Archives of Osteoporosis最新文献

{"title":"Total, dietary, and supplemental calcium intake and risk of all-cause, cardiovascular, and cancer mortality among U.S. adults: a prospective cohort study from the National Health and Nutrition Examination Survey","authors":"Ran Chen,&nbsp;Ying Tang,&nbsp;Shunzheng Fang,&nbsp;Kai Gong,&nbsp;Dong Liu,&nbsp;Yu Xie,&nbsp;Guo Liu,&nbsp;Yu Tian,&nbsp;Lianyang Zhang,&nbsp;Yang Li,&nbsp;Siru Zhou","doi":"10.1007/s11657-024-01457-5","DOIUrl":"10.1007/s11657-024-01457-5","url":null,"abstract":"<div><h3>Summary</h3><p>Calcium intake is widely recommended, but its association with mortality remains unclear. This study indicated higher levels of calcium intake were associated with lower mortality in American adults. However, a nonlinear association between calcium intake and mortality suggested that excessive calcium intake beyond a certain threshold may increase mortality risk.</p><h3>Purpose</h3><p>The study aimed to investigate the association of total, dietary, or supplemental calcium intake with all-cause, cardiovascular, and cancer mortality in American adults.</p><h3>Methods</h3><p>This prospective cohort study used the National Health and Nutrition Examination Survey from 2005 to 2018. Participants were categorized into tertiles based on calcium intake. Risks of all-cause, cancer, or cardiovascular mortality and the dose–response relationship were estimated using weighted Cox proportional hazard regression and restricted cubic splines, with adjustments for demographic characteristics, comorbidities, laboratory parameters, and dietary data.</p><h3>Results</h3><p>In total, 6172 participants were included (median age: 61 years), and 869 had died (CVD:217, cancer:224) during a median follow-up of 81 months. After adjusting for confounders, higher total calcium(≥ 1660mg/d) [HR, 95%CI: 0.867 (0.865–0.869)], dietary calcium(≥ 1075mg/d) [HR, 95%CI: 0.711 (0.709–0.713)], and supplemental calcium (≥ 600mg/d) [HR, 95%CI: 0.786 (0.784–0.787)] intake groups were associated with lower all-cause mortality risk compared to the lowest intake group. Similar beneficial associations were found for cardiovascular, cancer mortality, and across subgroups of various ages, genders, races and body mass indexes. In the dose–response analysis, a 'J-shaped' nonlinear relationship was observed between calcium intake and the risk of all-cause, cardiovascular, and cancer mortality.</p><h3>Conclusions</h3><p>Higher levels of total, dietary, or supplemental calcium were associated with lower all-cause, cardiovascular, or cancer mortality. However, a nonlinear association between calcium intake and mortality suggested that excessive calcium intake beyond a certain threshold may increase mortality risk.</p></div>","PeriodicalId":8283,"journal":{"name":"Archives of Osteoporosis","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142600815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dietary recommendations of the Moroccan Society of Rheumatology (SMR) for patients with ostéosarcopenia","authors":"S. Zemrani,&nbsp;S. Rostom,&nbsp;H. El kasmi,&nbsp;B. Amine,&nbsp;L. Tahiri,&nbsp;N. Akasbi,&nbsp;K. Nassar,&nbsp;R. Lahlou,&nbsp;N. Bensaoud,&nbsp;S. Mehdioui,&nbsp;S. Ouakrim,&nbsp;R. Bahiri","doi":"10.1007/s11657-024-01461-9","DOIUrl":"10.1007/s11657-024-01461-9","url":null,"abstract":"<div><h3>Objective</h3><p>The objective of this study was to develop the first Moroccan recommendations concerning nutrition in patients with osteosarcopenia.</p><h3>Material and methods</h3><p>A steering committee consisting of rheumatologists and nutritionists drafted the initial version of the recommendations in light of the literature review and the recommendations of international societies. The draft was reviewed by a reading committee of 13 experts to approve the final version.</p><h3>Results</h3><p>Four overarching principles and ten recommendations were established. The overarching principles emphasize that nutritional advice is not a substitute for the pharmacological treatment of osteosarcopenia. Instead, it should be based on scientific evidence and take into account the specific characteristics of Moroccan society. The recommendations emphasize the significance of adequate calcium and vitamin D intake while evaluating the benefit-risk ratio in instances where calcium supplementation is indicated. A balanced intake of trace elements, vitamins, proteins, and dairy products should be maintained. The Mediterranean diet is recommended, while vegetarian diets and restrictive diets in individuals who are not overweight are not advised. It is recommended that individuals who fast during Ramadan consume a varied and balanced diet. It is recommended that the consumption of soft drinks and alcohol be limited. The consumption of phytoestrogens from food in moderation is considered beneficial as part of a balanced diet. Nevertheless, the use of supplements is not advised.