Arrhythmia & Electrophysiology Review最新文献_第2页

Who Benefits Most? Patient Selection for Atrial Fibrillation Catheter Ablation in Heart Failure. 谁受益最大？心力衰竭患者心房颤动导管消融的选择。

IF 4.3

Arrhythmia & Electrophysiology Review Pub Date : 2026-05-20 eCollection Date: 2026-01-01 DOI: 10.15420/aer.2025.83

Aaron A Sifuentes, Mohammed Mhanna, Paari Dominic, Peter Farjo

{"title":"Who Benefits Most? Patient Selection for Atrial Fibrillation Catheter Ablation in Heart Failure.","authors":"Aaron A Sifuentes, Mohammed Mhanna, Paari Dominic, Peter Farjo","doi":"10.15420/aer.2025.83","DOIUrl":"10.15420/aer.2025.83","url":null,"abstract":"AF and heart failure (HF) often coexist, amplifying morbidity and mortality. Catheter ablation is an effective rhythm control strategy, particularly in heart failure with reduced ejection fraction, where studies such as CASTLE-AF show improved survival, fewer HF hospitalisations and better quality of life. Evidence in HF with preserved ejection fraction is emerging; RAFT-AF included HF with preserved ejection fraction patients, but showed no significant primary outcome difference, though subgroup data offer insights across the HF spectrum. Procedural risks, influenced by patient frailty and device presence (e.g. left ventricular assist devices and CRT), necessitate careful selection and periprocedural optimisation. Advances in ablation technology, including pulsed field ablation, and adjunctive strategies show promise but require further validation. Early rhythm control, as supported by EAST-AFNET 4, may prevent adverse remodelling and improve outcomes if applied before extensive atrial disease develops. Future directions emphasise multidisciplinary, personalised approaches integrating imaging and biomarkers to optimise patient selection. Thoughtful application of catheter ablation can enhance outcomes in carefully selected HF patients with AF.","PeriodicalId":8412,"journal":{"name":"Arrhythmia & Electrophysiology Review","volume":"15 ","pages":"e21"},"PeriodicalIF":4.3,"publicationDate":"2026-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13284791/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148306788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ablation Methods and Catheter Settings for Ventricular Tachycardia Ablation: A Bench to Bedside Review: Part 2. 室性心动过速消融的消融方法和导管设置：从实验室到床边的回顾：第2部分。

IF 4.3

Arrhythmia & Electrophysiology Review Pub Date : 2026-05-06 eCollection Date: 2026-01-01 DOI: 10.15420/aer.2025.74

Maria Niespialowska-Steuden, John Silberbauer, Jaffar Al-Sheikhli, Rafaella Siang, Joseph Mayer, Tarvinder Dhanjal

引用次数: 0

Device-detected Atrial Fibrillation: How Much is Too Much? 设备检测心房颤动：多少是太多？

IF 4.3

Arrhythmia & Electrophysiology Review Pub Date : 2026-05-06 eCollection Date: 2026-01-01 DOI: 10.15420/aer.2026.04

Jude Scott

{"title":"Device-detected Atrial Fibrillation: How Much is Too Much?","authors":"Jude Scott","doi":"10.15420/aer.2026.04","DOIUrl":"10.15420/aer.2026.04","url":null,"abstract":"Device-detected AF, commonly labelled atrial high-rate episodes or subclinical AF (SCAF), creates a dilemma over anticoagulation: absolute stroke risk will be lowered, yet oral anticoagulation (OAC) carries a real risk of major bleeding. The author argues that searching for a universal episode-duration threshold is not the answer. Analyses of trial results show that baseline SCAF frequency and longest episode duration do not reliably identify a high-risk subgroup nor consistently justify escalation to anticoagulation treatment. Duration-only thresholding is therefore an unstable primary decision-making tool. A practical alternative is proposed: phenotype-led anticoagulation with a burden-led workflow. Phenotypes, especially vascular disease and absolute risk, drive whether OAC is plausibly beneficial; burden determines urgency, monitoring intensity and the need for escalation. This framework primarily addresses SCAF episodes below 24 hours, where clinical uncertainty is greatest and randomised evidence is most directly applicable. It is operationalised as a device-clinic pathway with electrogram adjudication as an entry criterion, burden classes for triage, and phenotype classes for OAC selection, using atrial substrate markers only as tiebreakers in borderline cases.","PeriodicalId":8412,"journal":{"name":"Arrhythmia & Electrophysiology Review","volume":"15 ","pages":"e20"},"PeriodicalIF":4.3,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13187930/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147986120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ablation Methods and Catheter Settings for Ventricular Tachycardia Ablation: A Bench to Bedside Review: Part 1. 室性心动过速消融的消融方法和导管设置：从实验室到床边的回顾：第1部分。

