Asian journal of psychiatry最新文献_第7页

Clinical High-Risk for Psychosis (CHR-P) circa 2024: Synoptic analysis and synthesis of contemporary treatment guidelines 2024 年左右的临床高危精神病 (CHR-P)：当代治疗指南的综合分析和综述

IF 3.8 4区医学

Asian journal of psychiatry Pub Date : 2024-07-22 DOI: 10.1016/j.ajp.2024.104142

{"title":"Clinical High-Risk for Psychosis (CHR-P) circa 2024: Synoptic analysis and synthesis of contemporary treatment guidelines","authors":"","doi":"10.1016/j.ajp.2024.104142","DOIUrl":"10.1016/j.ajp.2024.104142","url":null,"abstract":"<div><p>The construct of Clinical-High Risk for Psychosis (CHR-P) identifies young help-seeking subjects in putative prodromal stages of psychosis and is a central component of the Early Intervention (EI) paradigm in Mental Health, aimed at facilitating rapid entry into appropriate care pathways to prevent the onset of psychosis or mitigate is biopsychosocial consequences. This approach, which promotes an innovative culture of care for early, at risk situations, is inspired by a clinical staging concept as a guide to optimal treatment. The objective of this article is to map the existing guidelines in the field of CHR-P treatment recommendations, examine overlaps and differences, and critically evaluate blind spots to be addressed in future guideline updated. The search identified 9 guidelines focused on CHR-P or schizophrenia and other psychotic conditions but containing a specific section on CHR-P or prodromal psychosis. All guidelines acknowledge that psychosis is preceded by more or less pronounced prodromal stages, and most detail CHR-P criteria. Among guidelines, 8 out of 9 indicate cognitive-behavioural therapy as the best psychotherapeutic option and 7 out of 9 suggest that antipsychotics can be prescribed as second option in case psychosocial and/or other pharmacological interventions prove insufficient or inadequate in reducing clinical severity and subjective suffering. Antidepressants, mood stabilizers, and benzodiazepines were considered for the treatment of comorbid disorders. Only the European Psychiatric Association Guidance paper distinguished treatment recommendations for adults and minors. Agreements in treatment guidelines were discussed in light of recent meta-analytical evidences on pharmacological and non-pharmacological treatments for CHR-P, suggesting the need to provide an updated, age-sensitive consensus on how to manage CHR-P individuals.</p></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1876201824002351/pdfft?md5=221f1d0b5f9b4da95ab3c901ff8a7736&pid=1-s2.0-S1876201824002351-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141844661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Potential effect of ketamine in treatment for dextromethorphan use disorder exploding in Japanese young population 氯胺酮在治疗日本年轻人中出现的右美沙芬使用障碍方面的潜在效果。

IF 3.8 4区医学

Asian journal of psychiatry Pub Date : 2024-07-21 DOI: 10.1016/j.ajp.2024.104164

引用次数: 0

Cognitive impairment in patients with history of severe COVID 有严重 COVID 病史患者的认知障碍

IF 3.8 4区医学

Asian journal of psychiatry Pub Date : 2024-07-21 DOI: 10.1016/j.ajp.2024.104163

引用次数: 0

Autism spectrum disorder, social pragmatic communication disorder, developmental language disorder- multimorbidity or mutual exclusivity? 自闭症谱系障碍、社交语用沟通障碍、发育性语言障碍--多病共存还是互为因果？

IF 3.8 4区医学

Asian journal of psychiatry Pub Date : 2024-07-17 DOI: 10.1016/j.ajp.2024.104162

引用次数: 0

The Gaza conflict and the role of psychiatry: A call to action 加沙冲突与精神病学的作用：行动呼吁

IF 3.8 4区医学

Asian journal of psychiatry Pub Date : 2024-07-17 DOI: 10.1016/j.ajp.2024.104160

引用次数: 0

Public Mental Health: What role must and can a psychiatrist play 公共心理健康：精神科医生必须和能够发挥什么作用

