Asian journal of psychiatry最新文献

{"title":"Affective temperaments: Effects on treatment response for major depression","authors":"Ross J. Baldessarini ,&nbsp;Alessandro Miola ,&nbsp;Leonardo Tondo","doi":"10.1016/j.ajp.2024.104335","DOIUrl":"10.1016/j.ajp.2024.104335","url":null,"abstract":"<div><div>There is growing interest in assessing affective temperaments in relation to major depressive disorder (MDD) and bipolar disorder (BD). Needed is evaluation of the impact of temperament ratings on responses to treatment of depression in these disorders. We measured treatment response as %-improvement in HDRS₂₁ depression ratings and correlated this measure as well as response rate (≥50 % improvement) with TEMPS-A ratings of anxious, cyclothymic, dysthymic, hyperthymic, and irritable affective temperaments in 2264 mood-disorder patients (1165 BD, 1099 MDD; 62.3 % women, mean age 48.5 years). Higher dysthymic temperament score was associated with less improvement in depression ratings, greater hyperthymia scores with increased improvement. Both temperaments also were associated with increases (dysthymia) or decreases (hyperthymia) in initial HDRS₂₁ scores. However, higher initial HDRS₂₁ scores led to <em>greater</em> percent-improvement. Multivariable logistic regression sustained independent effects of temperament scores on treatment-response. Reported effects were similar with MDD and BD. Limitations include the observational design limiting causality and uncertain generalizability to other geographical locations or clinical settings. Ratings of dysthymic and hyperthymic temperaments, respectively, were associated with significantly lesser and greater improvement of depression ratings with both MDD and BD.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"103 ","pages":"Article 104335"},"PeriodicalIF":3.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142812056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative effectiveness of interventions for the prevention and treatment of perinatal depression: A systematic review and network meta-analysis","authors":"Robert David Smith ,&nbsp;Wen Dang ,&nbsp;Shuyuan Shen ,&nbsp;Sze Chai Hung ,&nbsp;Ip Hoi Lam ,&nbsp;Jojo Y.Y. Kwok ,&nbsp;Edmond P.H. Choi ,&nbsp;Daniel Y.T. Fong ,&nbsp;Shehzad Ali ,&nbsp;Claire A. Wilson ,&nbsp;Kris Y.W. Lok","doi":"10.1016/j.ajp.2024.104316","DOIUrl":"10.1016/j.ajp.2024.104316","url":null,"abstract":"<div><h3>Background</h3><div>Several interventions have been investigated addressing perinatal depression; however, interventions have not been compared using both direct and indirect evidence. This study compared the relative effectiveness of all interventions that prevent depression (objective 1) or treat depression symptoms (objective 2) in perinatal women.</div></div><div><h3>Methods</h3><div>Eight databases searched from their inception to March 2024. Inclusion criteria were randomised controlled trials in perinatal women participants evaluating any interventions that addressed prevention or treatment of depression. Two random-effects Bayesian network meta-analyses were conducted using studies with perinatal women participants reporting frequency of depression or reporting depression severity. For objective 1 odds ratios (OR) and objective 2 standardised mean differences (SMD) were used.</div></div><div><h3>Results</h3><div>A total of 177 articles were included (n = 76 objective 1, n = 101 objective 2). For objective 1; mindfulness was the highest-ranking intervention (SCURA=88), with significant OR compared to treatment as usual (TAU) (OR=0.21; 0.06, 0.71 95 %CrI). Other interventions with significant OR, compared to TAU included: pharmacological treatments, CBT, physical activities, education, and collaborative care. For objective 2; interpersonal therapy plus massage was the highest-ranking intervention (SCURA=89) with significant SMD compared to TAU (SMD=-1.38; −2.54, −0.21). Other interventions with significant SMD compared to TAU: IPT, alternative therapies, physical activities, mindfulness, CBT, collaborative care, education, and enhanced TAU. Pharmacological treatments were effective compared to sham/placebo.</div></div><div><h3>Conclusion</h3><div>CBT, mindfulness, physical activity, collaborative care, education, and pharmacological interventions were effective in addressing prevention and treatment of perinatal depression symptoms compared to control arms. Healthcare providers may consider offering these interventions to perinatal women.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"103 ","pages":"Article 104316"},"PeriodicalIF":3.