Jianqiang Wang, Haoshuang Geng, Lijin Zhou, Yong Hai
{"title":"Complications and curve progression in EOS patients with extended distraction surgery intervals in growing rod surgery: a retrospective cohort study in China.","authors":"Jianqiang Wang, Haoshuang Geng, Lijin Zhou, Yong Hai","doi":"10.31616/asj.2024.0426","DOIUrl":"https://doi.org/10.31616/asj.2024.0426","url":null,"abstract":"<p><strong>Study design: </strong>Retrospective case-control study.</p><p><strong>Purpose: </strong>This study aimed to explore the relationship between the rod-lengthening interval and the incidence of postoperative complications as well as the outcomes in patients with early-onset scoliosis (EOS) undergoing growing rod surgery.</p><p><strong>Overview of literature: </strong>EOS is characterized by a spinal deformity that manifests before the age of 10 years. The growing rod technique allows for spinal curvature correction while preserving spinal growth through periodic lengthening surgeries typically performed every 6 months. However, we found that due to challenges, many patients undergo a 1-year or even longer interval between lengthening surgeries.</p><p><strong>Methods: </strong>We conducted a retrospective analysis of 59 patients with EOS who underwent growing rod surgery at our institution between August 2012 and June 2022. We collected radiographic parameters to compare the differences in outcomes and complications between patients who underwent lengthening surgeries at intervals of 12 months versus those with intervals of >12 months.</p><p><strong>Results: </strong>In this study, we found 29 complications in 59 patients. The complication rate was significantly lower in the group with lengthening intervals of 12 months compared with the group with intervals longer than 12 months (35.3% vs. 68%, p <0.05). In addition, patients in the group with intervals of 12 months showed less progression of the main curve, a lower maximum kyphosis angle, and greater increases in height in the fixed segments (d=7.53±3.69 cm, p <0.05). In contrast, patients with lengthening intervals longer than 12 months were more likely to experience sagittal plane imbalance (p <0.05).</p><p><strong>Conclusions: </strong>Lengthening intervals of greater than 12 months have a higher rate of complications and increase the risk of curve progression and spinal imbalance. Increasing the interval time just to minimize the number of surgeries before the final fusion is unwise.</p>","PeriodicalId":8555,"journal":{"name":"Asian Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143540031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Young-Hoon Kim, Ki-Won Kim, Kee-Won Rhyu, Jong-Beom Park, Jae-Hyuk Shin, Young-Yul Kim, Jun-Seok Lee, Joong-Hyun Ahn, Ji-Hyun Ryu, Hyung-Youl Park, Sang-Il Kim
{"title":"Bone fusion materials: past, present, and future.","authors":"Young-Hoon Kim, Ki-Won Kim, Kee-Won Rhyu, Jong-Beom Park, Jae-Hyuk Shin, Young-Yul Kim, Jun-Seok Lee, Joong-Hyun Ahn, Ji-Hyun Ryu, Hyung-Youl Park, Sang-Il Kim","doi":"10.31616/asj.2024.0520","DOIUrl":"https://doi.org/10.31616/asj.2024.0520","url":null,"abstract":"<p><p>Bone fusion is one of the mainstay managements for degenerative spinal diseases and critical-sized bone defects resulting from trauma, tumors, infection, and nonunion. Bone graft materials are required for promoting bone healing, with autografts historically considered the gold standard due to their osteogenic, osteoinductive, and osteoconductive properties. However, donor site morbidities have led to the development of alternative bone graft substitutes. Currently available alternative options for bone fusion include allografts, ceramics, demineralized bone matrix (DBM), and bone morphogenetic proteins (BMPs). Each material has its advantages and disadvantages. Allografts avoid donor site morbidities but lack osteogenic properties and pose disease transmission risks. DBMs are acid-extracted allografts that have osteoconductive and osteoinductive properties but require combination with autografts because of the lack of evidence for their stand-alone use. BMP-2 has potent osteoinductive properties and is considered an ideal fusion material, but faces unresolved challenges related to optimal dosage and carrier. Synthetic peptides, mimicking the cell-binding domain of type I collagen, facilitate the attachment of osteogenic cells (such as osteoblasts) to the graft material and the production of extracellular matrix, leading to improved bone growth at the fusion site. The development of materials with ideal properties is a research hotspot. Recent advancements in biomaterials, such as hydrogels, nanomaterials, and three-dimensional-printed biomaterials, offer promising future options for bone fusion. This review provides an overview of available bone fusion materials, their advantages and disadvantages, and introduces emerging candidate options for bone fusion.</p>","PeriodicalId":8555,"journal":{"name":"Asian Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143188038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Asian Spine JournalPub Date : 2025-02-01Epub Date: 2025-02-24DOI: 10.31616/asj.2024.0491
