Esther Rodríguez-Jiménez, Javier Martín-Ávila, Selene Valero-Moreno, José-Antonio Gil-Gómez, Inmaculada Montoya-Castilla, Marián Pérez-Marín
{"title":"Promoting health among adolescents with and without chronic illness through a serious game (emoTIChealth): An intervention and evaluation protocol.","authors":"Esther Rodríguez-Jiménez, Javier Martín-Ávila, Selene Valero-Moreno, José-Antonio Gil-Gómez, Inmaculada Montoya-Castilla, Marián Pérez-Marín","doi":"10.5546/aap.2025-11000.eng","DOIUrl":"10.5546/aap.2025-11000.eng","url":null,"abstract":"<p><p>Introduction. Adolescence is a stage characterized by significant emotional, cognitive, and social changes. The presence of chronic physical illness during this period can increase the risk of psychological distress and negatively affect quality of life and the adoption of healthy habits. In this context, digital interventions based on serious games represent an innovative strategy for promoting health among adolescents. Objective: To describe the design and implementation protocol for emoTIChealth, a psychoeducational serious game aimed at adolescents aged 12-16, with and without chronic physical illnesses, designed to promote physical and emotional health, social-emotional skills, and healthy habits.Population and methods. A quasi-experimental, longitudinal, within-subject design with repeated measures at three time points. The intervention is structured around six areas: emotional awareness and regulation, cognitive coping, identity, social relationships and communication, and physical wellbeing. Psychological variables (such as health-related quality of life, self-concept, and resilience) will be assessed using validated instruments. Following the completion of emoTIChealth, we plan to evaluate pre- and post-intervention changes in indicators of health-related quality of life, socio-emotional skills, self-concept, resilience, and healthy habits, as well as a reduction in psychological symptoms. Conclusion. EmoTIChealth is an innovative digital intervention designed for educational and healthcare settings that holistically promotes adolescent health, regardless of whether the adolescent has a chronic illness or not, and its impact will be evaluated in a longitudinal quasi-experimental study currently in the implementation phase.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202511000"},"PeriodicalIF":0.5,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147925935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fewer births, new challenges: The impact of the global decline in fertility on pediatrics.","authors":"Fernando Ferrero","doi":"10.5546/aap.2026-11079.eng","DOIUrl":"10.5546/aap.2026-11079.eng","url":null,"abstract":"","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202611079"},"PeriodicalIF":0.5,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147670033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Acute heart failure in an infant with methylmalonic acidemia: a diagnostic and therapeutic challenge.","authors":"José M Vera García, Nicolás Guerrero, Sofía Paz","doi":"10.5546/aap.2025-10919.eng","DOIUrl":"10.5546/aap.2025-10919.eng","url":null,"abstract":"<p><p>Methylmalonic acidemia is characterized by the inability to convert L-methylmalonyl-CoA to succinylCoA, resulting in the accumulation of methylmalonic acid in the blood and/or urine. In its chronic form, it can cause cardiomyopathy with impaired cardiac function. Its management is based on several pillars; the most important is intramuscular hydroxycobalamin supplementation, which serves as a cofactor for methylmalonyl-CoA mutase. We present the case of a 6-month-old girl who was admitted to the emergency department with signs of heart failure. A multidisciplinary evaluation was performed to determine the etiology, and methylmalonic acidemia was diagnosed. We also report a novel route of administration for hydroxycobalamin in this condition (subcutaneous). We present the diagnostic approach and therapeutic challenges in this patient, given that the usual route of administration of hydroxycobalamin was contraindicated due to her comorbidities.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202510919"},"PeriodicalIF":0.5,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146193929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrés Caretta, Agustín Cavagna, Andrea Muñoz, Facundo Jorro Barón
{"title":"Implementation of the Pediatric Early Warning Score for the early identification of clinical deterioration in an Argentine hospital.","authors":"Andrés Caretta, Agustín Cavagna, Andrea Muñoz, Facundo Jorro Barón","doi":"10.5546/aap.2025-10993.eng","DOIUrl":"10.5546/aap.2025-10993.eng","url":null,"abstract":"<p><p>Introduction. Unexpected clinical deterioration in hospitalized pediatric patients can precede serious events and unscheduled transfers to the pediatric intensive care unit (PICU). Early warning scales, such as the Pediatric Early Warning Score (PEWS), aim to facilitate its early detection. The objective was to implement PEWS use in at least 50% of hospitalized patients and to describe clinical variables associated with unscheduled transfers. Population and methods. A quasi-experimental before-and-after study was conducted at a pediatric hospital between April 2024 and January 2025. A SAFE (Situational Awareness for Everyone) situational awareness protocol was implemented, along with the use of the PEWS, staff training, briefings, and debriefing sessions. The study included patients aged 1 month to 18 years who were admitted to the PICU unscheduled. Adherence to PEWS documentation and associated clinical variables were evaluated. Results. A total of 104 unscheduled transfers were recorded (46 pre-intervention, 58 post-intervention). The groups were comparable in terms of age, comorbidities, days before transfer, length of stay in the PICU, and PIM3. Adherence to the PEWS was 58.6% in the post-intervention phase, increasing to 100% by the end of the period. The median PEWS score for unscheduled transfers was 6 (IQR 3-7). No differences were observed in the need for intervention within the first hour in the PICU or in mortality. Conclusion. The implementation of the PEWS was feasible and exceeded the proposed target. It had no clinical impact at this stage, but the high adherence achieved is key for future evaluations of effectiveness and sustainability.