Asian Journal of Pharmaceutical Research and Health Care最新文献_第8页

Association of CORADS classification and cardiorespiratory fitness profile among symptomatic and asymptomatic post-coronavirus disease 2019 individuals 2019年冠状病毒感染后症状和无症状个体CORADS分类与心肺健康状况的关系

Asian Journal of Pharmaceutical Research and Health Care Pub Date : 2023-01-01 DOI: 10.4103/ajprhc.ajprhc_35_23

MAnbu Priya, S Hariharan, K Gayathri, JR Abishek

{"title":"Association of CORADS classification and cardiorespiratory fitness profile among symptomatic and asymptomatic post-coronavirus disease 2019 individuals","authors":"MAnbu Priya, S Hariharan, K Gayathri, JR Abishek","doi":"10.4103/ajprhc.ajprhc_35_23","DOIUrl":"https://doi.org/10.4103/ajprhc.ajprhc_35_23","url":null,"abstract":"Background: Physiotherapy treatment is focused for coronavirus disease 2019 (COVID-19) patients in critical, acute, and postacute phases, and the physiotherapists have the responsibility of recovering COVID-19 individuals back to their usual quality of life (QOL). Hence, evaluating the COVID-19 survivor’s QOL is important to improve their independence. Objective: This study aims to assess the patient’s cardiorespiratory fitness in association with their CORADS classification and QOL in post-COVID-19 individuals is essential during this pandemic. Methodology: A retrospective study was conducted with 60 post-COVID-19 individuals who were recruited by convenience. Result: P value of symptomatic and asymptomatic is 0.001, which is considered significant based on their VO2, and that the mean difference, standard error difference, and 95% confidence interval of the difference for both are −6.68, 0.73, and −8.14, respectively. The physical component of QOL is significant in symptomatic individuals (0.005), but all other components are nonsignificant. Conclusion: The impact of COVID-19 on health-related QOL and cardiorespiratory fitness is higher in symptomatic individuals than symptomatic individuals.","PeriodicalId":8534,"journal":{"name":"Asian Journal of Pharmaceutical Research and Health Care","volume":"99 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135106183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of a new validated stability-indicating high-performance thin-layer chromatography method for determination of dosulepin HCl in bulk and marketed formulation with characterization of its degradants by liquid chromatography–Mass spectrometry 建立了一种新的高效薄层色谱法，用于测定散装和市售制剂中盐酸多舒乐平的含量，并采用液相色谱-质谱法对其降解物进行了表征

IF 0.4

Asian Journal of Pharmaceutical Research and Health Care Pub Date : 2023-01-01 DOI: 10.4103/ajprhc.ajprhc_2_23

A. Balap, Ravina Waghmare

{"title":"Development of a new validated stability-indicating high-performance thin-layer chromatography method for determination of dosulepin HCl in bulk and marketed formulation with characterization of its degradants by liquid chromatography–Mass spectrometry","authors":"A. Balap, Ravina Waghmare","doi":"10.4103/ajprhc.ajprhc_2_23","DOIUrl":"https://doi.org/10.4103/ajprhc.ajprhc_2_23","url":null,"abstract":"Aim: Dosulepin hydrochloride is a tricyclic antidepressant. It acts by inhibition of the reuptake of biogenic amine and increasing available neurotransmitter levels at the synaptic cleft. The objective of this work is to develop a new validated stability-indicating high-performance thin-layer chromatography (HPTLC) method for the determination of dosulepin hydrochloric acid (HCl) in bulk and marketed formulation and characterization of the degradation products by liquid chromatography–mass spectrometry (LC–MS). Materials and Methods: The HPTLC method development of dosulepin HCl was performed on aluminum plates precoated with silica gel 60 F254 using dichloromethane: toulene: methanol: glacial acetic acid (GAA) (4:4:2:0.2 v/v) with densitometric detection at 220 nm. The method validation was done using linearity, precision, accuracy, and robustness parameter. Results: Linearity range for dosulepin HCl was found in between 150 and 900 ng/band correlation coefficient was 0.996. The % relative standard deviation for accuracy and precision was found <2%. The developed and validated HPTLC method is simple, accurate, precise, and specific. Conclusion: This study concludes that the dosulepin HCl undergoes degradation to different extent under different stress conditions. From the peak purity profile studies, it was confirmed that the peak of the degradation product was not interfering with the peak of drugs. Major acidic and oxidation degradation products were isolated and characterized by LC–MS and probable degradation pathway for dosulepin HCl was determined.","PeriodicalId":8534,"journal":{"name":"Asian Journal of Pharmaceutical Research and Health Care","volume":"23 24 1","pages":"76 - 82"},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88652257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Methotrexate-induced Neutropenia Methotrexate-induced嗜中性白血球减少症

