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PHASE 1 EVALUATION OF PHARMACOKINETIC DRUG-DRUG INTERACTIONS BETWEEN ENLICITIDE AND MULTIPLE CONCOMITANT MEDICATIONS 依利昔肽与多种伴随药物之间药代动力学相互作用的一期评价
IF 7.1 2区 医学
Atherosclerosis Pub Date : 2026-08-01 Epub Date: 2026-09-09 DOI: 10.1016/j.atherosclerosis.2026.120851
Douglas Johns, Jeanette Alicea, Patrice Auger, Ednan Bajwa, Puja Banka, Piyali Basak, David Bruce, Josee Cote, Kiet Giang, Jing Jin, Helen Manthos, Rahul Mishra, Shruti Patel, Max Pistilli, Jonathan Pollock, Michelle Valentine, Dennis Wolford, Islam Younis, Susan Zhou
{"title":"PHASE 1 EVALUATION OF PHARMACOKINETIC DRUG-DRUG INTERACTIONS BETWEEN ENLICITIDE AND MULTIPLE CONCOMITANT MEDICATIONS","authors":"Douglas Johns, Jeanette Alicea, Patrice Auger, Ednan Bajwa, Puja Banka, Piyali Basak, David Bruce, Josee Cote, Kiet Giang, Jing Jin, Helen Manthos, Rahul Mishra, Shruti Patel, Max Pistilli, Jonathan Pollock, Michelle Valentine, Dennis Wolford, Islam Younis, Susan Zhou","doi":"10.1016/j.atherosclerosis.2026.120851","DOIUrl":"10.1016/j.atherosclerosis.2026.120851","url":null,"abstract":"","PeriodicalId":8623,"journal":{"name":"Atherosclerosis","volume":"419 ","pages":"Article 120851"},"PeriodicalIF":7.1,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148915859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
THE ARYL HYDROCARBON RECEPTOR (AHR) IS A NOVEL REGULATOR OF LIPID METABOLISM AND ATHEROSCLEROSIS DEVELOPMENT. 芳烃受体（ahr）是一种新的脂质代谢和动脉粥样硬化发展的调节剂。
IF 7.1 2区 医学
Atherosclerosis Pub Date : 2026-08-01 Epub Date: 2026-09-09 DOI: 10.1016/j.atherosclerosis.2026.120918
Rosanna Huchzermeier, Renske De Jong, Han Jin, Vasiliki Triantafyllidou, Donato Santovito, Erik Biessen, Caspar Ohnmacht, Emiel Van Der Vorst
{"title":"THE ARYL HYDROCARBON RECEPTOR (AHR) IS A NOVEL REGULATOR OF LIPID METABOLISM AND ATHEROSCLEROSIS DEVELOPMENT.","authors":"Rosanna Huchzermeier, Renske De Jong, Han Jin, Vasiliki Triantafyllidou, Donato Santovito, Erik Biessen, Caspar Ohnmacht, Emiel Van Der Vorst","doi":"10.1016/j.atherosclerosis.2026.120918","DOIUrl":"10.1016/j.atherosclerosis.2026.120918","url":null,"abstract":"","PeriodicalId":8623,"journal":{"name":"Atherosclerosis","volume":"419 ","pages":"Article 120918"},"PeriodicalIF":7.1,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148916672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
TARGETING ENDOTHELIAL ADHESION MOLECULES WITH SAFFRON BIOACTIVE COMPOUNDS: IN SILICO AND AORTIC TISSUE ANALYSIS IN ATHEROSCLEROTIC ANIMAL MODEL 靶向内皮粘附分子的藏红花生物活性化合物：在动脉粥样硬化动物模型中的硅和主动脉组织分析
IF 7.1 2区 医学
Atherosclerosis Pub Date : 2026-08-01 Epub Date: 2026-09-09 DOI: 10.1016/j.atherosclerosis.2026.120930
Hazirah Watikah Abdah, Noorul Izzati Hanafi, Suhaila Abd Muid, Effat Omar, Siti Azma Jusoh, Nor Hidayatul Khamariah Zainul Abidin, Noor Alicezah Mohd Kasim