</p><h3>Conclusion</h3><p>The purpose of this work is to provide Moroccan rheumatologists with a practical tool to improve the nutritional aspect in patients with osteosarcopenia.</p></div>","PeriodicalId":8283,"journal":{"name":"Archives of Osteoporosis","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142596066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trabecular bone score as an assessment tool to identify the risk of vertebral fractures in SAPHO syndrome","authors":"Zaizhu Zhang,&nbsp;Yi Zhang,&nbsp;Wei Yu","doi":"10.1007/s11657-024-01472-6","DOIUrl":"10.1007/s11657-024-01472-6","url":null,"abstract":"<div><h3>\u0000 <i>Summary</i>\u0000 </h3><p>This is the first study to report that TBS seems not only unaffected by bone artifacts, but also is superior to BMD in the discrimination of vertebral fractures in SAPHO patients, which highlights the importance of adding TBS measurement to DXA images in routine clinical evaluation.</p><h3>Purpose</h3><p>To investigate the impact of bone artifacts on trabecular bone score (TBS) and lumbar spine (LS) bone mineral density (BMD) measured by dual-energy X-ray absorptiometry (DXA) and analyze the clinical utility of TBS evaluation for vertebral fracture (VF) risk assessment in SAPHO patients compared with BMD assessment.</p><h3>Methods</h3><p>Seventy SAPHO patients (mean age 50.1 (10.7) years, 81% women) and an equal number of age- and sex-matched controls were enrolled. TBS and BMD were assessed using DXA. Bone artifacts and VF of the spine were evaluated using whole-spine CT. Univariate logistic regression analysis was performed to identify factors associated with VF. Odds ratios (ORs) per standard deviation decrease in TBS and BMDs were estimated from logistic regression models with adjustment for age.</p><h3>Results</h3><p>In patients with bone artifacts, TBS, but not LS BMD, was lower than matched controls, and in those without bone artifacts, both BMDs and TBS were lower than controls. After adjustment, LS BMD was significantly lower in the SAPHO group than in controls. TBS and LS BMD (OR [95% confidence interval], 12.0 [3.6, 40.4] and 4.7 [2.0, 10.9]) showed statistically significant ORs but the others did not. For evaluating VF in SAPHO patients, TBS showed the greatest AUC in the ROC curve, with a value of 0.920 compared with 0.777, 0.690, and 0.652 for LS, FN, and TH BMD, respectively.</p><h3>Conclusion</h3><p>TBS seems not to be influenced by bone artifacts in opposition to LS BMD and has a better discriminatory value than BMD for VF in SAPHO patients.</p></div>","PeriodicalId":8283,"journal":{"name":"Archives of Osteoporosis","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142596090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Osteoporosis incidence and its associated factors in the older Korean population: findings from a population-based cohort study","authors":"Tanmoy Das,&nbsp;Md Abdullah Al Jubayer Biswas,&nbsp;Prosanta Mondal,&nbsp;Sabuj Sarker,&nbsp;Hyun J.“June” Lim","doi":"10.1007/s11657-024-01466-4","DOIUrl":"10.1007/s11657-024-01466-4","url":null,"abstract":"<div><h3>Summary</h3><p>In South Korea, osteoporosis incidence among the elderly was unclear. Our study revealed an incidence of 18.4 per 1000 person-years, with higher rates in females and those with lower education. The findings indicate a need for targeted prevention strategies to guide health policy for improved osteoporosis care for the elderly.</p><h3>Background</h3><p>Although osteoporosis significantly affects morbidity and mortality among the older population in South Korea, the incidence of osteoporosis and its associated factors within this demographic group remains unclear.</p><h3>Method</h3><p>We analyzed data from the Korean National Health Panel Survey, a nationally representative, population-based panel survey covering 2008 to 2018, to compute the incidence of osteoporosis among South Koreans aged 50 and older. Using the stepwise Cox Proportional Hazard model, we then identified and determined the associated factors of osteoporosis.