Asia-Pacific Journal of Oncology Nursing最新文献

{"title":"Bridging the gap and developing a home-based palliative care model for cancer patients","authors":"Zahra Alizadeh ,&nbsp;Camelia Rohani ,&nbsp;Maryam Rassouli ,&nbsp;Mahnaz Ilkhani ,&nbsp;Maryam Hazrati","doi":"10.1016/j.apjon.2024.100583","DOIUrl":"10.1016/j.apjon.2024.100583","url":null,"abstract":"<div><h3>Objective</h3><div>Early integration of palliative care into home health care services is essential for cancer patients to improve their Quality of Life and reduce their health care costs. Thus, this study aimed to develop a home-based palliative care model for adult cancer patients in Iran.</div></div><div><h3>Methods</h3><div>This is a health policy and systems research based on the World Health Organization guide. It consists of four phases; an integrative review, a qualitative study through individual semi-structured interviews (<em>n</em> = 37), and one focus group interview (<em>n</em> = 8), integrating these results in the third phase and generating model indicators. In the last phase, the evaluation of the importance of the indicators and the validation of the model were carried out during four classic Delphi rounds.</div></div><div><h3>Results</h3><div>Barriers to home-based palliative care were extracted from the first phase, and then 22 categories in eight pillars emerged from the qualitative phase. The indicators created for the model from two phases were integrated in the third phase (<em>n</em> = 118). After the four-round of the Delphi, a conceptual model for home-based palliative care in cancer patients, including 92 indicators within eight pillars was created.</div></div><div><h3>Conclusions</h3><div>Although this model was designed for our society, it can be utilized as a useful guide in other similar societies to design practical models and innovative programs to provide home-based palliative care in cancer patients. The application of the model in predicting different outcomes should be investigated in future trials.</div></div>","PeriodicalId":8569,"journal":{"name":"Asia-Pacific Journal of Oncology Nursing","volume":"11 11","pages":"Article 100583"},"PeriodicalIF":2.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142699521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiotoxicity in people undergoing cancer treatment - the role of the oncology nurse","authors":"Geraldine A. Lee ,&nbsp;Priya Reehal","doi":"10.1016/j.apjon.2024.100597","DOIUrl":"10.1016/j.apjon.2024.100597","url":null,"abstract":"<div><div>Cardiotoxicity is a significant complication of cancer treatment, and this review describes the cardiovascular risks associated with various therapies and emphasizes the crucial role of oncology nurses in managing these risks. Many cancer treatments, including cytotoxic therapies, radiation, targeted therapies, and immune-modulatory drugs, have been shown to increase the likelihood of cardiovascular toxicity, leading to conditions such as acute coronary syndrome, heart failure, and atrial fibrillation. Guidelines are now available to reduce treatment-related cardiovascular toxicity (CTR-CVT) and stress the importance of cardiovascular assessments before, during, and after cancer treatment. Oncology nurses are pivotal in performing these assessments and collaborating within multidisciplinary teams, including cardiologists, to ensure optimal care. As more patients successfully complete cancer treatment, it becomes essential to integrate cardiovascular risk evaluation, education, and medication into routine oncology care. The evolving field of oncology nursing, particularly with the rise of emerging therapies and aging populations, requires further education on early detection and management of cardiotoxicity to enhance patient outcomes.</div></div>","PeriodicalId":8569,"journal":{"name":"Asia-Pacific Journal of Oncology Nursing","volume":"11 11","pages":"Article 100597"},"PeriodicalIF":2.