Stefano Cacciatore , Emanuele Marzetti , Riccardo Calvani , Matteo Tosato , Francesco Landi , Lookup 8+ Study Group
{"title":"Association between cardiovascular health metrics and self-reported walking difficulty in community-dwelling middle-aged and older adults: results from the longevity check-up (Lookup) 8+","authors":"Stefano Cacciatore , Emanuele Marzetti , Riccardo Calvani , Matteo Tosato , Francesco Landi , Lookup 8+ Study Group","doi":"10.1016/j.archger.2025.106027","DOIUrl":"10.1016/j.archger.2025.106027","url":null,"abstract":"<div><h3>Objectives</h3><div>To examine the association between cardiovascular health, assessed through an 8-factor cardiovascular health (8F–CVH) score, and self-reported walking difficulty in middle-aged (40–64 years) and older adults (≥65 years) living in the community.</div></div><div><h3>Study design</h3><div>Cross-sectional study.</div></div><div><h3>Main outcome measures</h3><div>Self-reported walking difficulty was evaluated by a single-item question: “Do you have any difficulty in walking 400 meters?”. Cardiovascular health was assessed using a composite 8F–CVH score inspired by Life’s Essential 8, including diet, physical activity, body mass index, blood pressure, total cholesterol, fasting blood glucose, smoking status, and sleep quality.</div></div><div><h3>Results</h3><div>Among 4141 participants (mean age 60.5 ± 11.2 years; 53.1 % women), 16.0 % reported walking difficulty. Prevalence was higher in older adults (25.0 %) than in middle-aged individuals (11.0 %; p for trend <0.001). Self-reported walking difficulty was more frequent in participants with low 8F–CVH scores (32.8 %), compared to moderate (15.5 %) and high (4.8 %) scores (p <0.001). ROC curve analysis showed modest discrimination for the total score (area under the curve [AUC] 0.67; 95 % confidence interval [CI] 0.65–0.69), with physical activity performing best among individual components (AUC 0.69; 95 % CI 0.67–0.71). After adjusting for confounders, moderate and high scores were associated with 61 % (OR 0.39, 95 % CI 0.31–0.48) and 84 % (OR 0.16, 95 % CI 0.10–0.24) lower odds of self-reported walking difficulty, respectively.</div></div><div><h3>Conclusions</h3><div>Better cardiovascular health is independently associated with lower odds of self-reported walking difficulty. Promoting cardiovascular health may help preserve mobility in late life.</div></div>","PeriodicalId":8306,"journal":{"name":"Archives of gerontology and geriatrics","volume":"139 ","pages":"Article 106027"},"PeriodicalIF":3.8,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145095504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Normative reference values for the six-minute walk test in older adults: A systematic review and meta-analysis","authors":"Khadijeh Otadi, Kazem Malmir","doi":"10.1016/j.archger.2025.106026","DOIUrl":"10.1016/j.archger.2025.106026","url":null,"abstract":"<div><h3>Background</h3><div>The six-minute walk test (6MWT) is widely used to assess functional capacity in older adults, but performance differs by various factors. This review compiled 6MWT reference values and identified key predictors of performance.</div></div><div><h3>Methods</h3><div>Studies on average 6MWT distances in older adults were found through PubMed, Scopus, Web of Science, Ovid, and PEDro, with no date limits. Participant data were summarized using descriptive statistics. A random-effects meta-analysis combined mean distances, with heterogeneity assessed using Cochran's Q test and I² statistics. Subgroup analyses examined variations by age, gender, BMI, height, and region, while regression analyses identified predictors of 6MWT performance.</div></div><div><h3>Results</h3><div>Of 72 studies, 28 were included in the meta-analysis. Men walked farther (473.11 m) than women (428.35 m). Distance declined with age, from 587.43 m (age 60–64) to 325.53 m (age ≥80). Overweight participants walked more (461.24 m) than those with normal BMI (425.33 m). By region, Oceania showed the highest distance (485.42 m), followed by Europe, the Americas, and Asia. Meta-regression showed distance decreased by 10.25 m per year of age and increased by 4.44 m per kg of weight. Gender, BMI, and height were not significant predictors.