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Treatment Outcomes of Pituitary Tumors at the University of Santo Tomas Hospital: 2004-2008 圣托马斯大学医院垂体肿瘤的治疗结果:2004-2008
Philippine journal of internal medicine Pub Date : 2010-07-23 DOI: 10.3860/PJIM.V47I3.1654
J. Fonte, E. Cunanan, B. Matawaran, L. Mercado-Asis
{"title":"Treatment Outcomes of Pituitary Tumors at the University of Santo Tomas Hospital: 2004-2008","authors":"J. Fonte, E. Cunanan, B. Matawaran, L. Mercado-Asis","doi":"10.3860/PJIM.V47I3.1654","DOIUrl":"https://doi.org/10.3860/PJIM.V47I3.1654","url":null,"abstract":"Results: Data of forty one patients (23 males, 18 females; mean age: 42 years, range: 19-68) were reviewed. Majority have clinically non functioning tumors (n=17), fol lowed by prolactinoma (n=12) and acromegaly (n=7). E ighty s ix percent were macroadenomas. Transphenoidal surgery (TSS) was the main treatment in 70% of patients (n=28) while dopamine agonist was used in another 28% (n=11). Diabetes insipidus occurred in 24% of cases. One patient died of hospital acquired pneumonia. Thirty one patients were evaluated after a mean of 1.4 years (range: 0.25 3.9 years). There was a decrease in visual disturbances (73 to 23%), headache (63 to 6%), signs and symptoms of hypogonadism (38 to 19%) and hypopituitarism (60 to 52%) before and after treatment, respectively. Hormonal control was achieved in 71% while radiological cure was achieved in 35%.","PeriodicalId":85270,"journal":{"name":"Philippine journal of internal medicine","volume":"47 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2010-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70066677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
PREVALENCE OF MALIGNANCY IN PATIENTS WITH THYROID INCIDENTALOMAS DETECTED BY 18 F-FLUORODEOXYGLUCOSE POSITRON EMISSION TOMOGRAPHY 18f -氟脱氧葡萄糖正电子发射断层扫描检测甲状腺偶发瘤患者恶性肿瘤的发生率
Philippine journal of internal medicine Pub Date : 2010-07-23 DOI: 10.3860/PJIM.V47I2.1645
J. María, Ibarra O. Co, Michael Villa, J. Santiago
{"title":"PREVALENCE OF MALIGNANCY IN PATIENTS WITH THYROID INCIDENTALOMAS DETECTED BY 18 F-FLUORODEOXYGLUCOSE POSITRON EMISSION TOMOGRAPHY","authors":"J. María, Ibarra O. Co, Michael Villa, J. Santiago","doi":"10.3860/PJIM.V47I2.1645","DOIUrl":"https://doi.org/10.3860/PJIM.V47I2.1645","url":null,"abstract":"Background: Thyroid incidentalomas detected by 18 F-Fluorodeoxyglucose Positron Emission Tomography (FDG-PET) have been reported in 1.1 to 2.9% of scans performed. Previous studies have determined the prevalence of thyroid malignancy in these patients to be 14-72%. Objective: We undertook a retrospective study to determine the prevalence of thyroid incidentalomas in our center, and evaluated the corresponding prevalence for malignancy in these patients. Results: A total of 2,912 FDG-PET scans were performed on 1,855 patients, of which 56 (3.0%) presented with a thyroid incidentaloma (40 focal and 16 diffuse). Among the 22 patients who had an ultrasound, 15 presented with solid nodules (10 focal and 5 diffuse), while 5 were negative for any lesions (4 focal and 1 diffuse). Of 13 patients who had a subsequent FDGPET scan, 8 had resolution of the hypermetabolic foci (61.5%), of which 5 were focal and 3 diffuse. Only 1 of 6 incidentalomas whose histological diagnoses were available showed malignancy (papillary carcinoma). Other cytologic diagnoses include colloid goiter and lymphocytic thyroiditis. Conclusion: The prevalence of thyroid malignancy in focal incidentalomas is 1 in 12 (8.3%) and 1 in 17 in all incidentalomas (5.9%). Our experience indicates that the prevalence rates are much lower than that previously reported. Nevertheless, the prevalence rates are significantly elevated to warrant further evaluation, including an imaging procedure and fine needle aspiration biopsy.","PeriodicalId":85270,"journal":{"name":"Philippine journal of internal medicine","volume":"47 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2010-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70066784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Parental Notification and the Minor Patient 父母通知和未成年病人