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202510993"},"PeriodicalIF":0.5,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147760735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pablo E Petracca, Alejandro Siaba Serrate, Mónica A R Centeno, Deborah Turina, Daniela Morell, Flavio Requejo, Diego Brandoni, Paula Caporal, Agustina Mayans, Gustavo Costales, Thomas Iolster
{"title":"Stroke in children: Consensus on diagnosis and treatment.","authors":"Pablo E Petracca, Alejandro Siaba Serrate, Mónica A R Centeno, Deborah Turina, Daniela Morell, Flavio Requejo, Diego Brandoni, Paula Caporal, Agustina Mayans, Gustavo Costales, Thomas Iolster","doi":"10.5546/aap.2025-10660","DOIUrl":"10.5546/aap.2025-10660","url":null,"abstract":"<p><p>Pediatric stroke (PS) may be ischemic or hemorrhagic and affects patients from birth to 18 years. Although its incidence is low, it carries significant morbidity and mortality. Diagnosis is frequently delayed due to low clinical suspicion and age-dependent symptoms, making early recognition essential for better outcomes. Neuroimaging, particularly magnetic resonance imaging (MRI) and computed tomography (CT), is fundamental for confirmation. For ischemic PS, reperfusion therapies such as thrombolysis and mechanical thrombectomy are treatment options in selected cases. Hospital mortality ranges from 3 % to 6 % for ischemic stroke and is higher for hemorrhagic forms. Long-term complications include epilepsy and persistent neurological deficits. Improving care requires educational tools and multidisciplinary training for prehospital and hospital teams, along with institution-specific protocols. Implementing these measures does not demand additional resources but rather adaptation and professional education to ensure timely diagnosis and treatment.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202510660"},"PeriodicalIF":0.5,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147760686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Natalia L Pugliese, Patricia I Tabacco, María Del C Campos
{"title":"Feeding disorders in children with congenital heart disease: clinical implications and the role of the speech and language pathologist.","authors":"Natalia L Pugliese, Patricia I Tabacco, María Del C Campos","doi":"10.5546/aap.2025-10805.eng","DOIUrl":"10.5546/aap.2025-10805.eng","url":null,"abstract":"<p><p>Medical and technological advances have increased the survival rate of children with congenital heart disease, which has led to a deeper understanding of various aspects of their subsequent development. Cardiovascular involvement has a direct impact on feeding, causing sucking and swallowing dysfunctions from birth that can trigger a series of consequences such as malnutrition, dysphagia, and clinical discomfort. This problem not only affects the physiological sphere but also the emotional and family dimensions. This article summarizes key findings in the growing literature on the impact of heart disease on pediatric nutrition and emphasizes the role of speech-language pathology. Further research on this issue is needed to provide greater knowledge that improves the quality of life of these children and their families.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202510805"},"PeriodicalIF":0.5,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146008545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vanesa E Castellano, Mariela Del Pino, Sofía Diana Menéndez, Fernando Fernández, Pablo Bonvehí, Andreina Verdi, Nadia Sosa, Jésica Vera, Mirtha Valdeolmillos, Romina Gigliotti, Mariano Díaz, Fernando Burgos
{"title":"First year of nirsevimab use in Argentina (2025): Report from a private vaccination center.","authors":"Vanesa E Castellano, Mariela Del Pino, Sofía Diana Menéndez, Fernando Fernández, Pablo Bonvehí, Andreina Verdi, Nadia Sosa, Jésica Vera, Mirtha Valdeolmillos, Romina Gigliotti, Mariano Díaz, Fernando Burgos","doi":"10.5546/aap.2026-11018.eng","DOIUrl":"10.5546/aap.2026-11018.eng","url":null,"abstract":"<p><p>Introduction. Since March 2025, nirsevimab, a monoclonal antibody for the prevention of respiratory syncytial virus infection (RSV), has been available in Argentina. The objective of this study was to describe the use of nirsevimab at a private vaccination center in the Buenos Aires Metropolitan Area, including the profile of infants vaccinated during its first year on the market. Population and methods. A descriptive study was conducted using an online survey administered to caregivers of children who received nirsevimab. The study analyzed sociodemographic variables, medical history, maternal RSV vaccination status, and the reason for the recommendation. Results. A total of 232 caregivers responded; 93.5% were mothers, with a mean