Archives of Osteoporosis最新文献

{"title":"Trends of incidence and 1-year mortality of vertebral fractures in Korea using nationwide claims data","authors":"Young-Kyun Lee,&nbsp;Jung-Wee Park,&nbsp;Tae-Young Kim,&nbsp;Jihye Kim,&nbsp;Hoyeon Jang,&nbsp;Jaiyong Kim,&nbsp;Yong-Chan Ha","doi":"10.1007/s11657-025-01621-5","DOIUrl":"10.1007/s11657-025-01621-5","url":null,"abstract":"<div><h3>\u0000 <i>Summary</i>\u0000 </h3><p>Using nationwide data from 2006 to 2022, we found that vertebral fracture rates in Korea plateaued recently, with a slight decline during COVID-19, while one-year mortality remained unchanged. These findings highlight the growing burden of osteoporotic fractures and underscore the need for targeted prevention and management strategies.</p><h3>Purpose</h3><p>Our purposes were to evaluate the trends in the incidence and mortality of vertebral fractures and the effects of COVID-19 between 2006 and 2022 in Korea, using nationwide data from the National Health Insurance Service (NHIS).</p><h3>Methods</h3><p>A nationwide dataset was evaluated to identify all new visits to medical institutes for vertebral fractures in men and women aged 50 years or older between 2006 and 2022. Patients were defined using ICD-10 diagnosis codes combined with procedure codes to ensure specificity. The incidence and 1-year mortality rates were calculated. The age- and sex-standardized incidence rates were calculated using the 2020 Korean population as the reference, which demonstrated a plateauing trend in recent years.</p><h3>Results</h3><p>While the number of vertebral fractures increased, the incidence plateaued around 2010. Men and women respectively experienced 17,872 and 66,980 vertebral fractures in 2006 and 43,901 and 136,826 in 2022. The crude incidence of vertebral fractures changed from 319.4/100,000 to 408.5/100,000 person-years in men and 1011.1/100,000 to 1155.5/100,000 person-years in women between 2006 and 2022. The 1-year mortality rate after vertebral fractures gradually decreased from 6.5% in 2006 to 6.2% in 2021. There was no remarkable change of mortality during the outbreak of COVID-19. The overall mortality of vertebral fractures in men was about twice as high women as during the whole study period.</p><h3>Conclusion</h3><p>The incidence of vertebral fractures remained relatively stable after 2010 in Korea. During the outbreak of COVID-19, incidence of vertebral fractures decreased while the mortality after vertebral fractures was unaffected.</p></div>","PeriodicalId":8283,"journal":{"name":"Archives of Osteoporosis","volume":"20 1","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145342975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A machine-learning-based osteoporosis screening tool integrating the Shapley Additive exPlanation (SHAP) method: model development and validation study","authors":"Yuji Zhang,&nbsp;Ming Ma,&nbsp;Cong Tian,&nbsp;Jinmin Liu,&nbsp;Zhenkun Duan,&nbsp;Xingchun Huang,&nbsp;Bin Geng","doi":"10.1007/s11657-025-01602-8","DOIUrl":"10.1007/s11657-025-01602-8","url":null,"abstract":"<div><h3>Summary</h3><p>Rationale: Existing osteoporosis screening tools are inaccurate and inconvenient, prompting the need for a better alternative.</p><p>Main result: A machine learning tool (Gradient Boosting) with key factors (weight, age, height) outperformed OST (AUC 0.828 vs 0.781, <i>p</i> &lt; 0.0001) in validation.</p><h3>Significance</h3><p>The validated, clinically applicable tool improves osteoporosis screening accessibility and accuracy.</p><h3>Background</h3><p>As the first “line of defence” for osteoporosis detection, existing screening tools have low accuracy and are inconvenient to use. Therefore, this study aims to develop a machine-learning-based, clinically applicable, and interpretable osteoporosis screening tool.