Philippine journal of internal medicine Pub Date : 2010-07-23 DOI: 10.3860/PJIM.V47I3.1649
Rodel V Capule
{"title":"Parental Notification and the Minor Patient","authors":"Rodel V Capule","doi":"10.3860/PJIM.V47I3.1649","DOIUrl":"https://doi.org/10.3860/PJIM.V47I3.1649","url":null,"abstract":"","PeriodicalId":85270,"journal":{"name":"Philippine journal of internal medicine","volume":"47 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2010-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70066991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Autoimmune Hepatitis as Initial Presentation of Systemic Lupus Erythematosus 自身免疫性肝炎是系统性红斑狼疮的初始表现
Philippine journal of internal medicine Pub Date : 2010-07-23 DOI: 10.3860/PJIM.V47I2.1648
L. Hamijoyo, Andrew T. Dysangco, S. Navarra
{"title":"Autoimmune Hepatitis as Initial Presentation of Systemic Lupus Erythematosus","authors":"L. Hamijoyo, Andrew T. Dysangco, S. Navarra","doi":"10.3860/PJIM.V47I2.1648","DOIUrl":"https://doi.org/10.3860/PJIM.V47I2.1648","url":null,"abstract":"Laboratory work up: hemoglobin of 72g/L, Serum bilirubin 26.4U/L, ALT 281U/L, AST 355U/L, alkaline phosphatase 275U/L, albumin 2.9mg/dL, globulin 4.2mg/dL. C3 0.62g/L, negative serology for viral hepatitis, urinalysis: urine protein 3+ (0.9g/24hours), RBC loaded/hpf, WBC 4-8/hpf, hyaline and granular casts. ANA 1:2560 speckled, anti-dsDNA 34.3IU/ml, moderately positive anti-Ro/SSA, anti-cardiolipin antibodies-negative.","PeriodicalId":85270,"journal":{"name":"Philippine journal of internal medicine","volume":"47 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2010-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70066977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diabetes Mellitus is Not Only A Risk Factor But A Cardiovascular Disease 糖尿病不仅是一个危险因素，而且是一种心血管疾病
Philippine journal of internal medicine Pub Date : 2010-07-23 DOI: 10.3860/PJIM.V47I2.1642
H. Calleja
{"title":"Diabetes Mellitus is Not Only A Risk Factor But A Cardiovascular Disease","authors":"H. Calleja","doi":"10.3860/PJIM.V47I2.1642","DOIUrl":"https://doi.org/10.3860/PJIM.V47I2.1642","url":null,"abstract":"Diabetes Mell itus (DM) is a chronic systemic disease characterized by disorders in metabolism of insulin, carbohydrate, fat and protein and impairment of structure and function of blood vessels; the early manifestations are metabolic and the complications result from vascular disease. Vascular changes may precede several years overt DM. Both type 1 and type 2 DM are vulnerable to microvascular and macrovascular complications. The relation of glucose and coronary artery disease is continuous and graded across the range of nondiabetic glucose values, independent of traditional and nontraditional risk factors with no gender difference.","PeriodicalId":85270,"journal":{"name":"Philippine journal of internal medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2010-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70066076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Smoking Behaviour and Practices and Smoking Cessation in the General Population and among Health Care Professionals in Metro Manila 马尼拉大都会一般人群和卫生保健专业人员的吸烟行为和做法与戒烟
Philippine journal of internal medicine Pub Date : 2010-07-23 DOI: 10.3860/PJIM.V47I3.1655
M. Angela, L. Tan, G. Dy-Agra
