Asian Journal of Biomedical and Pharmaceutical Sciences最新文献_第3页

A review on: Soil microbes effect on human health. 土壤微生物对人体健康的影响研究进展。

Asian Journal of Biomedical and Pharmaceutical Sciences Pub Date : 2020-01-01 DOI: 10.35841/2249-622X.71.19056

P. PatelAyushi, T. R. Sharma, R. Bhavesh

引用次数: 0

Commentary on treatment patterns among recurrent/metastatic soft tissue sarcoma by medical oncologists 医学肿瘤学家对复发/转移性软组织肉瘤治疗模式的评论

Asian Journal of Biomedical and Pharmaceutical Sciences Pub Date : 2020-01-01 DOI: 10.35841/2249-622x.69.9876

K. Nakano

引用次数: 0

Highlights of Biomedical and Pharmaceutical Sciences 生物医学和制药科学亮点

Asian Journal of Biomedical and Pharmaceutical Sciences Pub Date : 2020-01-01 DOI: 10.35841/2249-622X.69.EDITORIAL

Karthik Yadav Janga

引用次数: 0

Pros and Challenges to Pharmacists in Prescribing Practice. 药师在处方实践中的优势与挑战。

Asian Journal of Biomedical and Pharmaceutical Sciences Pub Date : 2020-01-01 DOI: 10.35841/2249-622x.70.7832

Majid Khan

{"title":"Pros and Challenges to Pharmacists in Prescribing Practice.","authors":"Majid Khan","doi":"10.35841/2249-622x.70.7832","DOIUrl":"https://doi.org/10.35841/2249-622x.70.7832","url":null,"abstract":"Pharmacists are the hearts of health care team and independent prescribers in United Kingdom and other developed countries. Nowadays pharmacists oriented to patient care rather traditional mercantile products orientation. Clinical Pharmacy is the combined agreement between physician and pharmacist in which pharmacist prescribing and providing patient care. The health care team is fragile in the absence of pharmacist, literature supported prescription by pharmacists and the members include physicians, stakeholders and patients, but some physicians not supported them due to loss of dignity, deskilled junior physicians and some considered them deficient of well diagnostic skills. Provision of drug therapy without competent clinical pharmacist is impossible and incomplete. The implementation of pharmacists prescribing can effectively decrease burdens and workload from the shoulders of physicians to provide them time for complex diseases, facilitate pharmacists regarding jobs issues instead of five years degree of Doctor of Pharmacy, patient counseling and educations, reduction of polypharmacy and iatrogenic diseases as well as to stabilize the health care triangle.","PeriodicalId":8517,"journal":{"name":"Asian Journal of Biomedical and Pharmaceutical Sciences","volume":"30 1","pages":"26-28"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74119738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Neuroprotective Property of Madhunashini Vati in Diabetic Rat 麻瓜对糖尿病大鼠神经保护作用的评价

Asian Journal of Biomedical and Pharmaceutical Sciences Pub Date : 2019-01-01 DOI: 10.35841/2249-622X.67.19-257

