Archives of Environmental Contamination and Toxicology最新文献

{"title":"Transport Behavior of Cd2+ in Highly Weathered Acidic Soils and Shaping in Soil Microbial Community Structure","authors":"Jiaxin Shi,&nbsp;Luhua Jiang,&nbsp;Jiejie Yang,&nbsp;Ziwen Guo,&nbsp;Kewei Li,&nbsp;Yulong Peng,&nbsp;Nazidi Ibrahim,&nbsp;Hongwei Liu,&nbsp;Yili Liang,&nbsp;Huaqun Yin,&nbsp;Xueduan Liu","doi":"10.1007/s00244-023-01046-6","DOIUrl":"10.1007/s00244-023-01046-6","url":null,"abstract":"<div><p>The mining and smelting site soils in South China present excessive Cd pollution. However, the transport behavior of Cd in the highly weathered acidic soil layer at the lead–zinc smelting site remains unclear. Here, under different conditions of simulated infiltration, the migration behavior of Cd²⁺ in acid smelting site soils at different depths was examined. The remodeling effect of Cd²⁺ migration behavior on microbial community structure and the dominant microorganisms in lead–zinc sites soils was analyzed using high-throughput sequencing of 16S rRNA gene amplicons. The results revealed a specific flow rate in the range of 0.3–0.5 mL/min that the convection and dispersion have no obvious effect on Cd²⁺ migration. The variation of packing porosity could only influence the migration behavior by changing the average pore velocity, but cannot change the adsorption efficiency of soil particles. The Cd has stronger migration capacity under the reactivation of acidic seepage fluid. However, in the alkaline solution, the physical properties of soil, especially pores, intercept the Cd compounds, further affecting their migration capacity. The acid-site soil with high content of SOM, amorphous Fe oxides, crystalline Fe/Mn/Al oxides, goethite, and hematite has stronger ability to adsorb and retain Cd²⁺. However, higher content of kaolinite in acidic soil will increase the potential migration of Cd²⁺. Besides, the migration behavior of Cd²⁺ results in simplified soil microbial communities. Under Cd stress, Cd-tolerant genera (<i>Bacteroides</i>, <i>Sphingomonas</i>, <i>Bradyrhizobium</i>, and <i>Corynebacterium</i>) and bacteria with both acid-Cd tolerance (<i>WCHB 1-84)</i> were distinguished. The <i>Ralstonia</i> showed a high enrichment degree in alkaline Cd²⁺ infiltration solution (pH 10.0). Compared to the influence of Cd²⁺ stress, soil pH had a stronger ability to shape the microbial community in the soil during the process of Cd²⁺ migration.</p></div>","PeriodicalId":8377,"journal":{"name":"Archives of Environmental Contamination and Toxicology","volume":"86 1","pages":""},"PeriodicalIF":3.7,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138795138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ivermectin Toxicokinetics in Rainbow Trout (Oncorhynchus mykiss) following P-glycoprotein Induction","authors":"Vinicius Cavicchioli Azevedo,&nbsp;Christina U. Johnston,&nbsp;Christopher J. Kennedy","doi":"10.1007/s00244-023-01045-7","DOIUrl":"10.1007/s00244-023-01045-7","url":null,"abstract":"<div><p>Alterations in ivermectin (IVM, 22,23-dihydro avermectin B1a+22,23-dihydro avermectin B1b) toxicokinetics following P-glycoprotein (P-gp) induction by clotrimazole (CTZ) were examined in rainbow trout (<i>Oncorhynchus</i> mykiss) to assess the potential importance of P-gp activity levels in xenobiotic distribution and kinetics in fish. Control and fish pretreated with CTZ (30 µmol/kg) were administered 175 µg/kg ³H-IVM into the caudal vasculature. At various time points (0.25, 0.5, 1, 3, 24, 48, 96, and 168 h) following injection, tissues (blood, liver, kidney, gill, intestines, brain [5 regions], eye, gonad and fat) were removed analyzed for IVM-derived radioactivity. IVM concentration declined in blood, liver, kidney and gill, and concentrations in other tissues remained constant over the sampling period. The highest measured concentrations were found in kidney, followed by liver, with the lowest values found in brain, eye and gonad. The highest % of the administered dose was found in the liver and kidney in the immediate hours post-administration, and in the intestines and fat at 24 h post-administration. P-gp induction by CTZ did not alter IVM distribution or any calculated toxicokinetic parameter (AUC, mean residence time, T_1/2, clearance rate, volume of distribution), suggesting that P-gp induction may be limited or that P-gp plays a lesser role in xenobiotic kinetics in fish compared to mammals.