</div></div><div><h3>Conclusions</h3><div>The 6MWT remains a valuable tool for assessing functional capacity in older adults. Age and weight were the most significant predictors of 6MWT performance, with distance decreasing markedly with age and increasing with body weight. Regional factors also influenced outcomes, while gender, BMI, and body height had less impact. Clinicians should use age-adjusted evaluations and promote weight management strategies to preserve mobility in older adults.</div></div>","PeriodicalId":8306,"journal":{"name":"Archives of gerontology and geriatrics","volume":"140 ","pages":"Article 106026"},"PeriodicalIF":3.8,"publicationDate":"2025-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145202311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gee Youn Song , Sung-Bum Lee , Minkyeung Jo , Ji-Eun Moon , Inki Moon , Jong-Koo Kim
{"title":"Handgrip strength as a predictor of new-onset cardiovascular disease: insights from the Korean genome and epidemiology study (KoGES) cohort","authors":"Gee Youn Song , Sung-Bum Lee , Minkyeung Jo , Ji-Eun Moon , Inki Moon , Jong-Koo Kim","doi":"10.1016/j.archger.2025.106023","DOIUrl":"10.1016/j.archger.2025.106023","url":null,"abstract":"<div><h3>Background and aims</h3><div>Handgrip strength (HGS) has been identified as a predictor of various comorbidities, including pneumonia, chronic kidney disease, and cancer. Additionally, HGS has been associated with the prevalence of cardiovascular disease (CVD). However, the usefulness of HGS as an indicator of incident CVD remains unclear.</div></div><div><h3>Methods</h3><div>In this nationwide cohort study, 173,195 subjects were enrolled and followed for 4.1 years. A total of 35,664 participants were included in the final analysis. During the follow-up, 131 participants developed cerebrovascular disease, 401 experienced coronary heart disease (CHD), and 526 developed CVD. Anthropometric, laboratory, and lifestyle factors were assessed in relation to CVD risk.</div></div><div><h3>Results</h3><div>Participantswere categorised into quartiles based on their relative handgrip strength (RGS). Cox regression analyses revealed an inverse association between RGS and new-onset cerebrovascular disease, CHD, and CVD. After controlling for confounders, the hazard ratios (HRs) [95 % confidence intervals (CIs)] for new-onset CHD were 0.63 (0.41–0.98) in men and 0.50 (0.26–0.95) in women. Additionally, after adjusting for confounders, the HRs [95 % CIs] for incident CVD in the highest quartile (Q4)were 0.68 (0.47–1.00) in men and 0.50 (0.28–0.89) in women. As RGS increased, the incidence of CHD and CVD significantly decreased, with stronger associations observed in women.</div></div><div><h3>Discussion and Conclusions</h3><div>This novel study demonstrates an association between RGS and incident CHD and CVD, with stronger significance in women. In clinical settings, RGS can be a useful surrogate markerof CHD and CVD, and regular assessments may help detect these conditions early.</div></div>","PeriodicalId":8306,"journal":{"name":"Archives of gerontology and geriatrics","volume":"139 ","pages":"Article 106023"},"PeriodicalIF":3.8,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145095505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effectiveness of web-based interventions on depression and anxiety in older adults: a systematic review and meta-analysis of randomized controlled trials","authors":"Lorinda A. Coombs , Myoungsuk Kim","doi":"10.1016/j.archger.2025.106025","DOIUrl":"10.1016/j.archger.2025.106025","url":null,"abstract":"<div><h3>Objective</h3><div>This study examined the effects of web-based interventions on depression and anxiety in older adults.</div></div><div><h3>Methods</h3><div>We conducted a systematic search of PubMed, CINAHL, Cochrane, Embase, PsycINFO, and Web of Science from their inception to March 05, 2025. We included randomized controlled trials (RCTs) examining the effects of web-based interventions on depression and anxiety in individuals aged 60 and older. The quality of included studies was evaluated using the revised Cochrane risk-of-bias tool for RCTs. A random-effects model was applied for the meta-analysis, with pooled standardized mean differences (SMD) used to estimate intervention effects. Heterogeneity was quantified using the I² statistic, and subgroup and meta-regression analyses were performed to investigate potential moderators.