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142852359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implementing a collaborative care model for child and adolescent mental health in Qatar: Addressing workforce and access challenges","authors":"Mohamed Adil Shah Khoodoruth ,&nbsp;Muhammad Abdur Rahman Khoodoruth ,&nbsp;Widaad Nuzhah Chut-Kai Khoodoruth","doi":"10.1016/j.ajp.2024.104347","DOIUrl":"10.1016/j.ajp.2024.104347","url":null,"abstract":"<div><div>Child and adolescent mental health disorders in Qatar remain significantly underserved due to a critical shortage of specialists, stigma, and logistical barriers. This paper proposes implementing a Collaborative Care Model (CoCM) within Qatar’s primary care settings, leveraging existing infrastructure, such as the CERNER electronic health record system, and innovations like telepsychiatry and AI-driven tools. The model integrates task-sharing among interdisciplinary teams to enhance accessibility and continuity of care. This commentary explores the model’s feasibility, addressing challenges like workforce shortages and psychotropic prescribing processes. The proposed CoCM offers a sustainable solution to improve youth mental health outcomes and reduce systemic disparities.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"103 ","pages":"Article 104347"},"PeriodicalIF":3.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142891517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety and efficacy of early augmentation with Transcranial Direct Current Stimulation (tDCS) in adolescents with Major Depressive Disorder: A randomized controlled trial","authors":"Saumya Upadhyay,&nbsp;Vivek Agarwal,&nbsp;Amit Arya,&nbsp;Sujita Kumar Kar","doi":"10.1016/j.ajp.2024.104349","DOIUrl":"10.1016/j.ajp.2024.104349","url":null,"abstract":"<div><h3>Background</h3><div>Transcranial Direct Current Stimulation (tDCS) is an emerging modality with demonstrated efficacy in Major Depressive Disorder (MDD), however, there is paucity of research in adolescent depression. This study attempts to evaluate the safety and efficacy of tDCS in adolescents with MDD as an early augmentation to drug therapy.</div></div><div><h3>Methods</h3><div>Adolescents with MDD aged 10–18 years were enrolled in the study and allocated to active or sham groups as per randomization. Sertraline was given in the range of 25–50 mg to each participant. After baseline assessments, 10 sessions of tDCS were given with 2 mA current for 20 minutes, keeping anode at left DLPFC and cathode at right DLPFC. Side effects were assessed and rating scales were reapplied at 2 weeks and then 6 weeks. Results were analyzed.</div></div><div><h3>Results</h3><div>A total of 32 patients were analysed (15-active, 17-sham). At 2 weeks, the BDI and BAI scores of the true group were significantly lower than the sham group, and the reduction in the scores of the former was statistically greater. This significance did not persist at 6 weeks, and the reduction in the scores of the two groups was significantly different from baseline to 2-weeks and 6-weeks. Response and remission rates were higher in the active group at 6 weeks. Adverse effects were comparable.</div></div><div><h3>Conclusion</h3><div>tDCS is safe and effective for early augmentation of drugs in adolescents with MDD. However, effects do not last long after termination of sessions. Further studies are needed with a larger sample size and longer follow-ups.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"103 ","pages":"Article 104349"},"PeriodicalIF":3.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142902547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improving acceptance of psychosis risk terminology through cultural sensitivity","authors":"Isnaria Rizki Hayati,&nbsp;Elni Yakub,&nbsp;Rikas Saputra ,&nbsp;Yenni Lidyawati,&nbsp;Rizky Andana Pohan,&nbsp;Erfan Ramadhani","doi":"10.1016/j.ajp.2024.104352","DOIUrl":"10.1016/j.ajp.2024.104352","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"103 ","pages":"Article 104352"},"PeriodicalIF":3.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142909173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Digital mental health interventions in India: Addressing challenges and expanding access","authors":"Sonia Mathew,&nbsp;Ajay Jose,&nbsp;Rejikumar G","doi":"10.1016/j.ajp.2024.104339","DOIUrl":"10.1016/j.ajp.2024.104339","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"103 ","pages":"Article 104339"},"PeriodicalIF":3.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142812095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Care provider's experiences on working with homeless persons with mental illness in institutions: A qualitative study","authors":"Roniyamol Roy ,&nbsp;K. Janaki Raman ,&nbsp;E. Aravind Raj ,&nbsp;Shivarama Varambally","doi":"10.1016/j.ajp.2024.104343","DOIUrl":"10.1016/j.ajp.2024.104343","url":null,"abstract":"<div><h3>Introduction</h3><div>Homelessness embodies a prevalent societal issue that results in extensive socio-economic ramifications. Residential rehabilitation establishments, including shelters and mental health facilities, offer essential assistance to individuals with insecure housing situations. The healthcare providers within these facilities struggle to effectively tackle the underlying issues faced by homeless individuals, often due to a variety of socio-economic factors.