Asian Journal of Biochemistry最新文献_第5页

Subchronic Toxicity of Acrylamide in Fried Rice and Preventive Effect of Grape Leaves 丙烯酰胺在炒饭中的亚慢性毒性及葡萄叶的预防作用

Asian Journal of Biochemistry Pub Date : 2016-02-01 DOI: 10.3923/AJB.2016.68.81

M. Osman, R. Romeilah, M. H. Elgammal, Eman S. Ramis, Randa S. Hasan

引用次数: 12

Antioxidant Activity of Cinnamomum iners Leaves Standardized Extract 肉桂叶标准提取物的抗氧化活性研究

Asian Journal of Biochemistry Pub Date : 2016-02-01 DOI: 10.3923/AJB.2016.90.96

F. Mustaffa, Zainuriah Hassan, M. Asmawi

引用次数: 2

Antidiabetic and Antidyslipidemic Effect of Ethanolic Extract of Alternanathera pungens on Alloxan-Induced Diabetic Rats 红花乙醇提取物对四氧嘧啶诱导的糖尿病大鼠的降糖和降血脂作用

Asian Journal of Biochemistry Pub Date : 2016-02-01 DOI: 10.3923/AJB.2016.82.89

Owa Stephen Olugbemiga, O. Grace, Taiwo Adeolu Adeola, Edewor-Ikupoyi There Ibibia, Okosun Jenifer Akhere, Otohiniyi David Adeiza, Akujobi Yvonne Oluchi, Nwonuma Charles Obiora, A. Stephen

引用次数: 6

HPTLC Analysis of Stem Bark Extracts of Terminalia chebula Retz. for Alkaloid Profile 慈母茎皮提取物的hplc分析。查阅生物碱资料

Asian Journal of Biochemistry Pub Date : 2016-02-01 DOI: 10.3923/AJB.2016.97.103

Iwin C. Varkey, G. Kasthuri

引用次数: 6

Effects of Extract of Spilanthes uliginosa (SW) on Total Protein, Albumin, Total and Conjugated Bilirubin in Ethylene Glycol Exposed Albino Rats 赤芍提取物对乙二醇暴露的白化大鼠总蛋白、白蛋白、总胆红素及偶联胆红素的影响

Asian Journal of Biochemistry Pub Date : 2016-01-01 DOI: 10.3923/AJB.2016.53.58

A. Uraku, N. Ezeani, C. Ezeali, F. U. Ali, C. Afiukwa, L. N. Ebenyi

{"title":"Effects of Extract of Spilanthes uliginosa (SW) on Total Protein, Albumin, Total and Conjugated Bilirubin in Ethylene Glycol Exposed Albino Rats","authors":"A. Uraku, N. Ezeani, C. Ezeali, F. U. Ali, C. Afiukwa, L. N. Ebenyi","doi":"10.3923/AJB.2016.53.58","DOIUrl":"https://doi.org/10.3923/AJB.2016.53.58","url":null,"abstract":"Effects of leaf extract of Spilanthes uliginosa (SW) on total protein, albumin, total and conjugated bilirubin levels in ethylene glycol exposed albino rats were studied. The animals were divided into 3 groups namely; A, B and C and groups A and B were subdivided into 2; AI, A2, B1 and B2. All the groups and subgroups contained 6 albino rats each and were given water and food ad libitum. Groups A1 and B1 with A2 and B2 were treated with 1.85 mg kgG and 3.70 mg kgG of 90% ethylene glycol intraperitoneally once, respectively. Groups B1 and B2 were also given 1 mL of the plant extract, respectively by oral incubation for 21 consecutive days while group C received only the water and food. The average body weights of the treated groups decreased significantly at p<0.05 compared to control. The result showed no significant change at p<0.05 in total protein levels and significant decrease in albumin, total and direct bilirubin levels compare to control. The result obtained suggests toxicity of ethylene glycol and the ability of the plant extract to affect the levels of the analyzed parameters.","PeriodicalId":8510,"journal":{"name":"Asian Journal of Biochemistry","volume":"37 1","pages":"53-58"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86355872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chemical Characterization of Enzymatically Treated Morinda Juice 酶处理马戟达汁的化学特性

Asian Journal of Biochemistry Pub Date : 2016-01-01 DOI: 10.3923/AJB.2016.14.23

D. Nivas, D. Gaikwad

引用次数: 1

Real-Time Polymerase Chain Reaction for Halal Authentication of Gelatin in Soft Candy 实时聚合酶链反应法测定软糖明胶的清真性