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142661731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Latent profile analysis of resilience and its influencing factors in patients with lung cancer undergoing chemotherapy","authors":"Sirui Zhang ,&nbsp;Limin Luo ,&nbsp;Liqun Zhou ,&nbsp;Lingying Ji ,&nbsp;Baogui Deng","doi":"10.1016/j.apjon.2024.100593","DOIUrl":"10.1016/j.apjon.2024.100593","url":null,"abstract":"<div><h3>Objective</h3><div>This study aims to analyze the classification characteristics of resilience in patients with lung cancer undergoing chemotherapy using latent profile analysis and explore the influencing factors and their relationship with medical coping strategies.</div></div><div><h3>Methods</h3><div>A questionnaire survey was conducted on 265 patients with lung cancer undergoing chemotherapy at a tertiary Grade-A hospital in Guangzhou from November 2023 to March 2024, using the General Information Questionnaire, Resilience Scale Specific to Cancer (RS-SC), Lung Cancer Chemotherapy Symptom Cluster Assessment Questionnaire, and Medical Coping Modes Questionnaire (MCMQ). Latent profile analysis was performed using Mplus 8.3 to identify resilience classifications, estimate influencing factors, and evaluate their impact on medical coping strategy selection.</div></div><div><h3>Results</h3><div>A total of 259 valid questionnaires were collected, with an effective response rate of 97.74%. Patients were categorized into three groups based on resilience levels: low-resilience group (20.46%), mid-resilience group (40.52%), and high-resilience group (38.97%). Multinomial logistic regression analysis revealed that education level, family per capita monthly income, and gastrointestinal and emotional symptom cluster scores were significant influencing factors for different resilience classifications (<em>P</em> &lt; 0.05). Statistically significant differences were found in the scores for the confrontation and resignation dimensions of medical coping strategies across different latent profiles (<em>P</em> &lt; 0.01).</div></div><div><h3>Conclusions</h3><div>Resilience in patients with lung cancer undergoing chemotherapy is heterogeneous, presenting in three distinct categories. Medical staff should provide tailored interventions based on the characteristics and influencing factors of each patient profile to enhance resilience and coping strategies.</div></div>","PeriodicalId":8569,"journal":{"name":"Asia-Pacific Journal of Oncology Nursing","volume":"11 11","pages":"Article 100593"},"PeriodicalIF":2.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142661449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of neurotoxic reactions induced by antibody-drug conjugates","authors":"Jie Zhang ,&nbsp;Hong Yang ,&nbsp;Yuhan Lu","doi":"10.1016/j.apjon.2024.100595","DOIUrl":"10.1016/j.apjon.2024.100595","url":null,"abstract":"<div><div>In recent years, many new antitumor drugs have been approved for clinical use. Among them, antibody-drug conjugates (ADCs) are an innovative drug group that combines the advantages of chemotherapy with a cytotoxic drug and targeted therapy with monoclonal antibodies. However, although ADCs provide survival benefits to patients, their special composition and mode of action also lead to specific adverse effects. Among the common adverse effects caused by ADCs, peripheral neuropathy (PN) affects patients’ quality of life and also present significant challenges to clinical nursing. There are several guidelines and consensus for treating chemotherapy-induced peripheral neuropathy. However, there are no specific guidelines for managing PN caused by ADCs. Nurses play an important role in the prevention and management of PN, and their relevant knowledge and skills for symptom assessment, functional deficit screening, patient referral and advocacy, and patient education are indispensable. By combining Chinese and international guidelines, consensus, and related studies, this paper reviewed the occurrence and characteristics of ADC-induced PN and highlighted the principles of prevention, treatment, and nursing care to provide a reference for clinical nursing practice and improve the safety of ADCs for patients.</div></div>","PeriodicalId":8569,"journal":{"name":"Asia-Pacific Journal of Oncology Nursing","volume":"11 11","pages":"Article 100595"},"PeriodicalIF":2.