Asian journal of psychiatry最新文献

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Health literacy and the continuum of suicidal behaviors among adults: A national survey from South Korea, 2023 健康素养和成年人自杀行为的连续性:韩国2023年的一项全国性调查。
IF 4.5 4区 医学
Asian journal of psychiatry Pub Date : 2026-03-01 Epub Date: 2026-02-02 DOI: 10.1016/j.ajp.2026.104884
Seong-Uk Baek, Jin-Ha Yoon
{"title":"Health literacy and the continuum of suicidal behaviors among adults: A national survey from South Korea, 2023","authors":"Seong-Uk Baek, Jin-Ha Yoon","doi":"10.1016/j.ajp.2026.104884","DOIUrl":"10.1016/j.ajp.2026.104884","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"117 ","pages":"Article 104884"},"PeriodicalIF":4.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146123680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advancing psychotherapy in Malaysian psychiatric practice: The role of the psychotherapy chapter of the Malaysian Psychiatric Association 在马来西亚精神病实践中推进心理治疗:马来西亚精神病协会心理治疗分会的作用。
IF 4.5 4区 医学
Asian journal of psychiatry Pub Date : 2026-03-01 Epub Date: 2026-02-02 DOI: 10.1016/j.ajp.2026.104877
Chong Seng Choi, Nik Ruzyanei Nik Jaafar
{"title":"Advancing psychotherapy in Malaysian psychiatric practice: The role of the psychotherapy chapter of the Malaysian Psychiatric Association","authors":"Chong Seng Choi, Nik Ruzyanei Nik Jaafar","doi":"10.1016/j.ajp.2026.104877","DOIUrl":"10.1016/j.ajp.2026.104877","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"117 ","pages":"Article 104877"},"PeriodicalIF":4.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146131126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PrecInNor: An Indo-Norway collaborative programme for precision psychiatry training PrecInNor:印度-挪威精确精神病学培训合作项目。
IF 4.5 4区 医学
Asian journal of psychiatry Pub Date : 2026-03-01 Epub Date: 2026-01-10 DOI: 10.1016/j.ajp.2026.104852
Satish Suhas, Pravesh Parekh, Vanteemar S Sreeraj, Biju Viswanath, Srdjan Djurovic, Oleksandr Frei, Alexey A. Shadrin, Olav Bjerkehagen Smeland, Torill Ueland, Christine Lycke Brandt, Elisabeth Strand Vigtel, Reeteka Sud, Meera Purushottam, Ajay Kumar, M. Manjula, Anita Mahadevan, Ganesan Venkatasubramanian, Paulomi Matam Sudhir, John P. John, Ole A. Andreassen
{"title":"PrecInNor: An Indo-Norway collaborative programme for precision psychiatry training","authors":"Satish Suhas, Pravesh Parekh, Vanteemar S Sreeraj, Biju Viswanath, Srdjan Djurovic, Oleksandr Frei, Alexey A. Shadrin, Olav Bjerkehagen Smeland, Torill Ueland, Christine Lycke Brandt, Elisabeth Strand Vigtel, Reeteka Sud, Meera Purushottam, Ajay Kumar, M. Manjula, Anita Mahadevan, Ganesan Venkatasubramanian, Paulomi Matam Sudhir, John P. John, Ole A. Andreassen","doi":"10.1016/j.ajp.2026.104852","DOIUrl":"10.1016/j.ajp.2026.104852","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"117 ","pages":"Article 104852"},"PeriodicalIF":4.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146008665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Climate change and mental health: A multinational study of climate-anxiety, coping, and psychosocial responses 气候变化与心理健康:气候焦虑、应对和心理社会反应的多国研究
IF 4.5 4区 医学
Asian journal of psychiatry Pub Date : 2026-03-01 Epub Date: 2026-01-20 DOI: 10.1016/j.ajp.2026.104859
Julio Torales , Iván Barrios , Antonio Ventriglio , João Mauricio Castaldelli-Maia , Myrna Lashley , Mike Campbell , Michael Liebrenz , Padmavati Ramachandran , Neil Krishan Aggarwal , Rowalt Alibudbud , Egor Chumakov , Joana Corrêa de Magalhães Narvaez , Afzal Javed , Dinesh Bhugra , Albert Persaud , on behalf of the World Psychiatric Association Special Interest Group on Geopsychiatry