</p><h3>Methods</h3><p>This study included 9405 American participants aged 50 years and older (with the average age of the osteoporosis population in the training set and test set being 72 ± 9 years and 73 ± 8 years, respectively). The study selected 13 clinically accessible indicators as candidate predictive variables, divided the data into a training set and a test set at a ratio of 7:3, used the Lasso for feature selection, compared six statistical and machine learning models, evaluated model performance through metrics such as the Area Under the Receiver Operating Characteristic Curve (AUC), Sensitivity, specificity, F1-score, decision curve, calibration curve, and clinical impact curve, employed the SHAP (Shapley Additive exPlanations) method to enhance model interpretability, and conducted external validation based on an independent dataset from the Second Hospital of Lanzhou University.</p><h3>Results</h3><p>“Weight,” “age,” and “height” are the most critical predictive factors. Gradient Boosting Machine (GB) showed optimal results, with training and test set AUC (0.850, 0.841), sensitivity (0.757, 0.737), specificity (0.793, 0.779), and F1-score (0.336, 0.316), respectively. External validation (3500 subjects) showed that the GB-based screening tool had an AUC of 0.828, which was significantly higher than that of the traditional Osteoporosis Self-Assessment Tool (OST, AUC = 0.781) via the DeLong test (z = 10.880, <i>p</i> &lt; 0.0001).</p><h3>Conclusion</h3><p>A clinically applicable osteoporosis screening tool based on machine learning algorithms was developed and validated.</p></div>","PeriodicalId":8283,"journal":{"name":"Archives of Osteoporosis","volume":"20 1","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145342960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bariatric surgery: Think about osteomalacia too","authors":"Anastasia Mocritcaia,&nbsp;Chafik Chacur,&nbsp;Helena Flórez,&nbsp;Ana Monegal,&nbsp;Núria Guañabens,&nbsp;Pilar Peris","doi":"10.1007/s11657-025-01618-0","DOIUrl":"10.1007/s11657-025-01618-0","url":null,"abstract":"<div><h3>Summary</h3><p>Around 9% of patients with previous bariatric surgery referred for osteoporosis treatment may have osteomalacia. Increased serum total alkaline phosphatase values should alert clinicians to this diagnosis since it requires a differential treatment approach, with some patients needing high doses of calcium or even parenteral vitamin D supplementation.</p><h3>Introduction</h3><p>The development of osteoporosis and fractures is a well-documented complication of bariatric surgery (BS). Nevertheless, subjects undergoing BS can also develop osteomalacia, which can be easily misdiagnosed as osteoporosis.</p><h3>Objectives</h3><p>To analyze the prevalence of osteomalacia and the main clinical characteristics of subjects with previous BS referred to a Rheumatology Department for osteoporosis treatment.</p><h3>Methods</h3><p>This retrospective study included a cohort of 46 subjects (aged 42–77 years) with previous BS referred for osteoporosis treatment. Clinical data were obtained from a review of medical records, including the type and time since surgery, treatment with calcium and/or vitamin D, and clinical, laboratory, radiologic, and densitometric data. Osteomalacia was diagnosed by compatible bone biopsy and/or clinical criteria (two of the following: low calcium, low phosphate, elevated total alkaline phosphatase [TAP], or suggestive radiology).</p><h3>Results</h3><p>Four out of 46 patients (8.7%) presented osteomalacia criteria; most were women (3/4) treated with malabsorptive surgery (from 4 to 13 years previously). All presented increased serum TAP and parathyroid hormone values, and most presented hypocalcemia and low vitamin D levels. Bone scan was compatible with osteomalacia in most subjects, and all subjects presented densitometric osteoporosis, with most developing fractures/pseudofractures after BS. No subject was referred to our department with clinical suspicion of osteomalacia.</p><h3>Conclusions</h3><p>Nearly 9% of patients with previous BS referred for osteoporosis treatment may have osteomalacia. Increased serum TAP values should alert clinicians to this diagnosis since it requires a differential treatment approach, with some patients needing high doses of calcium or even parenteral vitamin D supplementation.