Arthritis Care & Research最新文献

{"title":"Ageism in Rheumatologic Care: Ensuring Equity and Quality for Older Adults.","authors":"Jiha Lee, Devyani Misra, Una E Makris","doi":"10.1002/acr.25521","DOIUrl":"10.1002/acr.25521","url":null,"abstract":"","PeriodicalId":8406,"journal":{"name":"Arthritis Care & Research","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143596192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"American College of Rheumatology Guidance Statements for Addressing Mental Health Concerns in Youth With Pediatric Rheumatologic Diseases.","authors":"Natoshia R Cunningham, Ashley N Danguecan, Samantha L Ely, Yaa Amponsah, Alaina Davis, Suzanne Edison, Julia Harris, Jordan T Jones, Alana Goldstein-Leever, Alison Manning, Anne McHugh, Crystal Mui, Ekemini Ogbu, Nikki Reitz, Martha Rodriguez, Natalie Rosenwasser, Alyse Tankanow, Erin Treemarcki, Katherine Winner, Tamar B Rubinstein, Andrea M Knight","doi":"10.1002/acr.25519","DOIUrl":"10.1002/acr.25519","url":null,"abstract":"<p><strong>Objective: </strong>Pediatric rheumatologic diseases (PRDs) are characterized by high rates of anxiety and depression known to impact health-related outcomes. We present guidance statements to assess and manage mental health concerns for youth with PRDs in pediatric rheumatology practice.</p><p><strong>Methods: </strong>Development of the guidance statements was initiated in 2019 and concluded in November 2023. It included (1) the formation of a task force (including pediatric rheumatologists, pediatric behavioral health providers, patients, and parents) led by two licensed pediatric psychologists and two board-certified pediatric rheumatologists, (2) iterative drafting of statements and rating of evidence based on the Oxford Centre for Evidence-Based Medicine levels of evidence, (3) an open comment period followed by revision of statements, (4) a Delphi panel process to attain consensus on the statements, and (5) review by the American College of Rheumatology (ACR) Committee on Quality of Care and refinement of statements to an identified list of those with the strongest empiric evidence for endorsement by the ACR.</p><p><strong>Results: </strong>The task force drafted 34 statements for addressing mental health concerns in pediatric rheumatology, including identification, management, and clinic environment/education considerations. After two rounds of Delphi panel voting by a random sample of 76 members of the Childhood Arthritis and Rheumatology Research Alliance, 31 statements attained at least 80% consensus. Eleven of those statements had high empirical support and endorsement and were thus selected as the final guidance statements, including recommendations for depression and anxiety screening in youth aged 12 years and older, management of identified symptoms, and education of patients about mental health.</p><p><strong>Conclusion: </strong>It is a goal that these recommendations be used to empower pediatric rheumatology teams to consider how they may better address mental health concerns in their setting and help improve both mental health- and health-related outcomes for youth with rheumatologic diseases.</p>","PeriodicalId":8406,"journal":{"name":"Arthritis Care & Research","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143571843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global Trends in Risk Factors for Low Back Pain: An Analysis of the Global Burden of Disease Study Data From 1990 to 2021.","authors":"Katharine E Roberts, Manuela L Ferreira, Paula R Beckenkamp, Sneha Nicholson, Lyn March, Paulo H Ferreira","doi":"10.1002/acr.25520","DOIUrl":"10.1002/acr.25520","url":null,"abstract":"<p><strong>Objective: </strong>The increasing burden associated with low back pain (LBP) is a critical issue. This is a novel analysis of trends in risk factors for LBP aiming to identify risk factors that require further attention or consideration in global policies to reduce the burden of LBP.</p><p><strong>Methods: </strong>The Global Burden of Disease study metadata were used to describe the trends in three modifiable categories of risk factors that contribute to the burden associated with LBP. The trends in occupational/ergonomic, behavioral (smoking), and metabolic (high body mass index [BMI]) risk factors for LBP between 1990 and 2021 have been described with attention to global areas, high sociodemographic index (SDI) areas, and low SDI areas.</p><p><strong>Results: </strong>The number of years lived with disability (YLDs) caused by LBP increased globally, in high and low SDI areas between 1990 and 2021. The impact of smoking and occupational/ergonomic risk factors have decreased; however, the impact of high BMI has increased markedly in the same time frame, with a particularly concerning impact in high SDI areas and on women.</p><p><strong>Conclusion: </strong>The burden of LBP is increasing globally, with a significant proportion of the YLDs caused by LBP attributed to three modifiable lifestyle factors: occupation/ergonomics, smoking, and high BMI. Of significant concern is the rapidly increasing impact of high BMI on YLDs caused by LBP, with the greatest impact seen among women in low and high SDI areas. The role of additional risk factors (eg, physical inactivity) still needs to be determined in the context of the global burden of LBP.