{"title":"Climate change and mental health: A multinational study of climate-anxiety, coping, and psychosocial responses","authors":"Julio Torales ,&nbsp;Iván Barrios ,&nbsp;Antonio Ventriglio ,&nbsp;João Mauricio Castaldelli-Maia ,&nbsp;Myrna Lashley ,&nbsp;Mike Campbell ,&nbsp;Michael Liebrenz ,&nbsp;Padmavati Ramachandran ,&nbsp;Neil Krishan Aggarwal ,&nbsp;Rowalt Alibudbud ,&nbsp;Egor Chumakov ,&nbsp;Joana Corrêa de Magalhães Narvaez ,&nbsp;Afzal Javed ,&nbsp;Dinesh Bhugra ,&nbsp;Albert Persaud ,&nbsp;on behalf of the World Psychiatric Association Special Interest Group on Geopsychiatry","doi":"10.1016/j.ajp.2026.104859","DOIUrl":"10.1016/j.ajp.2026.104859","url":null,"abstract":"<div><h3>Background</h3><div>Climate change is an increasingly important determinant of global mental health, affecting emotional, cognitive, behavioral, and social functioning. The emergence of climate-anxiety and the unequal distribution of environmental risks highlight the need for cross-cultural evidence to inform equitable adaptation strategies.</div></div><div><h3>Aim</h3><div>To examine the psychological and functional impacts of climate change across diverse populations, focusing on climate-anxiety, emotional responses, coping strategies, and perceived psychosocial support within a geopsychiatry framework.</div></div><div><h3>Methods</h3><div>A multinational cross-sectional survey was conducted among 388 adults from 44 countries using the Hogg Climate Anxiety Scale (HCAS) and additional items on climate-related experiences, functional disruption, coping strategies, and access to essential resources. Data were analyzed using descriptive statistics, non-parametric tests, multiple linear regression, and thematic analysis of open-ended responses.</div></div><div><h3>Results</h3><div>Overall, 83.5 % of participants reported exposure to at least one extreme climate event in the past five years, most commonly heatwaves, floods, and severe storms. Climate anxiety differed by gender in affective symptoms, rumination, and personal impact anxiety (Kruskal–Wallis, p ≤ .007). Participants exposed to extreme events reported higher affective (p = .017), behavioral (p = .001), and personal impact anxiety (p = .045). The regression model explained 25 % of the variance in total HCAS scores (R² = 0.25, p &lt; .001), with climate-related functional disruption as the strongest predictor.</div></div><div><h3>Conclusions</h3><div>Climate change is associated with substantial emotional and functional burden, particularly among vulnerable groups. Findings support integrating mental health screening and brief psychosocial interventions into climate adaptation policies, primary care, and community-based resilience programs.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"117 ","pages":"Article 104859"},"PeriodicalIF":4.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146024140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perspectives on psychotherapy in Southeast Asia: Insights from psychiatrists and trainees (Part II: Barriers to access and future directions) 东南亚心理治疗的观点:来自精神科医生和学员的见解(第二部分:获取障碍和未来方向)
IF 4.5 4区 医学
Asian journal of psychiatry Pub Date : 2026-03-01 Epub Date: 2026-01-25 DOI: 10.1016/j.ajp.2026.104873
Warut Aunjitsakul , Kanthee Anantapong , Nisan Werachattawan , Kreuwan Jongbovonwiwat , Rasmon Kalayasiri , Daruj Aniwattanapong , Poom Chompoosri , Andre Teck Sng Tay , Samuel Eng Teck Cheng , Sanjiv Sasidharan Nair , David Choon Liang Teo , Petrin Redayani Lukman , Sylvia Detri Elvira , Alfi Fajar Almasyhur , Nik Ruzyanei Nik Jaafar , Farah Nabila binti Abd Majid , Jiann Lin Loo , Nuur Asyikin binti Mohd Shukor , Eric Bui , Thi Tuong Vi Vu , César A. Alfonso
{"title":"Perspectives on psychotherapy in Southeast Asia: Insights from psychiatrists and trainees (Part II: Barriers to access and future directions)","authors":"Warut Aunjitsakul ,&nbsp;Kanthee Anantapong ,&nbsp;Nisan Werachattawan ,&nbsp;Kreuwan Jongbovonwiwat ,&nbsp;Rasmon Kalayasiri ,&nbsp;Daruj Aniwattanapong ,&nbsp;Poom Chompoosri ,&nbsp;Andre Teck Sng Tay ,&nbsp;Samuel Eng Teck Cheng ,&nbsp;Sanjiv Sasidharan Nair ,&nbsp;David Choon Liang Teo ,&nbsp;Petrin Redayani Lukman ,&nbsp;Sylvia Detri Elvira ,&nbsp;Alfi Fajar Almasyhur ,&nbsp;Nik Ruzyanei Nik Jaafar ,&nbsp;Farah Nabila binti Abd Majid ,&nbsp;Jiann Lin Loo ,&nbsp;Nuur Asyikin binti Mohd Shukor ,&nbsp;Eric Bui ,&nbsp;Thi Tuong Vi Vu ,&nbsp;César A. Alfonso","doi":"10.1016/j.ajp.2026.104873","DOIUrl":"10.1016/j.ajp.2026.104873","url":null,"abstract":"<div><h3>Background</h3><div>Psychotherapy's integration into Southeast Asia (SEA) clinical practice is limited despite its recognized effectiveness. This study examined psychiatrists’ and psychiatry trainees’ perspectives on barriers to accessing psychotherapy, expectations for its future delivery, and attitudes toward digital mental health.