</p></div>","PeriodicalId":8283,"journal":{"name":"Archives of Osteoporosis","volume":"20 1","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145285291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Opportunistic screening of low bone mass using knowledge distillation-based deep learning in chest X-rays with external validations","authors":"Junhyeok Park,&nbsp;Nha-Young Kim,&nbsp;Hyun-Jin Bae,&nbsp;Jinhoon Jeong,&nbsp;Miso Jang,&nbsp;Sung Jin Bae,&nbsp;Jung-Min Koh,&nbsp;Seung Hun Lee,&nbsp;Joo Hee Yoon,&nbsp;Chang Hoon Lee,&nbsp;Namkug Kim","doi":"10.1007/s11657-025-01609-1","DOIUrl":"10.1007/s11657-025-01609-1","url":null,"abstract":"<div><h3>\u0000 <i>Summary</i>\u0000 </h3><p>Low bone mass (LBM), which can lead to osteoporosis, is often undetected and increases the risk of bone fractures. This study presents OsPenScreen, a deep learning model that can identify low bone mass early using standard chest X-rays (CXRs). By detecting low bone mass sooner, this tool helps prevent the disease progression to osteoporosis, potentially reducing health complications and treatment costs. OsPenScreen was validated across four external datasets and consistently performed well, showing its potential as a reliable, cost-effective solution for opportunistic early screening in CXR.</p><h3>Purpose</h3><p>Low bone mass, an often-undiagnosed precursor to osteoporosis, significantly increases fracture risk and poses a substantial public health challenge. This study aimed to develop and validate a deep learning model, OsPenScreen, for the opportunistic detection of low bone mass using routine chest X-rays (CXRs).</p><h3>Methods</h3><p>OsPenScreen, a convolutional neural network-based model, was trained on 77,812 paired CXR and dual-energy X-ray absorptiometry (DXA) datasets using knowledge distillation techniques. Validation was performed across four independent datasets (5,935 images) from diverse institutions. The model’s performance was assessed using area under the curve (AUC), accuracy, sensitivity, and specificity. Grad-CAM visualizations were employed to analyze model decision-making. Osteoporosis cases were pre-excluded by a separate model; OsPenScreen was applied only to non-osteoporotic cases.</p><h3>Results</h3><p>Our model achieved an AUC of 0.95 (95% CI: 0.94–0.97) on the external test datasets, with consistent performance across sex and age subgroups. The model demonstrated superior accuracy in detecting cases with significantly reduced bone mass and showed focused attention on weight-bearing bones in normal cases versus non-weight-bearing bones in low bone mass cases.</p><h3>Conclusion</h3><p>OsPenScreen represents a scalable and effective tool for opportunistic low bone mass screening, utilizing routine CXRs without additional healthcare burdens. Its robust performance across diverse datasets highlights its potential to enhance early detection, preventing progression to osteoporosis and reducing associated healthcare costs.</p></div>","PeriodicalId":8283,"journal":{"name":"Archives of Osteoporosis","volume":"20 1","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145249475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Living with osteoporosis: a qualitative descriptive study","authors":"Mara Tormen,&nbsp;Chiara Tedesco,&nbsp;Vicente Bernalte-Martì,&nbsp;Angela Cuoco,&nbsp;Anna Maria Carratoni,&nbsp;Gianluca Pucciarelli,&nbsp;Ercole Vellone,&nbsp;Maddalena De Maria,&nbsp;Emanuela Basilici Zannetti,&nbsp;Noemi Cittadini,&nbsp;Annalisa Pennini,&nbsp;Umberto Tarantino,&nbsp;Rosaria Alvaro","doi":"10.1007/s11657-025-01614-4","DOIUrl":"10.1007/s11657-025-01614-4","url":null,"abstract":"<div><h3>\u0000 <i>Summary</i>\u0000 </h3><p>Osteoporosis affects patients emotionally, yet this aspect is often overlooked. This study found that fear, identity changes, and communication issues shape daily life and self-care. Trust in healthcare providers fosters positive engagement. Addressing emotional experiences can enhance patient-centred osteoporosis care and support treatment adherence.</p><h3>Purpose</h3><p>To explore the emotional experiences of individuals living with osteoporosis, with the aim of improving understanding of how these emotions influence self-care behaviours and treatment adherence.