</div></div><div><h3>Results</h3><div>A total of 19 studies were included in the final analysis. The meta-analysis showed that web-based interventions significantly reduced depression (SMD = -0.48, 95 % CI = -0.72 to -0.24) and anxiety (SMD = -0.70, 95 % CI = -0.97 to -0.43) in older adults. Subgroup analyses indicated that participant characteristics and publication year significantly moderated heterogeneity, while meta-regression analysis revealed that mean age significantly moderated the intervention effect.</div></div><div><h3>Conclusion</h3><div>This meta-analysis confirmed that web-based interventions effectively reduce depression and anxiety in older adults. The effects were particularly pronounced among older adults with existing or diagnosed symptoms of depression or anxiety. Furthermore, the observed reduction in intervention effectiveness after COVID-19 highlights the need to investigate the underlying causes of this decline.</div></div>","PeriodicalId":8306,"journal":{"name":"Archives of gerontology and geriatrics","volume":"139 ","pages":"Article 106025"},"PeriodicalIF":3.8,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145082649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xiaowei Li , Chenxi Wu , Tao Feng , Xinyu Chen , Huan Chen , Xianying Lu , Jing Gao , Chaoming Hou
{"title":"Loneliness trajectories in older adults: A systematic review","authors":"Xiaowei Li , Chenxi Wu , Tao Feng , Xinyu Chen , Huan Chen , Xianying Lu , Jing Gao , Chaoming Hou","doi":"10.1016/j.archger.2025.106024","DOIUrl":"10.1016/j.archger.2025.106024","url":null,"abstract":"<div><h3>Background</h3><div>Loneliness in older adults is a critical public health issue with dynamic changes over time. Understanding its longitudinal patterns is vital for identifying high-risk individuals and developing timely interventions. This review synthesizes evidence on loneliness trajectories, their predictors, and associated health outcomes in older populations.</div></div><div><h3>Methods</h3><div>A systematic search across nine databases (PubMed, Web of Science, Embase, Cochrane Library, CINAHL, PsycINFO, CNKI, VIP, Wanfang) was conducted from inception to December 1, 2024, updated on August 18, 2025, focusing on longitudinal studies of adults aged ≥60 years. Quality was assessed using JBI tools, and a narrative synthesis was performed due to methodological heterogeneity.</div></div><div><h3>Results</h3><div>Of the 2985 screened records, 16 studies met the predefined inclusion criteria. Fifteen of these studies were rated as moderate or high quality. Despite heterogeneity in analytical approaches, four loneliness trajectory patterns were identified: stable-low, stable-high, ascending, and descending. The stable-high and ascending trajectories were consistently associated with adverse health outcomes, including accelerated cognitive decline and greater severity of depressive symptoms. Key predictors of high-risk loneliness trajectories included social isolation, functional impairment, and exposure to major life stressors.</div></div><div><h3>Conclusions</h3><div>Loneliness among older adults follows heterogeneous trajectories, with the stable-high and ascending patterns indicating the highest risk for adverse health outcomes. These findings underscore the need for early screening of key risk factors and the implementation of trajectory-tailored interventions. Future research should prioritize standardized loneliness measurement tools and integrated analytical approaches to enhance the comparability of findings and their translation into clinical practice.</div></div>","PeriodicalId":8306,"journal":{"name":"Archives of gerontology and geriatrics","volume":"139 ","pages":"Article 106024"},"PeriodicalIF":3.8,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145087951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Thomas Iverson , Marie Schulze , Kaylen Gill , Yola Switkowski , Isis Kelly dos Santos , Maureen C. Ashe