Victoria Yuk Ting Hui, Jason Pui Yin Cheung, Prudence Wing Hang Cheung
{"title":"Lateral view fulcrum bending radiographs predict postoperative hypokyphosis after selective thoracic fusion in adolescent idiopathic scoliosis.","authors":"Victoria Yuk Ting Hui, Jason Pui Yin Cheung, Prudence Wing Hang Cheung","doi":"10.31616/asj.2024.0491","DOIUrl":"10.31616/asj.2024.0491","url":null,"abstract":"<p><strong>Study design: </strong>A retrospective observational study.</p><p><strong>Purpose: </strong>To identify the surgical and preoperative risk factors on fulcrum bending radiographs for postoperative hypokyphosis in patients with Lenke 1 adolescent idiopathic scoliosis (AIS).</p><p><strong>Overview of literature: </strong>AIS is associated with thoracic hypokyphosis. Persistent hypokyphosis causes reduced pulmonary function and spinopelvic malalignment. Indications for Ponte osteotomies and releases to improve postoperative kyphosis restoration in patients with hypokyphosis are still unclear. Previous studies have demonstrated that kyphosis correction was limited by sagittal flexibility based on lateral view fulcrum bending radiographs.</p><p><strong>Methods: </strong>Patients with Lenke 1 AIS undergoing posterior spinal fusion were included. Standing and fulcrum bending radiographs on the coronal and sagittal planes were analyzed at preoperative, immediate, and 2-year postoperative periods. The primary outcome was postoperative hypokyphosis (T5-12 thoracic kyphosis [TK] <20°). Risk factors for postoperative hypokyphosis were identified by multivariate logistic regression, and the optimal cutoff for significant risk factors was determined by receiver operating characteristic analysis.</p><p><strong>Results: </strong>In total, 156 patients were included in the analysis, of which 68 (43.6%) were hypokyphotic at 2-year follow-up. Low T5-12 TK on lateral view fulcrum bending films (immediate postoperative odds ratio [OR], 0.870; 95% confidence interval [CI], 0.826-0.917; 2-year postoperative OR, 0.916; 95% CI, 0.876-0.959; p<0.001) and high convex side implant density (2-year postoperative OR, 1.749; 95% CI, 1.056-2.897; p=0.03) were significant risk factors for postoperative hypokyphosis. Other baseline demographic and surgical factors did not affect postoperative kyphosis correction. The T5-12 TK cutoff on fulcrum bending for 2-year postoperative hypokyphosis was 12.45° (area under the curve, 0.773; 95% CI, 0.661-0.820).</p><p><strong>Conclusions: </strong>Fulcrum bending radiography is useful in assessing coronal and sagittal flexibility for preoperative planning. In patients with T5-12 kyphosis <12.5° on lateral view fulcrum bending radiographs, Ponte osteotomies or releases, or a decrease in convex side implant density should be considered to improve kyphosis restoration and reduce the risk of 2-year postoperative hypokyphosis.</p>","PeriodicalId":8555,"journal":{"name":"Asian Spine Journal","volume":"19 1","pages":"102-111"},"PeriodicalIF":2.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11895112/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143555717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Asian Spine JournalPub Date : 2025-02-01Epub Date: 2025-01-20DOI: 10.31616/asj.2024.0452
Wongthawat Liawrungrueang, Sung Tan Cho, Watcharaporn Cholamjiak, Peem Sarasombath, Nattaphon Twinprai, Prin Twinprai, Inbo Han
{"title":"Performance and clinical implications of machine learning models for detecting cervical ossification of the posterior longitudinal ligament: a systematic review.","authors":"Wongthawat Liawrungrueang, Sung Tan Cho, Watcharaporn Cholamjiak, Peem Sarasombath, Nattaphon Twinprai, Prin Twinprai, Inbo Han","doi":"10.31616/asj.2024.0452","DOIUrl":"10.31616/asj.2024.0452","url":null,"abstract":"<p><p>Ossification of the posterior longitudinal ligament (OPLL) is a significant spinal condition that can lead to severe neurological deficits. Recent advancements in machine learning (ML) and deep learning (DL) have led to the development of promising tools for the early detection and diagnosis of OPLL. This systematic review evaluated the