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Post-traumatic Gradenigo syndrome: an uncommon complication in the antibiotic era? 创伤后格雷迪尼戈综合征：抗生素时代的罕见并发症？
IF 0.5 4区 医学
Archivos argentinos de pediatria Pub Date : 2026-07-31 Epub Date: 2026-01-22 DOI: 10.5546/aap.2025-10848.eng
Leidy D Ballén Pinilla, María V Suárez, Claudia Quijano
{"title":"Post-traumatic Gradenigo syndrome: an uncommon complication in the antibiotic era?","authors":"Leidy D Ballén Pinilla, María V Suárez, Claudia Quijano","doi":"10.5546/aap.2025-10848.eng","DOIUrl":"10.5546/aap.2025-10848.eng","url":null,"abstract":"<p><p>Gradenigo syndrome (GS) is a rare complication of otitis media, secondary to infection spreading to the petrous apex, with potential involvement of cranial nerves V and VI. We present the unusual case of a previously healthy 5-year-old boy who developed GS after a penetrating trauma to the left ear caused by a schoolmate. The patient presented severe ear pain, purulent otorrhea, and horizontal diplopia with VI cranial nerve palsy and hemifacial hypoesthesia. CT showed petrous bone erosion, and MRI showed meningeal enhancement without abscesses. Antibiotic therapy and transtympanic ventilation tubes were placed, with complete clinical resolution. This case illustrates a rarely reported trigger of GS in pediatrics, highlighting the importance of considering this entity in complicated post-traumatic otitis, where early clinical suspicion, a multidisciplinary approach, and the timely use of imaging studies were decisive for a successful outcome.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202510848"},"PeriodicalIF":0.5,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146008559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Entropy reduction and F-score: Applications of information theory in diagnostic test evaluation. 熵降与f分：信息论在诊断测试评估中的应用。
IF 0.5 4区 医学
Archivos argentinos de pediatria Pub Date : 2026-07-31 Epub Date: 2026-03-26 DOI: 10.5546/aap.2025-10882.eng
Eduardo Cuestas, María E Cieri, L Johana Escobar Zuluaga, María M Ruiz Brünner
{"title":"Entropy reduction and F-score: Applications of information theory in diagnostic test evaluation.","authors":"Eduardo Cuestas, María E Cieri, L Johana Escobar Zuluaga, María M Ruiz Brünner","doi":"10.5546/aap.2025-10882.eng","DOIUrl":"10.5546/aap.2025-10882.eng","url":null,"abstract":"<p><p>This paper proposes an approach based on information theory and machine learning, applying the F-score and entropy reduction to analyze the flow of information among the patient, the diagnostic test used to evaluate the disease, and the evaluators who interpret the results, thereby enriching the critical assessment of diagnostic tests. The F-score, by integrating positive predictive value and sensitivity, offers a synthetic measure that is less dependent on prevalence. Entropy reduction is a comprehensive metric that quantifies the decrease in uncertainty and informational gain of a diagnostic test, allowing accurate comparisons between different tests using a single measure of accuracy. For practical application, we designed a specific calculator that integrates these indicators. Its implementation would facilitate the interpretation of diagnostic studies and improve clinical decision-making.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202510882"},"PeriodicalIF":0.5,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147502583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Use of cryobiopsy for diagnosis and treatment of a rare laryngeal tumor in pediatrics. 低温活检在儿科罕见喉部肿瘤诊断和治疗中的应用。
IF 0.5 4区 医学
Archivos argentinos de pediatria Pub Date : 2026-07-31 Epub Date: 2026-03-19 DOI: 10.5546/aap.2025-10901.eng
Rubén Ferraz, Cintia Antonioli, Ivanna Boalichuk
