Archives of gerontology and geriatrics最新文献

{"title":"“Realising my full potential despite the deterioration”: Examining older adults’ experiences and perceptions of healthy ageing","authors":"Wei Qi Koh ,&nbsp;Jacki Liddle ,&nbsp;Nancy A Pachana ,&nbsp;Kristiana Ludlow","doi":"10.1016/j.archger.2025.105955","DOIUrl":"10.1016/j.archger.2025.105955","url":null,"abstract":"<div><h3>Introduction</h3><div>Fostering healthy ageing among older adults has been identified as a global priority by the World Health Organization and many countries. Individuals ascribe social meanings to the ageing process, and perceptions of ageing well can be influenced by cultural expectations and social contexts. Accordingly, it is necessary to explore how older adults perceive healthy ageing, how they experience and create meanings of the ageing process.</div></div><div><h3>Methods</h3><div>A descriptive qualitative study was conducted. Purposive sampling was used to recruit older adults who were aged 55 and above, living in the community, who spoke and understood English, and resided in Australia. Twenty participants were recruited for five focus groups that were conducted between April to June 2024. All focus groups were recorded and transcribed verbatim. Data were analysed using reflexive thematic analysis.</div></div><div><h3>Findings</h3><div>All participants resided in Brisbane, Australia. The mean age of participants was 75.4 years, and there was a similar proportion of male and female participants. Five themes were generated: 1) living to full potential, 2) diversity in activities, routines and preferences, 3) participation and preferences in activities and groups, 4) keeping the momentum, and 5) changing body, changing world – adapting to stay involved. Older adults perceived healthy ageing as living life with a sense of purpose and to their full potential. They engaged in a range of activities and routines, categorised into physical, social, arts, unpaid productivity and lifelong learning activities. Most had informal social groups, did not join organised activities and described motivations and strategies to adapt to changes relating to the ageing process.</div></div><div><h3>Conclusion</h3><div>These findings provide a springboard for the development of targeted intervention programs to support older adults to age well.</div></div>","PeriodicalId":8306,"journal":{"name":"Archives of gerontology and geriatrics","volume":"138 ","pages":"Article 105955"},"PeriodicalIF":3.5,"publicationDate":"2025-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144686487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of integrated care interventions on cognitive decline among older adults: A systematic review and meta-analysis","authors":"Rixin Qin ,&nbsp;Zhong Li ,&nbsp;Ling Gong ,&nbsp;Beibei Miao ,&nbsp;Yali Sun ,&nbsp;Wei Liu ,&nbsp;Li Chen","doi":"10.1016/j.archger.2025.105952","DOIUrl":"10.1016/j.archger.2025.105952","url":null,"abstract":"<div><h3>Objective</h3><div>To pool existing studies to determine the efficacy of integrated care interventions on mitigating cognitive decline among older adults.</div></div><div><h3>Design</h3><div>Systematic review with a meta-analysis of randomized controlled trials (RCTs).</div></div><div><h3>Methods</h3><div>Ten databases were searched from their inception to June 18th, 2024, with an update on November 10th, 2024. Standardized mean difference (<em>SMD</em>) was calculated using random effects models. The version 2 of the cochrane tool for assessing the risk of bias in randomized trials (RoB 2) and the Grades of Recommendation, Assessment, Development and Evaluation profiler Guideline Development Tool (GRADEpro GDT) were used to assess the methodological quality and confidence in the cumulative evidence. Funnel plots, egger's test, and begg's test were used to analyze publication bias. Sensitivity, subgroup and meta-regression analyses were performed to explore potential sources of heterogeneity.</div></div><div><h3>Results</h3><div>The results of 26 studies showed integrated care interventions had a significant effect on mitigating cognitive decline (<em>SMD</em>=0.54; <em>95 % CI</em>, 0.34 to 0.73; <em>P</em>&lt;0.001; 26 RCTs, 5615 participants; moderate-quality evidence). Subgroup analysis showed the intervention group was characterized by mean age (60–70 years old), intervention duration between 6 and 12 months, gender (female&lt;50 %), and vertical integration (VI) appeared to be more effective. Sensitivity analysis found the results to be robust.</div></div><div><h3>Conclusion</h3><div>Integrated care interventions demonstrate potential as an effective approach for addressing cognitive decline in older adults. However, further high-quality studies are necessary to enhance the certainty of evidence.