Xin Fu , Aomei Shen , Lichuan Zhang , Yujie Wang , Qian Lu
{"title":"Development and psychometric testing of the lymphedema self-management support scale for breast cancer survivors","authors":"Xin Fu , Aomei Shen , Lichuan Zhang , Yujie Wang , Qian Lu","doi":"10.1016/j.apjon.2024.100494","DOIUrl":"https://doi.org/10.1016/j.apjon.2024.100494","url":null,"abstract":"<div><h3>Objective</h3><p>Effective self-management support should be tailored to the individual. To provide personalized and targeted self-management support, a rigorous assessment tool is needed to screen the actual degree of lymphedema self-management support received by breast cancer survivors. This study aims to develop and psychometrically test the Lymphedema Self-Management Support Scale for Breast Cancer Survivors (LSMS-BCs).</p></div><div><h3>Methods</h3><p>This study involves two phases: scale development and psychometric testing. In the scale development phase, preliminary items and domains were identified through a qualitative meta-synthesis, a quantitative systematic review, and reference to previous similar scales. Expert consultation and pilot study were conducted to refine the scale and evaluate the content validity. The psychometric characteristics were tested with 447 participants using item analysis, exploratory factor analysis (EFA), confirmatory factor analysis (CFA), reliability assessments, as well as measurement invariance.</p></div><div><h3>Results</h3><p>A preliminary 21-item scale with four domains, basic management support, management support for limb volume reduction, role management support, and emotional management support, was constructed in the scale development phase and well supported by EFA and CFA. The scale-level content validity index was 0.983. Cronbach's α coefficient for overall scale and subscales ranged from 0.732 to 0.949. McDonald's ω ranged from 0.848 to 0.955. Excellent known-groups validity, concurrent validity, predictive validity, and measurement invariance were demonstrated.</p></div><div><h3>Conclusions</h3><p>The LSMS-BCs is psychometrically valid and reliable. It can serve as a valuable tool for assessing and understanding the lymphedema self-management support received by breast cancer survivors.</p></div>","PeriodicalId":8569,"journal":{"name":"Asia-Pacific Journal of Oncology Nursing","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2347562524001148/pdfft?md5=85ef7e57589765d81582bc49c4ad6ca4&pid=1-s2.0-S2347562524001148-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141067757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Communication in cancer care: An ongoing knowledge translation challenge","authors":"Sally Thorne","doi":"10.1016/j.apjon.2024.100489","DOIUrl":"10.1016/j.apjon.2024.100489","url":null,"abstract":"","PeriodicalId":8569,"journal":{"name":"Asia-Pacific Journal of Oncology Nursing","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2347562524001094/pdfft?md5=0ef567990b6439cf0d86a29f1dd187a6&pid=1-s2.0-S2347562524001094-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140776200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Role performance and factors affecting quality of life in bladder cancer survivors with ileal orthotopic neobladder","authors":"So Hee Kim , Eunjung Ryu , Byong Chang Jeong","doi":"10.1016/j.apjon.2024.100490","DOIUrl":"https://doi.org/10.1016/j.apjon.2024.100490","url":null,"abstract":"<div><h3>Objective</h3><p>Bladder cancer survivors with neobladder experience changes in role performance and quality of life (QoL) due to various symptoms and problems, but related studies are limited. Therefore, this study attempted to explore the QoL and factors influencing it in bladder cancer survivors with neobladder.</p></div><div><h3>Methods</h3><p>A cross–sectional descriptive design was used. Data were collected from 100 bladder cancer survivors with a neobladder using the European Organisation for Research and Treatment of Cancer QLQ–C30 and Muscle–Invasive Bladder Cancer Module, the Patient Activation Measure 13, the Enforced Social Dependency Scale, and the Multidimensional Scale of Perceived Social Support. Factors affecting the QoL were identified using multiple regression analysis.</p></div><div><h3>Results</h3><p>QoL significantly differed by daily pad usage, need for clean intermittent catheterization, and role performance. QoL was correlated with urinary symptoms and problems, future perspective, abdominal bloating and flatulence, body image, role performance, and social support. Role performance, body image, and the need for clean intermittent catheterization were identified as the factors affecting QoL.