</p><h3>Methods</h3><p>In this qualitative descriptive study, we conducted in-depth semi-structured interviews with 20 participants diagnosed with osteoporosis, recruited through convenience sampling from an outpatient osteoporosis clinic in central Italy. We coded the interviews deductively and analyzed data using Mayring’s qualitative content analysis framework. We used a priori thematic saturation as the criterion for stopping sampling. We reported data in accordance with the Consolidated Criteria for Reporting Qualitative Studies (COREQ) checklist.</p><h3>Results</h3><p>Participants (1 male, 19 females; age range 55–78 years) expressed a wide emotional spectrum associated with living with osteoporosis. Four overarching themes were identified: (1) emotional and psychological impact of the disease, (2) relationship with one’s identity and body, (3) interaction with healthcare professionals, and (4) managing the disease in daily life. Negative emotions, including fear, anxiety, and frustration, were frequently linked to uncertainty about treatment, insufficient communication with healthcare providers, and concerns about the disease progression. Conversely, positive emotions such as trust, hope, and satisfaction emerged when participants felt supported and engaged in their care. These emotions were associated with a stronger motivation for self-management and treatment adherence.</p><h3>Conclusion</h3><p>Living with osteoporosis involves a complex interplay of emotional responses that significantly affect patient engagement and disease management. Promoting effective communication and fostering trust between patients and healthcare providers are essential to supporting emotional well-being and enhancing adherence to osteoporosis care plans.</p></div>","PeriodicalId":8283,"journal":{"name":"Archives of Osteoporosis","volume":"20 1","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s11657-025-01614-4.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145249454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cost-utility analysis of coordinator services (FLS) in patients with femur fractures","authors":"Gyeong-Min Lee,&nbsp;Han-Sol Jang,&nbsp;Minsu Choi,&nbsp;Yonghan Cha,&nbsp;Seung Hoon Kim,&nbsp;Minah Park,&nbsp;Kwang-Soo Lee,&nbsp;Jae-Hyun Kim","doi":"10.1007/s11657-025-01610-8","DOIUrl":"10.1007/s11657-025-01610-8","url":null,"abstract":"<div><h3>\u0000 <i>Summary</i>\u0000 </h3><p>This study evaluated the cost-effectiveness of a care coordination program for hip fracture patients in Korea. The results show the program improves outcomes at a reasonable cost. These findings provide strong evidence to support national adoption of preventive care models for aging populations.</p><h3>Background</h3><p>Femur fractures in elderly patients are associated with high mortality rates and significant healthcare costs. Fracture Liaison Services (FLS) have emerged as a systematic approach to prevent secondary fractures, but their economic evaluation in the Korean healthcare context remains limited.</p><h3>Objective</h3><p>This study aimed to evaluate the cost-utility of implementing FLS coordinator services for patients with femur fractures in Korea.</p><h3>Methods</h3><p>A Markov model-based cost-utility analysis was conducted using National Health Insurance Service claims data (2013–2021) and patient survey data from Eulji University Hospital. The target population included patients aged 50 years and older with femur fractures. The analysis adopted a Limited societal perspective with a Lifetime horizon, 6-month cycle length, meaning that both direct medical costs and selected non-medical costs (e.g., caregiver and transportation expenses) were considered over the patients’ remaining Lifetime, with health states updated every 6 months in the model. A 4.5% annual discount rate was applied to both costs and quality-adjusted life years (QALYs).