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142661448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of shared decision-making in patients with breast cancer undergoing breast reconstruction surgery: A systematic review and meta-analysis","authors":"Lixia Chen ,&nbsp;Jia Lu ,&nbsp;Bo Chen ,&nbsp;Xiaoxia Zhang","doi":"10.1016/j.apjon.2024.100596","DOIUrl":"10.1016/j.apjon.2024.100596","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Objective&lt;/h3&gt;&lt;div&gt;Patients with breast cancer who must undergo breast mastectomy are offered different types of breast reconstruction surgeries. Shared decision-making (SDM) is an important emerging intervention in the decision-making process of patients. This study aimed to evaluate the effects of SDM in patients with breast cancer undergoing breast reconstruction surgery.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;div&gt;Databases, including China National Knowledge Infrastructure, Wanfang, Chinese Biomedical Database, VIP, PubMed, Cochrane Library, Web of Science, Cumulative Index to Nursing and Allied Health Literature, and Embase, were searched for articles on the application of SDM in patients undergoing breast reconstruction. The literature search retrieval time limit was from inception to February 29, 2024, with Chinese and English language restrictions. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses checklist was used for reporting this work. The randomized controlled trial (RCT) quality was assessed using The Cochrane Collaboration's tool for assessing risk of bias and quasi-randomized trials using Joanna Briggs Institute's critical appraisal tools. The SDM effects on decisional conflict, regret, knowledge, participation, and satisfaction, anxiety, and depression were assessed. Revman5.4 software was used for the meta-analysis.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;In total, 18 papers out of 854 records identified from the database search met the eligibility criteria, including 16 articles in English and two articles in Chinese. There were 12 RCTs and six quasi-randomized trials. The meta-analysis results revealed that SDM could reduce decisional conflict [mean difference (MD), −4.49; 95% confidence interval (CI) (−6.70, −2.27); &lt;em&gt;P&lt;/em&gt; &lt; 0.001], decisional regret [MD, −6.06; 95% CI (−9.51, −2.61); &lt;em&gt;P&lt;/em&gt; &lt; 0.001], and depression [standardized mean difference (SMD), −0.67; 95% CI (−0.99, −0.35); &lt;em&gt;P&lt;/em&gt; &lt; 0.001] in patients who underwent breast reconstruction surgery. In addition, SDM can improve decisional participation [SMD, 0.30; 95% CI (0.11, 0.49); &lt;em&gt;P&lt;/em&gt; = 0.002] and decisional knowledge [SMD, 0.43; 95% CI (0.11, 0.75); &lt;em&gt;P&lt;/em&gt; = 0.009], but with no significant improvement in decisional satisfaction [SMD, 0.30; 95% CI (−0.35, 0.94); &lt;em&gt;P&lt;/em&gt; = 0.37] and anxiety [SMD, −0.09; 95% CI (−0.22, 0.04); &lt;em&gt;P&lt;/em&gt; = 0.17]. The subgroup analysis of country/region showed that the interventional effect of SDM in Western countries [MD, −3.84; 95% CI (−4.16, −3.52); &lt;em&gt;P&lt;/em&gt; &lt; 0.001] was stronger than that in Eastern countries [MD, −1.81; 95% CI (−2.32, −1.30); &lt;em&gt;P&lt;/em&gt; &lt; 0.001], and the interventional effect of Booklet group [MD, −6.92; 95% CI (−8.90, −4.94); &lt;em&gt;P&lt;/em&gt; &lt; 0.001] was stronger than that of Computer-based group [MD, −3.23; 95% CI (−3.50, −2.96); &lt;em&gt;P&lt;/em&gt; &lt; 0.001].&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Conclusions&lt;/h3&gt;&lt;div&gt;SDM shows positive effects in many aspects in patients with ","PeriodicalId":8569,"journal":{"name":"Asia-Pacific Journal of Oncology Nursing","volume":"11 11","pages":"Article 100596"},"PeriodicalIF":2.