</div></div>","PeriodicalId":8306,"journal":{"name":"Archives of gerontology and geriatrics","volume":"138 ","pages":"Article 105952"},"PeriodicalIF":3.5,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144679280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk factors for mortality in individuals with dementia: a systematic review and meta-analysis","authors":"Leyao Tang ,&nbsp;Ziling Feng ,&nbsp;Wenqi Liu ,&nbsp;Wenyan Zhang ,&nbsp;Yamin Liu ,&nbsp;Ni Xiong ,&nbsp;Wenhang Chen ,&nbsp;Xin Yin Wu ,&nbsp;Jianzhou Yang ,&nbsp;Wenjie Dai","doi":"10.1016/j.archger.2025.105951","DOIUrl":"10.1016/j.archger.2025.105951","url":null,"abstract":"<div><h3>Background</h3><div>Individuals with dementia had an increased risk of mortality. This systematic review aimed to comprehensively update current evidence on risk factors for mortality in individuals with dementia.</div></div><div><h3>Methods</h3><div>A database search of PubMed, Embase, Web of Science, China National Knowledge Infrastructure, Wanfang, and Chinese Scientific Journals Full-text Database was conducted from inception until October 2024. The effect size was expressed as a pooled hazard ratio (HR) and 95 % confidence interval (CI). The heterogeneity was analyzed by Cochran’s <em>Q</em> test and the <em>I²</em> statistic.</div></div><div><h3>Results</h3><div>Thirty-three eligible studies with 21 factors were included. The results showed that the risk factors for mortality in individuals with dementia were advanced age at survey (HR = 1.05, 95 % CI: 1.03–1.07), advanced age at dementia symptom onset (HR = 1.05, 95 % CI: 1.03–1.07), male sex (HR = 1.58, 95 % CI: 1.49–1.68), hypertension (HR = 1.21, 95 % CI: 1.09–1.34), diabetes (HR = 1.30, 95 % CI: 1.09–1.56), cerebrovascular disease (HR = 1.08, 95 % CI: 1.00–1.18), lung disease (HR = 1.57, 95 % CI: 1.00–2.47), higher CCI score (HR = 1.11, 95 % CI: 1.00–1.22), and higher CDR score (HR = 1.47, 95 % CI: 1.02–2.13). Non-whites (HR = 0.68, 95 % CI: 0.63–0.73), and those with depression (HR = 0.88, 95 % CI: 0.79–0.98), dyslipidemia (HR = 0.77, 95 % CI: 0.69–0.85), treatment with AChEIs (HR = 0.73, 95 % CI: 0.66–0.81), and higher MMSE score (HR = 0.95, 95 % CI: 0.94–0.97) had a lower risk.</div></div><div><h3>Conclusions</h3><div>Age at survey, age at dementia symptom onset, sex, race, hypertension, diabetes, dyslipidemia, depression, cerebrovascular disease, lung disease, CCI, AChEIs, MMSE, and CDR were associated with mortality in individuals with dementia.</div></div>","PeriodicalId":8306,"journal":{"name":"Archives of gerontology and geriatrics","volume":"137 ","pages":"Article 105951"},"PeriodicalIF":3.5,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144657090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between sleep duration and frailty in older adults: Systematic review and meta-analysis of observational studies","authors":"Hui-Min Liu ,&nbsp;Yu-Jie Xue ,&nbsp;Kai-Wen Tang ,&nbsp;Hui-Li Shen ,&nbsp;Yan Huang ,&nbsp;Wen-Yue Deng ,&nbsp;Li Qian ,&nbsp;Xue-Qin Jin","doi":"10.1016/j.archger.2025.105949","DOIUrl":"10.1016/j.archger.2025.105949","url":null,"abstract":"<div><h3>Objective</h3><div>To assess the relationship between short, and long sleep duration and the risk of frailty in older adults.</div></div><div><h3>Methods</h3><div>We conducted a systematic search of the PubMed, Web of Science, Embase, and Scopus databases, with the search completed on January 25, 2025, focusing on cross-sectional studies, case-control studies, and cohort studies regarding sleep duration and frailty risk in adults aged 60 and older. Two authors independently performed data extraction, quality assessment, and comprehensive analysis based on predefined criteria. A random effects model was used to estimate the combined effect size and 95 % confidence intervals (CIs). The I² statistic quantifies heterogeneity and explores potential sources of heterogeneity through subgroup analysis, meta-regression, and sensitivity analysis to validate the robustness of the results. A qualitative approach was used to describe studies or effect sizes that could not be analyzed quantitatively.</div></div><div><h3>Results</h3><div>This systematic review included a total of fifteen studies. In the elderly population, the prevalence of frailty was reported as 15 % among short sleepers (&lt;7 h) and 22 % among long sleepers (&gt;8 h). There was a significant association between short sleep duration(&lt;7 h) and frailty prevalence (OR1.44,95 %CI1.22–1.67), as well as a significant association between long sleep duration (&gt;8 h) and frailty prevalence (OR 1.96, 95 %CI 1.52–2.52).</div></div><div><h3>Conclusion</h3><div>In the elderly population, frailty is associated with sleep duration. Compared with those with normal sleep duration, both short and long sleepers exhibit a higher prevalence of frailty.