</p>","PeriodicalId":8406,"journal":{"name":"Arthritis Care & Research","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143571808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rheumatology Medical Education Year in Review, 2023 to 2024.","authors":"Ann Cameron Barr, David Leverenz","doi":"10.1002/acr.25517","DOIUrl":"10.1002/acr.25517","url":null,"abstract":"","PeriodicalId":8406,"journal":{"name":"Arthritis Care & Research","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143565922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Better Patient Care and Team Satisfaction Call for \"Both-And\" Approach.","authors":"Jennifer Brandt, S Sam Lim, Christie M Bartels","doi":"10.1002/acr.25516","DOIUrl":"10.1002/acr.25516","url":null,"abstract":"","PeriodicalId":8406,"journal":{"name":"Arthritis Care & Research","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143536563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of a Telephone-Delivered Walk With Ease Program on Arthritis-Related Symptoms, Function, and Activity: A Randomized Trial.","authors":"Christine A Pellegrini, Sara Wilcox, Yesil Kim, Scott Jamieson, Katherine DeVivo, Daniel Heidtke","doi":"10.1002/acr.25515","DOIUrl":"10.1002/acr.25515","url":null,"abstract":"<p><strong>Objective: </strong>Walk With Ease (WWE) is a six-week arthritis-appropriate evidence-based physical activity program traditionally offered in a face-to-face format. Because many populations encounter participation barriers to in-person programs, WWE was modified for telephone delivery (WWE-T). The short- and long-term effects of this program on physical activity and arthritis-related outcomes were examined.</p><p><strong>Methods: </strong>Participants (n = 267) with arthritis were randomized to WWE-T or a wait list control. WWE-T participants received two telephone calls per week (one group and one individual call) for six weeks. Group calls focused on arthritis education and social support. Individual calls focused on problem-solving and goal setting. Physical function tests, patient-reported outcomes, and physical activity were assessed at baseline, 6 weeks, 6 months, and 12 months.</p><p><strong>Results: </strong>Participants were 92% female and 60% Black and had a mean ± SD age of 64.1 ± 9.4 years and a body mass index of 34.2 ± 7.7. Retention ranged from 93.6% at 6 weeks to 83.8% at 12 months. Participants attended a mean ± SD of 9.8 ± 2.6 calls. At six weeks, WWE-T participants had greater improvements in physical function (P = 0.03), fatigue (P = 0.03), self-efficacy (P ≤ 0.0001), and activity impairment due to health (P = 0.01) as compared to the control group. By 12 months, WWE-T participants had better physical function (P = 0.02), higher arthritis self-efficacy (P ≤ 0.0001), lower depression symptoms (P = 0.02), and lower impairment of daily activities (P = 0.02) than at baseline.</p><p><strong>Conclusion: </strong>A WWE-T program led to improvements in physical function, self-efficacy, and impairment related to daily activities in adults with arthritis. Although changes were not seen in all outcomes, this remotely delivered program may be an effective alternative for adults with arthritis who face barriers to in-person programs.</p>","PeriodicalId":8406,"journal":{"name":"Arthritis Care & Research","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143536566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Are we rheumatologists or just internists who also care for patients with rheumatologically related challenges?: comment on the article by Brandt et al.","authors":"Bruce Rothschild","doi":"10.1002/acr.25518","DOIUrl":"10.1002/acr.25518","url":null,"abstract":"","PeriodicalId":8406,"journal":{"name":"Arthritis Care & Research","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143536561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association Between Metabolic Syndrome and Radiographic Changes in Psoriatic Arthritis: A Cohort Study.","authors":"Fadi Kharouf, Shangyi Gao, S Ercan Tunc, Justine Y Ye, Daniel Pereira, Dafna D Gladman, Vinod Chandran","doi":"10.1002/acr.25513","DOIUrl":"10.1002/acr.25513","url":null,"abstract":"<p><strong>Objective: </strong>Metabolic syndrome (MetS) is a known comorbidity of psoriatic arthritis (PsA) and is associated with PsA disease activity. We aimed to explore the association between MetS and radiographic features (peripheral and axial) in PsA.</p><p><strong>Methods: </strong>We included patients with PsA followed at our prospective observational cohort for the period between 1978 and 2024. We identified patients with MetS on longitudinal follow-up and used generalized estimating equations (GEE) analysis to define the radiographic features independently associated with MetS, adjusting for age, sex, PsA disease duration, calendar decade, and use of targeted disease-modifying antirheumatic drugs.</p><p><strong>Results: </strong>The study population consisted of 1,422 patients, out of which 400 (28.1%) had MetS at baseline (clinic entry) and 836 (58.79%) had a record of MetS (per the harmonized definition) over a median follow-up duration of 10.59 (interquartile range 4.52-18.28) years. The mean (SD) age of our cohort at baseline was 44.43 (12.98) years, with 789 patients (55.5%) identifying as men. Mean (SD) body mass index was 28.79 (6.36) kg/m². In the GEE analysis, MetS was not significantly associated with axial disease or radiographic damage to peripheral joints, assessed as the presence of syndesmophytes or sacroiliitis and the radiographic damaged joint count, respectively. On the other hand, MetS was significantly associated with calcaneal spurs, diffuse idiopathic skeletal hyperostosis, and degenerative disc disease.</p><p><strong>Conclusion: </strong>MetS is associated with degenerative and metabolic changes in the spine and entheses but not with radiographic damage in PsA.