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142661450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of auricular acupressure in managing sleep quality, mood, and quality of life in parents of children with cancer: A pilot randomized controlled trial","authors":"Yi-Chien Chiang ,&nbsp;Shih-Hsiang Chen ,&nbsp;Debra K. Moser ,&nbsp;Yu-Chuan Wen ,&nbsp;Yu-Ting Lin ,&nbsp;Ya-Chu Hsiao","doi":"10.1016/j.apjon.2024.100601","DOIUrl":"10.1016/j.apjon.2024.100601","url":null,"abstract":"<div><h3>Objective</h3><div>This pilot study aimed to assess the feasibility and effectiveness of an auricular acupressure intervention on sleep quality, mood state, and quality of life (QOL) among parents of children with cancer.</div></div><div><h3>Methods</h3><div>Thirty-five parents were assigned to three-weeks intervention in an active auricular acupressure group (AAG) or a sham auricular acupressure group (SAG). Feasibility was assessed by adherence to the acupressure protocol. Outcomes were measured using the Pittsburgh Sleep Quality Index for sleep quality, the Profile of Mood States for mood, and the QOL short form for QOL. The data were analyzed using generalized estimating equations to identify changes over time within and between the groups.</div></div><div><h3>Results</h3><div>Adherence to the protocol was 78%. There were no differences between the groups in overall sleep quality or mood state, but QOL in the Physical Component Summary was better in the AAG at time 1. Parents in the AAG exhibited significantly higher levels of vigor compared to those in the SAG group. Statistically significant differences were observed in the Physical Functioning and General Health subscales, with the AAG showing better outcomes than the SAG group at time 1 and time 2, respectively.</div></div><div><h3>Conclusions</h3><div>Likely due to the small sample size, the AAG and SAG did not differ in overall sleep quality, mood state, or QOL, but there were significant subscale differences that support intervention effectiveness. A fully powered large-scale trial is needed to determine whether this intervention would be effective for parents of children with cancer. Reducing symptom distress and improving QOL in these parents are essential, and interventions to achieve this goal must be tested.</div></div><div><h3>Trial registration</h3><div>ClinicalTrials.gov NCT05654155.</div></div>","PeriodicalId":8569,"journal":{"name":"Asia-Pacific Journal of Oncology Nursing","volume":"11 11","pages":"Article 100601"},"PeriodicalIF":2.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142661451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role experiences of women with breast cancer as daughters: A qualitative meta-synthesis","authors":"Mengjiao Xu,&nbsp;Linping Zhang,&nbsp;Mi Zhao,&nbsp;Suting Zhang,&nbsp;Ting Luo,&nbsp;Ying Zhu,&nbsp;Jing Han","doi":"10.1016/j.apjon.2024.100599","DOIUrl":"10.1016/j.apjon.2024.100599","url":null,"abstract":"<div><h3>Objective</h3><div>To synthesize qualitative data on the role experiences of women with breast cancer as daughters, and thereby provide inspiration and reference for psychological and social interventions for these patients and their families.</div></div><div><h3>Methods</h3><div>Six English databases (PubMed, Web of Science, CINAHL, Embase, Cochrane Library, and Joanna Briggs Institute) and four Chinese databases (CNKI, Wanfang, VIP, and CBM) were searched from inception to June 2024 to retrieve qualitative or mixed-methods studies on the role experiences of women with breast cancer as daughters. The Joanna Briggs Institute Critical Appraisal Tool for qualitative research was used to evaluate study quality, and the results were integrated using a meta-aggregation approach.</div></div><div><h3>Results</h3><div>Eighteen studies were included in this meta-synthesis: 37 findings were extracted and aggregated into 10 categories and three synthesized findings. Synthesized findings focused on negative experiences in the role of daughter; positive experiences in the role of daughter; and support needs in the role of daughter. The confidence of all synthesized findings was moderate.</div></div><div><h3>Conclusions</h3><div>Emphasis should be placed on the role experiences of women with breast cancer as daughters, and targeted practical assistance and professional support should be provided to promote the stable development of the patient’s relationship with their parents and enhance the coping ability of both patients and their families.