</div></div>","PeriodicalId":8306,"journal":{"name":"Archives of gerontology and geriatrics","volume":"137 ","pages":"Article 105949"},"PeriodicalIF":3.5,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144657089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is there a relationship between hearing loss and language impairment in patients with dementia? A systematic review","authors":"L. Lodeiro-Fernández ,&nbsp;A. Maseda,&nbsp;L. Lorenzo-López,&nbsp;N. Cibeira,&nbsp;J.C. Millán-Calenti,&nbsp;J. Leira,&nbsp;S. Martínez-Ferreiro","doi":"10.1016/j.archger.2025.105948","DOIUrl":"10.1016/j.archger.2025.105948","url":null,"abstract":"<div><h3>Background</h3><div>Hearing loss (HL) and language impairment occur in the context of various types of cognitive impairment. There is extensive scientific literature on the relationship between HL and cognitive impairment or the risk of dementia, but its impact on language impairment is not well understood. This systematic review investigates the potential relationship between HL and language impairment in dementia patients.</div></div><div><h3>Method</h3><div>We conducted literature searches in the Scopus, Web of Science, and Medline databases from inception to May 2024 in accordance with PRISMA guidelines. Data extraction and methodological quality assessment, including risk of bias, were carried out.</div></div><div><h3>Results</h3><div>The search returned 767 articles for evaluation, which resulted in 14 that met the inclusion criteria. Overall, the results included 3676 older individuals, of whom 677 had dementia. Significant associations were observed between HL and language impairment, with a stronger association observed in comprehension than in production, although there was no evidence of causality.</div></div><div><h3>Conclusion</h3><div>Addressing hearing loss may play a role in managing language deficits in patients with dementia. Central auditory processing (CAP) and cognitive load are as critical as, if not more vital than, peripheral HL in language impairment in dementia patients. The quantification and directionality of the possible effects of language and hearing impairment on the genesis of dementia require longitudinal studies.</div></div>","PeriodicalId":8306,"journal":{"name":"Archives of gerontology and geriatrics","volume":"137 ","pages":"Article 105948"},"PeriodicalIF":3.5,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144604525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of social network with the incidence of frailty and depressive symptoms among older adults: a two-year longitudinal study","authors":"Tomoki Manabe ,&nbsp;Yuta Nemoto ,&nbsp;Takuya Ueda ,&nbsp;Takuya Yamada ,&nbsp;Shinichiro Sato ,&nbsp;Yoshinori Kitabatake ,&nbsp;Noriko Takeda ,&nbsp;Kazushi Maruo ,&nbsp;Takashi Arao","doi":"10.1016/j.archger.2025.105945","DOIUrl":"10.1016/j.archger.2025.105945","url":null,"abstract":"<div><h3>Background</h3><div>Social isolation, which includes a limited social networks (SN) as one of its components, is a well-known risk factor for chronic conditions, including frailty and depression. However, associations between diverse SN and these conditions are not well understood. The aim of this study was to examine the associations between SN and frailty and depressive symptoms by gender, age, and economic status.</div></div><div><h3>Methods</h3><div>A two-year longitudinal study was conducted in Tsuru City, Yamanashi, Japan. Participants included all residents aged ≥65 years without physical disability (<em>n</em> = 3327). Surveys were conducted in January 2022 and January 2024. Frailty was assessed using the Kihon Checklist, depressive symptoms were evaluated by using the Geriatric Depression Scale-15, and SN was assessed using the Lubben Social Network Scale-6. Logistic regression models were conducted to compute odds ratios (OR) and 95 % confidence intervals (CI), stratified by gender, age, and economic status.</div></div><div><h3>Results</h3><div>During the follow-up period, 15.7 % of participants developed frailty, and 10.6 % developed depressive symptoms. Older adults in the highest SN group were less likely to develop frailty (OR [95 % CI]: 0.62 [0.43, 0.88]) and depressive symptoms (OR [95 % CI]: 0.58 [0.38, 0.89]) compared with those in the lowest SN group. Those associations were more pronounced in females, individuals aged &lt;75 years, and those with poor economic status.</div></div><div><h3>Conclusions</h3><div>Older adults with larger SN are less likely to develop frailty and depressive symptoms, particularly females, those aged &lt;75 years, and those with poor economic status. This provides useful insights for future interventions.