</div></div><div><h3>Methods</h3><div>A cross-national survey was conducted between March and August 2024 among 253 psychiatrists and psychiatry trainees from Indonesia (n = 121), Malaysia (n = 39), Singapore (n = 6), Thailand (n = 74), and Vietnam (n = 13). The questionnaire explored perspectives on delivering psychotherapy including barriers, provider roles, therapy formats, and digital delivery. Data were analyzed descriptively and comparatively.</div></div><div><h3>Results</h3><div>Key barriers to delivering psychotherapy included time constraints, cost concerns, systemic limitations, and insufficient psychotherapy skills, respectively. Regarding preferences for psychotherapy providers, trainees rated psychiatrists as most suitable, while psychiatrists preferred psychologists. Crisis intervention and individual therapy were the top priorities for training. Although videoconferencing and mobile apps were favored for future delivery, concerns about clinical effectiveness and system-level limitations hindered wider acceptance of digital psychotherapy.</div></div><div><h3>Conclusion</h3><div>A major barrier was that psychotherapy is too time-consuming, and a lack of skills was a significant challenge for healthcare professionals. Both psychiatrists and trainees agreed that training should prioritize crisis intervention and individual therapy. For internet-based psychotherapy, the primary challenge was concern over its low clinical effectiveness, as many felt face-to-face interaction was necessary. The findings highlight the need for enhanced psychotherapy training, systemic support, and digital infrastructure to improve psychotherapy accessibility in SEA. These insights can inform the development of targeted interventions and policies to promote the effective integration of psychotherapy into mental health services in the region.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"117 ","pages":"Article 104873"},"PeriodicalIF":4.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146074672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ten sessions, faster response, or faster exit? Clarifying “Speed” and cost claims in piTBS vs 10-Hz rTMS 十个会话,更快的响应,还是更快的退出?澄清piTBS和10hz rTMS的“速度”和成本要求。
IF 4.5 4区 医学
Asian journal of psychiatry Pub Date : 2026-03-01 Epub Date: 2026-02-02 DOI: 10.1016/j.ajp.2026.104881
Xiaowei Zhang
{"title":"Ten sessions, faster response, or faster exit? Clarifying “Speed” and cost claims in piTBS vs 10-Hz rTMS","authors":"Xiaowei Zhang","doi":"10.1016/j.ajp.2026.104881","DOIUrl":"10.1016/j.ajp.2026.104881","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"117 ","pages":"Article 104881"},"PeriodicalIF":4.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146131111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impaired task-switching in major depressive disorder: A time-frequency analysis of non-emotional and emotional stimuli 重度抑郁症的任务转换受损:非情绪和情绪刺激的时频分析。
IF 4.5 4区 医学
Asian journal of psychiatry Pub Date : 2026-03-01 Epub Date: 2026-02-02 DOI: 10.1016/j.ajp.2026.104879
Kaili Zheng , Wanrong Peng , Zhaoxia Liu , Xiaoshuang Gu , Meiqian Tang , Weijun Situ , Jinyao Yi