{"title":"Use of cryobiopsy for diagnosis and treatment of a rare laryngeal tumor in pediatrics.","authors":"Rubén Ferraz, Cintia Antonioli, Ivanna Boalichuk","doi":"10.5546/aap.2025-10901.eng","DOIUrl":"10.5546/aap.2025-10901.eng","url":null,"abstract":"<p><p>This report highlights the importance of differential diagnosis of laryngeal obstructive airway pathologies, as well as the growing value of endoscopic techniques, such as cryobiopsy, in achieving a definitive, accurate diagnosis. This is an 8-month-old infant who presented with signs of airway obstruction and a history consistent with foreign body aspiration. During endoscopy under general anesthesia, a supraglottic tumor was observed, which was resected using a cryobiopsy probe, a method that is not widely used in pediatrics and in our setting. Postoperative pathological anatomy confirmed the diagnosis of juvenile xanthogranuloma, a form of non-Langerhans cell histiocytosis with an uncommon location in the larynx.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202510901"},"PeriodicalIF":0.5,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147472477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Infantile bullous pemphigoid refractory to corticosteroids: Response to cyclosporine. 皮质类固醇难治性婴儿大疱性类天疱疮：对环孢素的反应。
IF 0.5 4区 医学
Archivos argentinos de pediatria Pub Date : 2026-07-31 Epub Date: 2026-05-14 DOI: 10.5546/aap.2025-10905.eng
Lucía Scillama, Natalia Mantero, Laura Caristia, Martín Loriente, Patricia Della Giovanna
{"title":"Infantile bullous pemphigoid refractory to corticosteroids: Response to cyclosporine.","authors":"Lucía Scillama, Natalia Mantero, Laura Caristia, Martín Loriente, Patricia Della Giovanna","doi":"10.5546/aap.2025-10905.eng","DOIUrl":"10.5546/aap.2025-10905.eng","url":null,"abstract":"<p><p>Bullous pemphigoid is a common autoimmune bullous skin disease in elderly patients, but it is rare in children. We present the case of a 4-month-old boy diagnosed with bullous pemphigoid that was refractory to conventional treatment, who achieved remission after 2 weeks of treatment with cyclosporine without experiencing any adverse effects.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202510905"},"PeriodicalIF":0.5,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147925947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Psychosocial risk in pediatric cancer patients and the perceived usefulness of available care resources by their caregivers. 儿童癌症患者的心理社会风险及其护理人员对现有护理资源的感知有用性
IF 0.5 4区 医学
Archivos argentinos de pediatria Pub Date : 2026-07-31 Epub Date: 2026-05-21 DOI: 10.5546/aap.2025-10940.eng
Débora Farberman, Ignacio Goldsmit, Bárbara Zima, Valentina Cantón, Soledad Lacava, Sol Couselo, Ruth Páez, Florencia Peralta
{"title":"Psychosocial risk in pediatric cancer patients and the perceived usefulness of available care resources by their caregivers.","authors":"Débora Farberman, Ignacio Goldsmit, Bárbara Zima, Valentina Cantón, Soledad Lacava, Sol Couselo, Ruth Páez, Florencia Peralta","doi":"10.5546/aap.2025-10940.eng","DOIUrl":"10.5546/aap.2025-10940.eng","url":null,"abstract":"<p><p>Introduction. Pediatric cancer exposes families to numerous chronic stressors, which require resources that are often lacking in vulnerable settings. Objectives. To assess the psychosocial risk among pediatric cancer patients and to explore caregivers' perceptions of the usefulness of the psychosocial support services offered by hospitals. Population and methods. This was an observational, prospective, descriptive, cross-sectional study. The study included caregivers of patients with a recent cancer diagnosis from five Argentine hospitals. Participants were administered the Psychosocial Assessment Tool (PAT) questionnaire and a hospital psychosocial intervention inventory designed for this study. Results. The sample consisted of 103 subjects. Public and private hospitals obtained similar risk scores. Average risk: moderate. The sample was distributed as follows: low risk (43%), moderate risk (41%), and high risk (16%). The areas of highest risk were family structure and resources, stress response, and parental problems. All institutional measures aimed at strengthening financial resources were reported as highly helpful. The choice of other types of interventions varied, with particular emphasis on the usefulness of those directed at patients and at strengthening social support. Interventions aimed at treating caregiver psychopathology were considered less useful, despite this type of problem being one of the most prevalent among parents at high and moderate psychosocial risk. Conclusion. This study assessed the psychosocial risk among pediatric cancer patients in Argentina, identified the psychosocial interventions offered by hospitals, and examined caregivers' perceptions of the usefulness of these interventions during the first month following diagnosis.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202510940"},"PeriodicalIF":0.5,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147970086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antiglomerular basement membrane disease (Goodpasture syndrome) associated with ANCAnegative central nervous system vasculitis. 与anco阴性中枢神经系统血管炎相关的抗肾小球基底膜病（good牧草综合征）。