</p>","PeriodicalId":8406,"journal":{"name":"Arthritis Care & Research","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143536578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sequence Analysis to Phenotype Health Care Patterns in Adults With Musculoskeletal Conditions Using Primary Care Electronic Health Records.","authors":"Smitha Mathew, George Peat, Emma Parry, Ross Wilkie, Kelvin P Jordan, Jonathan C Hill, Dahai Yu","doi":"10.1002/acr.25514","DOIUrl":"10.1002/acr.25514","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to apply sequence analysis (SA) to phenotype health care patterns of adult patients with musculoskeletal (MSK) conditions using primary care electronic health records and to investigate the association between these health care patterns and patients' self-reported outcomes after consultation.</p><p><strong>Methods: </strong>Data from the Multilevel Integrated Data for musculoskeletal health intelligence and Actions program conducted in North Staffordshire and Stoke-on-Trent, United Kingdom, was used. The study included patients aged ≥18 years who consulted primary care for MSK conditions between September 2021 and July 2022. SA was employed to categorize patients with similar health care patterns in primary care in the five years before their index consultation in respect to consultations, analgesic prescriptions, imaging, physiotherapy, and secondary care referrals. Associations of sociodemographic characteristics and self-reported outcome with clusters were determined.</p><p><strong>Results: </strong>In total, 1,875 patients consulting primary care for MSK conditions were available for analysis. SA identified five clusters of previous health care patterns among patients with MSK conditions, including \"increasing consultation and analgesia\" (5.60%), \"low consultation and health care use\" (57.39%), \"high consultation and health care use\" (8.32%), \"low consultation but high analgesia\" (13.01%), and \"low consultation but moderate health care use\" (15.68%). Patients in the \"high consultation and health care use\" group were predominantly female, were older, had obesity, had more comorbidities, and lived in the most deprived areas compared to those in the \"low consultation and health care use\" group. Additionally, self-reported outcomes varied significantly among clusters, with patients in the \"high consultation and health care use\" group reporting worse self-reported outcomes.</p><p><strong>Conclusion: </strong>This analysis identified five distinct clusters of health care patterns for patients with MSK conditions in primary care and observed substantial variations in patients' self-reported outcomes and sociodemographic profiles across these different groups of patients.</p>","PeriodicalId":8406,"journal":{"name":"Arthritis Care & Research","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143536576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sex-Related Differences in Efficacy and Safety Outcomes in Axial Spondyloarthritis Randomized Clinical Trials: A Systematic Literature Review and Meta-Analysis.","authors":"Angel Gao, Jordi Pardo Pardo, Steven Dang, Lianne S Gensler, Philip Mease, Lihi Eder","doi":"10.1002/acr.25512","DOIUrl":"10.1002/acr.25512","url":null,"abstract":"<p><strong>Objective: </strong>We aimed to assess differences in baseline characteristics, efficacy, and safety of advanced therapies between male and female patients with axial spondyloarthritis (axSpA) in randomized controlled trials (RCTs).</p><p><strong>Methods: </strong>We conducted a systematic literature search for RCTs assessing the efficacy of advanced therapies in patients with axSpA until March 19, 2023. We extracted the following outcomes by sex: baseline participant characteristics, Assessment in Spondylarthritis International Society (ASAS) 20/40 criteria, and Axial Spondyloarthritis Disease Activity Score low disease activity or inactive disease (ASDAS-LDA/ID). Random-effects models were used to calculate pooled effects for responses in men versus women for different medication classes.</p><p><strong>Results: </strong>We included 79 RCTs (n = 23,748 patients, 69.7% male). Only 9 trials (11.4%), 22 trials (28%), and 9 trials (11.4%) reported baseline characteristics, efficacy end points, and safety end points by sex, respectively. At baseline, women were significantly older and had higher pain scores, whereas men had higher C-reactive protein levels. Overall, male patients were more likely to achieve an ASAS40 response compared to female patients for all advanced therapies (odds ratio [OR] 1.88, 95% confidence interval [CI] 1.44-2.46) and for interleukin-17A (IL-17A) inhibitors (IL-17Ai) (OR 1.82) and tumor necrosis factor inhibitor (TNFi) (OR 2.42), and male patients had numerically higher values for IL-17A/Fi. Male patients were also more likely to achieve an ASDAS-LDA/ID (OR 2.19, 95% CI 1.47-3.26) across all advanced therapies and for IL-17Ai (OR 2.08) and TNFi (OR 2.42) individually.</p><p><strong>Conclusion: </strong>Female patients with axSpA are less likely to achieve efficacy outcomes on advanced therapies compared to their male counterparts, with similar differences across medication classes. Future studies should study the biologic (sex-related) and sociocultural (gender-related) mechanisms underlying these differences.</p>","PeriodicalId":8406,"journal":{"name":"Arthritis Care & Research","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143481976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}