Insulinoma and Prolactinoma in a Young Female: A Variant of Multiple Endocrine Neoplasia 1 (MEN-1)

Abstract

Background: MEN-1, a rare disorder, consists of parathyroid adenoma, entero-pancreatic tumor and pituitary tumor. We report a 20-year old female with insulinoma and prolactinoma without parathyroid adenoma to complete the triad of MEN-1. A MEN-1 variant has been reported with high penetrance of prolactinoma and another endocrine tumor, however, validity of this variant is not yet universally accepted.