance of a multidisciplinary approach in the early diagnosis and management of this condition.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A retrospective analysis was performed on 841 male patients who underwent circumcision at a high-volume medical centre between 2001 and 2023. Data were collected on clinical diagnoses made by both dermatologists and urologists, along with the corresponding histological findings. Logistic regression models were utilised to assess diagnostic accuracy and the relationship between clinical suspicion and histological confirmation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Histological confirmation of LS was identified in 30.6% of the cases. Dermatologists demonstrated a diagnostic accuracy of 81.8%, whereas urologists showed an accuracy of 46.1%. The evaluations conducted by dermatologists exhibited a significant correlation with histological confirmation of LS (odds ratio 4.81; 95% confidence interval: 1.96–11.80; <i>p</i> = 0.001).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>This study elucidates the differences in diagnostic accuracy between dermatologists and urologists in identifying LS in patients undergoing circumcision for phimosis, highlighting the necessity of a multidisciplinary approach to improve the diagnostic process. Furthermore, the epidemiological data obtained from this research offer valuable insights into the prevalence of LS and the associated diagnostic challenges within a substantial patient cohort.</p>\u0000 </section>\u0000 </div>","PeriodicalId":8638,"journal":{"name":"Australasian Journal of Dermatology","volume":"66 2","pages":"e39-e42"},"PeriodicalIF":2.2,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ajd.14417","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142982516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}