age of 37.1 years (SD 5.4); 92.7% had a college or university education; 99.6% had health insurance. The mean age of the immunized children was 6.0 months (SD 3.9; range 0-21); 53.9% were male (N=125); 19.8% attended daycare (N = 46); 10.8% (N = 25) had comorbidities, primarily heart disease (5.6%; N = 13) and chronic respiratory disease (4.7%; N = 11); 19.0% (N = 44) had ≥1 episode of bronchiolitis. Reasons for recommendation: unvaccinated mother: 51.3% (N = 119); maternal vaccination in the previous year: 18.5% (N = 43); preterm infants <34 weeks: 14.7% (N = 34); risk factors: 6.5% (N = 15). The recommendation came from the pediatrician in 81.5% of cases (N = 189). Conclusion. More than half of the administered doses were applied to infants who lacked protection from maternal immunity. Most were healthy infants during their first season and were recommended for immunization by their pediatrician.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202611018"},"PeriodicalIF":0.5,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148026033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pablo N Affranchino, Mariana Roizen, Silvia Caino, Natalia Torres Huamani, Darío Teplisky
{"title":"Quality of life in children with complex vascular anomalies treated with sirolimus: A quasi-experimental study.","authors":"Pablo N Affranchino, Mariana Roizen, Silvia Caino, Natalia Torres Huamani, Darío Teplisky","doi":"10.5546/aap.2025-10712.eng","DOIUrl":"10.5546/aap.2025-10712.eng","url":null,"abstract":"<p><p>Introduction. Complex vascular anomalies have a severe impact on quality of life. Sirolimus is used offlabel, but local evidence regarding its impact on health-related quality of life (HRQoL) is limited. Objective. To evaluate the effect of sirolimus treatment in patients with complex vascular anomalies. Population and methods. A single-group, quasi-experimental before-and-after study without a control group, conducted at a pediatric hospital. Patients aged 4 to 21 years with complex vascular malformations were included. HRQoL was measured using the PedsQL 4.0 questionnaire before starting sirolimus and at 6 months. Clinical characteristics, pain intensity and duration, and adverse events were recorded, and multivariate analyses were performed. Results. A total of 39 patients were included (56.4% were female). At baseline, low HRQoL scores were observed. After 6 months of treatment, total scores increased from 64.6 (29.34-94.5) to 79.9 (55.43-98.91) in self-reports and from 65.2 (27.17-90.62) to 77.2 (46.73-93.47) in caregiver reports (p <0.005). Chronic pain, present in 21 patients (53.8%), was the main factor associated with a worse baseline HRQoL (-14.4 points; 95% CI -24.4 to -4.3; p = 0.0065) and decreased in 95% of patients. Adverse events, observed in 41%, were mild and did not require treatment discontinuation. Conclusion. Treatment with sirolimus was associated with an improvement in HRQoL and pain in pediatric patients with complex vascular anomalies.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202510712"},"PeriodicalIF":0.5,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147760692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
José M Vera García, Julieta Pontoriero Daroni, María C Malzone
{"title":"Cross-cultural adaptation of the Paediatric Palliative Screening Scale for the early referral of pediatric patients to palliative care teams.","authors":"José M Vera García, Julieta Pontoriero Daroni, María C Malzone","doi":"10.5546/aap.2025-10927.eng","DOIUrl":"10.5546/aap.2025-10927.eng","url":null,"abstract":"<p><p>Introduction. The Paediatric Palliative Screening Scale (PaPaS Scale) is a tool designed to help identify children aged 1 to 18 who would benefit from pediatric palliative care (PPC) and to facilitate early referral. No similar tool exists in Spanish. The objective was to translate and cross-culturally adapt the PaPaS Scale into Spanish for screening and early referral to PPC teams for pediatric patients aged 12 months to 18 years with life-threatening or life-limiting illnesses. Methods. Translation and cultural adaptation of the PaPaS Scale into Spanish, consisting of five phases: obtaining authorization from the scale's authors, direct translation, back-translation, evaluation by a committee of experts, and pretesting. Results. Authorization was obtained from the scale's author, Eva Bergstraesser; this was followed by a direct translation (with subsequent reconciliation), a back-translation of the resulting scale into English, validation by a committee of experts in research, health sciences, and humanities; and a pretest consisting of an evaluation of the scale by five physicians specializing in PPC. At each stage, the necessary changes were made to adapt the scale. Conclusion. A culturally adapted Spanish-language scale was developed that could serve as a useful tool for the early identification of PPC in pediatric care, following appropriate validation.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202510927"},"PeriodicalIF":0.5,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147970031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The current dengue vaccine landscape, with a focus on TAK-003 (Qdenga®).","authors":"Gustavo H Marín, Anahí Álvarez Rotondo","doi":"10.5546/aap.2025-10990.eng","DOIUrl":"10.5546/aap.2025-10990.eng","url":null,"abstract":"","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202510990"},"PeriodicalIF":0.5,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146050078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}