IF 0.5 4区 医学
Archivos argentinos de pediatria Pub Date : 2026-07-31 Epub Date: 2026-01-15 DOI: 10.5546/aap.2025-10816.eng
Bárbara Cosentino, Anabella Spierer, Florencia Gorjón
{"title":"Antiglomerular basement membrane disease (Goodpasture syndrome) associated with ANCAnegative central nervous system vasculitis.","authors":"Bárbara Cosentino, Anabella Spierer, Florencia Gorjón","doi":"10.5546/aap.2025-10816.eng","DOIUrl":"10.5546/aap.2025-10816.eng","url":null,"abstract":"<p><p>Anti-glomerular basement membrane disease is a rare pediatric autoimmune disease characterized by anti-glomerular basement membrane antibodies that cause rapidly progressive glomerulonephritis and alveolar hemorrhage. Central nervous system (CNS) involvement is sporadic. We present the case of a 13-year-old female patient with cerebral hemorrhage, septic shock, and multiorgan involvement, in whom the diagnosis of anti-glomerular basement membrane disease and CNS vasculitis in the absence of antineutrophil cytoplasmic antibodies (ANCA-negative) was confirmed. Combined treatment with glucocorticoids, cyclophosphamide, and plasmapheresis was performed, resulting in complete neurological and renal recovery. The rare coexistence of these two entities is analyzed. The case highlights the importance of maintaining a high index of diagnostic suspicion in the face of atypical clinical presentations.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202510816"},"PeriodicalIF":0.5,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145958631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rethinking perinatology. 反思围产期学。
IF 0.5 4区 医学
Archivos argentinos de pediatria Pub Date : 2026-07-31 Epub Date: 2026-03-05 DOI: 10.5546/aap.2026-11015.eng
Norma E Rossato
{"title":"Rethinking perinatology.","authors":"Norma E Rossato","doi":"10.5546/aap.2026-11015.eng","DOIUrl":"10.5546/aap.2026-11015.eng","url":null,"abstract":"","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202611015"},"PeriodicalIF":0.5,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147343438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dengue in children and adolescents with onco-hematological disease: a case series. 患有血液肿瘤的儿童和青少年的登革热：一个病例系列。
IF 0.5 4区 医学
Archivos argentinos de pediatria Pub Date : 2026-07-31 Epub Date: 2026-01-22 DOI: 10.5546/aap.2025-10815.eng
María A Rodríguez, María B Leone, Micaela Muras, María S Sznitowski, Marta Lavergne, Eliana Laurino
{"title":"Dengue in children and adolescents with onco-hematological disease: a case series.","authors":"María A Rodríguez, María B Leone, Micaela Muras, María S Sznitowski, Marta Lavergne, Eliana Laurino","doi":"10.5546/aap.2025-10815.eng","DOIUrl":"10.5546/aap.2025-10815.eng","url":null,"abstract":"<p><p>Dengue is a viral disease transmitted mainly by the Aedes aegypti mosquito. Argentina has seen a significant increase in epidemics in recent years. Pediatric patients with oncohematological diseases are particularly vulnerable due to their immunosuppression, which can predispose them to severe cases. This report presents five clinical cases of pediatric patients with oncohematological diseases who developed dengue infection, illustrating the variability in its clinical presentation. Symptoms were heterogeneous, ranging from mild forms to severe cases with liver failure, bleeding, and the need for intensive care. Early identification, close monitoring, and an interdisciplinary approach are key to management. This series of cases reinforces the need for active clinical surveillance for fever in an epidemiological context, even in the absence of typical symptoms.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202510815"},"PeriodicalIF":0.5,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146008574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Picky eating: Narrative review of a common challenge in pediatrics. 挑食：儿科常见挑战的叙述性回顾。