IF 0.4

Asian Journal of Pharmaceutical Research and Health Care Pub Date : 2023-01-01 DOI: 10.4103/ajprhc.ajprhc_15_23

KeshaAjaykumar Parmar, Maulin Mehta

引用次数: 0

Computational insights into the epilepsy-related phytoconstituents of Acacia farnesiana: In silico analysis, molecular modeling, and ADMET profiling 金合欢癫痫相关植物成分的计算分析:计算机分析、分子建模和ADMET分析

Asian Journal of Pharmaceutical Research and Health Care Pub Date : 2023-01-01 DOI: 10.4103/ajprhc.ajprhc_59_23

Payal Mittal, Shristi Gupta, GirishChandra Arya

{"title":"Computational insights into the epilepsy-related phytoconstituents of <i>Acacia farnesiana</i>: <i>In silico</i> analysis, molecular modeling, and ADMET profiling","authors":"Payal Mittal, Shristi Gupta, GirishChandra Arya","doi":"10.4103/ajprhc.ajprhc_59_23","DOIUrl":"https://doi.org/10.4103/ajprhc.ajprhc_59_23","url":null,"abstract":"Objective: This study aimed to evaluate the anticonvulsant potential of phytochemicals from Acacia farnesiana using molecular docking and compare their binding affinities with ethosuximide, a common anticonvulsant. Additionally, we conducted a comprehensive ADMET analysis of leucoxol, a promising phytochemical with strong docking scores against leucine-rich glioma-inactivated protein 1 (PDB ID-5Y30). Methods: Auto Dock Vina was employed for in silico analysis to predict binding affinities. Leucoxol exhibited significantly higher binding affinity (-7.9 kcal/mol) than ethosuximide (-4.9 kcal/mol), suggesting superior anticonvulsant potential. We thoroughly examined leucoxol’s ADMET profile to assess its pharmacokinetic and toxicological properties. Results: Comparative analysis indicated that leucoxol may be a more effective anticonvulsant with reduced toxicity compared to ethosuximide. It displayed strong binding and a favorable ADMET profile. Conclusion: Phytochemicals from Acacia farnesiana, especially leucoxol, exhibit promising binding affinities compared to ethosuximide, indicating their potential as anticonvulsant agents. Leucoxol, in particular, demonstrates strong anticonvulsant potential and a favorable ADMET profile, making it a candidate for further research as an anticonvulsant with reduced toxicity. However, additional experimental and clinical investigations are needed to confirm their efficacy and safety in treating convulsive disorders.","PeriodicalId":8534,"journal":{"name":"Asian Journal of Pharmaceutical Research and Health Care","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135106018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

IF 0.4

Asian Journal of Pharmaceutical Research and Health Care Pub Date : 2023-01-01 DOI: 10.4103/ajprhc.ajprhc_89_22