</p><h3>Results</h3><p>The incremental cost-effectiveness ratio (ICER) of FLS implementation was 12,057,427 KRW per QALY gained, which is below Korea’s willingness-to-pay threshold of 40 million KRW per QALY. Probabilistic sensitivity analysis showed a 92.2% probability of cost-effectiveness at the 40 million KRW threshold. The FLS program demonstrated a 41% reduction in refracture risk and a 20% reduction in mortality risk.</p><h3>Conclusions</h3><p>FLS coordinator services for femur fracture patients are cost-effective in the Korean healthcare system and should be considered for implementation to improve patient outcomes while managing healthcare expenditures efficiently.</p></div>","PeriodicalId":8283,"journal":{"name":"Archives of Osteoporosis","volume":"20 1","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145249479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Real-life effectiveness of a Fracture Liaison Service in reducing short-term mortality and second fractures after hip fracture: a five-year prospective study","authors":"David González-Quevedo,&nbsp;Manuel Bravo-Bardají,&nbsp;Carolina Rubia-Ortega,&nbsp;Adriana Sánchez-Delgado,&nbsp;Diego Moriel-Garceso,&nbsp;Juan-Manuel Sánchez-Siles,&nbsp;David García-de-Quevedo,&nbsp;Iskandar Tamimi","doi":"10.1007/s11657-025-01612-6","DOIUrl":"10.1007/s11657-025-01612-6","url":null,"abstract":"<div><h3>Summary</h3><p>We evaluated the long-term impact of a Fracture Liaison Service (FLS) in elderly hip fracture patients. FLS implementation improved one-year survival and significantly reduced the risk of secondary fractures in adherent patients. However, no significant differences in five-year mortality were observed. Structured care improves short-term outcomes and treatment adherence.</p><h3>Purpose</h3><p>Hip fractures are the most serious type of fragility fractures, as they are associated with increased short- and long-term all-cause mortality. The implementation of Fracture Liaison Service (FLS) programs has improved the management of osteoporosis-related fractures and demonstrated clinical effectiveness. This study aimed to evaluate the impact of an FLS model on survival rates, mortality reduction, and secondary fracture prevention over a five-year period.</p><h3>Methods</h3><p>We conducted a prospective cohort study on patients aged 60 years and older who sustained a hip fracture before and after FLS implementation at our centre (January 2016–December 2019). Patients were followed for five years. Mortality, complications, and secondary fractures were analysed using a multivariate Cox proportional hazards model.</p><h3>Results</h3><p>A total of 1,401 patients were included (355 pre-FLS and 1,046 post-FLS). The prescription of anti-osteoporotic drugs significantly increased after FLS implementation (77.5% vs. 12.1%; <i>p</i> &lt; 0.01), as did adherence to treatment (48.9% vs. 30.2%; <i>p</i> = 0.02). One-year mortality was lower in the post-FLS group [18.3% vs. 22.0%; adjusted HR 0.77 (0.60–0.99); <i>p</i> = 0.045]. However, five-year mortality rates showed no significant differences between groups (59.1% vs. 54.6%; <i>p</i> = 0.14). Patients adherent to osteoporosis treatment had a significantly lower risk of secondary fractures (10.8% vs. 19.1%; <i>p</i> &lt; 0.01).</p><h3>Conclusion</h3><p>Implementing an FLS protocol was associated with a significant reduction in one-year mortality and improved adherence to osteoporosis treatment, leading to a lower risk of secondary fractures. However, no significant difference was observed in overall five-year mortality.</p></div>","PeriodicalId":8283,"journal":{"name":"Archives of Osteoporosis","volume":"20 1","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145129766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of vitamin D-fortified foods on bone health and osteoporosis: a scoping review and future policies focusing on the United Arab Emirates","authors":"Sehar Iqbal,&nbsp;Maya Abuajlan,&nbsp;Amira Alktheri,&nbsp;Zoha Imtiaz Malik,&nbsp;Abdul Momin Rizwan Ahmad,&nbsp;Taima Qudah,&nbsp;Suhad Abumweis","doi":"10.1007/s11657-025-01611-7","DOIUrl":"10.1007/s11657-025-01611-7","url":null,"abstract":"<div><h3>Background</h3><p>Osteoporosis is a major public health issue characterized by reduced bone mass and increased fracture risk particularly affecting the older population.