{"title":"TARGETING ENDOTHELIAL ADHESION MOLECULES WITH SAFFRON BIOACTIVE COMPOUNDS: IN SILICO AND AORTIC TISSUE ANALYSIS IN ATHEROSCLEROTIC ANIMAL MODEL","authors":"Hazirah Watikah Abdah, Noorul Izzati Hanafi, Suhaila Abd Muid, Effat Omar, Siti Azma Jusoh, Nor Hidayatul Khamariah Zainul Abidin, Noor Alicezah Mohd Kasim","doi":"10.1016/j.atherosclerosis.2026.120930","DOIUrl":"10.1016/j.atherosclerosis.2026.120930","url":null,"abstract":"","PeriodicalId":8623,"journal":{"name":"Atherosclerosis","volume":"419 ","pages":"Article 120930"},"PeriodicalIF":7.1,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148916692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
LIPOPROTEIN(A) UNDERGOES ENDOTHELIAL TRANSCYTOSIS VIA ACTIVIN RECEPTOR-LIKE KINASE 1: A NOVEL MECHANISM FOR RESIDUAL CARDIOVASCULAR RISK 脂蛋白(a)通过激活素受体样激酶1经历内皮胞吞作用：残留心血管风险的新机制
IF 7.1 2区 医学
Atherosclerosis Pub Date : 2026-08-01 Epub Date: 2026-09-09 DOI: 10.1016/j.atherosclerosis.2026.120843
Andria Henry, Ruoqi Wang, Yitong Liu, Ho Man Ryan Yee, Sarah Fidora, Michael Boffa, Marlys Koschinsky, Changsen Wang, Warren Lee
{"title":"LIPOPROTEIN(A) UNDERGOES ENDOTHELIAL TRANSCYTOSIS VIA ACTIVIN RECEPTOR-LIKE KINASE 1: A NOVEL MECHANISM FOR RESIDUAL CARDIOVASCULAR RISK","authors":"Andria Henry, Ruoqi Wang, Yitong Liu, Ho Man Ryan Yee, Sarah Fidora, Michael Boffa, Marlys Koschinsky, Changsen Wang, Warren Lee","doi":"10.1016/j.atherosclerosis.2026.120843","DOIUrl":"10.1016/j.atherosclerosis.2026.120843","url":null,"abstract":"","PeriodicalId":8623,"journal":{"name":"Atherosclerosis","volume":"419 ","pages":"Article 120843"},"PeriodicalIF":7.1,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148924395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
EPIGENETIC PCSK9 SILENCING WITH STX-1150 PROVIDES DURABLE LDL-C CONTROL AFTER A SINGLE DOSE stx-1150的表观遗传pcsk9沉默在单剂量后提供持久的ldl-c控制
IF 7.1 2区 医学
Atherosclerosis Pub Date : 2026-08-01 Epub Date: 2026-09-09 DOI: 10.1016/j.atherosclerosis.2026.120860
Emeric Charles, Steven Keller, Shyam Bale, Jason Fernandes, Carlos Santamaria, Heather Kozy, Maitreyee Karmarkar, Yuexuan Li, Oleh Krupa, Simon Bucher, Keith Schulwach, Sterling Ripley-Phipps, Natalie Goh, Fred Deiter, Michelle Eggers, Christie Sze, Farah Bardai, Sarah Denny, Benjamin Oakes
{"title":"EPIGENETIC PCSK9 SILENCING WITH STX-1150 PROVIDES DURABLE LDL-C CONTROL AFTER A SINGLE DOSE","authors":"Emeric Charles, Steven Keller, Shyam Bale, Jason Fernandes, Carlos Santamaria, Heather Kozy, Maitreyee Karmarkar, Yuexuan Li, Oleh Krupa, Simon Bucher, Keith Schulwach, Sterling Ripley-Phipps, Natalie Goh, Fred Deiter, Michelle Eggers, Christie Sze, Farah Bardai, Sarah Denny, Benjamin Oakes","doi":"10.1016/j.atherosclerosis.2026.120860","DOIUrl":"10.1016/j.atherosclerosis.2026.120860","url":null,"abstract":"","PeriodicalId":8623,"journal":{"name":"Atherosclerosis","volume":"419 ","pages":"Article 120860"},"PeriodicalIF":7.1,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148924403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PLASMA METABOLOMICS PROFILE OF ALCOHOL CONSUMPTION AND ASSOCIATION WITH CARDIOVASCULAR DISEASE: A MULTI-COHORT STUDY FROM SWEDEN 血浆代谢组学分析饮酒与心血管疾病的关系：来自瑞典的一项多队列研究