diagnostic performance of ML and DL models and clinical implications in OPLL detection. A systematic review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. PubMed/Medline and Scopus databases were searched for studies published between January 2000 and September 2024. Eligible studies included those utilizing ML or DL models for OPLL detection using imaging data. All studies were assessed for the risk of bias using appropriate tools. The key performance metrics, including accuracy, sensitivity, specificity, and area under the curve (AUC), were analyzed. Eleven studies, comprising a total of 6,031 patients, were included. The ML and DL models demonstrated high diagnostic performance, with accuracy rates ranging from 69.6% to 98.9% and AUC values up to 0.99. Convolutional neural networks and random forest models were the most used approaches. The overall risk of bias was moderate, and concerns were primarily related to participant selection and missing data. In conclusion, ML and DL models show great potential for accurate detection of OPLL, particularly when integrated with imaging techniques. However, to ensure clinical applicability, further research is warranted to validate these findings in more extensive and diverse populations.</p>","PeriodicalId":8555,"journal":{"name":"Asian Spine Journal","volume":" ","pages":"148-159"},"PeriodicalIF":2.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11895113/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142999027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Asian Spine JournalPub Date : 2025-02-01Epub Date: 2025-02-24DOI: 10.31616/asj.2024.0127
Myung-Sang Moon
{"title":"History of Western Pacific Orthopedic Association, Western Pacific Orthopedic Association Spine Section, and Asian Spine Journal.","authors":"Myung-Sang Moon","doi":"10.31616/asj.2024.0127","DOIUrl":"10.31616/asj.2024.0127","url":null,"abstract":"","PeriodicalId":8555,"journal":{"name":"Asian Spine Journal","volume":"19 1","pages":"1-2"},"PeriodicalIF":2.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11895106/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143555742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Asian Spine JournalPub Date : 2025-02-01Epub Date: 2025-02-24DOI: 10.31616/asj.2025.0001.r1
Hinpetch Daungsupawong, Viroj Wiwanitkit
{"title":"Letter to the editor: Validation of the visual body image classification in adolescent idiopathic scoliosis.","authors":"Hinpetch Daungsupawong, Viroj Wiwanitkit","doi":"10.31616/asj.2025.0001.r1","DOIUrl":"10.31616/asj.2025.0001.r1","url":null,"abstract":"","PeriodicalId":8555,"journal":{"name":"Asian Spine Journal","volume":"19 1","pages":"162-163"},"PeriodicalIF":2.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11895136/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143555783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Which subtypes of degenerative lumbar spondylolisthesis are suitable for oblique lumbar interbody fusion? A retrospective study in China based on the clinical and radiographic degenerative spondylolisthesis classification.","authors":"Xianghe Wang, Hongwei Wang, Xiaosheng Ma, Xinlei Xia, Feizhou Lyu, Haocheng Xu, Hongli Wang","doi":"10.31616/asj.2024.0310","DOIUrl":"10.31616/asj.2024.0310","url":null,"abstract":"<p><strong>Study design: </strong>Retrospective study.</p><p><strong>Purpose: </strong>To evaluate the radiological characteristics of degenerative lumbar spondylolisthesis (DS) and analyze the suitability of oblique lumbar interbody fusion (OLIF) for different DS subtypes.</p><p><strong>Overview of literature: </strong>OLIF has gained distinction for its minimal invasiveness and quicker recovery. Despite its promising effectiveness in treating DS, variations in patient characteristics necessitate precise surgical technique selection. The clinical and radiographic degenerative spondylolisthesis (CARDS) classification aids in identifying suitable DS subtypes.</p><p><strong>Methods: </strong>From March 2020 to March 2023, 100 inpatients with DS were classified into groups A, B, C, and D based on the CARDS classification system. Preoperative radiological data were analyzed to measure the severity of central canal stenosis, facet joint arthropathy, intervertebral disc herniation, and spinal epidural lipomatosis, osteophyte formation, range of motion (ROM), and computed tomography value of the vertebral bodies. The radiological characteristics and clinical contraindications for OLIF were compared among the groups.