</div></div><div><h3>Aims</h3><div>The study evaluates the mental health knowledge, practices, attitudes, and training needs of the care providers in the rehabilitation centres for homeless persons with mental illness.</div></div><div><h3>Methods</h3><div>A qualitative exploratory research design using FGDs with care providers and expert interviews. Purposive sampling has been used to recruit care providers and experts. Thematic analysis was used to analyse the data obtained.</div></div><div><h3>Results</h3><div>The major themes emerged out of thematic analysis were characteristics and needs of the homeless persons with mental illness admitted to the institution, concerns of care providers on the services they offer, barriers and challenges in healthcare extended in institutions, diverse rehabilitation needs of the homeless population, training needs of the care providers including mental health knowledge, preparedness to work with homeless population, managing support needs of the homeless population, and the skills in empowering the homeless persons with mental illness.</div></div><div><h3>Conclusion</h3><div>The findings emphasize the importance of proficient healthcare providers in aiding and enhancing the rehabilitation of homeless individuals suffering from mental disorders within institutional settings. There is an urgent need to strengthen the economic and social resources in institutions to create a more inclusive environment for the homeless population.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"103 ","pages":"Article 104343"},"PeriodicalIF":3.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142891515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of mummies on modern psychiatry","authors":"Khaled Elbarbary,&nbsp;Sheikh Shoib,&nbsp;Miyuru Chandradasa,&nbsp;Fahimeh Saeed","doi":"10.1016/j.ajp.2024.104342","DOIUrl":"10.1016/j.ajp.2024.104342","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"103 ","pages":"Article 104342"},"PeriodicalIF":3.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142871206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Magnetic seizure therapy versus electroconvulsive therapy for major mental disorders: A systematic review","authors":"Zhan-Ming Shi ,&nbsp;Zhi-Ang Su ,&nbsp;Ting Ning ,&nbsp;Wei Zheng","doi":"10.1016/j.ajp.2024.104336","DOIUrl":"10.1016/j.ajp.2024.104336","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"103 ","pages":"Article 104336"},"PeriodicalIF":3.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142845712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Autistic symptoms and clinical features of individuals at clinical high risk for psychosis and first-episode psychosis","authors":"Hiroshi Komatsu ,&nbsp;Yutaro Sato ,&nbsp;Kazuho Tomimoto ,&nbsp;Goh Onoguchi ,&nbsp;Tasuku Matsuki ,&nbsp;Yumiko Hamaie ,&nbsp;Atsushi Sakuma ,&nbsp;Noriyuki Ohmuro ,&nbsp;Masahiro Katsura ,&nbsp;Fumiaki Ito ,&nbsp;Takashi Ono ,&nbsp;Kazunori Matsumoto ,&nbsp;Hiroaki Tomita","doi":"10.1016/j.ajp.2024.104345","DOIUrl":"10.1016/j.ajp.2024.104345","url":null,"abstract":"<div><h3>Introduction</h3><div>Autistic symptoms in schizophrenia are reportedly associated with cognitive and social functions. However, few studies have investigated the association between autistic symptoms and clinical features in individuals with a clinical high risk for psychosis (CHR-P) and first-episode psychosis (FEP). We aimed to determine the association between autistic symptoms and clinical features in a cohort of individuals with CHR-P or FEP.</div></div><div><h3>Methods</h3><div>This cross-sectional study included 111 participants (CHR-P: 61, FEP: 50). Autistic symptoms were assessed using the Positive and Negative Syndrome Scale for Schizophrenia Autism Severity Scale. We assessed the association between autistic symptoms and global and social functioning, and cognitive function in individuals with CHR-P or EFP. Multiple regression analysis was also performed using age and sex as covariates to determine the association between autistic symptoms and global functioning.</div></div><div><h3>Results</h3><div>The participants with FEP had more severe autistic symptoms than those with CHR-P. The results of bivariate correlation analysis showed a significantly negative association of autistic symptoms with global and cognitive functions in both participants with CHR-P and those with FEP. Multiple regression analysis showed that sex, autistic symptoms, and positive symptoms were significant predictors of overall functioning in those participants.</div></div><div><h3>Conclusion</h3><div>These findings suggest that autistic symptoms are associated with lower global functioning with both individuals at CHR-P and those with FEP. Further longitudinal analysis is needed to characterize the association between autistic symptoms and global functioning in CHR-P and FEP.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"103 ","pages":"Article 104345"},"PeriodicalIF":3.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142885217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}