A. Rawat, Arun Kumar, P. Kothiyal

{"title":"Evaluation of Neuroprotective Property of Madhunashini Vati in Diabetic Rat","authors":"A. Rawat, Arun Kumar, P. Kothiyal","doi":"10.35841/2249-622X.67.19-257","DOIUrl":"https://doi.org/10.35841/2249-622X.67.19-257","url":null,"abstract":"The present study was designed to evaluate the Neuroprotection property of Madhunashini Vati in Diabetic Rat. Eight groups of rat and each group comprising of six animals were employed in the present study. During the experiment different doses of Madhunashini Vati (125, 250, 500 mg/kg) was administered. Insulin (4 IU/kg body weight s.c) was administered daily before the global ischemia in diabetic rats. Rats were treated with Streptozotocin (STZ) 65 mg/kg i.p for the induction of Diabetes for 14 days. Rats were anaesthetized by using chloral hydrate (400 mg/kg, i.p) and Global cerebral ischemia was induced by occluding the carotid arteries, reperfusion was allowed for 24 hours. At the end of study, total Serum Glucose level, Serum Triglyceride level, Thiobarbituric Acid Reactive Substances(TBARS) and Cerebral Infarct size was estimated for the Neuroprotection property. Administration of Madhunashini Vati, showed reduction in the serum glucose level, serum triglycerides level, cerebral infarct size and increases in body weight. In the present study we observed that the madhunashini vati significantly improved cerebral ischemia. Results indicate that Madhunashini Vati (MV) is a good neuroprotective and could be used as a therapeutic treatment in brain stroke. And it is likely to be responsible for the free radical scavenging activity and rejuvenate the beta cells observed.","PeriodicalId":8517,"journal":{"name":"Asian Journal of Biomedical and Pharmaceutical Sciences","volume":"54 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75896728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development and validation of an Enzyme Linked Immunosorbent Assay (ELISA) for gentamicin quantification in dried blood spot samples 开发和验证酶联免疫吸附法(ELISA)定量庆大霉素在干血斑样品

Asian Journal of Biomedical and Pharmaceutical Sciences Pub Date : 2019-01-01 DOI: 10.35841/2249-622x.66.18-1176

Teng Meng, Abdel Qader Al Bawab, A. Hawwa, J. McElnay

引用次数: 2

A pilot study to evaluate alternative approaches for treatment of urinary tract infections in dogs. 一项初步研究，评估治疗狗尿路感染的替代方法。

Asian Journal of Biomedical and Pharmaceutical Sciences Pub Date : 2019-01-01 DOI: 10.35841/2249-622x.66.18-1172

E. Biasibetti, M. Capucchio, T. Cocca, MauroBigliati, N. Bruni, E. Martello

引用次数: 2

Preventive effects of soy lecithin in combination with flavonoids on stz induced Diabetes Mellitus in rats 大豆卵磷脂联合黄酮类化合物对stz诱导大鼠糖尿病的预防作用

Asian Journal of Biomedical and Pharmaceutical Sciences Pub Date : 2019-01-01 DOI: 10.35841/2249-622X.67.19-253

Zade Kv, Gulkari Vd

{"title":"Preventive effects of soy lecithin in combination with flavonoids on stz induced Diabetes Mellitus in rats","authors":"Zade Kv, Gulkari Vd","doi":"10.35841/2249-622X.67.19-253","DOIUrl":"https://doi.org/10.35841/2249-622X.67.19-253","url":null,"abstract":"The present research work was design to investigate the anti-diabetic effect of Crude Soy lecithin (CSL) in combination with Flavonoids. Various dosed of CSL, quercetin and rutin were standardized and effective dose of CSL, quercetin and rutin was selected. Male Sprague Dawley rats weighing (200-225 g) were subjected to overnight fasting to induced diabetics by STZ (60 mg/kg i.p.) and blood sample was collected after 72 hrs to conform diabetics. Rats with blood glucose level ≥ 200 mg/dl were selected for further study. A dose of combination of CSL and quercetin with rutin p.o. was administered 60 min prior to blood sample withdrawal for estimation of glucose level. Positive control group were treated with STZ injected rats and negative control with metformin (100 mg/kg bw). Effect of CSL in combination with Flavonoids on Blood glucose level, Total Cholesterol level and Total Triglyceride level was evaluated. The results suggested treatment with CSL, quercetin and rutin were significantly decrease plasma glucose, cholesterol and triglyceride level in rats as compared to STZDiabetic rats. CSL show anti-diabetic effect alone and in combination with Flavonoids on STZ Induced Diabetes Mellitus (DM) in Rats.","PeriodicalId":8517,"journal":{"name":"Asian Journal of Biomedical and Pharmaceutical Sciences","volume":"21 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91434638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of prescription patterns and drug use across the Kurdistan region. 库尔德斯坦地区处方模式和药物使用评估。