{"title":"Older adults and social support in rural Canada: A rapid mixed methods systematic review to inform social prescribing","authors":"Thomas Iverson , Marie Schulze , Kaylen Gill , Yola Switkowski , Isis Kelly dos Santos , Maureen C. Ashe","doi":"10.1016/j.archger.2025.106022","DOIUrl":"10.1016/j.archger.2025.106022","url":null,"abstract":"<div><h3>Objectives</h3><div>Social support may assist people’s health as they age but less is known about how this relationship may differ for older adults living in rural communities. Knowledge of this information can inform the implementation of social prescribing, a care model aiming to address people’s unmet non-medical social needs.</div></div><div><h3>Methods</h3><div>This was a systematic rapid mixed-methods review following guidelines. We searched 10 electronic sources (all languages from 2000 and later) for peer-reviewed studies; our last search was on May 5, 2025. We followed the Joanna Briggs Institute (JBI) mixed-methods approach and used a convergent integrated method to create qualitative findings from quantitative studies and merged them with data from qualitative studies.</div></div><div><h3>Synthesis</h3><div>We included 12 studies (14 publications) with six quantitative studies, five qualitative studies, and one mixed methods study. Data were from Canada-wide surveys, or the provinces of New Brunswick, Ontario, Quebec, and Saskatchewan. There were some differences in findings between older adults from rural and urban settings for social support and satisfaction. Older people in rural settings may have less access to “formal” support and may rely more on family or friends, but this “patchwork” of support in rural communities may be less sustainable.</div></div><div><h3>Conclusion</h3><div>Social support is an important part of aging, but there may be some unique differences for people living in rural Canadian communities. Although the support provided in rural settings may offer some advantages, it may also be precarious in the long term and innovations to support aging in place (like social prescribing) are long overdue.</div></div><div><h3>Systematic Review Registration</h3><div>PROSPERO 2024 CRD42024591884</div></div>","PeriodicalId":8306,"journal":{"name":"Archives of gerontology and geriatrics","volume":"139 ","pages":"Article 106022"},"PeriodicalIF":3.8,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145095509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xuan Huang , Cui Ye , Ai Zhao , Ziyu Wang , Shufang Zuo , Lu Lin
{"title":"Effects of reminiscence therapy on cognitive function in older adults with cognitive impairment: a systematic review and meta-analysis of randomized controlled trials","authors":"Xuan Huang , Cui Ye , Ai Zhao , Ziyu Wang , Shufang Zuo , Lu Lin","doi":"10.1016/j.archger.2025.106021","DOIUrl":"10.1016/j.archger.2025.106021","url":null,"abstract":"<div><h3>Objectives</h3><div>To evaluate the effectiveness of reminiscence therapy in enhancing cognitive function among older adults with cognitive impairment and to identify optimal intervention strategies in terms of format, session duration, frequency, and intervention period.</div></div><div><h3>Methods</h3><div>A systematic search of randomized controlled trials (RCTs) on reminiscence therapy for cognitively impaired older adults was conducted across PubMed, Web of Science, Cochrane Library, Embase, CNKI, CBM, VIP, and Wanfang databases from inception to October 2024. Two reviewers independently assessed the methodological quality of included studies using Cochrane Risk of Bias Tool (ROB 2.0). Data were extracted using standardized forms and analyzed with Review Manager version 5.4 and Stata version 18.0.