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Clinical staging to guide actionable management of systemic metabolic disorders and their sequelae: A European atherosclerosis society consensus statement 临床分期指导系统性代谢紊乱及其后遗症的可操作管理：欧洲动脉粥样硬化学会共识声明
IF 4.9 2区 医学
Atherosclerosis Pub Date : 2025-07-18 DOI: 10.1016/j.atherosclerosis.2025.120377
Stefano Romeo
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引用次数: 0
Unraveling the vascular threat: Elevated risk and poor prognosis of aortic aneurysms and dissections in polycystic kidney disease 揭示血管威胁：多囊肾病中主动脉瘤和夹层的风险升高和预后不良
IF 4.9 2区 医学
Atherosclerosis Pub Date : 2025-07-18 DOI: 10.1016/j.atherosclerosis.2025.120323
Pao-Hsien Chu, Kuang-Tso Lee
{"title":"Unraveling the vascular threat: Elevated risk and poor prognosis of aortic aneurysms and dissections in polycystic kidney disease","authors":"Pao-Hsien Chu, Kuang-Tso Lee","doi":"10.1016/j.atherosclerosis.2025.120323","DOIUrl":"10.1016/j.atherosclerosis.2025.120323","url":null,"abstract":"","PeriodicalId":8623,"journal":{"name":"Atherosclerosis","volume":"407 ","pages":"Article 120323"},"PeriodicalIF":4.9,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144663631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Non-canonical WNT signalling promotes vascular smooth muscle cell calcification via complement 3 非规范WNT信号通过补体3促进血管平滑肌细胞钙化
IF 4.9 2区 医学
Atherosclerosis Pub Date : 2025-07-18 DOI: 10.1016/j.atherosclerosis.2025.120367
Ileana Badi , Ioannis Akoumianakis , Sibel Kurt , Matthew Williams , Alejandro Cardona-Monzonís , Georgina Miles , Marianne Riering , Jagat S. Chauhan , Murray Polkinghorne , Christos P. Kotanidis , Daniel Foran , Rana Sayeed , George Krasopoulos , Vivek Srivastava , Nicholas Walcot , Antonios Kourliouros , Priya Sastry , Keith Channon , Charalambos Antoniades
{"title":"Non-canonical WNT signalling promotes vascular smooth muscle cell calcification via complement 3","authors":"Ileana Badi , Ioannis Akoumianakis , Sibel Kurt , Matthew Williams , Alejandro Cardona-Monzonís , Georgina Miles , Marianne Riering , Jagat S. Chauhan , Murray Polkinghorne , Christos P. Kotanidis , Daniel Foran , Rana Sayeed , George Krasopoulos , Vivek Srivastava , Nicholas Walcot , Antonios Kourliouros , Priya Sastry , Keith Channon , Charalambos Antoniades","doi":"10.1016/j.atherosclerosis.2025.120367","DOIUrl":"10.1016/j.atherosclerosis.2025.120367","url":null,"abstract":"","PeriodicalId":8623,"journal":{"name":"Atherosclerosis","volume":"407 ","pages":"Article 120367"},"PeriodicalIF":4.9,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144661960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nonclinical data demonstrate potent and precise inactivation of liver PCSK9 in vivo with the clinical stage GalNAc base editing medicine, VERVE-102 非临床数据显示，临床阶段GalNAc碱基编辑药物VERVE-102在体内有效且精确地灭活肝脏PCSK9
IF 4.9 2区 医学
Atherosclerosis Pub Date : 2025-07-18 DOI: 10.1016/j.atherosclerosis.2025.120333
Ellen Rohde, Richard Lee, Anne Marie Mazzola, Colin Platt, Taiji Mizoguchi, Kim Pendino, Alexandra Chadwick, Amit Khera, Scott Vafai, Sekar Kathiresan, Troy Lister, Joseph Biedenkapp
{"title":"Nonclinical data demonstrate potent and precise inactivation of liver PCSK9 in vivo with the clinical stage GalNAc base editing medicine, VERVE-102","authors":"Ellen Rohde, Richard Lee, Anne Marie Mazzola, Colin Platt, Taiji Mizoguchi, Kim Pendino, Alexandra Chadwick, Amit Khera, Scott Vafai, Sekar Kathiresan, Troy Lister, Joseph Biedenkapp","doi":"10.1016/j.atherosclerosis.2025.120333","DOIUrl":"10.1016/j.atherosclerosis.2025.120333","url":null,"abstract":"","PeriodicalId":8623,"journal":{"name":"Atherosclerosis","volume":"407 ","pages":"Article 120333"},"PeriodicalIF":4.9,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144662019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endothelial micronuclei signatures and CGAS activation: Key determinants of atherosclerosis 内皮微核特征和CGAS激活：动脉粥样硬化的关键决定因素
IF 4.9 2区 医学
Atherosclerosis Pub Date : 2025-07-18 DOI: 10.1016/j.atherosclerosis.2025.120371
Lucia Natarelli , Zahra Abedi Kichi , Luca Parca , Sarajo Mohanta , Remco Megens , George Shakir , Yvonne Jansen , Tommaso Mazza , Christian Weber
{"title":"Endothelial micronuclei signatures and CGAS activation: Key determinants of atherosclerosis","authors":"Lucia Natarelli , Zahra Abedi Kichi , Luca Parca , Sarajo Mohanta , Remco Megens , George Shakir , Yvonne Jansen , Tommaso Mazza , Christian Weber","doi":"10.1016/j.atherosclerosis.2025.120371","DOIUrl":"10.1016/j.atherosclerosis.2025.120371","url":null,"abstract":"","PeriodicalId":8623,"journal":{"name":"Atherosclerosis","volume":"407 ","pages":"Article 120371"},"PeriodicalIF":4.9,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144662033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Current guidelines result in extensive pregnancy-related off-treatment time in women with familial hypercholesterolemia 目前的指南导致家族性高胆固醇血症妇女妊娠相关停药时间过长