</div></div><div><h3>Systematic review registration</h3><div>PROSPERO, CRD42023456567.</div></div>","PeriodicalId":8569,"journal":{"name":"Asia-Pacific Journal of Oncology Nursing","volume":"11 11","pages":"Article 100599"},"PeriodicalIF":2.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142661732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evidence summary on perioperative non-pharmacological prophylaxis of venous thromboembolism in patients with pancreatic cancer","authors":"Ni Yang ,&nbsp;Yuan Xu ,&nbsp;Haoran Shi ,&nbsp;Jianhua Sun ,&nbsp;Yufen Ma ,&nbsp;Shuli Guo ,&nbsp;Ying Liu ,&nbsp;Ranxun An ,&nbsp;Xinyi Zhou","doi":"10.1016/j.apjon.2024.100592","DOIUrl":"10.1016/j.apjon.2024.100592","url":null,"abstract":"<div><h3>Objective</h3><div>To summarize the best evidence related to perioperative non-pharmacologic prophylaxis of venous thromboembolism in patients with pancreatic cancer, and improve the quality of clinical practice.</div></div><div><h3>Methods</h3><div>According to the “6S” evidence pyramid model, we searched guideline networks, professional society websites, and comprehensive databases for clinical decisions, clinical guidelines, expert consensus, evidence summaries, and systematic reviews related to perioperative non-pharmacological prophylaxis of venous thromboembolism in patients with pancreatic cancer. The literature quality assessment followed appropriate tools. If there were any conflicts about the conclusions drawn from different sources of evidence, this study followed the principle of high-quality evidence and the latest published authoritative literature priority. The “JBI Evidence Pre-grading and Evidence Recommendation Level System 2014” was adopted for the evidence lacking a grading system.</div></div><div><h3>Results</h3><div>Nineteen studies were included, including 7 guidelines, 5 expert consensus, 2 clinical decisions, 3 evidence summaries, and 2 systematic reviews. Twenty-three pieces of best evidence were summarized in five aspects: risk assessment, mechanical prophylactic devices, initiation and duration of non-pharmacological prevention, implementation strategies, and health education.</div></div><div><h3>Conclusions</h3><div>The 23 pieces of evidence in five aspects we summarized provide scientific references for clinical caregivers to develop perioperative venous thromboembolism prophylaxis for pancreatic cancer patients. In addition, in order for evidence to be effectively used to improve the quality of clinical practice, clinical caregivers should consider patient preferences and explore barriers to the evidence translation and application.</div></div><div><h3>Systematic review registration</h3><div>This study has been registered on the Fudan University Centre for Evidence-based Nursing (Registation No. ES20233506).</div></div>","PeriodicalId":8569,"journal":{"name":"Asia-Pacific Journal of Oncology Nursing","volume":"11 11","pages":"Article 100592"},"PeriodicalIF":2.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142661446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validating performance status and activities of daily living assessment tools for Chinese palliative care in a cancer setting: A cross-cultural psychometric study","authors":"Yunyun Dai ,&nbsp;Jinfeng Ding ,&nbsp;Barbara A. Daveson ,&nbsp;Yongyi Chen ,&nbsp;Alanna Connolly ,&nbsp;Claire E. Johnson","doi":"10.1016/j.apjon.2024.100613","DOIUrl":"10.1016/j.apjon.2024.100613","url":null,"abstract":"<div><h3>Objective</h3><div>National approaches to the routine assessment of palliative care patients improve patient outcomes. However, validated tools and a national methodology for this are lacking in Mainland China. The Australian Palliative Care Outcomes Collaboration (PCOC) model is a well-established national program aimed at improving the quality of palliative care based on point-of-care outcomes assessment. This study aimed to culturally adapt and validate two measures used in PCOC (Australia-modified Karnofsky Performance Status [AKPS], Resource Utilization Groups - Activities of Daily Living [RUG-ADL]) in the Chinese context.