卵巢肿瘤的临床病理综述及印迹细胞学的诊断应用

IF 0.2 Q4 PHARMACOLOGY & PHARMACY
N. Patel, Rupali R. Bavikar, Y. Ingale, Yesha Lad, Arpana A. Dharwadkar, V. Viswanathan
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摘要

对于卵巢肿瘤的术中诊断,印迹细胞学是在20分钟内给出结果的方法,它不影响组织病理学标本的质量和效用。尽管在遗传学和影像学方面取得了进展,但组织病理学分析仍然是卵巢肿瘤诊断的主要手段。目的:描述卵巢肿瘤的发病率、年龄分布、组织学特征,并在可行的情况下将组织病理学诊断与印迹细胞学技术联系起来。材料和方法:2017年1月至2022年4月,共有200例卵巢肿瘤患者在皮姆普里的Dr. D. Y. Patil医学院医院和研究中心接受了这项双侧研究。结果:200例中,良性148例(74%),恶性52例(26%)。良性肿瘤的发病高峰在20 ~ 40岁,恶性肿瘤的发病高峰在40 ~ 60岁。卵巢肿瘤累及左卵巢(n = 104, 52%)多于累及右卵巢(n = 90, 45%)。200例中,卵巢表面上皮性肿瘤130例(65%),生殖细胞性肿瘤50例(25%),性索间质性肿瘤14例(7%),卵巢继发性/转移性肿瘤3例(3%)。148例(74%)印迹细胞学技术与组织病理学诊断的相关性为100%。结论:印迹细胞学诊断与卵巢肿瘤的组织病理学诊断相关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
ClinicoPathological Overview of Ovarian Tumors and Diagnostic Utility of Imprint Cytology
Introduction: For intra-operative diagnosis of ovarian tumors, imprint cytology is the method which gives result within 20 min. It does not affect the quality and utility of the specimen for histopathology. Despite advances in genetics and imaging, histopathological analysis remains the mainstay of ovarian tumor diagnosis. Aim: To describe incidence, age distribution, histological characteristics and whenever feasible, correlate the histopathological diagnosis of ovarian tumors with the imprint cytology technique. Materials and Methods: A total of 200 patients with ovarian tumors were included in this ambispective study from January 2017 to April 2022 at the Dr. D. Y. Patil Medical College, Hospital and Research Center, Pimpri. Results: One hundred and forty-eight (74%) of the 200 cases were benign, while 52 (26%) were malignant. The peak age incidence of benign tumors was in the second to fourth decades and malignant ovarian tumors was in fourth to sixth decades. Ovarian tumors involved the left ovary (n = 104, 52%) more than the right ovary (n = 90, 45%). Out of 200 cases, 130 cases (65%) were surface epithelial ovarian tumors, followed by 50 cases (25%) were germ cell tumors, followed by 14 cases (7%) were sex cord stromal tumors followed by 3 cases (3%) were secondary/metastatic tumors of ovary. Imprint cytology technique done on 148 cases (74%) showed 100% correlation with the histopathological diagnosis. Conclusion: Imprint cytology diagnosis correlated with the histopathological diagnosis of ovarian tumors.
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