{"title":"Smoking Behaviour and Practices and Smoking Cessation in the General Population and among Health Care Professionals in Metro Manila","authors":"M. Angela, L. Tan, G. Dy-Agra","doi":"10.3860/PJIM.V47I3.1655","DOIUrl":"https://doi.org/10.3860/PJIM.V47I3.1655","url":null,"abstract":"Background: A sizeable amount of the population continues to smoke despite global efforts in smoking cessation; unfortunately smoking prevalence is especially high in the productive age group, i.e., 22-65 years old. Even health care professionals who are aware of the ill effects of smoking have difficulty quitting. Objective: The main aim of this study is to investigate the smoking behavior and reasons for failure of smoking cessation in the general population and among health care professionals in Metro Manila. Methodology: Random sampling of cities and participants was done. Cities included were Pasig, Mandaluyong, San Juan, Paranaque, Makati, Quezon City, Manila, Paranaque and Muntinlupa; hospitals included were CSMC, TMC, SLMC and UP-PGH. The Wisconsin Inventory of Smoking Dependence Motives (WISDM-68), a standardized questionnaire, was used. Results: A total f 4,000 survey forms were distributed and 1,388 (34.7%) were returned; 1,249 (90%) from the general population and 139 (10%) from health care professionals. Principal reasons for smoking and difficulty quitting in the general population are social and environmental goads, particularly in the workplace, and associative processes. Moreover, health care professionals are high in the motives that predict relapse, namely cognitive enhancement, social and environmental goads and negative reinforcement, in that order. Conclusion: With a more in depth understanding of smoking behavior and practices and why most smokers fail to quit, physicians would be more adept in motivating and counseling each smoking patient to quit.","PeriodicalId":85270,"journal":{"name":"Philippine journal of internal medicine","volume":"47 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2010-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70066697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Insulinoma and Prolactinoma in a Young Female: A Variant of Multiple Endocrine Neoplasia 1 (MEN-1) 年轻女性胰岛素瘤和泌乳素瘤:多发性内分泌肿瘤1 (MEN-1)的一种变体
Philippine journal of internal medicine Pub Date : 2010-07-23 DOI: 10.3860/PJIM.V47I3.1656
M. J. Cardino, F. Lantion-Ang
{"title":"Insulinoma and Prolactinoma in a Young Female: A Variant of Multiple Endocrine Neoplasia 1 (MEN-1)","authors":"M. J. Cardino, F. Lantion-Ang","doi":"10.3860/PJIM.V47I3.1656","DOIUrl":"https://doi.org/10.3860/PJIM.V47I3.1656","url":null,"abstract":"Background: MEN-1, a rare disorder, consists of parathyroid adenoma, entero-pancreatic tumor and pituitary tumor. We report a 20-year old female with insulinoma and prolactinoma without parathyroid adenoma to complete the triad of MEN-1. A MEN-1 variant has been reported with high penetrance of prolactinoma and another endocrine tumor, however, validity of this variant is not yet universally accepted.","PeriodicalId":85270,"journal":{"name":"Philippine journal of internal medicine","volume":"47 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2010-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70066759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Ultrasound Overestimates the Area of Necrosis during Radiofrequency Ablation in Porcine Livers 超声高估猪肝射频消融过程中的坏死面积
Philippine journal of internal medicine Pub Date : 2010-07-23 DOI: 10.3860/pjim.v47i3.1653
E. G. Santi, S. Lu, M. Milo, Redigo Aguilar, Hendra Nurjadin, Susanne Gosalvez-Pe, Stephen N. Wong