Asian Journal of Biomedical and Pharmaceutical Sciences Pub Date : 2019-01-01 DOI: 10.35841/2249-622X.67.19-193

Rawaz D. Tawfeeq, Tarin Tahssen Obied, A. Ommar

{"title":"Assessment of prescription patterns and drug use across the Kurdistan region.","authors":"Rawaz D. Tawfeeq, Tarin Tahssen Obied, A. Ommar","doi":"10.35841/2249-622X.67.19-193","DOIUrl":"https://doi.org/10.35841/2249-622X.67.19-193","url":null,"abstract":"Errors in drug prescriptions are the most common preventable medication errors encountered in clinical practices worldwide. The aim of this research is to examine the pattern of prescriptions and drug use in the Kurdistan region and to determine whether the drug prescribing was based on rational therapeutic consideration. A cross sectional-observational study was conducted in the Kurdistan region of Iraq over a period of five months. A total of 1000 prescriptions were selected randomly from different pharmacies and data obtained from each prescription. In these prescriptions a total of 2878 medications were prescribed. The percentage of medications including antibiotics, supplement, non-steroidal antiinflammatory drugs and other painkillers 51.8%, 44.2%, 31.8%, and 21.8% per encounter respectively. The average number of drugs per prescription was 2.8. Drugs prescribed by generic name were 27% and more than 98 per cent of prescriptions were handwritten. The duration of therapy was mentioned in 56.5% of prescriptions. However, the dose and dosage form of medications were recorded 62% and 87.3% respectively. The percentage of prescriptions signed by the prescriber was 88.1%.","PeriodicalId":8517,"journal":{"name":"Asian Journal of Biomedical and Pharmaceutical Sciences","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87340541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Docking study and result conclusion of heterocyclic derivatives having urea and acyl moiety. 脲酰基杂环衍生物的对接研究及结果结论。

Asian Journal of Biomedical and Pharmaceutical Sciences Pub Date : 2019-01-01 DOI: 10.35841/2249-622X.67.19-082

Rakhi Mishra, A. Mazumder, R. Mazumder, Prem Shankar Mishra, Preeti Chaudhary

{"title":"Docking study and result conclusion of heterocyclic derivatives having urea and acyl moiety.","authors":"Rakhi Mishra, A. Mazumder, R. Mazumder, Prem Shankar Mishra, Preeti Chaudhary","doi":"10.35841/2249-622X.67.19-082","DOIUrl":"https://doi.org/10.35841/2249-622X.67.19-082","url":null,"abstract":"In the field of molecular modeling, Docking is a method which predicts the preferred orientation of one molecule to a second when bound to each other to form a stable complex. Knowledge of the preferred orientation in turn may be used to predict the strength of association or binding affinity between two molecules. In this study a series of synthesized compounds were evaluated for focusing on binding modes, potential interactions and specific binding sites. Chemically compounds bear both the moiety acyl as well as urea and their interaction by using in silico study was investigated with beta tubulin protein that interferes with the tubulin-microtubule equilibrium, crucial for cellular mitosis. In silico studies revealed that synthesized and tested compounds show 1-7 no. of interactions with amino acids of tubulin protein. Docking study was done by using Autodock, it was found that among different synthesized compound some shows the highest and best scoring pose (lowest energy) which was -2.94 Kcal/mole between N (11) and Leucine (113) and -3.09 between N (11) and Alanine (149). Compounds with amino, hydroxy, methyl, methoxy, trimethoxy and dimethoxy substitution in derivatives of acyl urea gave an idea that urea and acyl when used in combination in different synthesized compounds show good antitumor activity.","PeriodicalId":8517,"journal":{"name":"Asian Journal of Biomedical and Pharmaceutical Sciences","volume":"44 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85066712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5