</div></div><div><h3>Results</h3><div>A total of 18 studies were included, of which 14 studies (19 trials) provided complete data for meta-analysis. Study settings included hospitals, nursing facilities, and community centers, with all interventions based on simple recall reminiscence. Meta-analysis showed a significant effect of reminiscence therapy on cognitive function in older adults with cognitive impairment (SMD=1.15, 95%CI: 0.78-1.52, P<0.001). Subgroup analyses revealed greater effectiveness in participants from Asia (SMD=1.50, 95%CI: 0.98-2.01, P<0.001) and those with mild cognitive impairment (MCI)(SMD=1.56, 95%CI: 0.78-2.34, P<0.001). The optimal delivery strategies involved group sessions with more than six participants (SMD=1.63, 95%CI: 0.48-2.78, P=0.005), conducted weekly (SMD=1.37, 95%CI: 0.83-1.91, P<0.001) for 30-45 minutes per session (SMD=1.29, 95%CI: 0.59-1.99, P<0.001), over a 12-week period (SMD=1.60, 95%CI: 0.83-2.38, P<0.001).</div></div><div><h3>Conclusion</h3><div>Reminiscence therapy effectively improves cognitive function in older adults with cognitive impairment, especially those with MCI. It is recommended as an early non-pharmacological intervention delivered through weekly group sessions of 30-45 minutes, with six or more participants over at least 12 weeks. Future research should involve high-quality studies with extended follow-up periods to fully validate the sustained effectiveness of reminiscence therapy.</div></div>","PeriodicalId":8306,"journal":{"name":"Archives of gerontology and geriatrics","volume":"139 ","pages":"Article 106021"},"PeriodicalIF":3.8,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145060388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hang Yuan , Yizhong Bao , Li Li , Yepeng Luan , Fangcai Li
{"title":"A novel HDAC1-specific inhibitor prevents estrogen deficiency-induced osteoporosis in mice by inhibiting osteoclast function","authors":"Hang Yuan , Yizhong Bao , Li Li , Yepeng Luan , Fangcai Li","doi":"10.1016/j.archger.2025.106020","DOIUrl":"10.1016/j.archger.2025.106020","url":null,"abstract":"<div><div>Postmenopausal osteoporosis (PMOP) features reduced bone mass and deteriorated bone microstructure, increasing fracture risk. Estrogen deficiency-induced osteoclast overactivation is a primary driver. OCP-001, a novel highly selective HDAC1 inhibitor, was investigated. TRAP staining showed dose-dependent inhibition of osteoclast differentiation by OCP-001. qPCR revealed concomitant downregulation of RANKL-induced osteoclast marker genes (<em>Trap, DC-Stamp, NFATc1, ATP60</em>) and key regulatory proteins (c-Fos, NFATc1, Blimp-1, IRF-8). In an ovariectomized (OVX)-induced PMOP mouse model, body weight monitoring showed no toxicity from OCP-001 treatment. Micro-CT analysis confirmed that it effectively prevented femoral bone mass loss and microstructural deterioration. Histological analysis further verified its inhibition of OVX-induced osteoclastogenesis. Furthermore, OCP-001 normalized OVX-altered serum bone turnover markers (PINP, β-CTx). Mechanistically, OCP-001 suppressed osteoclast differentiation partly via inhibiting the Blimp-1/IRF-8 pathway. Thus, the selective HDAC1 inhibitor OCP-001 alleviates OVX-induced bone loss and deterioration by potently inhibiting osteoclastogenesis and function, supporting its potential as a PMOP therapeutic.</div></div>","PeriodicalId":8306,"journal":{"name":"Archives of gerontology and geriatrics","volume":"139 ","pages":"Article 106020"},"PeriodicalIF":3.8,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144932596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Associations of frailty and its changes with the risks of depressive symptoms: A multi-cohort study","authors":"Zhuling Yu , Yanbo Teng , Le Peng","doi":"10.1016/j.archger.2025.106019","DOIUrl":"10.1016/j.archger.2025.106019","url":null,"abstract":"<div><h3>Background</h3><div>Frailty is a dynamic condition that may affect mental health. This study aimed to investigate the associations of frailty and its changes with the risks of depressive symptoms across multiple regions in aging populations.</div></div><div><h3>Methods</h3><div>Data were drawn from five cohort studies in the United States, England, Europe, China, and Mexico. Frailty was assessed by frailty index which included chronic diseases, vision and hearing impairments, pain, self-reported health status, activity of daily living, instrumental activity of daily living, mobility, and cognitive function. Changes in frailty were evaluated by frailty at baseline and the first follow-up survey. Unadjusted and adjusted hazard ratios (HRs) with 95% confidence intervals [CIs] were estimated by Cox proportional hazards models and then pooled by meta-analyses.