IF 7.1 2区 医学
Atherosclerosis Pub Date : 2026-08-01 Epub Date: 2026-09-09 DOI: 10.1016/j.atherosclerosis.2026.120894
Luka Marko Rašo, Ulf Hammar, Koen Dekkers, Susanna Larsson, Karl Michaëlsson, Marju Orho-Melander, Rikard Landberg, Gunnar Engström, J. Gustav Smith, Johan Ärnlöv, Lars Lind, Tove Fall, Shafqat Ahmad
{"title":"PLASMA METABOLOMICS PROFILE OF ALCOHOL CONSUMPTION AND ASSOCIATION WITH CARDIOVASCULAR DISEASE: A MULTI-COHORT STUDY FROM SWEDEN","authors":"Luka Marko Rašo, Ulf Hammar, Koen Dekkers, Susanna Larsson, Karl Michaëlsson, Marju Orho-Melander, Rikard Landberg, Gunnar Engström, J. Gustav Smith, Johan Ärnlöv, Lars Lind, Tove Fall, Shafqat Ahmad","doi":"10.1016/j.atherosclerosis.2026.120894","DOIUrl":"10.1016/j.atherosclerosis.2026.120894","url":null,"abstract":"","PeriodicalId":8623,"journal":{"name":"Atherosclerosis","volume":"419 ","pages":"Article 120894"},"PeriodicalIF":7.1,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148924411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
IL-21R BLOCKADE REDUCES ATHEROSCLEROSIS FORMATION IN YOUNG LDLR-/- MICE AND IMPAIRS PRO-ATHEROGENIC TFH-B CELL DYNAMICS UPON AGING Il-21r阻断可减少年轻ldlr -/-小鼠的动脉粥样硬化形成，并在衰老过程中损害促动脉粥样硬化的tfh-b细胞动力学
IF 7.1 2区 医学
Atherosclerosis Pub Date : 2026-08-01 Epub Date: 2026-09-09 DOI: 10.1016/j.atherosclerosis.2026.120897
Roy Snijckers, Virginia Smit, Rimke Postel, Marie Depuydt, Mireia Bernabé Kleijn, Ilze Bot, Johan Kuiper, Jill De Mol, Amanda Foks
{"title":"IL-21R BLOCKADE REDUCES ATHEROSCLEROSIS FORMATION IN YOUNG LDLR-/- MICE AND IMPAIRS PRO-ATHEROGENIC TFH-B CELL DYNAMICS UPON AGING","authors":"Roy Snijckers, Virginia Smit, Rimke Postel, Marie Depuydt, Mireia Bernabé Kleijn, Ilze Bot, Johan Kuiper, Jill De Mol, Amanda Foks","doi":"10.1016/j.atherosclerosis.2026.120897","DOIUrl":"10.1016/j.atherosclerosis.2026.120897","url":null,"abstract":"","PeriodicalId":8623,"journal":{"name":"Atherosclerosis","volume":"419 ","pages":"Article 120897"},"PeriodicalIF":7.1,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148924412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CHARACTERIZATION OF THE METABOLIC AND PROTEOMIC FINGERPRINTS ASSOCIATED WITH THE LIPC-E97G VARIANT INVOLVED IN COMBINED HYPOCHOLESTEROLEMIA 与合并低胆固醇血症相关的lipp - e97g变异的代谢和蛋白质组学指纹特征
IF 7.1 2区 医学
Atherosclerosis Pub Date : 2026-08-01 Epub Date: 2026-09-09 DOI: 10.1016/j.atherosclerosis.2026.120904
Chloé Cloteau, Perrine Benoît, Lucie Vince, Arsênio Rodrigues Oliveira, Samy Hadjadj, Bertrand Cariou, Cédric Le May, Mikael Croyal