</p></div><div><h3>Conclusions</h3><p>The study highlights the importance of bladder cancer survivors continuing their roles at home, at work, and in society after neobladder reconstruction. Specifically, continuing recreational and social activity positively affects QoL, even if the activity range is modified. To help with their role performance, institutional support and changes in social perception are needed. Additionally, education and interventions, including body image enhancement, symptom management, and self–care, should be developed and applied to improve their QoL.</p></div>","PeriodicalId":8569,"journal":{"name":"Asia-Pacific Journal of Oncology Nursing","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2347562524001100/pdfft?md5=d8067ff6b67d07e57e55fa11422af0f0&pid=1-s2.0-S2347562524001100-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141077978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Stigma and quality of life in lung cancer patients: The mediating effect of distress and the moderated mediating effect of social support","authors":"Hyewon Lim , Hyunmi Son , Gyumin Han , Taehwa Kim","doi":"10.1016/j.apjon.2024.100483","DOIUrl":"10.1016/j.apjon.2024.100483","url":null,"abstract":"<div><h3>Objective</h3><p>This study aimed to investigate the mediating effect of distress on the relationship between stigma and quality of life (QOL) in lung cancer patients, and to explore the moderated mediating effect of social support.</p></div><div><h3>Methods</h3><p>A total of 184 individuals diagnosed with primary lung cancer participated in the study. Data on general and disease-related characteristics, stigma, distress, QOL, and social support were collected using a comprehensive structured questionnaire. Medical records were also utilized for an in-depth analysis of disease-related attributes. The data were meticulously analyzed using the SPSS PROCESS macro ver. 3.4 for detailed insights.</p></div><div><h3>Results</h3><p>The findings elucidated a clear pathway whereby stigma negatively impacted patients' QOL through the mediating effect of distress. Interestingly, the extent of this impact was significantly influenced by the presence of friendship support, underscoring its unique moderated mediating role. Conversely, support from family and health care professionals did not demonstrate a significant influence in this context.</p></div><div><h3>Conclusions</h3><p>These findings underscore the importance of addressing stigma and distress to improve the QOL of lung cancer patients. The study highlights the pivotal role of friendship support in moderating this relationship, suggesting the need for tailored interventions to strengthen social networks. These insights provide valuable guidance for developing more nuanced and effective patient support strategies in oncology care.</p></div>","PeriodicalId":8569,"journal":{"name":"Asia-Pacific Journal of Oncology Nursing","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2347562524001033/pdfft?md5=94122d33c7fcb27d3b7cf46c769d1dc8&pid=1-s2.0-S2347562524001033-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140775548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minyu Liang, Siying Zhu, Wenwen Zhang, M. Tish Knobf, Zengjie Ye
{"title":"Symptom network approach for management in cancer care","authors":"Minyu Liang, Siying Zhu, Wenwen Zhang, M. Tish Knobf, Zengjie Ye","doi":"10.1016/j.apjon.2024.100482","DOIUrl":"10.1016/j.apjon.2024.100482","url":null,"abstract":"","PeriodicalId":8569,"journal":{"name":"Asia-Pacific Journal of Oncology Nursing","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2347562524001021/pdfft?md5=4629556b440a1e0d61b3c71b7d910a1d&pid=1-s2.0-S2347562524001021-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140787796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lin Luo , Yidan Fan , Yanan Wang , Zhen Wang , Jian Zhou