IF 3.8 4区医学

Asian journal of psychiatry Pub Date : 2024-07-17 DOI: 10.1016/j.ajp.2024.104161

引用次数: 0

Treatment-emergent symptoms during short-term ketamine administration in treatment-resistant bipolar depression: A retrospective cross-sectional descriptive study 短期使用氯胺酮治疗耐药双相抑郁症期间出现的突发症状：一项回顾性横断面描述性研究

IF 3.8 4区医学

Asian journal of psychiatry Pub Date : 2024-07-15 DOI: 10.1016/j.ajp.2024.104159

{"title":"Treatment-emergent symptoms during short-term ketamine administration in treatment-resistant bipolar depression: A retrospective cross-sectional descriptive study","authors":"","doi":"10.1016/j.ajp.2024.104159","DOIUrl":"10.1016/j.ajp.2024.104159","url":null,"abstract":"<div><p>Symptoms that emerge during pharmacological treatment of bipolar depression are frequently observed, underscoring the necessity for comprehensive treatment monitoring. This observational study sought to observe the correlation of eight intravenous ketamine infusions with treatment-emergent depressive symptoms in treatment-resistant bipolar depression patients who maintained their baseline psychotropic and chronic somatic treatments. Depressive symptoms were evaluated using the Inventory of Depressive Symptomatology Self-Report 30 (IDS-SR30). Treatment-emergent symptoms TES were defined as symptoms absent at baseline but present at the conclusion of the study. The most common TES included decreased appetite, increased weight, hypersomnia, and diurnal mood variation. Conversely, feelings of sadness, altered perceptions of the future, decreased interest in sex, and physical discomfort were absent in all patients. Notably, 13.6 % of patients reported thoughts of death or suicide. Larger-scale studies, integrating clinician-rated and patient-reported outcome measures, are essential to deepen our understanding of treatment-emergent symptoms. Establishing regulatory or professional definitions for treatment-emergent symptoms is warranted to improve the robustness of future research endeavors.</p></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141630897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effect of bright light therapy on major depressive disorder: A systematic review and meta-analysis of randomised controlled trials 强光疗法对重度抑郁症的影响：随机对照试验的系统回顾和荟萃分析

IF 3.8 4区医学

Asian journal of psychiatry Pub Date : 2024-07-15 DOI: 10.1016/j.ajp.2024.104149

{"title":"The effect of bright light therapy on major depressive disorder: A systematic review and meta-analysis of randomised controlled trials","authors":"","doi":"10.1016/j.ajp.2024.104149","DOIUrl":"10.1016/j.ajp.2024.104149","url":null,"abstract":"<div><h3>Background</h3><p>The increasing prevalence of major depressive disorder (MDD) has led to increased demand for psychotherapy and pharmacotherapy, yet concerns were raised regarding the cost and accessibility to these therapies. Bright light therapy (BLT) has shown promise in mitigating depressive symptoms of non-seasonal affective disorders. This meta-analysis gathered evidence from randomised controlled trials (RCTs) to assess the effectiveness of BLT on patients with non-seasonal MDD.</p></div><div><h3>Methods</h3><p>Five databases were systematically searched. The primary outcome of the meta-analysis was the endpoint depression score from the BLT and control treatment groups, with the remission and response rates as the secondary outcomes. Results are presented in standardised mean difference (SMD) and log odd ratio. Subgroup analyses compared the effects of trial length and the length of daily exposure.</p></div><div><h3>Results</h3><p>Results on 15 RCTs between 1996 and 2024 with 883 patients showed positive effects of BLT on alleviating depressive symptoms (<em>SMD</em> = 0.48, 95 % <em>CI</em> [0.22, 0.74], <em>p <</em>.001). Trials that lasted two weeks or less or those with 60 minutes or more of daily exposure were associated with higher therapeutic effectiveness. BLT was also associated with a higher response rate at the end of the trial.</p></div><div><h3>Conclusion</h3><p>This meta-analysis offers positive evidence that favours BLT in alleviating depressive symptoms in MDD, suggesting that it could be a convenient and easily accessible treatment modality to augment psychotherapy and pharmacotherapy.</p></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141706986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Repetition-Dependent Adaptation and Prediction Error Signalling in Schizophrenia Patients With Auditory Hallucinations: A Roving Mismatch Negativity Study 患有听觉幻觉的精神分裂症患者的重复依赖性适应和预测错误信号：巡回错配负性研究