{"title":"Ultrasound Overestimates the Area of Necrosis during Radiofrequency Ablation in Porcine Livers","authors":"E. G. Santi, S. Lu, M. Milo, Redigo Aguilar, Hendra Nurjadin, Susanne Gosalvez-Pe, Stephen N. Wong","doi":"10.3860/pjim.v47i3.1653","DOIUrl":"https://doi.org/10.3860/pjim.v47i3.1653","url":null,"abstract":"Results: There was a trend for increased horizontal diameter for both ultrasound (RFA 6 mins=3.8+0.5cm vs. RFA 12 mins = 5.1+1.0cm; p = 0.079) and grossly (RFA 6mins = 2.7+0.27cm vs. RFA 12mins = 3.1+0.24cm; p = 0.068) with increased RFA duration from 6 to 12 minutes, which was not observed for the longitudinal diameter. Ultrasound consistently overestimated the actual necrotic diameter by 1.3+0.8cm (range = 0.4 to 3.6cm) (p = 0.01) whether RFA was performed for 6 (1.0+0.3cm) or 12 (1.8+1.2cm) minutes.","PeriodicalId":85270,"journal":{"name":"Philippine journal of internal medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2010-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70066632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pituitary Abscess Mimicking Pituitary Adenoma: A Review of Three Cases seen at the Philippine General Hospital from 2004-2007 垂体脓肿模拟垂体腺瘤:回顾2004-2007年在菲律宾总医院看到的3例病例
Philippine journal of internal medicine Pub Date : 2010-07-23 DOI: 10.3860/PJIM.V47I3.1657
M. V. Lemoncito, F. Lantion-Ang
{"title":"Pituitary Abscess Mimicking Pituitary Adenoma: A Review of Three Cases seen at the Philippine General Hospital from 2004-2007","authors":"M. V. Lemoncito, F. Lantion-Ang","doi":"10.3860/PJIM.V47I3.1657","DOIUrl":"https://doi.org/10.3860/PJIM.V47I3.1657","url":null,"abstract":"Clinical Presentation: We report 3 patients with pituitary abscesses at the Philippine General Hospital since 2004. Case 1 is a 24 year-old male with a 2year history of severe generalized headache, blurring of vision, and hypothyroid symptoms. Case 2 is a 42 yearold woman admitted due to severe generalized headache, amenorrhea and polyuria of 3 months duration. Case 3 is a 37 year-old female with a 3-year history of headache and amenorrhea.","PeriodicalId":85270,"journal":{"name":"Philippine journal of internal medicine","volume":"80 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2010-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70066831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Quality of care and Outcomes of Diabetic Extremity Patients after the Implementation of the Revised Diabetes Extremity Care Team Protocol of The Philippine General Hospital 实施菲律宾总医院修订的糖尿病肢体护理小组协议后，糖尿病肢体患者的护理质量和结局
Philippine journal of internal medicine Pub Date : 2010-07-23 DOI: 10.3860/PJIM.V47I2.1643
M. J. Cardino, C. V. Josol, I. T. Isip-Tan
{"title":"Quality of care and Outcomes of Diabetic Extremity Patients after the Implementation of the Revised Diabetes Extremity Care Team Protocol of The Philippine General Hospital","authors":"M. J. Cardino, C. V. Josol, I. T. Isip-Tan","doi":"10.3860/PJIM.V47I2.1643","DOIUrl":"https://doi.org/10.3860/PJIM.V47I2.1643","url":null,"abstract":"Diabetic foot syndrome affects up to 20% of patients with diabetes at least once in their lifetime.1 In other words, it affects 1 out of 5 diabetics once in his lifetime with relevant consequences both on lower limb survival and general morbidity. Diabetes is the most frequent determined of lower limb amputations in developed countries. Lower limb complications are the major contributors to hospitalization of patients with diabetes and they account for the vast majority of in-hospital stay and resource consumption among these patient population.","PeriodicalId":85270,"journal":{"name":"Philippine journal of internal medicine","volume":"47 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2010-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70066143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
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