</div></div>","PeriodicalId":8306,"journal":{"name":"Archives of gerontology and geriatrics","volume":"137 ","pages":"Article 105945"},"PeriodicalIF":3.5,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144657091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of smoking on age-related deterioration in hearing: A cohort study using health checkups","authors":"Kensuke Uraguchi ,&nbsp;Akiko Sugaya ,&nbsp;Etsuji Suzuki ,&nbsp;Naomi Matsumoto ,&nbsp;Eriko Yanagi ,&nbsp;Soshi Takao ,&nbsp;Takashi Yorifuji ,&nbsp;Mizuo Ando","doi":"10.1016/j.archger.2025.105947","DOIUrl":"10.1016/j.archger.2025.105947","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to investigate the association between smoking status and hearing loss, both at baseline and annually, using longitudinal health checkup data.</div></div><div><h3>Methods</h3><div>We analyzed data from 2349 participants (9250 health checkups) aged 20 years and older who underwent comprehensive health checkups at Takinomiya General Hospital in Kagawa, Japan, between 2015 and 2023. Hearing thresholds at 1.0 kHz and 4.0 kHz were measured using pure-tone audiometry, where higher thresholds indicate worse hearing. Smoking status was categorized as never-smoker, past smoker, or current smoker (&lt;10 or ≥10 cigarettes/day). Multilevel linear regression models adjusted for age, sex, occupation, and medical history were used to assess baseline differences and annual changes in hearing thresholds.</div></div><div><h3>Results</h3><div>At 1.0 kHz, smoking was not significantly associated with hearing thresholds. However, at 4.0 kHz, current smokers (≥10 cigarettes/day) had worse baseline hearing, with an adjusted threshold increase of 2.51 dB compared with never-smokers (<em>p</em> &lt; 0.01). Additionally, past smokers and current smokers (≥10 cigarettes/day) experienced significantly faster deterioration in hearing annually at 4.0 kHz, with reductions of 0.73 dB/year (<em>p</em> &lt; 0.01) and 0.78 dB/year (<em>p</em> &lt; 0.01), respectively.</div></div><div><h3>Discussion</h3><div>These findings suggest that smoking is associated with high-frequency hearing impairment and may contribute to accelerated age-related hearing loss. The effect of smoking cessation was not evident in past smokers, and further studies are warranted to examine this hypothesis.</div></div>","PeriodicalId":8306,"journal":{"name":"Archives of gerontology and geriatrics","volume":"137 ","pages":"Article 105947"},"PeriodicalIF":3.5,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144597520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of interventions to improve frailty among community-dwelled older adults: A systematic review","authors":"Yongyi Guan ,&nbsp;Zhiyun Hu ,&nbsp;Qian Wang ,&nbsp;Renlun Ou ,&nbsp;Hui Xue ,&nbsp;Wei Du ,&nbsp;Lijun Fan","doi":"10.1016/j.archger.2025.105946","DOIUrl":"10.1016/j.archger.2025.105946","url":null,"abstract":"<div><h3>Background</h3><div>Frailty, a geriatric syndrome linked to adverse outcomes, is a significant public health concern in aging populations. This systematic review synthesizes evidence on the effectiveness of interventions, grouped by their components, to reduce frailty in community-dwelling older adults.</div></div><div><h3>Methods</h3><div>Major biomedical databases were searched for relevant intervention studies from inception to 24 October 2024. Dual screening, data extraction, risk assessment, and synthetic analysis were conducted. Interventions were classified into discrete characteristic components based on the key intervention features identified in the included studies. Findings on effectiveness of interventions were narratively synthesized owing to heterogeneity.</div></div><div><h3>Results</h3><div>This review included 62 studies (32,364 participants; 76 interventions). Most interventions were multidimensional, and multimodal interventions were found to be effective in improving frailty. The standalone approach of multicomponent or two-component exercise showed potential benefits, while single-component exercise was less likely to be effective. Studies on single-component interventions other than exercise were limited, with mixed results: Nutritional supplements, nutrition guides, art-based activities, and pharmacological agents showed limited efficacy as standalone strategies. Comprehensive educational programs, medical-related care, and cognitive training were scarcely studied but suggested favorable effects on frailty indicators. Limited economic evidence supported cost-effectiveness or cost-saving of interventions addressing frailty.</div></div><div><h3>Conclusions</h3><div>Current frailty interventions for older residents in the community predominantly relied on exercise or physical activity. Future research should prioritize exploring optimal intervention components or combinations and developing comprehensive intervention strategies, to achieve precise and sustainable improvements in frailty among the broader community-based older populations.