{"title":"Impaired task-switching in major depressive disorder: A time-frequency analysis of non-emotional and emotional stimuli","authors":"Kaili Zheng ,&nbsp;Wanrong Peng ,&nbsp;Zhaoxia Liu ,&nbsp;Xiaoshuang Gu ,&nbsp;Meiqian Tang ,&nbsp;Weijun Situ ,&nbsp;Jinyao Yi","doi":"10.1016/j.ajp.2026.104879","DOIUrl":"10.1016/j.ajp.2026.104879","url":null,"abstract":"<div><h3>Background</h3><div>Major depressive disorder (MDD) is characterized by significant impairments in cognitive functions, including task-switching dysfunction. This study investigates the differences in switching impairments between non-emotional and emotional switching tasks in MDD patients and explores the underlying neuropsychological mechanisms.</div></div><div><h3>Methods</h3><div>48 MDD patients and 52 healthy controls (HCs) were recruited. Behavioral and electroencephalogram data were recorded while participants performed non-emotional and emotional task-switching paradigms. Event-related potentials (ERPs: P2, N2, P3 difference waves) and event-related spectral perturbations (ERSPs: theta, alpha, beta band power) were analyzed to assess group differences.</div></div><div><h3>Results</h3><div>In the magnitude task, MDD group displayed reduced occipital Pd2 amplitude (<em>p</em> &lt; 0.001, <em>η</em><sup><em>2</em></sup><sub><em>p</em></sub>=0.20), increased frontal/central Pd3 amplitudes (<em>p</em> &lt; 0.001, <em>η</em><sup><em>2</em></sup><sub><em>p</em></sub>=0.10), and larger alpha power differences (<em>p</em> &lt; 0.05, <em>η</em><sup><em>2</em></sup><sub><em>p</em></sub>= 0.04). In the gender task, MDD group had increased occipital Pd2 amplitude (<em>p</em> &lt; 0.05, <em>η</em><sup><em>2</em></sup><sub><em>p</em></sub>=0.04) and larger al<em>p</em>ha power differences in the P3 time window (<em>p</em> &lt; 0.01, <em>η</em><sup><em>2</em></sup><sub><em>p</em></sub>=0.03). In the emotion task, MDD group showed prolonged Pd2 latency (<em>p</em> &lt; 0.05, <em>η</em><sup><em>2</em></sup><sub><em>p</em></sub>=0.04), reduced Pd3 amplitude (<em>p</em> &lt; 0.05, <em>η</em><sup><em>2</em></sup><sub><em>p</em></sub>=0.10), smaller theta power differences (<em>p</em> = 0.05, <em>η</em><sup><em>2</em></sup><sub><em>p</em></sub>=0.03), and larger beta power differences (<em>p</em> &lt; 0.05, <em>η</em><sup><em>2</em></sup><sub><em>p</em></sub>=0.04).</div></div><div><h3>Conclusion</h3><div>MDD patients exhibit a dissociable pattern of task-switching deficits across non-emotional and emotional task-switching scenarios, characterized by distinct abnormalities across early visual processing, conflict monitoring, cognitive resource allocation, and multi-stage emotional processing. This study reveals novel electrophysiological mechanisms underlying cognitive inflexibility in MDD.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"117 ","pages":"Article 104879"},"PeriodicalIF":4.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146137114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effectiveness of technology-based intervention programs in the prevention of child abuse: A systematic review and meta-analysis study 基于技术的干预方案在预防儿童虐待中的有效性:一项系统回顾和荟萃分析研究。
IF 4.5 4区 医学
Asian journal of psychiatry Pub Date : 2026-03-01 Epub Date: 2026-02-07 DOI: 10.1016/j.ajp.2026.104887
Edanur Tar Bolacali , Gökçe Demir , Bahar Aksoy , Sevda Uzun
{"title":"The effectiveness of technology-based intervention programs in the prevention of child abuse: A systematic review and meta-analysis study","authors":"Edanur Tar Bolacali ,&nbsp;Gökçe Demir ,&nbsp;Bahar Aksoy ,&nbsp;Sevda Uzun","doi":"10.1016/j.ajp.2026.104887","DOIUrl":"10.1016/j.ajp.2026.104887","url":null,"abstract":"<div><div>This study was conducted with the aim of revealing the effectiveness of technology-based intervention programs in the prevention of child abuse. For this systematic review and meta-analysis study, researches were obtained by searching PubMed, Web of Science, Scopus, Google Scholar and National Thesis Center of the Council of Higher Education databases without any year limitation. After the review, 18 studies were included in the study. The data were synthesized by meta-analysis and narrative methods. In this systematic review and meta-analysis, it was found that technology-based intervention programs were effective in preventing child abuse in educators and caregivers (SMD: 0.673; 95% CI: 0.500–1.243; Z = 4.594, p = 0.00, (I<sup>2</sup> = 77.6%). In addition, technology-based intervention programs were found to be effective in preventing child abuse in children SMD: 0.255 95% CI: −0.059 to 0.570; Z = 1.589, p = 0.112, (I<sup>2</sup> = 59.6%) and parents (SMD: 0.194 95% CI: −0.584 to 0.973; Z = 0.490, p = 0.624, (I<sup>2</sup>= 97.6%). This study showed that technology-based intervention programs can play a beneficial and important role on individuals in the prevention of child abuse.