</div></div><div><h3>Methods</h3><div>A cross-cultural adaptation and validation study involving forward and backward translation methods, cognitive interviewing, and psychometric testing.</div></div><div><h3>Results</h3><div>Two minor adjustments were made to the scoring instructions for the RUG-ADL, and the AKPS remained unchanged. Twenty-two clinicians participated in psychometric testing, completing 363 paired assessments on 135 inpatients. The correlations between AKPS and the Barthel index (BI) for activities of daily living (<em>r</em> = 0.77, <em>P</em> &lt; 0.001), AKPS and RUG-ADL (<em>r</em> = −0.82, <em>P</em> &lt; 0.001), RUG-ADL and BI (<em>r</em> = −0.67 to −0.76) demonstrated good concurrent validity for both the AKPS and the RUG-ADL. The inter-rater reliability for AKPS (<em>k</em> = 0.63) and RUG-ADL were substantial and moderate (<em>k</em> = 0.51–0.56), respectively. The RUG-ADL also showed good internal consistency (Cronbach's alpha = 0.92). Both tools were able to detect patients' urgent needs.</div></div><div><h3>Conclusions</h3><div>The Chinese version of AKPS and RUG-ADL can be systematically used to assess performance status and dependency among palliative care patients. However, observational assessments and enhanced communication between clinicians and patients/caregivers is also recommended for optimal clinical utility.</div></div>","PeriodicalId":8569,"journal":{"name":"Asia-Pacific Journal of Oncology Nursing","volume":"11 12","pages":"Article 100613"},"PeriodicalIF":2.4,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142698795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Symptom clusters and network analysis in patients with gynecologic cancer undergoing chemotherapy: A cross-sectional study","authors":"Jiajia Zhang ,&nbsp;Shan Wang ,&nbsp;Yuan Wang ,&nbsp;Jiaru Zhuang ,&nbsp;Ling Hang ,&nbsp;Yibo Wu ,&nbsp;Dewu Xu ,&nbsp;Chunyan Huang","doi":"10.1016/j.apjon.2024.100612","DOIUrl":"10.1016/j.apjon.2024.100612","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to explore the complex relationships among symptoms and symptom clusters in patients with gynecologic cancer receiving chemotherapy using symptom network analysis, and to identify core symptoms and core symptom clusters.</div></div><div><h3>Methods</h3><div>A cross-sectional study was conducted at the Affiliated Hospital of Jiangnan University from December 2023 to June 2024, including 221 patients with gynecologic tumors. Participants completed demographic and clinical information questionnaires and the Chinese version of the MD Anderson Symptom Inventory (MDASI-C). Univariate analysis and multiple linear regression were used to screen covariates, exploratory factor analysis to determine symptom clusters, and network analysis to identify core symptoms and core symptom clusters.</div></div><div><h3>Results</h3><div>A total of 221 patients were included, with an average age of 58.73 years (SD = 11.50). Fatigue (<em>n</em> = 197, 89.1%) and lack of appetite (<em>n</em> = 192, 86.9%) were the most common symptoms, while fatigue (mean = 4.17, SD = 2.07) and distress (mean = 3.43, SD = 2.20) were the most severe symptoms. Several distinct symptom clusters were identified: sickness behavior, gastrointestinal, psychological, and side-effect clusters. In the constructed network, fatigue emerged as the most central symptom (rs = 1.28), while the sickness behavior cluster was identified as the most central symptom cluster (rs = 1.11).</div></div><div><h3>Conclusions</h3><div>Patients with gynecologic cancer undergoing chemotherapy commonly experience a range of symptoms. Our findings suggest that targeted interventions focusing on the sickness behavior symptom cluster may help reduce the overall symptom burden and assist caregivers in developing more effective symptom management strategies.</div></div>","PeriodicalId":8569,"journal":{"name":"Asia-Pacific Journal of Oncology Nursing","volume":"11 12","pages":"Article 100612"},"PeriodicalIF":2.4,"publicationDate":"2024-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142698892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}