{"title":"Prevalence and clinical outcomes of sarcopenia in patients with esophageal, gastric or colorectal cancers receiving preoperative neoadjuvant therapy: A meta-analysis","authors":"Lin Luo , Yidan Fan , Yanan Wang , Zhen Wang , Jian Zhou","doi":"10.1016/j.apjon.2024.100436","DOIUrl":"https://doi.org/10.1016/j.apjon.2024.100436","url":null,"abstract":"<div><h3>Objective</h3><p>To investigate the prevalence of sarcopenia and its impact on clinical outcomes in patients with esophageal, gastric, or colorectal cancer (EC, GC, and CRC) receiving neoadjuvant therapy through Meta-analysis.</p></div><div><h3>Methods</h3><p>We searched the PubMed, Embase databases, and Cochrane Library for the prevalence of sarcopenia and its impact on clinical outcomes in EC, GC, or CRC patients treated with neoadjuvant therapy (NAT) from inception to November 2022. The primary endpoints were the prevalence of sarcopenia and overall survival in patients with EC, GC, or CRC treated with NAT. Secondary outcomes included recurrence-free survival, total postoperative complications, grade 3–4 chemotherapy toxicity, and 30-day mortality after surgery.</p></div><div><h3>Results</h3><p>Thirty-one retrospective studies with 3651 subjects were included. In a fixed-effects model, the prevalence of muscle loss was higher in patients with EC, GC, or CRC at 50% (95% CI = 42% to 58%). The results of the multivariate analysis showed that preoperative patients with sarcopenia had a 1.91 times shorter overall survival (95% CI = 1.61–2.27) and a 1.77 times shorter recurrence-free survival time (95% CI = 1.33–2.35) than patients without sarcopenia, and that patients with sarcopenia had a higher risk of total postoperative complications than patients without sarcopenia OR = 1.27 (95% CI = 1.03–1.57). However, the two groups had no statistical difference in grade 3–4 chemotherapy toxicity (<em>P</em> = 0.84) or 30-d postoperative mortality (<em>P</em> = 0.88).</p></div><div><h3>Conclusions</h3><p>The prevalence of sarcopenia in patients with EC, GC, or CRC during NAT is high, and it is associated with poorer clinical outcomes. Clinicians should closely monitor the changes in patients’ body composition and guide patients to carry out a reasonable diet and appropriate exercise to improve their poor prognosis and quality of life.</p></div><div><h3>Systematic review registration</h3><p>CRD42023387817.</p></div>","PeriodicalId":8569,"journal":{"name":"Asia-Pacific Journal of Oncology Nursing","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2347562524000568/pdfft?md5=d05f3db6e6c4f57db0607c57bc7110b3&pid=1-s2.0-S2347562524000568-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140540056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wenqian Zhao, Winnie K.W. So, Huiyuan Li, Cho Lee Wong
{"title":"Knowledge, attitudes, and practices regarding cancer screening and primary prevention among ethnic minorities in mainland China: A literature review","authors":"Wenqian Zhao, Winnie K.W. So, Huiyuan Li, Cho Lee Wong","doi":"10.1016/j.apjon.2024.100435","DOIUrl":"https://doi.org/10.1016/j.apjon.2024.100435","url":null,"abstract":"<div><h3>Objective</h3><p>Cancer screening and primary prevention are effective strategies for addressing the burden of cancer. However, cancer health disparity exists in accessing cancer screening services among ethnic minorities in mainland China. Exploring knowledge, attitudes, and practices regarding cancer screening and primary prevention is an effective way to understand minority groups’ participation in these activities and the barriers to their participation. However, no review has summarized the relevant evidence. This study explored the evidence on cancer screening and primary prevention among ethnic minorities in mainland China, including their knowledge (knowledge level and awareness rate), attitudes (positive/negative attitudes, beliefs, and perceptions), and practices (uptake and participation rate).</p></div><div><h3>Methods</h3><p>Five online databases (MEDLINE, EMBASE, PubMed, China National Knowledge Infrastructure [CNKI], and Wanfang Data) were searched to identify literature. Data on knowledge, attitudes, and practices regarding cancer screening and primary prevention among ethnic minority groups and the influential factors were extracted and summarized.</p></div><div><h3>Results</h3><p>Twelve articles on studies with a total of 36,464 participants were included. Most of the studies focused only on breast and cervical cancer, women, and Uyghurs. The ethnic minority groups in the reviewed studies had a low level of knowledge about cancer screening and primary prevention and insufficient practices (cancer screening and primary prevention service uptake rate < 40.0%) but moderate to highly positive attitudes.</p></div><div><h3>Conclusions</h3><p>This review revealed the insufficient knowledge and practices of cancer screening and primary prevention among ethnic minority groups in mainland China, whose members hold generally positive attitudes toward screening. More evidence pertaining to diverse ethnic minority groups and other cancer types is needed.