IF 3.8 4区医学

Asian journal of psychiatry Pub Date : 2024-07-14 DOI: 10.1016/j.ajp.2024.104158

{"title":"Repetition-Dependent Adaptation and Prediction Error Signalling in Schizophrenia Patients With Auditory Hallucinations: A Roving Mismatch Negativity Study","authors":"","doi":"10.1016/j.ajp.2024.104158","DOIUrl":"10.1016/j.ajp.2024.104158","url":null,"abstract":"<div><h3>Background</h3><p>Dysregulated prediction error-signalling may explain auditory hallucinations in schizophrenia (SZ-AH). Roving mismatch negativity (rMMN) is an event-related potential (ERP) index where the deviant tone becomes the new standard with repetitions. Longer repetitions of standard stimuli yield a more positive sensory-adaptation response (Repetition Positivity–RP), elicit a stronger deviance-detection when interrupted (deviant negativity–DN), and the difference waveform between them reflects the strength of prediction-error signalling (mismatch negativity–MMN).</p></div><div><h3>Methods</h3><p>Twenty-three SZ-AH patients and twenty-three healthy controls (HC) underwent rMMN assessment. Various standard stimuli were repeated in sets of 3, 8 and 33 yielding three components for RP (RP3, RP8, RP33), DN (DN3, DN8, DN33), and MMN (MMN3, MMN8, MMN33). Amplitudes and latencies were compared across groups. Correlation between (a) rMMN amplitudes and latencies, and clinical variables in SZ-AH, and (b) the RP-DN amplitude pair for all three repetition sets (3, 8, 33) were also examined.</p></div><div><h3>Results</h3><p>All DN and MMN33 amplitudes were significantly suppressed in SZ-AH, while RP amplitudes were not. MMN33 latency was significantly longer in SZ-AH than HC. A few amplitudes and latencies significantly correlated with the frequency of AH. HC showed a significant positive correlation between RP-DN amplitude pairs for sets of 3 and 8 but not for 33; SZ-AH group’s correlation profile was opposite to this.</p></div><div><h3>Discussion</h3><p>The link between repetition-dependent sensory-adaptation and deviance-detection is perturbed in SZ-AH. The unimpaired RP profile in SZ-AH is due to potential interference of AH with auditory information processing, and does not indicate a preserved short-term plasticity of the echoic memory trace.</p></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141728911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Home-based tDCS for schizophrenia: Exploring the feasibility of a standard operating procedure 基于家庭的 tDCS 治疗精神分裂症：探索标准操作程序的可行性

IF 3.8 4区医学

Asian journal of psychiatry Pub Date : 2024-07-14 DOI: 10.1016/j.ajp.2024.104150

{"title":"Home-based tDCS for schizophrenia: Exploring the feasibility of a standard operating procedure","authors":"","doi":"10.1016/j.ajp.2024.104150","DOIUrl":"10.1016/j.ajp.2024.104150","url":null,"abstract":"<div><p>Transcranial Direct Current Stimulation (tDCS), a safe and easy-to-administer noninvasive brain stimulation technique, holds promise in managing auditory verbal hallucinations (AVH) in schizophrenia. However, its short-lasting effect often leads to frequent hospital visits for booster/maintenance sessions, posing logistical challenges. Home-based tDCS offers a potential solution that improves accessibility; however, careful standardisation is required to ensure safe and effective application. We present a case of schizophrenia, where add-on home-based tDCS was administered based on a standard operating procedure (SOP) developed to address challenges unique to home administration, like device-related factors, patient and caregiver-related factors, and comprehensive caregiver training protocol. As a part of training, caregivers underwent observational learning, mannequin-based training for electrode placement, and assisted live-patient sessions. Pre and post-training competency assessments were done to ensure proficiency and safe administration. Over ten days, home-based tDCS sustained improvements in AVH without adverse effects. This case report supports the feasibility of home-based tDCS and provides a detailed SOP for implementing a safe and effective home-based tDCS treatment regime. This comprehensive SOP with a training protocol is notedly efficient for enhancing the accessibility and affordability of tDCS treatment protocols.</p></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141690870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0