IF 0.5 4区 医学
Archivos argentinos de pediatria Pub Date : 2026-07-31 Epub Date: 2026-04-02 DOI: 10.5546/aap.2025-10941.eng
Carola Saure, Mabel Carosella, Luciana N Zonis
{"title":"Picky eating: Narrative review of a common challenge in pediatrics.","authors":"Carola Saure, Mabel Carosella, Luciana N Zonis","doi":"10.5546/aap.2025-10941.eng","DOIUrl":"10.5546/aap.2025-10941.eng","url":null,"abstract":"<p><p>Among the eating difficulties that can arise during childhood, picky eating has gained prominence in scientific literature due to its high prevalence and potential repercussions on nutritional status, psychosocial development, and family dynamics. It has been observed that picky eaters consume less of certain food groups and may have a lower intake of some macro- and micronutrients. Given the relevance of the topic, this narrative review aims to address the definition of picky eating in pediatrics, assessment criteria, risk factors, nutritional and psychosocial impacts, and the main evidence-based intervention strategies. An early, comprehensive, and interdisciplinary approach centered on the family is essential for managing picky eating, promoting healthy eating habits, and preventing nutritional and psychosocial consequences.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202510941"},"PeriodicalIF":0.5,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147580354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Incidence and epidemiology of pediatric acute respiratory distress syndrome in Argentina: Secondary analysis of data from the International PARDIE Study. 阿根廷儿童急性呼吸窘迫综合征的发病率和流行病学：国际PARDIE研究数据的二次分析
IF 0.5 4区 医学
Archivos argentinos de pediatria Pub Date : 2026-07-30 DOI: 10.5546/aap.2025-10987.eng
Matías G Herrera, Luis H Llano López, Analía Fernández, Ezequiel Monteverde, Silvio F Torres, Anoopindar Bhalla, Robinder G Khemani
{"title":"Incidence and epidemiology of pediatric acute respiratory distress syndrome in Argentina: Secondary analysis of data from the International PARDIE Study.","authors":"Matías G Herrera, Luis H Llano López, Analía Fernández, Ezequiel Monteverde, Silvio F Torres, Anoopindar Bhalla, Robinder G Khemani","doi":"10.5546/aap.2025-10987.eng","DOIUrl":"https://doi.org/10.5546/aap.2025-10987.eng","url":null,"abstract":"<p><p>Introduction. Pediatric acute respiratory distress syndrome (PARDS) poses a clinical challenge due to its highmorbidityandmortality.Specific diagnostic criteriaexistforthepediatricpopulation;however,evidence in our setting is limited. The objective of this study was to describe the incidence and characteristics of patients with PARDS admitted to Argentine pediatric intensive care units (PICUs) included in the PARDIE multicenter observational study, and to evaluate the factors associated with clinical outcomes. Population and methods. Secondary analysis of patients enrolled in Argentine pediatric intensive care units for the PARDIE study. Results. The incidence of PARDS in Argentina was 3.3% (61/1831) among patients admitted to the pediatric intensive care unit (PICU) and 5.1% (61/1203) among those who required mechanical ventilation. Of the 61 patients identified with PARDS, 43 had complete data for the outcome analysis. Mortality in this subgroup was 32.6% (14/43), significantly higher than in the other participating countries (16.1% [107/665]; p <0.01). Argentine patients presented with greater severity at admission, as evidenced by higher PIM3 and vasoactive-inotropic score (VIS) (p < 0.01). At the time of diagnosis of PARDS patients had higher values for tidal volume, peak inspiratory pressure, and FiO2 (p <0.01). In the exploratory multivariate analysis, mortality was associated with admission to Argentine PICUs and higher severity of PARDS, PIM3, VIS, and immunosuppression. Conclusion. The incidence of PARDS was higher than in previous epidemiological studies. The higher mortality rate in Argentine PICUs could be related to multiple factors, including severity at admission and a higher incidence of immunosuppression.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202510987"},"PeriodicalIF":0.5,"publicationDate":"2026-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148597931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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