</div></div>","PeriodicalId":8306,"journal":{"name":"Archives of gerontology and geriatrics","volume":"137 ","pages":"Article 105946"},"PeriodicalIF":3.5,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144633470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing the incidence rates of dementia: Association of social participation among older adults in Japan","authors":"Satoko Fujihara ,&nbsp;Ryota Watanabe ,&nbsp;Taishi Tsuji ,&nbsp;Yasuhiro Miyaguni ,&nbsp;Katsunori Kondo","doi":"10.1016/j.archger.2025.105944","DOIUrl":"10.1016/j.archger.2025.105944","url":null,"abstract":"<div><div>Social participation is associated with reduced dementia risk and has recently increased in Japan, which may be related to changes in dementia incidence rates. This study compared dementia incidence rates between two cohorts of older Japanese adults across five municipalities and examined whether differences were associated with social participation or social participation-related variables. We analyzed data from the Japan Gerontological Evaluation Study, comprising two three-year follow-up cohorts (2013–2016: <em>n</em> = 25,281; 2016–2019: <em>n</em> = 26,284) of community-dwelling adults aged ≥ 65 years not certified for long-term care. Survival analysis was performed to calculate hazard ratios for dementia, using cohort and social participation as explanatory variables. Analyses were stratified by age (65–74 and ≥ 75 years) and adjusted for demographics, social participation, and social participation-related variables. Dementia incidence declined from 149.7 to 131.3 per 10,000 person-years between cohorts. The sex- and age-adjusted hazard ratios for the 2016–2019 cohort (reference: 2013–2016) were 0.83 (95 % CI: 0.67, 1.03) for ages 65–74 and 0.83 (95 % CI: 0.75, 0.91) for ≥ 75 years. After adjusting for social participation and social participation-related variables, the cohort difference became non-significant in the ≥ 75 years group (hazard ratio: 0.99; 95 % CI: 0.89, 1.09). This decline in dementia incidence rates among those aged ≥ 75 years may be associated with social participation and related variables. These findings suggest a potential association between social participation and lower dementia incidence rates; however, further research is needed to confirm these results.</div></div>","PeriodicalId":8306,"journal":{"name":"Archives of gerontology and geriatrics","volume":"137 ","pages":"Article 105944"},"PeriodicalIF":3.5,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144632382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Age-related changes in anthropometric measurements, body composition, and physical function among middle-aged and older Japanese community-dwellers: A longitudinal study","authors":"Rei Otsuka ,&nbsp;Shu Zhang ,&nbsp;Yukiko Nishita ,&nbsp;Sayaka Kubota ,&nbsp;Chikako Tange ,&nbsp;Hiroshi Shimokata ,&nbsp;Hiroshi Yatsuya","doi":"10.1016/j.archger.2025.105943","DOIUrl":"10.1016/j.archger.2025.105943","url":null,"abstract":"<div><h3>Objective</h3><div>To quantify annual changes and develop population-normalized aging curves for height, body weight, and grip strength according to specific birth cohorts.</div></div><div><h3>Methods</h3><div>This longitudinal study analyzed data from the National Institute for Longevity Sciences – Longitudinal Study of Aging, following 1901 community-dwelling adults aged 40−79 years for up to 12 years. Annual changes in height, body weight, body mass index (BMI), body fat percentage, skeletal muscle mass, and grip strength were assessed by sex using linear mixed-effects models. Birth cohort-specific reference values according to sex were developed using participants who participated in at least one wave between 1997 and 2022 (<em>n</em> = 1990) with generalized additive mixed models.</div></div><div><h3>Results</h3><div>Significant negative follow-up years × age interactions were observed for height, body weight, BMI, skeletal muscle mass, and grip strength in men (all <em>p</em>-values &lt; 0.001) and for height, body weight, BMI, body fat percentage, and skeletal muscle mass in women (all <em>p</em>-values &lt; 0.01). Grip strength began declining preceding any significant change in other indicators. For height and grip strength, birth cohort-specific reference values for age-related changes showed a gradual decline with age in both sexes, with more recent birth cohorts being consistently taller but having weaker grip strength than earlier cohorts. Men experienced slight weight increases until ages 60−70 years, followed by a decline. Women maintained a stable weight until age 60 years before declining.</div></div><div><h3>Conclusions</h3><div>These reference values provide evidence-based tools for detecting age-related changes in body composition and function among relatively healthy participants and guiding preventive interventions in clinical and community settings.</div></div>","PeriodicalId":8306,"journal":{"name":"Archives of gerontology and geriatrics","volume":"137 ","pages":"Article 105943"},"PeriodicalIF":3.5,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144563198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}