IF 4.9 2区 医学
Atherosclerosis Pub Date : 2025-07-18 DOI: 10.1016/j.atherosclerosis.2025.120314
Marianne Klevmoen , Jeanine Roeters Van Lennep , Martin Bogsrud , Elisabeth Vesterbekkmo , Eva Pedersen , Kjetil Retterstøl , Kirsten Holven
{"title":"Current guidelines result in extensive pregnancy-related off-treatment time in women with familial hypercholesterolemia","authors":"Marianne Klevmoen , Jeanine Roeters Van Lennep , Martin Bogsrud , Elisabeth Vesterbekkmo , Eva Pedersen , Kjetil Retterstøl , Kirsten Holven","doi":"10.1016/j.atherosclerosis.2025.120314","DOIUrl":"10.1016/j.atherosclerosis.2025.120314","url":null,"abstract":"","PeriodicalId":8623,"journal":{"name":"Atherosclerosis","volume":"407 ","pages":"Article 120314"},"PeriodicalIF":4.9,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144662183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mitochondria as novel modulators of LDLR plasmamembrane availability: The role of carmaboyl phosphate synthetase 1 线粒体作为LDLR质膜可用性的新调节剂：磷酸马糖酰合成酶的作用
IF 4.9 2区 医学
Atherosclerosis Pub Date : 2025-07-18 DOI: 10.1016/j.atherosclerosis.2025.120350
Maria Giovanna Lupo , Cinzia Franchin , Ilaria Rossi , Giorgia Marodin , Lorenzo Da Dalt , Giorgio Arrigoni , Danilo Norata , Nicola Ferri
{"title":"Mitochondria as novel modulators of LDLR plasmamembrane availability: The role of carmaboyl phosphate synthetase 1","authors":"Maria Giovanna Lupo , Cinzia Franchin , Ilaria Rossi , Giorgia Marodin , Lorenzo Da Dalt , Giorgio Arrigoni , Danilo Norata , Nicola Ferri","doi":"10.1016/j.atherosclerosis.2025.120350","DOIUrl":"10.1016/j.atherosclerosis.2025.120350","url":null,"abstract":"","PeriodicalId":8623,"journal":{"name":"Atherosclerosis","volume":"407 ","pages":"Article 120350"},"PeriodicalIF":4.9,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144662450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transient expression of Reg3Β by smooth muscle cells affects atherosclerosis in mice 平滑肌细胞短暂表达Reg3Β影响小鼠动脉粥样硬化
IF 4.9 2区 医学
Atherosclerosis Pub Date : 2025-07-18 DOI: 10.1016/j.atherosclerosis.2025.120341
Laia Cañes Esteve, Holger Lörchner, Maria Goes, Jochen Pöling
{"title":"Transient expression of Reg3Β by smooth muscle cells affects atherosclerosis in mice","authors":"Laia Cañes Esteve, Holger Lörchner, Maria Goes, Jochen Pöling","doi":"10.1016/j.atherosclerosis.2025.120341","DOIUrl":"10.1016/j.atherosclerosis.2025.120341","url":null,"abstract":"","PeriodicalId":8623,"journal":{"name":"Atherosclerosis","volume":"407 ","pages":"Article 120341"},"PeriodicalIF":4.9,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144662460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Detection of multicellular transcriptional programs and immune cell phenotypes that predict outcomes of patients with coronary artery disease 检测多细胞转录程序和免疫细胞表型预测冠心病患者的预后
IF 4.9 2区 医学
Atherosclerosis Pub Date : 2025-07-18 DOI: 10.1016/j.atherosclerosis.2025.120369
Hauke Horstmann , Nathaly Anto Michel , Winfried März , Andreas Zirlik , Dennis Wolf , Timoteo Marchini
{"title":"Detection of multicellular transcriptional programs and immune cell phenotypes that predict outcomes of patients with coronary artery disease","authors":"Hauke Horstmann , Nathaly Anto Michel , Winfried März , Andreas Zirlik , Dennis Wolf , Timoteo Marchini","doi":"10.1016/j.atherosclerosis.2025.120369","DOIUrl":"10.1016/j.atherosclerosis.2025.120369","url":null,"abstract":"","PeriodicalId":8623,"journal":{"name":"Atherosclerosis","volume":"407 ","pages":"Article 120369"},"PeriodicalIF":4.9,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144662644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Loss-of-function in endothelial lipase increases LDL cholesterol but decreases risk of atherosclerotic cardiovascular disease 内皮脂肪酶功能丧失增加LDL胆固醇，但降低动脉粥样硬化性心血管疾病的风险
IF 4.9 2区 医学
Atherosclerosis Pub Date : 2025-07-18 DOI: 10.1016/j.atherosclerosis.2025.119486
Benjamin Wadström, Anders Wulff, Borge Nordestgaard
{"title":"Loss-of-function in endothelial lipase increases LDL cholesterol but decreases risk of atherosclerotic cardiovascular disease","authors":"Benjamin Wadström, Anders Wulff, Borge Nordestgaard","doi":"10.1016/j.atherosclerosis.2025.119486","DOIUrl":"10.1016/j.atherosclerosis.2025.119486","url":null,"abstract":"","PeriodicalId":8623,"journal":{"name":"Atherosclerosis","volume":"407 ","pages":"Article 119486"},"PeriodicalIF":4.9,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144662967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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