</p><p><strong>Results: </strong>Of the 100 patients, 51% had clinical contraindications for OLIF, which included 85%, 25%, 62.5%, and 20% of patients in groups A, B, C, and D, respectively. Compared with group B, group A demonstrated greater severity of central canal stenosis, whereas group C showed a higher degree of facet joint arthropathy. More patients in groups A and C had severe central canal stenosis. Regarding the ROM results, group A had segmental stiffness, whereas group D presented relatively unstable slip segments.</p><p><strong>Conclusions: </strong>Patients with different DS subtypes have varied radiological characteristics. Groups B and D are suitable candidates for OLIF. Most patients in group A are unsuitable for OLIF because of bony hyperplasia, severe spinal stenosis, and segmental stiffness.</p>","PeriodicalId":8555,"journal":{"name":"Asian Spine Journal","volume":"19 1","pages":"112-120"},"PeriodicalIF":2.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11895115/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143555785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hybrid decompression-based surgical strategy for treating multilevel thoracic ossification of the ligamentum flavum: a retrospective study.","authors":"Cong Nie, Kaiwen Chen, Shenyan Gu, Feizhou Lyu, Jianyuan Jiang, Xinlei Xia, Chaojun Zheng","doi":"10.31616/asj.2024.0366","DOIUrl":"10.31616/asj.2024.0366","url":null,"abstract":"<p><strong>Study design: </strong>A retrospective study design was adopted.</p><p><strong>Purpose: </strong>This study investigated the surgical modification of laminectomy, including piecemeal and en bloc resections, and compared this hybrid approach with conventional en bloc laminectomy for treating multilevel thoracic ossification of the ligamentum flavum (TOLF).</p><p><strong>Overview of literature: </strong>En bloc laminectomy is the most commonly used method for managing symptomatic TOLF. However, this approach can easily cause intraoperative spinal cord irritation, dural tear, and cerebrospinal fluid leakage (CFL).</p><p><strong>Methods: </strong>Motor-evoked potentials (MEPs) and somatosensory-evoked potentials (SEPs) were recorded in 48 patients with TOLF (hybrid 20 vs. en bloc 28) during surgery. Patients were categorized based on MEP/SEP improvement, deterioration, or no change, and MEP/SEP improvement rates were measured in the improvement group. Furthermore, all patients were assessed using the Ashworth and modified Japanese Orthopedic Association scores.</p><p><strong>Results: </strong>The incidences of both MEP/SEP improvement (21.4% vs. 25.0%, p=0.772) and deterioration (21.4% vs. 20.0%, p=0.904) were similar between the en bloc and hybrid laminectomy groups, and no difference in preoperative and postoperative clinical assessments was observed between the two groups (p>0.05). In four patients (4/28, 14.3%) undergoing en bloc laminectomy, MEP amplitudes initially increased after OLF removal but gradually decreased. This delayed MEP reduction did not occur in the hybrid laminectomy group. Furthermore, more patients undergoing en bloc laminectomy had CFL than those undergoing hybrid laminectomy (46.4% vs. 15.0%, p=0.023). In the improvement group, the hybrid laminectomy group exhibited higher MEP improvement rates in the bilateral abductor hallucis than the en bloc laminectomy group (left side: 213.4%±35.9% vs. 152.5%±41.0%, p=0.028; right side: 201.2%±32.0% vs. 145.2%±46.3%, p=0.043).</p><p><strong>Conclusions: </strong>Compared with en bloc laminectomy, hybrid laminectomy may be a safe and effective method for treating multilevel TOLF, potentially reducing intraoperative spinal cord irritation and CFL and causing relatively better functional recovery.</p>","PeriodicalId":8555,"journal":{"name":"Asian Spine Journal","volume":"19 1","pages":"74-84"},"PeriodicalIF":2.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11895116/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143555714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Minimally invasive transforaminal interbody fusion for high-grade spondylolisthesis: a retrospective study analysis of a tailor-made solution.","authors":"Arvind Gopalrao Kulkarni, Priyambada Kumar, Arvind Umarani, Shankargouda Patil, Sunil Chodavadiya","doi":"10.31616/asj.2024.0378","DOIUrl":"10.31616/asj.2024.0378","url":null,"abstract":"<p><strong>Study design: </strong>Retrospective study.</p><p><strong>Purpose: </strong>We investigated cantilever reduction and fusion technique in high-grade spondylolisthesis (HGS) with minimally invasive surgery-transforaminal interbody fusion (MIS-TLIF).