IF 4.3

Arrhythmia & Electrophysiology Review Pub Date : 2026-05-06 eCollection Date: 2026-01-01 DOI: 10.15420/aer.2025.72

Maria Niespialowska-Steuden, John Silberbauer, Jaffar Al-Sheikhli, Rafaella Siang, Joseph Mayer, Tarvinder Dhanjal

{"title":"Ablation Methods and Catheter Settings for Ventricular Tachycardia Ablation: A Bench to Bedside Review: Part 1.","authors":"Maria Niespialowska-Steuden, John Silberbauer, Jaffar Al-Sheikhli, Rafaella Siang, Joseph Mayer, Tarvinder Dhanjal","doi":"10.15420/aer.2025.72","DOIUrl":"10.15420/aer.2025.72","url":null,"abstract":"Catheter ablation is the primary treatment for ventricular tachycardia (VT) in patients with structural heart disease. Unfortunately, its long-term success remains limited. Although mapping techniques have advanced considerably, optimal ablation indices remain essential but less well defined. This two-part comprehensive review bridges the gap between bench and bedside by evaluating methods, technologies, and VT-specific lesion parameters. Here, in part 1, we critically examined conventional and emerging techniques, including radiofrequency (RF), high-power short-duration ablation, temperature-controlled RF. In the accompanying paper, part 2, we focus on bipolar RF ablation, pulsed field ablation and ultra-low-temperature cryoablation, venous ethanol and needle ablation. Despite the growing set of tools available for VT operators, clinical data on the practical and safe creation of lesions remain scarce. The evidence supporting most of the techniques reviewed is limited. We emphasise the need for personalised ablation strategies based on substrate and myocardial anatomy and advocate for the development of future integrated, metric-driven technologies.","PeriodicalId":8412,"journal":{"name":"Arrhythmia & Electrophysiology Review","volume":"15 ","pages":"e18"},"PeriodicalIF":4.3,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13187937/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147986105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Which Patient Benefits from Guideline-directed Medical Therapy for Heart Failure and Rate Control versus Rhythm Control in Patients with Congestive Heart Failure and Atrial Fibrillation and What are Those Therapies? 在充血性心力衰竭和心房颤动患者中，哪些患者受益于心脏衰竭和心率控制与心律控制的药物治疗，这些治疗是什么？

IF 4.3

Arrhythmia & Electrophysiology Review Pub Date : 2026-05-05 eCollection Date: 2026-01-01 DOI: 10.15420/aer.2025.39

Gregory Burkman, Gerald V Naccarelli

引用次数: 0

Radiofrequency Catheter Ablation for Arrhythmia-induced Cardiomyopathy in Infants: A Case Series and Literature Review. 射频导管消融治疗婴儿心律失常引起的心肌病：一个病例系列和文献综述。

IF 4.3

Arrhythmia & Electrophysiology Review Pub Date : 2026-05-01 eCollection Date: 2026-01-01 DOI: 10.15420/aer.2025.63

Xuan Li, Wenjuan Shu, Miao Hou, Haitao Lv, Qiuqin Xu, Bo Wang, Ling Sun, Jiajia Tan, Ye Chen, Wanping Zhou

{"title":"Radiofrequency Catheter Ablation for Arrhythmia-induced Cardiomyopathy in Infants: A Case Series and Literature Review.","authors":"Xuan Li, Wenjuan Shu, Miao Hou, Haitao Lv, Qiuqin Xu, Bo Wang, Ling Sun, Jiajia Tan, Ye Chen, Wanping Zhou","doi":"10.15420/aer.2025.63","DOIUrl":"10.15420/aer.2025.63","url":null,"abstract":"Radiofrequency catheter ablation (RFCA) is an established treatment for paediatric arrhythmias in children weighing >15 kg, yet its role in infants with arrhythmia-induced cardiomyopathy remains less defined. This case series evaluates the efficacy and safety of RFCA in four infants (aged ≤1 year) with arrhythmia-induced cardiomyopathy through a retrospective review of clinical profiles, procedural data and outcomes. All patients had right-sided accessory pathways, with three showing atrioventricular re-entrant tachycardia and one pre-excitation-related cardiomyopathy. Each infant had failed pharmacotherapy, and presented with heart failure and cardiac enlargement. RFCA was successfully performed in all cases without complications. Within 1-6 months postprocedure, both cardiac function and size normalised in every patient. These findings support RFCA as a safe and effective treatment for medically refractory, right-sided, pathway-mediated, arrhythmia-induced cardiomyopathy in infants, highlighting its potential for complete functional recovery.","PeriodicalId":8412,"journal":{"name":"Arrhythmia & Electrophysiology Review","volume":"15 ","pages":"e14"},"PeriodicalIF":4.3,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13187933/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147986250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Management of Idiopathic Outflow Tract Ventricular Arrhythmias. 特发性流出道室性心律失常的治疗。