</p></div>","PeriodicalId":8377,"journal":{"name":"Archives of Environmental Contamination and Toxicology","volume":"86 1","pages":""},"PeriodicalIF":3.7,"publicationDate":"2023-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138795117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contamination of Soil by Obsolete Pesticide Stockpiles: A Case Study of Derince Province, Turkey","authors":"Perihan Binnur Kurt-Karakus,&nbsp;Mustafa Odabasi,&nbsp;Askin Birgul,&nbsp;Baris Yaman,&nbsp;Ersan Gunel,&nbsp;Yetkin Dumanoglu,&nbsp;Liisa Jantunen","doi":"10.1007/s00244-023-01043-9","DOIUrl":"10.1007/s00244-023-01043-9","url":null,"abstract":"<div><p>The areal distributions of the soil organochlorine pesticide (OCP) levels were investigated at adjacent and surrounding sites of the obsolete pesticide stockpile warehouse in Kocaeli, Türkiye. OCP levels in soil at neighboring sampling locations (positioned at 0.4 to 3 km from the stockpile) varied from 0.4 to 9 µg/kg and 4.2 to 2226 µg/kg (dry weight) for ΣHCHs and ΣDDXs, respectively. Levels at adjacent locations (positioned within 20 m from the stockpile) were considerably higher, varying from 74 to 39,619 µg/kg and 1592 to 30,419 µg/kg for ΣHCHs and ΣDDXs, respectively. Levels of OCPs dropped abruptly with the horizontal distance from the stockpile and had different transect profiles. The enantiomer fractions (EFs) near the stockpile range from 0.494 to 0.521, 0.454 to 0.515, and 0.483 to 0.533 for <i>α</i>-HCH, <i>o,p</i>′-DDT, and <i>o,p</i>′-DDD, respectively. These near-racemic EFs suggested that observed soil OCP levels were mainly influenced by recent emissions from the stockpile. A comparison of OCP compositions observed in the soil at the present study with the technical HCHs and DDTs revealed that the material in the stockpile primarily contains byproducts that were discarded during DDT and Lindane production at the adjacent plant instead of their technical mixtures.</p></div>","PeriodicalId":8377,"journal":{"name":"Archives of Environmental Contamination and Toxicology","volume":"86 1","pages":""},"PeriodicalIF":3.7,"publicationDate":"2023-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138588495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Annona glabra L. Seeds: An Agricultural Waste Biosorbent for the Eco-Friendly Removal of Methylene Blue","authors":"Le-Thuy-Thuy-Trang Hoang,&nbsp;Hoang-Vinh-Truong Phan,&nbsp;Phuong-Nam Nguyen,&nbsp;Thanh-Truc Dang,&nbsp;Thanh-Nha Tran,&nbsp;Duc-Thuong Vo,&nbsp;Van-Kieu Nguyen,&nbsp;Minh-Trung Dao","doi":"10.1007/s00244-023-01044-8","DOIUrl":"10.1007/s00244-023-01044-8","url":null,"abstract":"<div><p>The seeds of <i>Annona glabra</i> L., an invasive plant in Vietnam, were first employed as a new biosorbent for the adsorption of methylene blue (MB) from aqueous media. The characterizations of the material using FT-IR, SEM, nitrogen adsorption–desorption analysis, and point of zero charge reveals that it possesses a rough and irregular surface, various polar functional groups, and pH_pzc of 5.5. Certain adsorption conditions including adsorbent dose, solution pH, contact time, and initial concentration of MB were found to affect adsorption efficiency. The kinetic data are well fitted with pseudo-second-order model with the adsorption rate of 0.002 g mg⁻¹ min⁻¹ and initial rate of 4.46 mg g⁻¹ min⁻¹. For the adsorption isotherm, three nonlinear models were used to analyze the experiment data, including Langmuir, Freundlich, and Temkin. The results indicate that the Langmuir model best describes the adsorption of <i>Annona glabra</i> L. seeds powder (AGSP) with a maximum adsorption capacity of 98.0 mg g⁻¹. The investigation underpins the adsorption mechanism, whereby the electrostatic attraction between positively charged MB and negatively charged surface of AGSP is expected to be the predominant mechanism, together with hydrogen bonding and pi–pi interaction. These results make AGSP an interesting biosorbent concerning its environmental friendliness, cost-effectiveness, and relatively high dye adsorption capacity.