A. Tom, J. Mandumpala, Aleena Manoj, Neha Maria Baby, S. Mathai, Siji Antony

{"title":"Drug-related Problems among Inpatients of General Medicine Department of a Tertiary Care Hospital in South India","authors":"A. Tom, J. Mandumpala, Aleena Manoj, Neha Maria Baby, S. Mathai, Siji Antony","doi":"10.4103/ajprhc.ajprhc_89_22","DOIUrl":"https://doi.org/10.4103/ajprhc.ajprhc_89_22","url":null,"abstract":"Background: Identification of drug-related problems (DRPs) is a medication management service that can add value to individual patient care. Determination of DRPs daily is a promising approach for optimizing treatment. Objective: The objective of this study was to analyze the incidence of DRPs identified along with the risk factors that contribute to its development. Setting: This study was conducted in a tertiary care hospital in Central Kerala, India. Methods: A cross-sectional study was conducted among 300 newly admitted patients to the general medicine department. Patient medical records were reviewed in 3 stages – medication reconciliation, medication order review, and discharge summary review, and DRPs were categorized based on the Pharmaceutical Care Network Europe V9.1. Patient characteristics such as age, gender, polypharmacy, comorbidities, nonadherence, and type of illness were recorded. Results: Out of 300 patients, 78.7% had DRPs. The incidence of DRPs was found to be 0.26 cases/people-months. Although age >60 years, gender, polypharmacy, nonadherence, comorbidities, and chronic ailments were risk factors for DRPs, only polypharmacy and comorbidities could be proven statistically. Conclusion: DRPs are an emerging issue within the confines of the health-care system and should be scrutinized to avoid negative outcomes. A stage-wise analysis of patients who are at risk will ensure better patient care.","PeriodicalId":8534,"journal":{"name":"Asian Journal of Pharmaceutical Research and Health Care","volume":"32 1","pages":"22 - 28"},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85493514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of antimicrobial prophylaxis in surgical procedures in a tertiary care hospital in Southern India: A cross-sectional study 评估抗菌预防在外科手术在印度南部三级护理医院:一项横断面研究

Asian Journal of Pharmaceutical Research and Health Care Pub Date : 2023-01-01 DOI: 10.4103/ajprhc.ajprhc_98_23

Swathi Acharya, Ananyaa Agrawal

{"title":"Assessment of antimicrobial prophylaxis in surgical procedures in a tertiary care hospital in Southern India: A cross-sectional study","authors":"Swathi Acharya, Ananyaa Agrawal","doi":"10.4103/ajprhc.ajprhc_98_23","DOIUrl":"https://doi.org/10.4103/ajprhc.ajprhc_98_23","url":null,"abstract":"Context: Surgical site infections (SSIs) are the second-most common cause of health care-associated infections and are responsible for postoperative illness leading to increased morbidity and mortality. There are various preventive strategies against SSIs such as proper surgical technique, strict asepsis in the operating theater, control of infection within the hospital or general practice, and antibiotic prophylaxis. Widespread use of prophylactic antibiotics has the disadvantage of the emergence of multiresistant organisms. Thus, the implementation of proper surgical antimicrobial prophylaxis (SAP) practice is highly recommended to assess the pattern of SAP practiced in a tertiary care hospital in southern India. Subjects and Methods: A prospective, observational, cross-sectional study was conducted in a tertiary care hospital where data were collected from 175 inpatients admitted to the surgical ward. The pattern of SAP practice was analyzed using descriptive statistics. Results: The pattern of antibiotic prophylaxis revealed that the most commonly used agents were third-generation cephalosporins (57.71%), followed by broad-spectrum penicillins (18.86%), second-generation cephalosporins (13.71%), fluoroquinolones (4.57%), and antiamebic drugs (13.14%) mainly for gastrointestinal surgeries. Conclusions: Assessing the pattern of antimicrobial prophylaxis will help us to determine the appropriateness of the drugs prescribed with respect to the procedure and will help us to give feedback to the clinician and policymakers regarding the need for improvement in case of deviation in the practice compared to the guidelines given in the hospital antibiotic policy.","PeriodicalId":8534,"journal":{"name":"Asian Journal of Pharmaceutical Research and Health Care","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135106191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Management and outcomes of high-energy pilon fractures: A case of King Saud Medical City, KSA 高能量枕部骨折的治疗和结果:沙特国王医疗城一例

Asian Journal of Pharmaceutical Research and Health Care Pub Date : 2023-01-01 DOI: 10.4103/ajprhc.ajprhc_102_23

SaadeldinAhmed Idris, AhmedOnayzan Alshammari, AhmedMohammed Ahmed Abdalrahman, Hani Serhan, MajedMouaffek Majed Shogair, Hussain Alyassain, BashahMohammad Saleh Almustanir, HaniNouran Alharbi, Fahd Alshahrani, MashaelSultan Alsadoon, AbdulmohsinAdnan Alhabobi