</p></div>","PeriodicalId":8569,"journal":{"name":"Asia-Pacific Journal of Oncology Nursing","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2347562524000556/pdfft?md5=3b552ae2755632633605d71b4ab5d481&pid=1-s2.0-S2347562524000556-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140350366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effects of meaning therapy on spirituality, psychological health, and quality of life in patients with cancer: A systematic review and meta-analysis of randomized controlled trials","authors":"Mimi Sun , Xia Tian , Yunyi Peng, Zheng Wang, Yongmei Lu, Wenli Xiao","doi":"10.1016/j.apjon.2024.100388","DOIUrl":"10.1016/j.apjon.2024.100388","url":null,"abstract":"<div><h3>Objective</h3><p>This study aimed to systematically review studies of meaning therapy on patients with cancer and to evaluate its effectiveness on spiritual outcomes, psychological outcomes, and quality of life (QOL).</p></div><div><h3>Methods</h3><p>A comprehensive literature search were performed in five international databases (PubMed, Embase, Web of Science, The Cochrane Library, and CINAHL) and four Chinese databases (CNKI, Wanfang Data, VIP, and CBM) from the inception to August 2023. The methodological quality of each included studies was evaluated by using the revised Cochrane risk-of-bias tool for randomized trials. The random-effects model or fixed-effects model was utilized for effect size analysis, and the standardized mean difference (SMD) or mean difference (MD) along with its corresponding 95% confidence interval (CI) was computed. Meta-analysis was conducted by using the RevMan software 5.4.1.</p></div><div><h3>Results</h3><p>Eight randomized controlled trials with 1251 participants were included in this review. Meta-analyses revealed that meaning therapy can significantly improve the spiritual outcomes including meaning in life (SMD = −0.48; 95% CI = −0.89 to −0.07; <em>P</em> = 0.02), hopelessness (SMD = −0.30; 95% CI = −0.51 to −0.09; <em>P</em> = 0.005), self-esteem (MD = −2.74; 95% CI = −4.17 to −1.32; <em>P</em> = 0.0002) and spiritual well-being (MD = −3.32; 95% CI = −5.63 to −1.01; <em>P</em> = 0.005), psychological outcomes including anxiety (MD = −0.66; 95% CI = −1.30 to −0.01; <em>P</em> = 0.05), depression (SMD = −0.37; 95% CI = −0.55 to −0.20; <em>P</em> < 0.0001), psychological distress (SMD = −0.35; 95% CI = −0.70 to −0.01; <em>P</em> = 0.04) and desire for hastened death (MD = −0.76; 95% CI = −1.47 to −0.05; <em>P</em> = 0.04), and QOL (SMD = −0.29; 95% CI = −0.50 to −0.09; <em>P</em> = 0.006) in patients with cancer.</p></div><div><h3>Conclusions</h3><p>Meaning therapy has positive effects on improving spirituality, psychological health, and QOL of patients with cancer. More high-quality randomized controlled trials with larger sample sizes are warranted to confirm the results of our review and to clarify the long-term effects of meaning therapy in the future.</p></div><div><h3>Systematic review registration</h3><p>PROSPERO (No. <span>CRD42021278286</span><svg><path></path></svg>).</p></div>","PeriodicalId":8569,"journal":{"name":"Asia-Pacific Journal of Oncology Nursing","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S234756252400012X/pdfft?md5=8c4733f0e92d1391c4dd43c9b822c59b&pid=1-s2.0-S234756252400012X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139879362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Binbin Xu , Winnie K.W. So , Kai Chow Choi , Yu Huang , Mei Liu , Lanxiang Qiu , Jianghong Tan , Hua Tao , Keli Yan , Fei Yang
{"title":"Financial toxicity and its risk factors among patients with cancer in China: A nationwide multisite study","authors":"Binbin Xu , Winnie K.W. So , Kai Chow Choi , Yu Huang , Mei Liu , Lanxiang Qiu , Jianghong Tan , Hua Tao , Keli Yan , Fei Yang","doi":"10.1016/j.apjon.2024.100443","DOIUrl":"10.1016/j.apjon.2024.100443","url":null,"abstract":"<div><h3>Objective</h3><p>We assessed financial toxicity (FT) among Chinese patients with cancer and investigated associated risk factors guided by a multilevel conceptual framework.</p></div><div><h3>Methods</h3><p>Applying multistage stratified sampling, we selected six tertiary and six secondary hospitals across three economically diverse provinces in China. From February to October 2022, 1208 patients with cancer participated. FT was measured using the COmprehensive Score for financial Toxicity (COST), with 28 potential risk factors identified at multilevel. Multiple regression analysis was used for risk factor identification.