</p></div>","PeriodicalId":8377,"journal":{"name":"Archives of Environmental Contamination and Toxicology","volume":"86 1","pages":""},"PeriodicalIF":3.7,"publicationDate":"2023-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138588125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adult Mosquito and Butterfly Exposure to Permethrin and Relative Risk Following ULV Sprays from a Truck-Mounted Sprayer","authors":"Timothy A. Bargar,&nbsp;Yongxing Jiang","doi":"10.1007/s00244-023-01022-0","DOIUrl":"10.1007/s00244-023-01022-0","url":null,"abstract":"<div><p>Ground applications of adulticides via a specialized truck-mounted sprayer are one of the most common practices for control of flying adult mosquitoes. Aerosols released to drift through a targeted area persist in the air column to contact and kill flying mosquitoes, but may also drift into adjacent areas not targeted by the applications where it may affect nontarget insects such as imperiled butterflies. This study compared the risk of permethrin to adult mosquitoes and adult butterflies to assess the likelihood that the butterflies would be affected following such sprays. Permethrin toxicity values were determined for <i>Aedes aegypti</i> and <i>Culex quinquefasciatus</i> (LD50s of 81.1 and 166.3 ng/g dw, respectively) and then combined with published toxicity data in a species sensitivity distribution for comparison with published permethrin toxicity data for adult butterflies. The sensitivity distributions indicated adult butterflies and mosquitoes are similarly sensitive, meaning relative risk would be a function of exposure. Exposure of adult butterflies and adult mosquitoes to permethrin was measured following their exposure to ULV sprays in an open field. Average permethrin concentrations on adult mosquitoes (912–38,061 ng/g dw) were typically an order of magnitude greater than on adult butterflies (110–11,004 ng/g dw) following each spray, indicating lower risk for butterflies relative to mosquitoes. Despite lower estimated risk, 100% mortality of adult butterflies occurred following some of the sprays. Additional studies could help understand exposure and risk for butterflies in densely vegetated habitats typical near areas treated by ULV sprays.</p></div>","PeriodicalId":8377,"journal":{"name":"Archives of Environmental Contamination and Toxicology","volume":"86 1","pages":""},"PeriodicalIF":3.7,"publicationDate":"2023-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s00244-023-01022-0.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138591532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation the Toxicity of Heavy Metal Mixtures in Anecic Earthworms (Aporrectodea giardi)","authors":"Hadia Benhalima,&nbsp;Hana Sbartai,&nbsp;Ibtissem Sbartai","doi":"10.1007/s00244-023-01034-w","DOIUrl":"10.1007/s00244-023-01034-w","url":null,"abstract":"<div><p>Using earthworms as bioindicators of heavy metal contamination in soils is a relevant tool for environmental risk monitoring. This study examines the combined effects of four distinct concentrations mixtures (<i>M</i>1, <i>M</i>2, <i>M</i>3 and <i>M</i>4) containing Cd, Cr, Cu, Ni, Fe and Mn on <i>Aporrectodea giardi</i> earthworms after 12 and 24 days (12 D/24 D) of exposure via the monitoring of certain biomarkers of stress including total protein content, glutathione (GSH), metallothionein (MT), catalase and lipoxygenase (LOX) activities. The results show a decrease in the total protein level for the <i>M</i>3 mixture after 24 D, whereas it increases for all other treatments regardless of exposure time. Glutathione and metallothionine levels increased for <i>M</i>2 and <i>M</i>3 and decreased for <i>M</i>1 and <i>M</i>4 after 12 D; they increased after 24 D for all the mixtures. Regarding enzyme activities, catalase activity was decreased for all the treatments unless for <i>M</i>3 (<i>P</i> &gt; 0.05). However, LOX increased for <i>M</i>1, <i>M</i>2 and <i>M</i>4 except for <i>M</i>3 after 12 D, when inhibition of this biomarker was observed. LOX activity was inhibited for all the mixtures at the end of the treatment. All the mixtures generated oxidative stress in <i>Aporrectodea giard</i>i, which is minimized by increasing MT levels to remove the metal ions and triggering the antioxidant system, composed primarily of GSH and LOX to restore cellular homeostasis. These findings suggest that the species <i>Aporrectodea giardi</i> could be an excellent candidate for ecotoxicological risk assessment of soils contaminated by metal mixtures and it can be used in bioremediation for its fitness which allows it to tolerate high concentrations of metal mixtures.