</p><p><strong>Overview of literature: </strong>Most publications that describe minimally invasive surgeries for HGS, especially grade 4 or 5 listhesis, utilized a combined anterior and posterior approach. To the best of our knowledge, a detailed report that provides specific technical nuances for optimal use of a posterior-only approach utilizing MIS-TLIF is greatly lacking.</p><p><strong>Methods: </strong>This study included 36 patients with HGS in whom reduction, posterior instrumentation, and fusion were achieved with MIS- TLIF. They were evaluated for lower back pain and radicular pain, scaled by Visual Analog Scale (VAS) score. Erect radiographs were performed to calculate slip angle (SA) and sacropelvic and spinopelvic parameters preoperatively, postoperatively, and at each follow-up until 4 years.</p><p><strong>Results: </strong>This study identified 30 patients with grade III HGS and six patients with grade IV/V HGS. Spinopelvic parameters were unbalanced in 13 patients. Complete reduction was achieved in 24 patients, with end-stage reduction of grade I with adequate spinopelvic balance achieved in 12 patients. Intraoperative neuromonitoring demonstrated no loss of signals throughout the procedure in any of the patients. Excellent functional outcome was achieved with back pain as well as leg pain VAS score improvements postoperatively in all patients. No implant-related complications or pseudoarthrosis incidences were reported at long-term follow-up at 4 years.</p><p><strong>Conclusions: </strong>MIS-TLIF for HGS is a specific solution for a complex pathology, enabling one to achieve an excellent clinical as well as radiological outcome.</p>","PeriodicalId":8555,"journal":{"name":"Asian Spine Journal","volume":"19 1","pages":"10-20"},"PeriodicalIF":2.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11895110/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143555784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Functional outcomes of microdiscectomy in Bertolotti syndrome: the relationship between lumbosacral transitional vertebrae and lumbar disc herniation: a prospective study in Greece.","authors":"Stylianos Kapetanakis, Krikor Gkoumousian, Nikolaos Gkantsinikoudis, Constantinos Chaniotakis","doi":"10.31616/asj.2024.0213","DOIUrl":"10.31616/asj.2024.0213","url":null,"abstract":"<p><strong>Study design: </strong>The lumbosacral transitional vertebrae (LSTV) in patients with Bertolotti syndrome (BS) cause alterations in the biomechanics of the lumbosacral junction. These entities have been associated with secondary conditions, such as lumbar disc herniation (LDH).</p><p><strong>Purpose: </strong>To investigate the clinical outcomes of microdiscectomy in patients with symptomatic LDH and BS.</p><p><strong>Overview of literature: </strong>There is limited data in the literature on the functional outcomes of patients with LSTV who undergo microdiscectomy.</p><p><strong>Methods: </strong>This study enrolled 308 patients diagnosed with LDH and concurrent LSTV. All patients underwent microdiscectomy. Clinical evaluation was performed preoperatively and at distinct follow-up intervals of 1, 3, 6, and 12 months, and 2 and 5 years postoperatively. Assessment included clinical examination and implementation of the well-established, patient-reported outcome measures Visual Analog Scale (VAS) and Short-Form 36 (SF-36) Medical Health Survey Questionnaire for Health-Related Quality of Life (HRQoL) analysis. Furthermore, the anatomical relationship between LSTV and LDH was also studied.</p><p><strong>Results: </strong>The SF-36 indices and VAS score were statistically significantly ameliorated within the follow-up period. Maximum improvement was noted at 3 months, with further minimal improvement after 6 months, and stabilization of indices until the end of followup. Castellvi type IB was the most frequent LSTV type. The adjacent level (L4-L5) just above the LSTV was the most affected with an incidence of 72.1%. In the subgroups of Castellvi type IA, IIA, and IIIA, the LDH side was ipsilateral with the LSTV in 38.3% of patients. In this study, all patients underwent microdiscectomy and demonstrated favorable clinical outcomes (functional recovery and pain relief) and notable amelioration of HRQoL.</p><p><strong>Conclusions: </strong>To the best of our knowledge, this is the first study to conduct a holistic assessment in an attempt to delineate the impact of LSTV presence on the postoperative HRQoL of these individuals.</p>","PeriodicalId":8555,"journal":{"name":"Asian Spine Journal","volume":"19 1","pages":"94-101"},"PeriodicalIF":2.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11895107/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143555739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}