{"title":"CHARACTERIZATION OF THE METABOLIC AND PROTEOMIC FINGERPRINTS ASSOCIATED WITH THE LIPC-E97G VARIANT INVOLVED IN COMBINED HYPOCHOLESTEROLEMIA","authors":"Chloé Cloteau, Perrine Benoît, Lucie Vince, Arsênio Rodrigues Oliveira, Samy Hadjadj, Bertrand Cariou, Cédric Le May, Mikael Croyal","doi":"10.1016/j.atherosclerosis.2026.120904","DOIUrl":"10.1016/j.atherosclerosis.2026.120904","url":null,"abstract":"","PeriodicalId":8623,"journal":{"name":"Atherosclerosis","volume":"419 ","pages":"Article 120904"},"PeriodicalIF":7.1,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148924413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
INTRODUCTION OF A PREMATURE STOP CODON IN APOLIPOPROTEIN B GENE RESHAPES LOW-DENSITY LIPOPROTEINS AND RESULTS IN REDUCTION OF CHOLESTEROL IN HYPERCHOLESTEROLEMIC MICE 在载脂蛋白b基因中引入过早停止密码子重塑低密度脂蛋白，导致高胆固醇血症小鼠胆固醇降低
IF 7.1 2区 医学
Atherosclerosis Pub Date : 2026-08-01 Epub Date: 2026-09-09 DOI: 10.1016/j.atherosclerosis.2026.120915
Cesare Canepari, Maurizio Cavallo, Marialucia Longo, Mauro Biffi, Vasco Meneghini, Michela Milani, Alessio Cantore
{"title":"INTRODUCTION OF A PREMATURE STOP CODON IN APOLIPOPROTEIN B GENE RESHAPES LOW-DENSITY LIPOPROTEINS AND RESULTS IN REDUCTION OF CHOLESTEROL IN HYPERCHOLESTEROLEMIC MICE","authors":"Cesare Canepari, Maurizio Cavallo, Marialucia Longo, Mauro Biffi, Vasco Meneghini, Michela Milani, Alessio Cantore","doi":"10.1016/j.atherosclerosis.2026.120915","DOIUrl":"10.1016/j.atherosclerosis.2026.120915","url":null,"abstract":"","PeriodicalId":8623,"journal":{"name":"Atherosclerosis","volume":"419 ","pages":"Article 120915"},"PeriodicalIF":7.1,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148916669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
MECHANISMS OF ATHEROSCLEROSIS REGRESSION 动脉粥样硬化消退的机制
IF 7.1 2区 医学
Atherosclerosis Pub Date : 2026-08-01 Epub Date: 2026-09-09 DOI: 10.1016/j.atherosclerosis.2026.120881
José Gabriel Barcia Durán, Morgane Gourvest, Michael Gildea, Sofie Delbare, Alexandra Newman, Tracy Zhang, Tarik Zahr, Whitney Rubin, Eduardo Esteva, Max La Forest, Hortense Le, Rami Vanguri, Igor Dolgalev, Edward Fisher, Kathryn Moore
{"title":"MECHANISMS OF ATHEROSCLEROSIS REGRESSION","authors":"José Gabriel Barcia Durán, Morgane Gourvest, Michael Gildea, Sofie Delbare, Alexandra Newman, Tracy Zhang, Tarik Zahr, Whitney Rubin, Eduardo Esteva, Max La Forest, Hortense Le, Rami Vanguri, Igor Dolgalev, Edward Fisher, Kathryn Moore","doi":"10.1016/j.atherosclerosis.2026.120881","DOIUrl":"10.1016/j.atherosclerosis.2026.120881","url":null,"abstract":"","PeriodicalId":8623,"journal":{"name":"Atherosclerosis","volume":"419 ","pages":"Article 120881"},"PeriodicalIF":7.1,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148916643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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