</p></div>","PeriodicalId":8377,"journal":{"name":"Archives of Environmental Contamination and Toxicology","volume":"86 1","pages":""},"PeriodicalIF":3.7,"publicationDate":"2023-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136395938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microplastics Distribution in Sediments Collected from Myanmar","authors":"Thant Zin Tun,&nbsp;Ei Ei Mon,&nbsp;Haruhiko Nakata","doi":"10.1007/s00244-023-01042-w","DOIUrl":"10.1007/s00244-023-01042-w","url":null,"abstract":"<div><p>Microplastics (MPs) distributions have been increasingly reported in the terrestrial areas worldwide, but little information is available for ASEAN regions. In this study, 68 sediment samples of drainage channels, lakes, rivers and beaches from Myanmar were collected between 2014 and 2018, and analyzed to investigate the status of MPs concentration and prevalence. The high concentrations of MPs in sediments were found in urban cities called Yangon (13,855 pieces/kg dry weight), Mandalay (11,946 pieces/kg), and Pathein (12,583 pieces/kg), which were two orders of magnitude greater than the MPs concentrations in sediments collected in rural towns called Wundwin. These results suggested that the difference in high population densities and high municipal solid waste generation rates are related to the MPs contamination in sediments. Polyethylene, polypropylene and polyethylene terephthalate with fragments, lines/fibers and films/sheets were major polymers and shape in the sediment samples analyzed from Myanmar. To our knowledge, this is the first study to report the distribution of MPs in sediments from Myanmar.</p></div>","PeriodicalId":8377,"journal":{"name":"Archives of Environmental Contamination and Toxicology","volume":"86 1","pages":""},"PeriodicalIF":3.7,"publicationDate":"2023-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71477475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Food Web Structures and Mercury Exposure Pathway to Fish in Minamata Bay","authors":"Kenji Yoshino,&nbsp;Katsumasa Yamada,&nbsp;Gen Kanaya,&nbsp;Tomohiro Komorita,&nbsp;Kai Okamoto,&nbsp;Masaatsu Tanaka,&nbsp;Yuya Tada,&nbsp;Yasuhisa Henmi,&nbsp;Megumi Yamamoto","doi":"10.1007/s00244-023-01040-y","DOIUrl":"10.1007/s00244-023-01040-y","url":null,"abstract":"<div><p>We analyzed total mercury content (THg) and carbon (<i>δ</i>¹³C) and nitrogen (<i>δ</i>¹⁵N) stable isotope ratios in fish, subtidal macrobenthos, and particulate organic matter (POM) as a proxy for pelagic phytoplankton and attached microalgae as a proxy for microphytobenthos to investigate the mercury exposure pathway in fish. For four seasons, samples of the above-mentioned organisms were collected on five occasions (July and October 2018 and January, April, and July 2019) in Minamata Bay. Isotope analysis showed that Minamata Bay food web structures were almost entirely fueled by microphytobenthos. The THg values of the fish and macrobenthos species were positively correlated with their <i>δ</i>¹³C. This indicates that their diets, which were highly fueled by microphytobenthos, led to high THg bioaccumulation in both macrobenthos and fish. The feeding habits of fishes differ depending on the species, and they prey on organisms of many taxa, including fish (mainly Japanese anchovy), crabs, shrimp, copepods, annelids, and algae. Fish species that preyed on benthic crustaceans had high THg. These results suggest that the main pathway of Hg bioaccumulation in fish from Minamata Bay is the benthic food chain, which is primarily linked to benthic crustaceans fueled by microphytobenthos.