{"title":"Management and outcomes of high-energy pilon fractures: A case of King Saud Medical City, KSA","authors":"SaadeldinAhmed Idris, AhmedOnayzan Alshammari, AhmedMohammed Ahmed Abdalrahman, Hani Serhan, MajedMouaffek Majed Shogair, Hussain Alyassain, BashahMohammad Saleh Almustanir, HaniNouran Alharbi, Fahd Alshahrani, MashaelSultan Alsadoon, AbdulmohsinAdnan Alhabobi","doi":"10.4103/ajprhc.ajprhc_102_23","DOIUrl":"https://doi.org/10.4103/ajprhc.ajprhc_102_23","url":null,"abstract":"Background: Despite being uncommon, pilon fractures are of interest to orthopedic surgeons because of the awkwardness of their treatment. Although various surgical techniques were used, poor outcomes are frequently encountered, and complications are highly prevalent. Objective: The objective of this study was to evaluate the clinical and radiographic outcomes of pilon fractures treated with a two-stage technique. Materials and Methods: The study included patients with tibial pilon fractures who had undergone two-stage procedures in King Saud Medical City (April 2017–March 2022). Fractures were categorized based on the Arbeitsgemeinschaftfur Osteosynthesefragen (AO) classification method. Outcomes were measured by the American Orthopedic Foot and Ankle Society (AOFAS) scoring system. Results: Twenty-one patients had tibial pilon fracture. Open fractures were seen in 23.8%, the majority was Gustilo type II in 60%. The mean follow-up was 24.7 months. The majority (47.6%) was AO type 43-B. Osteoarthritis was developed in 61.9%, and none mandates arthrodesis. Mean AOFAS was 86.91 points, it was excellent in 38.1%. Type 43 C fracture significantly had a poorer AOFAS score (P = 0.021). AOFAS score was significantly affected by fracture grade and association with fibular fracture, P = 0.025, and P = 0.019, respectively. Conclusion: Treatment for severe pilon fractures with a two-stage protocol yields favorable outcomes. Fewer soft-tissue complications and better articular reconstruction were the main benefits.","PeriodicalId":8534,"journal":{"name":"Asian Journal of Pharmaceutical Research and Health Care","volume":"157 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135104440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antioxidant Properties of Methanolic and Acetone Extracts of Pictacia palaestina, Verbena triphylla and Nigella sativum 牡丹、马鞭草和黑草甲醇和丙酮提取物的抗氧化性能

Asian Journal of Pharmaceutical Research and Health Care Pub Date : 2023-01-01 DOI: 10.4103/ajprhc.ajprhc_61_23

NessrinGhazi Alabdallat, Hana Alanazi

{"title":"Antioxidant Properties of Methanolic and Acetone Extracts of Pictacia palaestina, Verbena triphylla and Nigella sativum","authors":"NessrinGhazi Alabdallat, Hana Alanazi","doi":"10.4103/ajprhc.ajprhc_61_23","DOIUrl":"https://doi.org/10.4103/ajprhc.ajprhc_61_23","url":null,"abstract":"Aims: The aim of the study was to estimate the antioxidant characteristics of methanolic and acetone extracts of Pistacia palaestina, Verbena triphylla, and Nigella sativa. Materials and Methods: The biochemical antioxidant assays that used were total phenols and flavonoids, total antioxidant capacity, ferric reducing power and 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging. Results: The maximum antioxidant capacity and the ferric-reducing power of the examined plant extracts were shown in P. palaestina/methanol whereas N. sativa L./methanol was the lowest. The maximum scavenging activity of DPPH was shown in N. sativa L./acetone (IC50 = 2688 μg/ml), followed by, V. triphylla/acetone (IC50 = 573.5 μg/ml), N. sativa/methanol (IC50 = 437.7 μg/ml), V. triphylla/methanol (IC50 = 64 μg/ml), and P. palaestina methanol and acetone extracts (IC50 = 9.5 μ/g) being the lowest. Conclusion: The findings with methanol extract of P. palaestina methanol shown the highest antioxidant property which and can be due to the presence of high quantity of phenols and flavonoids in the methanol extract of this plant; moreover, N. sativa acetone extract has maximum DPPH-free radical scavenging activity. This may be because the acetone extract demonstrated capabilities to scavenge radicals remarkably for Nigella sativa L seeds.","PeriodicalId":8534,"journal":{"name":"Asian Journal of Pharmaceutical Research and Health Care","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135106008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Factors of venous thromboembolism among COVID-19 patients COVID-19患者静脉血栓栓塞的影响因素