</div></div><div><h3>Results</h3><div>Of the 61,063 participants, 17,960 developed depressive symptoms during a median time of 5.9 to 9.0 years. Baseline frailty was significantly associated with an increased risk of depressive symptoms. Participants who changed from robust to pre-frail or frail status showed an elevated risk of depressive symptoms compared to stable robust participants (HR range: 1.38–1.81; pooled HR: 1.53, 95% CI: 1.37–1.72). Conversely, participants who transitioned from frail to robust or pre-frail status demonstrated a reduced risk of depressive symptoms compared to stable frail participants (HR range: 0.36–0.78; pooled HR: 0.71, 95% CI: 0.63–0.79).</div></div><div><h3>Conclusion</h3><div>Baseline frailty was associated with incident depressive symptoms. Deterioration of frailty elevated the risk of depressive symptoms, whereas improvement of frailty lowered the risk. This study suggests that timely interventions for frailty may prevent depressive symptoms.</div></div>","PeriodicalId":8306,"journal":{"name":"Archives of gerontology and geriatrics","volume":"139 ","pages":"Article 106019"},"PeriodicalIF":3.8,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145019373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yaqi Huang , Youran Liu , Chun Man Wong , Yaqian Liu , Juan Chen , Angela Yee Man Leung
{"title":"Understanding barriers and facilitators to oral health interventions in community-dwelling older adults with cognitive impairment: A scoping review","authors":"Yaqi Huang , Youran Liu , Chun Man Wong , Yaqian Liu , Juan Chen , Angela Yee Man Leung","doi":"10.1016/j.archger.2025.106014","DOIUrl":"10.1016/j.archger.2025.106014","url":null,"abstract":"<div><h3>Background</h3><div>Older adults with cognitive impairment face significant challenges in maintaining oral health while the barriers and facilitators for implementing communitybased oral health interventions are uncertain.</div></div><div><h3>Objective</h3><div>To understand the barriers and facilitators for the implementation of oral health intervention among community-dwelling older adults with cognitive impairment.</div></div><div><h3>Methods</h3><div>Literature was searched in PubMed, CINAHL, Embase, PsycINFO, Scopus and Google Scholar. Studies reporting oral health interventions for community-dwelling older adults with cognitive impairment were included. Behaviour Change Techniques (BCTs) were identified and classified using BCT Taxonomy v1. Barriers and facilitators to the implementation were synthesized using thematic analysis.</div></div><div><h3>Results</h3><div>Eleven studies were included. Four types of interventions with 20 distinct BCTs were identified. Facilitators included: 1) Adaptive solutions improved usability and accessibility; 2) Training and guidance enhance the feasibility; 3) The involvement of professionals and care partners ensured the adoption of the new oral hygiene routines; and 4) Participants in earlier stages of cognitive impairment can gradually adjust to new oral care routines. Barriers included: 1) Technique challenges and physical limitations affected participants’ ability to perform correct oral hygiene tasks; 2) Memory decline, emotional distress, and lack of motivation hindered participants' engagement and adherence to oral health practices; 3) Care partners burdens and unmet needs affected consistent support; and 4) Logistical constraints and cultural factors influenced participation and access to oral health interventions.</div></div><div><h3>Conclusions</h3><div>While various interventions have been developed, evidence remains limited. Incorporating user-friendly hygiene techniques, more BCTs, appropriate technical support, caregiver involvement, and oral–cognitive dual-task training were recommended.</div></div>","PeriodicalId":8306,"journal":{"name":"Archives of gerontology and geriatrics","volume":"139 ","pages":"Article 106014"},"PeriodicalIF":3.8,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145004740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}