</p></div>","PeriodicalId":8377,"journal":{"name":"Archives of Environmental Contamination and Toxicology","volume":"85 4","pages":"360 - 373"},"PeriodicalIF":4.0,"publicationDate":"2023-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71420251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current Status of Antifouling Biocides Contamination in the Seto Inland Sea, Japan","authors":"Hiroya Harino,&nbsp;Madoka Ohji,&nbsp;Kumiko Kono,&nbsp;Toshimitsu Onduka,&nbsp;Takashi Hano,&nbsp;Kazuhiko Mochida","doi":"10.1007/s00244-023-01036-8","DOIUrl":"10.1007/s00244-023-01036-8","url":null,"abstract":"<div><p>A monitoring survey of antifouling biocides was conducted in the Harima Nada Sea and Osaka Bay of the Seto Inland Sea, Japan to assess contamination by organotin (OT) compounds and alternative biocides. The concentrations of tributyltin (TBT) compounds in surface water ranged from 1.0 to 2.8 ng/L, and the detected TBT concentrations in the bottom water layer were higher than those in the surface water. The concentrations of TBT compounds in sediment samples ranged from 2.0 to 28 ng/g dry weight (dw), respectively. The concentrations of alternative biocides in the water and sediment were lower than those before the banning of TBT by the International Maritime Organization (IMO). Although triphenyltin (TPT) compounds were not detected in water samples, TPT compounds were detected in the range of &lt; 0.1–2700 ng/g dw in sediment samples. Their concentrations in the water samples were as follows: diuron, &lt; 1–53 ng/L; Sea-Nine 211, &lt; 1–1.8 ng/L; Irgarol 1051, &lt; 1–4.0 ng/L; dichlofluanid, &lt; 1–343 ng/L; and chlorothalonil, &lt; 1–1 ng/L, and the ranges of these alternative compounds in sediment samples were diuron, 32–488 ng/g dw; Sea-Nine 211, 47–591 ng/g dw; Irgarol, 33–128 ng/g dw; dichlofluanid, 67–8038 ng/g dw; and chlorothalonil, 31–2975 ng/g dw. Thus, the OTs and alternative biocides have still been detected in water and sediment samples from closed sea areas.</p></div>","PeriodicalId":8377,"journal":{"name":"Archives of Environmental Contamination and Toxicology","volume":"85 4","pages":"333 - 348"},"PeriodicalIF":4.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71420249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dietary Uptake of Highly Hydrophobic Chemicals by Rainbow Trout (Oncorhynchus Mykiss)","authors":"Lawrence P. Burkhard,&nbsp;Tylor J. Lahren,&nbsp;Kaila B. Hanson,&nbsp;Alex J. Kasparek,&nbsp;David R. Mount","doi":"10.1007/s00244-023-01038-6","DOIUrl":"10.1007/s00244-023-01038-6","url":null,"abstract":"<div><p>Rainbow trout (<i>Oncorhynchus mykiss</i>) was exposed through the diet to a mixture of non-ionic organic chemicals for 28 d, followed by a depuration phase, in accordance with OECD method 305. The mixture included hexachlorobenzene (HCB), 2,2′,5,5′-tetrachlorobiphenyl (PCB-52), 2,2′,5,5′-hexachlorobiphenyl (PCB-153), decachlorobiphenyl (PCB-209), decabromodiphenyl ether (BDE209), decabromodiphenyl ethane (DBDPE), bis-(2-ethylhexyl)-3,4,5,6-tetrabromophthalate (TBPH), perchloro-p-terphenyl (p-TCP), perchloro-m-terphenyl (m-TCP), and perchloro-p-quaterphenyl (p-QTCP), the latter six of which are considered highly hydrophobic based on n-octanol/water partition coefficients (<i>K</i>_OW) greater than 10⁸. All chemicals had first-order uptake and elimination kinetics except p-QTCP, whose kinetics could not be verified due to limitations of analytical detection in the elimination phase. For HCB and PCBs, the growth-corrected elimination rates (<i>k</i>_2<i>g</i>), assimilation efficiencies (<i>α</i>), and biomagnification factors (BMF_L) corrected for lipid content compared well with literature values. For the highly hydrophobic chemicals, elimination rates were faster than the rates for HCB and PCBs, and <i>α</i>’s and BMF_Ls were much lower than those of HCB and PCBs, i.e., ranging from 0.019 to 2.8%, and from 0.000051 to 0.023 (g-lipid/g-lipid), respectively. As a result, the highly hydrophobic organic chemicals were found be much less bioavailable and bioaccumulative than HCB and PCBs. Based on the current laboratory dietary exposures, none of the highly hydrophobic substances would be expected to biomagnify, but Trophic Magnification Factors (TMFs) &gt; 1 have been reported from field studies for TBPH and DBDPE. Additional research is needed to understand and reconcile the apparent inconsistencies in these two lines of evidence for bioaccumulation assessment.</p></div>","PeriodicalId":8377,"journal":{"name":"Archives of Environmental Contamination and Toxicology","volume":"85 4","pages":"390 - 403"},"PeriodicalIF":4.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71420250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}