IF 0.4

Asian Journal of Pharmaceutical Research and Health Care Pub Date : 2023-01-01 DOI: 10.4103/ajprhc.ajprhc_13_23

L. P. Low, F. Islahudin, S. Saffian

{"title":"Factors of venous thromboembolism among COVID-19 patients","authors":"L. P. Low, F. Islahudin, S. Saffian","doi":"10.4103/ajprhc.ajprhc_13_23","DOIUrl":"https://doi.org/10.4103/ajprhc.ajprhc_13_23","url":null,"abstract":"Context: Anticoagulants are used to prevent and treat venous thromboembolism (VTE), such as deep-vein thrombosis (DVT) and pulmonary embolism (PE) in COVID-19 for better outcomes. Aim: This study aims to explore clinical outcomes and factors affecting VTE among COVID-19 patients. Settings and Design: The study design involved a retrospective cohort study. Study Methods: Hospitalized COVID-19 patients in a tertiary hospital prescribed subcutaneous (SC) anticoagulants were included. Statistical Analysis Used: Multiple logistic regression was performed to determine factors affecting VTE among subjects. Results: A total of 450 patients were included. Types of anticoagulants include fondaparinux (n = 114, 38.1%), enoxaparin (n = 113, 37.8%), and heparin (n = 72, 24.1%). 423 (94.0%) patients were discharged well, 27 (6.0%) patients were admitted to the intensive care unit (ICU). The primary outcome was the prevalence of VTE, which occurred in 19.3% (n = 87) patients, with 80 (92.0%) reporting DVT and 7 (8.0%) reporting PE. The secondary outcome, which was the average length of hospital stay was 9.9 (±4.7) days. Factors of VTE occurrence were likely in patients not prescribed SC anticoagulants compared to those prescribed with SC anticoagulants (adjusted odds ratio [aOR] 54.330, 95% confidence interval [CI]: 7.086, 416.526), treatment with fondaparinux compared to heparin (aOR 2.502, 95% CI: 1.175, 5.327), and less likely in those discharged well compared to patients in the ICU (aOR 0.139, 95% CI: 0.053, 0.361). Conclusions: Careful monitoring is required to reduce VTE risk in COVID-19 patients.","PeriodicalId":8534,"journal":{"name":"Asian Journal of Pharmaceutical Research and Health Care","volume":"5 1","pages":"97 - 104"},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74181666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between low back pain, pelvic floor dysfunction, and diastasis rectus abdominis in postnatal delivery women 产后妇女腰痛、盆底功能障碍和腹直肌转移之间的关系

IF 0.4

Asian Journal of Pharmaceutical Research and Health Care Pub Date : 2023-01-01 DOI: 10.4103/ajprhc.ajprhc_102_22

Rishita Rai, Sudhakar Subramanian

{"title":"Association between low back pain, pelvic floor dysfunction, and diastasis rectus abdominis in postnatal delivery women","authors":"Rishita Rai, Sudhakar Subramanian","doi":"10.4103/ajprhc.ajprhc_102_22","DOIUrl":"https://doi.org/10.4103/ajprhc.ajprhc_102_22","url":null,"abstract":"Background: It is crucial to understand diastasis rectus abdominis (DRA) in postpartum women and how it affects them. DRA should be related to pelvic floor dysfunction (PFD) and low back pain (LBP). Prior researchers have contradictory findings in their studies. Objective: To estimate the prevalence of DRA and find the association between LBP, PFD, and DRA. Methodology: According to the eligibility criteria, 102 participants from Bengaluru were chosen for this study. The physical screening was performed to rule out DRA. Following informed consent, the participants have given the Oswestry Disability Index Questionnaire for LBP and Pelvic Floor Impact Questionnaire-7 for PFD. Subjects were divided into two classes: case and control. The data were analyzed using the Chi-square test and the Odds ratio using SPSS Software. Results: This analysis presents the findings of the prevalence of DRA and also the findings of rated LBP and PFD in both the groups. The degree of impact was determined to be P < 0.05. Conclusion: As an outcome, there is an association between LBP, PFD, and DRA.","PeriodicalId":8534,"journal":{"name":"Asian Journal of Pharmaceutical Research and Health Care","volume":"15 1","pages":"16 - 21"},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87791877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0