</p><h3>Result</h3><p>Out of the 7304 study participants in our analysis, we identified 792 osteoporosis events, resulting in an overall cumulative incidence rate of 18.4 per 1000 person-years. The incidence of osteoporosis increased steadily with age and was higher among those with lower levels of education. We also found that female study participants were at a statistically significant 7.2-fold higher risk (aHR = 7.2, 95% CI = 5.8–8.8) of developing osteoporosis compared to males. At the same time, those with hyperlipidemia had a statistically significant 1.3-fold increased risk (aHR = 1.3, 95% CI = 1.1–1.4) of developing osteoporosis.</p><h3>Conclusion</h3><p>Our study highlights a significant proportion of the older South Korean population developed osteoporosis, especially among those who are older, females, and who have hyperlipidemia. This indicates the pressing need for the government’s and healthcare systems’ consideration of osteoporosis diagnosis and prevention strategies to ensure the health and well-being of the older South Korean population.</p></div>","PeriodicalId":8283,"journal":{"name":"Archives of Osteoporosis","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142596053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Estimated frequency and economic burden of incident fragility fractures during 2023 in Mexico","authors":"Fernando Carlos-Rivera,&nbsp;Jorge Antonio Guzmán-Caniupan,&nbsp;Luis Miguel Camacho-Cordero,&nbsp;Therese Aubry de Maraumont,&nbsp;Noe Soria-Suárez","doi":"10.1007/s11657-024-01468-2","DOIUrl":"10.1007/s11657-024-01468-2","url":null,"abstract":"<div><h3>\u0000 <i>Summary</i>\u0000 </h3><p>Epidemiologic and economic data regarding osteoporotic fractures in Mexico is scarce and mostly outdated. Through a model, we estimated the incidence and costs of osteoporotic fractures in adults ≥ 50 years old in Mexico during the year 2023. Results showed that these events are both frequent and costly, leading to a considerable economic impact.</p><h3>Purpose</h3><p>Osteoporosis and its fractures impose a high clinical and economic burden. The objective of this analysis was to estimate the frequency and costs owing to incident fragility fractures (FFs) during the year 2023 in Mexico.</p><h3>Methods</h3><p>This is an incidence-based cost-of-illness study. The target population is adults ≥ 50 years old sustaining a fracture related to osteoporosis (caused by a fall on the same level). The model estimates the costs and productivity losses associated with their treatment within 1 year post-fracture. National epidemiologic databases supplemented with information, derived from literature when appropriate, were used to estimate the frequency of new FFs during 2023 in the study population. Resource use included surgical and non-surgical inpatient or ambulatory care the patients received immediately after fracture plus the outpatient physiotherapy post-discharge and the eventual follow-up with a specialist who may prescribe pharmacotherapy. Sick days taken in employed patients were estimated from the literature. Local unitary costs of services and drugs for both public and private settings as well as average income in those occupied were applied. All costs are reported in Mexican pesos (MXN) from 2023.</p><h3>Results</h3><p>The model estimated a total of 229,239 FFs, among which 63% were classified as a major osteoporotic fracture, including 53,842 and 41,459 fractures located at the hip and vertebral, respectively. The total costs were estimated at 15,593 million MXN; most of them (75.2%) were attributable to acute-phase care.</p><h3>Conclusions</h3><p>Fragility fractures represent a serious health problem for Mexico. Better preventive/therapeutic strategies may help to mitigate their significant financial toll.</p></div>","PeriodicalId":8283,"journal":{"name":"Archives of Osteoporosis","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s11657-024-01468-2.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142589681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hip structure and incident fracture: a time-updating survival analysis over 20 years of data from the Geelong Osteoporosis Study","authors":"Kara B. Anderson,&nbsp;Mohammadreza Mohebbi,&nbsp;Monica C. Tembo,&nbsp;Pamela Rufus-Membere,&nbsp;Natalie K. Hyde,&nbsp;Julie A. Pasco,&nbsp;Mark A. Kotowicz,&nbsp;Kara L. Holloway-Kew","doi":"10.1007/s11657-024-01471-7","DOIUrl":"10.1007/s11657-024-01471-7","url":null,"abstract":"<div><h3>\u0000 <i>Summary</i>\u0000 </h3><p>Hip structural analysis parameters are associated with risk of fracture in women across a long follow-up period, with buckling ratio persisting independent of total hip BMD.