Asian Journal of Biochemistry Pub Date : 2016-01-01 DOI: 10.3923/AJB.2016.34.43

Theresia Sepminarti, Sudjadi, Herllya Selvi Wardani, A. Rohman

{"title":"Real-Time Polymerase Chain Reaction for Halal Authentication of Gelatin in Soft Candy","authors":"Theresia Sepminarti, Sudjadi, Herllya Selvi Wardani, A. Rohman","doi":"10.3923/AJB.2016.34.43","DOIUrl":"https://doi.org/10.3923/AJB.2016.34.43","url":null,"abstract":"Currently, along with the development of science and technology, the diversification of food products occurs in the market. Food products can contain non-halal components like porcine gelatine. One of food suspected to use gelatine is soft candy. Gelatin can be made from pork or beef or other animal. The presence of porcine gelatine in any food products is not allowed for Moslem community, therefore an analytical method offering reliable results must be developed. This study is intended to use Real-Time Polymerase Chain Reaction (RT-PCR) for analysis of porcine gelatine in soft candy. Isolation of DNA was performed with mitochondrial DNA Isolation Kit K280-50 (Bio-Vision). The DNA was analyzed by RT-PCR using primer D-Loop 318. Analysis for the primer specificity was performed on fresh tissue (pig, cows, chickens, goats and rats) and gelatin sources (beef, pigs and catfish). Primer D-loop318 can amplify porcine DNA at the optimum temperature 61.4°C. Repeatability test demonstrated amplification of all positive response samples containing porcine DNA in serial dilution of 10000-1 pg). The Coefficient of Variation (CV) is 6.32%. The repeatability test was also performed on soft candy 100% having CV of 1.06%. The commercial soft candy samples evaluated do not contain porcine DNA.","PeriodicalId":8510,"journal":{"name":"Asian Journal of Biochemistry","volume":"37 1","pages":"34-43"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85724224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Phytochemical, Antihyperglycaemic and Lipid Profile Effects of Methanol Extract Fraction of Ricinus comminus Seeds in Alloxan Induced Diabetic Male Wistar Albino 蓖麻种子甲醇提取物对四氧嘧啶诱导的糖尿病雄性Wistar白化患者的植物化学、降糖和血脂作用

Asian Journal of Biochemistry Pub Date : 2016-01-01 DOI: 10.3923/AJB.2016.24.33

F. C. N. Okwesili, C. Paul, E. Parker, Uroko Robert Ikechukwu

{"title":"Phytochemical, Antihyperglycaemic and Lipid Profile Effects of Methanol Extract Fraction of Ricinus comminus Seeds in Alloxan Induced Diabetic Male Wistar Albino","authors":"F. C. N. Okwesili, C. Paul, E. Parker, Uroko Robert Ikechukwu","doi":"10.3923/AJB.2016.24.33","DOIUrl":"https://doi.org/10.3923/AJB.2016.24.33","url":null,"abstract":"The study investigated phytochemical, antihyperglycaemic and lipid profile effects of methanol extract fraction of Ricinus comminus seeds in alloxan induced diabetic male Wistar albino rats alloxan. Eighteen mice were used for the lethal dose (LD50) study while 54 Wistar albino male rats were used for the antihyperglycaemic and lipid profile, respectively. The result of the phytochemical analysis showed the richness of the extract in important phytochemicals that could confer some health benefits. The methanol extract fraction had LD50>5000 mg kgG 1 b.wt., which indicate that the extract was safe to larger extent. The baseline blood glucose concentration showed non-diabetic glucose level 105.10±4.61 mg dLG. Diabetes was induced with alloxan monohydrate. Significant decrease (p<0.05) in blood glucose levels in the test animals were observed when compared with positive control. The extract had significant effect on the blood glucose levels and lipid profile of the treated rats closer to that of the standard drug (metformin) with the serum total cholesterol and triacylglycerol levels decreasing significantly (p<0.05) in all test groups relative to positive control. However, serum HDL showed significant increase (p<0.05) in group 4 and 5 when compared with positive control. The results of the study showed that the methanol extract fraction of Ricinus communis seeds exhibited significant antihyperglycaemic activities against alloxan induced diabetes in Wistar albino rats. It suggests that the methanol extract fraction possess bioactive compounds that when properly harnessed could help in improving the health state of diabetic patients.","PeriodicalId":8510,"journal":{"name":"Asian Journal of Biochemistry","volume":"114 1","pages":"24-33"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80793815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Cinnamomum iners Leaves as an Alternative Therapy for Diabetes 肉桂叶作为糖尿病的替代疗法

Asian Journal of Biochemistry Pub Date : 2016-01-01 DOI: 10.3923/AJB.2016.44.52

F. Mustaffa, Zainuriah Hassan, M. Asmawi

{"title":"Cinnamomum iners Leaves as an Alternative Therapy for Diabetes","authors":"F. Mustaffa, Zainuriah Hassan, M. Asmawi","doi":"10.3923/AJB.2016.44.52","DOIUrl":"https://doi.org/10.3923/AJB.2016.44.52","url":null,"abstract":"This study was designed to investigate the antidiabetic property of Cinnamomum iners leaves which were used traditionally to combat diabetes. Firstly, the antidiabetic activity of petroleum ether, chloroform, methanol and water extract of C. iners leaves was evaluated. Next, the potential extract which was the methanol extract was fractionated to obtain ethyl acetate, n-butanol, chloroform and aqueous fraction. The active chloroform fraction was subjected to subfractionation process to obtain subfraction 1 (SF 1) and subfraction 2 (SF 2). Cinnamomum iners leaves active portion (methanol extract, chloroform fraction and subfraction 1) was standardized using cinnamic aldehyde. The antidiabetic activity of standardized C. iners leaves was assessed by using Intra-Peritoneal Glucose Tolerance Test (IPGTT). The antidiabetic mechanism of active portion of C. iners leaves were also determined by measuring glucose absorption from the intestine. This study showed significant glucose tolerance effect of active portion of C. iners leaf after repeated oral administration in STZ-induced diabetic rats. The antidiabetic mechanism of subfraction 1 and chloroform fraction of C. iners leaf is by inhibiting glucose absorption from intestine.","PeriodicalId":8510,"journal":{"name":"Asian Journal of Biochemistry","volume":"48 5 1","pages":"44-52"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85866868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Evaluation of Antidepressant like Effects of Ethanolic Hypericum hookerianum and its Glycosidic Flavonoid Enriched Extract in Reserpine Induced Swiss Albino Mice 乙醇金丝桃及其糖苷类黄酮提取物对利血平诱导的瑞士白化小鼠抗抑郁作用的评价

Asian Journal of Biochemistry Pub Date : 2016-01-01 DOI: 10.3923/AJB.2016.1.13

S. Subakanman, S. Murugan, P. Devi

引用次数: 6