</p></div><div><h3>Results</h3><p>FT prevalence was 82.6% (95% confidence interval [CI]: 80.5%, 84.8%), with high FT (COST score ≤ 18.5) observed in 40.9% of participants (95% CI: 38.1%, 43.7%). Significant risk factors included younger age at cancer diagnosis, unmarried status, low annual household income, negative impact of cancer on participants' or family caregiver's work, advanced cancer stage, longer hospital stay for cancer treatment or treatment-related side effects, high perceived stress, poor emotional/informational support, lack of social medical insurance or having urban and rural resident basic medical insurance, lack of commercial medical insurance, tertiary hospital treatment, and inadequate cost discussions with healthcare providers (all <em>P</em> < 0.05).</p></div><div><h3>Conclusions</h3><p>Cancer-related FT is prevalent in China, contributing to disparities in cancer care access and health-related outcomes. The risk factors associated with cancer-related FT encompasses multilevel, including patient/family, provider/practice, and payer/policy levels. There is an urgent need for collective efforts by patients, healthcare providers, policymakers, and insurers to safeguard the financial security and well-being of individuals affected by cancer, promoting health equities in the realm of cancer care.</p></div>","PeriodicalId":8569,"journal":{"name":"Asia-Pacific Journal of Oncology Nursing","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2347562524000635/pdfft?md5=096ff44607c35a2fc5f22aa1b39dbbbe&pid=1-s2.0-S2347562524000635-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140276580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zimo Zhang , Li Tian , Juan Liu , Hua Jiang , Panfeng Wang
{"title":"Evidence summary on managing radiotherapy-induced oral mucositis in patients with head and neck cancer","authors":"Zimo Zhang , Li Tian , Juan Liu , Hua Jiang , Panfeng Wang","doi":"10.1016/j.apjon.2024.100386","DOIUrl":"10.1016/j.apjon.2024.100386","url":null,"abstract":"<div><h3>Objective</h3><p>To summarize the best evidence for managing radiotherapy-induced oral mucositis in patients with head and neck cancer, and improve the quality of care.</p></div><div><h3>Methods</h3><p>According to the “6S” evidence pyramid model, we searched local and other part of world published clinical guidelines, expert consensus, evidence summary, and systematic review. The literature quality assessment followed the Appraisal of Guidelines for Research and Evaluation (AGREE II). for guidelines, AMSTAR-2 for systematic reviews, and Joanna Briggs Institute (JBI) Evidence-Based Health Care Center's quality evaluation tool for expert opinions and expert consensus articles. The quality of other literature was evaluated according to the type of original literature. If there were any conflicts about the conclusions drawn from different sources of evidence, this study followed the principle of high-quality evidence priority and the latest published authoritative literature priority. The “JBI Evidence Pre-grading and Evidence Recommendation Level System 2014” was adopted for the evidence lacking a grading system. Quality evaluation, evidence extraction, and summary were performed by 2 or more researchers, combined with the advice of the head and neck cancer radiotherapy professionals.</p></div><div><h3>Results</h3><p>Finally, a total of ten pieces of literature were included. Twenty-two best evidence items for radiotherapy-induced oral mucositis management were summarized from six aspects, including multidisciplinary management, oral assessment, basic oral care, pain management, nutritional support, and application of honey or propolis.</p></div><div><h3>Conclusions</h3><p>This study provides clinical caregivers with the evidence-based measures on managing radiotherapy-induced oral mucositis. Clinical backgrounds, patients' condition, willingness, economy, and cost-effectiveness should be fully considered when promoting evidence transformation. Applying evidence-based approaches with high feasibility, strong appropriateness, clinical significance and high effectiveness could reduce the incidence of severe radiotherapy-induced oral mucositis in patients with head and neck cancer.</p></div><div><h3>Systematic review registration</h3><p>This study has been registered on the Fudan University Centre for Evidence-based Nursing. Registration No. is ES20232732.</p></div>","PeriodicalId":8569,"journal":{"name":"Asia-Pacific Journal of Oncology Nursing","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2347562524000106/pdfft?md5=9ce7b738311b05d1588245c1a7b0500f&pid=1-s2.0-S2347562524000106-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139636171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}