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"117 ","pages":"Article 104887"},"PeriodicalIF":4.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146163933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The clue on the bleeding face: Unpacking MiTES (midface toddler excoriation syndrome) through genetics and behaviour 流血的脸上的线索:通过遗传和行为来去除螨虫(脸中部幼儿擦伤综合征)
IF 4.5 4区 医学
Asian journal of psychiatry Pub Date : 2026-03-01 Epub Date: 2026-01-08 DOI: 10.1016/j.ajp.2026.104848
Srivastava Akash , Bhatnagar Priyanka, P.K. Pardal
{"title":"The clue on the bleeding face: Unpacking MiTES (midface toddler excoriation syndrome) through genetics and behaviour","authors":"Srivastava Akash ,&nbsp;Bhatnagar Priyanka,&nbsp;P.K. Pardal","doi":"10.1016/j.ajp.2026.104848","DOIUrl":"10.1016/j.ajp.2026.104848","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"117 ","pages":"Article 104848"},"PeriodicalIF":4.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145975419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute Pisa syndrome in a 4-year-old child with autism spectrum disorder: The youngest reported case of risperidone-induced extrapyramidal reaction 急性比萨综合征的4岁儿童自闭症谱系障碍:最年轻的利培酮诱导锥体外反应的报告病例
IF 4.5 4区 医学
Asian journal of psychiatry Pub Date : 2026-03-01 Epub Date: 2026-01-07 DOI: 10.1016/j.ajp.2026.104838
Himanshu Garg, Abhishek Pandey, Neha Anushree, Shobit Garg , Karthik Ram Mohan
{"title":"Acute Pisa syndrome in a 4-year-old child with autism spectrum disorder: The youngest reported case of risperidone-induced extrapyramidal reaction","authors":"Himanshu Garg,&nbsp;Abhishek Pandey,&nbsp;Neha Anushree,&nbsp;Shobit Garg ,&nbsp;Karthik Ram Mohan","doi":"10.1016/j.ajp.2026.104838","DOIUrl":"10.1016/j.ajp.2026.104838","url":null,"abstract":"<div><h3>Background</h3><div>Pisa syndrome is a rare extrapyramidal disorder characterized by sustained lateral flexion of the trunk, typically associated with antipsychotic medications. Though well-described in adult populations, its occurrence in children is exceedingly rare, with no previously reported cases in children under 12 years of age for drug-induced etiology.</div></div><div><h3>Clinical description</h3><div>We report the case of a 4-year-old boy with autism spectrum disorder (ASD), receiving risperidone (0.5 mL BID) for behavioural issues, on continued behavioural therapy, who developed acute onset painful lateral flexion of the trunk—clinically consistent with Pisa syndrome.</div></div><div><h3>Management &amp; outcome</h3><div>He was promptly treated with intravenous pheniramine maleate, with immediate resolution of symptoms. Risperidone was discontinued, and no recurrence was noted on follow-up. Causality assessment using the Pediatric Naranjo Adverse Drug Reaction Probability Scale yielded a score of 7, indicating a probable adverse drug reaction to risperidone.</div></div><div><h3>Conclusion</h3><div>This case underscores the importance of early recognition of rare extrapyramidal side effects such as Pisa syndrome in children on atypical antipsychotics. Clinicians should maintain a high index of suspicion, even in very young children, and be aware of effective management strategies.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"117 ","pages":"Article 104838"},"PeriodicalIF":4.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145923862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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