</p><h3>Purpose</h3><p>Hip structural analysis (HSA) uses dual X-ray absorptiometry (DXA) hip scans to calculate geometries of narrow neck (NN), intertrochanter (IT), and shaft (S), which may complement bone mineral density (BMD) for assessing fracture risk. We aimed to determine whether HSA parameters were associated with fracture.</p><h3>Methods</h3><p>Participants were women (<i>n</i> = 986, ages 40–94 year) from the Geelong Osteoporosis Study. HSA was calculated from Lunar DPX-L scans. Low-trauma incident fractures were identified radiologically. Participants were followed from baseline to first fracture, death, or end of follow-up period (31/12/16) (13,487 person-years follow-up). Time-updating Cox-proportional hazards modelling investigated associations between HSA parameters and fracture.</p><h3>Results</h3><p>Three hundred thirty-five participants reported fractures (rate: 24.99/1000 person-years [95% CI 22.46–27.80]). Higher NN BMD (HR:0.12, 95% CI:0.05–0.29), cross-sectional area (CSA) (0.37, 0.26–0.52), cross-sectional moment of inertia (CSMI) (0.66, 0.50–0.89), section modulus (SM) (0.40, 0.24–0.68) and cortical thickness (CT) (0.00, 0.00–0.01 due to rounding) were associated with decreased risk. IT BMD (0.08, 0.04–0.20), CSA (0.58, 0.49–0.69), CSMI (0.90, 0.85–0.94), and SM (0.69, 0.59–0.81) were similarly associated. Decreased risk was observed at increased values of S BMD (0.20, 0.10-0.38), CSA (0.60, 0.47–0.76), SM (0.60, 0.43–0.83), and CT (0.03, 0.01–0.14). Higher S endocortical diameter (1.81, 1.29–2.53), and buckling ratio (BR) at all sites (NN: 1.07, 1.04-1.11; IT: 1.08, 1.05–1.11, S: 1.31, 1.19–1.46) were associated with increased risk. After adjustment for total hip BMD, the associations with BR at the shaft (1.14, 1.00–1.30) were sustained. Other associations were attenuated.</p><h3>Conclusion</h3><p>A greater shaft buckling ratio was associated with an increased risk for fracture, independent of total hip BMD.</p></div>","PeriodicalId":8283,"journal":{"name":"Archives of Osteoporosis","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142595406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing comprehension and fostering involvement in the fracture liaison services system in Türkiye: a call for action","authors":"Mustafa Hüseyin Temel,&nbsp;Fatih Bağcıer,&nbsp;Şansın Tüzün","doi":"10.1007/s11657-024-01473-5","DOIUrl":"10.1007/s11657-024-01473-5","url":null,"abstract":"","PeriodicalId":8283,"journal":{"name":"Archives of Osteoporosis","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142589662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic nutritional index (PNI) is an independent predictor for functional outcome after hip fracture in the elderly: a prospective cohort study","authors":"Yimin Chen,&nbsp;Mingjian Bei,&nbsp;Gang Liu,&nbsp;Jing Zhang,&nbsp;Yufeng Ge,&nbsp;Zhelun Tan,&nbsp;Weidong Peng,&nbsp;Feng Gao,&nbsp;Chao Tu,&nbsp;Maoyi Tian,&nbsp;Minghui Yang,&nbsp;Xinbao Wu","doi":"10.1007/s11657-024-01469-1","DOIUrl":"10.1007/s11657-024-01469-1","url":null,"abstract":"<div><h3>\u0000 <i>Summary</i>\u0000 </h3><p>The prognostic nutritional index (PNI) is a useful tool for assessing nutritional status using serum albumin and lymphocyte count. This study indicates that a higher preoperative PNI correlates with improved mobility and health-related quality of life during the initial postoperative period in elderly patients with hip fractures.</p><h3>Purpose</h3><p>To investigate the prognostic value of the prognostic nutritional index (PNI) in predicting mobility and health-related quality of life (HRQoL) in elderly hip fracture patients after surgery.</p><h3>Methods</h3><p>We prospectively involved patients aged 65 and above, who could walk freely before injury and underwent surgery between 2018 and 2019. Admission PNI was calculated as serum albumin (g/L) + 5 × total lymphocyte count (× 10⁹/L). Patients were classified into two groups based on PNI median value. All patients were followed up by telephone for four times (30-day, 120-day, 1-year, and 3-year after surgery). The Fracture Mobility Score (FMS) and EuroQol 5-Dimension 5-Level (EQ-5D 5L) were used to evaluate mobility and HRQoL, respectively.