IF 4.3

Arrhythmia & Electrophysiology Review Pub Date : 2026-05-01 eCollection Date: 2026-01-01 DOI: 10.15420/aer.2025.56

Alan D Enriquez

引用次数: 0

Next-generation ICDs: Individualised Selection for Improved Cardiac Outcomes. 下一代icd：个性化选择改善心脏预后。

IF 4.3

Arrhythmia & Electrophysiology Review Pub Date : 2026-05-01 eCollection Date: 2026-01-01 DOI: 10.15420/aer.2025.61

Lin-Thiri Toon, Christopher Monkhouse, Waqas Ullah, John Paisey

{"title":"Next-generation ICDs: Individualised Selection for Improved Cardiac Outcomes.","authors":"Lin-Thiri Toon, Christopher Monkhouse, Waqas Ullah, John Paisey","doi":"10.15420/aer.2025.61","DOIUrl":"10.15420/aer.2025.61","url":null,"abstract":"Cardiovascular disease is a major global cause of death, with sudden cardiac death accounting for up to half of cases, largely due to ventricular tachyarrhythmias. In the UK, approximately 60,000 out-of-hospital cardiac arrests occur annually, with survival rates of only 2-12%. Younger individuals are also affected, with one cardiac-related death daily in those under 35 years of age. Despite advances in care, arrhythmia recurrence remains high (40-50% within 5 years). ICDs have become pivotal in preventing sudden cardiac death, with continuous innovations in device design, implantation, and arrhythmia detection since their introduction in 1980. Transvenous single-chamber ICDs remain the standard, while dual-chamber and CRT defibrillator devices serve patients needing atrial pacing or heart failure support. Subcutaneous and extravascular ICD systems protect patients not requiring pacing while avoiding lead-related risks. Device selection must be individualised, considering clinical profile, comorbidities, lifestyle, patient preferences, and operator expertise. Ongoing advances, including leadless pacing and modular anti-tachycardia pacing systems, continue to expand personalised device strategies.","PeriodicalId":8412,"journal":{"name":"Arrhythmia & Electrophysiology Review","volume":"15 ","pages":"e15"},"PeriodicalIF":4.3,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13187929/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147986189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mitral Annular Disjunction: Separating the Wheat from the Chaff. 二尖瓣环状分离：将小麦与谷壳分离。

IF 4.3

Arrhythmia & Electrophysiology Review Pub Date : 2026-04-20 eCollection Date: 2026-01-01 DOI: 10.15420/aer.2025.96

Avi Sabbag, Konstantinos C Siontis

引用次数: 0

A Review of Potential Complications of Pulsed Field Ablation for AF: Beneath the Surface. 脉冲场消融治疗心房颤动的潜在并发症综述：表面以下。

IF 4.3

Arrhythmia & Electrophysiology Review Pub Date : 2026-04-20 eCollection Date: 2026-01-01 DOI: 10.15420/aer.2025.54

Francis J Ha, Tai Ermongkonchai, Hui-Chen Han, Nitesh Nerlekar, Adam J Brown, Emily Kotschet

{"title":"A Review of Potential Complications of Pulsed Field Ablation for AF: Beneath the Surface.","authors":"Francis J Ha, Tai Ermongkonchai, Hui-Chen Han, Nitesh Nerlekar, Adam J Brown, Emily Kotschet","doi":"10.15420/aer.2025.54","DOIUrl":"10.15420/aer.2025.54","url":null,"abstract":"Pulsed field ablation (PFA) for AF has changed the landscape of AF treatment globally. While clinical trial data have shown non-inferiority compared with thermal ablation, the safety profile of this technology is still being understood. Large post-approval registry data are now accumulating and have invariably demonstrated that rather than PFA being necessarily safer than conventional thermal ablation, the safety profile is simply different. Pericardial tamponade remains a risk and may even be greater compared with thermal ablation. Coronary artery spasm has been recognised, particularly with off-label use of PFA. Haemolysis and associated acute kidney injury are unique complications related to PFA. Stroke risk persists with likely multiple causes. Other complications, such as femoral venous injury, vagal responses and transient phrenic nerve injury, are increasingly recognised. In this review, we summarise recent data regarding potential complications associated with PFA, including mechanisms, risk factors, management and prevention.","PeriodicalId":8412,"journal":{"name":"Arrhythmia & Electrophysiology Review","volume":"15 ","pages":"e13"},"PeriodicalIF":4.3,"publicationDate":"2026-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13153928/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147866518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0