</p><h3>Results</h3><p>Of 705 eligible patients, 487 completed all assessments. Patients in the higher PNI group had a significantly increased possibility of achieving unrestricted mobility at the 120-day follow-up (OR 1.69, 95% CI 1.10–2.61, P.adj = 0.017), while no significant differences were observed at other follow-ups. Additionally, patients in the higher PNI group had a significantly higher EQ-5D utility value at the 30-day follow-up (P.adj = 0.015). A linear regression model with adjusting for all confounders showed that admission PNI value was positively associated with EQ-5D utility values at 30-day, 120-day, and 1-year follow-up assessments (P.adj = 0.011, P.adj = 0.001, and P.adj = 0.030, respectively). However, this correlation was not observed at the 3-year time point (P.adj = 0.079).</p><h3>Conclusion</h3><p>The PNI is a valuable predictor of functional outcomes in elderly patients with hip fractures following surgery.</p></div>","PeriodicalId":8283,"journal":{"name":"Archives of Osteoporosis","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s11657-024-01469-1.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142579498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Geographical variation in osteoporosis in Australian women: a longitudinal analysis over 23 years","authors":"A. R. Jones,&nbsp;J. Enticott,&nbsp;P. R. Ebeling,&nbsp;G. D. Mishra,&nbsp;H. J. Teede,&nbsp;A. J. Vincent","doi":"10.1007/s11657-024-01463-7","DOIUrl":"10.1007/s11657-024-01463-7","url":null,"abstract":"<div><h3>\u0000 <i>Summary</i>\u0000 </h3><p>Osteoporosis affects over half of older women, whether urban compared to rural residents have different risk of osteoporosis is unclear. This 23-year longitudinal study of Australian women found lower risk of osteoporosis and fractures among women living in rural compared with urban areas, which may relate to distribution of risk factors and/or screening opportunities.</p><h3>Purpose</h3><p>To determine whether the prevalence of osteoporosis, fractures, and dual-X-ray absorptiometry (DXA) differs between Australian women living in rural compared with urban areas.</p><h3>Methods</h3><p>The Australian Longitudinal Study on Women’s Health, a prospective longitudinal study of Australian women, includes a cohort of women born 1946–1951, surveyed nine times from 1996–2019. Data from administrative health records were linked to survey data. Geographic area was classified as major city, inner regional, outer regional, or remote. Generalised estimating equations (GEE) explored outcomes of osteoporosis, fracture, and DXA rates. Univariable and multivariable regression were performed and bootstrapping with 100 repetitions at 95% sampling of the original dataset to ensure robust results.</p><h3>Results</h3><p>A total of 13,712 women were included: 5000 (36.5%) living in major cities, 5214 (38.0%) inner regional, 2798 (20.41%) outer regional, and 700 (5.1%) remote areas. Baseline age, 47.6 (1.46) years (mean (SD)), was similar; but education, marital status, country of birth, smoking, BMI, and comorbidities varied between areas. Over 23 years, 2956 (21.6%) were diagnosed with osteoporosis, 3185 (23.2%) had an incident fracture, and 8151 (59.4%) had a DXA. On univariable analysis, women living outside major cities had lower risk of osteoporosis (inner regional OR 0.92; 95% CI 0.84, 0.99; outer regional 0.70; 0.63, 0.79; remote 0.43; 0.34, 0.53), and lower risk of fractures (inner regional area OR 0.92, 95% CI 0.84, 0.99; outer regional 0.81; 0.73, 0.90; remote 0.54; 0.42, 0.67), than women living in major cities. These differences were no longer significant on multivariable analysis, suggesting differences might be related to the distribution of risk factors. Women living in inner regional and outer regional areas were significantly less likely to have a DXA, than those living in a major city (OR 0.75, 95% CI 0.70, 0.81; OR 0.72; 95% CI 0.64, 0.77, respectively), and this remained significant on multivariable analysis.</p><h3>Conclusion(s)</h3><p>Osteoporosis or fracture affected one-third of older Australian women, and women living outside major cities had lower rates of osteoporosis, fractures, and DXA completion.</p></div>","PeriodicalId":8283,"journal":{"name":"Archives of Osteoporosis","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142575045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: The correlation between circulating growth differentiation factor 11 and the risk of osteopenia/osteoporosis in men","authors":"Miaomiao Jin,&nbsp;Renjun Cao,&nbsp;Xiaohong Niu,&nbsp;Pengfei Shan","doi":"10.1007/s11657-024-01464-6","DOIUrl":"10.1007/s11657-024-01464-6","url":null,"abstract":"","PeriodicalId":8283,"journal":{"name":"Archives of Osteoporosis","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142540803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}