</p><h3>Objective</h3><p>This scoping review aims to summarize the existing literature focusing on the impact of vitamin D-fortified foods in reducing the risk of osteoporosis-related outcomes and improving the overall bone health.</p><h3>Methods</h3><p>Considering the study objectives, two databases, i.e., PubMed and Scopus, were selected to search for literature. A search term “vitamin D” OR “vitamin D2” OR “vitamin D3” OR “cholecalciferol” OR “ergocalciferol” AND “fortified food” OR “fortification” OR “oil fortification” OR “ghee fortification” OR “cereal fortification” OR “margarine fortification” OR “milk fortification” OR “egg fortification” AND “osteoporosis” OR “bone mineral density” OR “bone health” was applied to retrieve the available literature. Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) guidelines were followed for the methodology and results compilation.</p><h3>Results</h3><p>A total of 14 papers were included after applying the inclusion/exclusion criteria. Evidence from most of the studies (<i>n</i> = 9) indicates that regular consumption of vitamin D-fortified foods improves serum 25(OH)D levels, enhances bone mineral density, and lowers the risk of fractures. However, different factors such as age, fortification dosage, and food vehicle (type of food) appear to affect the result outcomes.</p><h3>Conclusion</h3><p>The integration of vitamin D-fortified foods into daily diets appears to be a promising nutritional intervention strategy to support bone health and prevent osteoporosis. Further research is needed for standardization of recommendations for different age groups. Moreover, for countries like the UAE, where vitamin D deficiency remains prevalent and fortification is not yet standardized, adopting an evidence-based policy could be a decisive step toward mitigating future public health and economic burdens related to osteoporosis.</p></div>","PeriodicalId":8283,"journal":{"name":"Archives of Osteoporosis","volume":"20 1","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145100664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: Trends in the prevalence of hypovitaminosis D over a 10-year period in Japan: the research on osteoarthritis/osteoporosis against disability study 2005–2015","authors":"Noriko Yoshimura,&nbsp;Toshiko Iidaka,&nbsp;Chiaki Horii,&nbsp;Gaku Tanegashima,&nbsp;Shigeyuki Muraki,&nbsp;Hiroyuki Oka,&nbsp;Hiroshi Kawaguchi,&nbsp;Toru Akune,&nbsp;Kozo Nakamura,&nbsp;Sakae Tanaka","doi":"10.1007/s11657-025-01608-2","DOIUrl":"10.1007/s11657-025-01608-2","url":null,"abstract":"","PeriodicalId":8283,"journal":{"name":"Archives of Osteoporosis","volume":"20 1","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s11657-025-01608-2.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145079042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiology of metatarsal fractures in Shropshire 2020–2023","authors":"Mark Garton,&nbsp;Jenni Rowlands,&nbsp;Richard Roach","doi":"10.1007/s11657-025-01603-7","DOIUrl":"10.1007/s11657-025-01603-7","url":null,"abstract":"<div><h3>Summary</h3><p>The epidemiology of metatarsal fractures remains poorly understood. We identified retrospectively all adults with ≥ 1 radiologically confirmed metatarsal fracture, over 3 years. Young men and women had similar fracture rates, but overall risks were significantly higher for women (RR 1.99, 95% CI 1.76–2.26), driven by age-related falls in male fracture incidence.</p><h3>Purpose</h3><p>Metatarsal fractures are clinically and economically important and may reflect trauma, insufficiency or fatigue. However, their epidemiology remains poorly understood. We evaluated radiologically confirmed metatarsal fractures identified within Shropshire over a 3-year period.</p><h3>Methods</h3><p>Radiology reports were searched for all patients aged ≥ 18 years between 2020 and 2023, using the terms ‘metatarsal’ AND ‘fracture’, to identify patients with ≥ 1 confirmed metatarsal fracture. Age at fracture, sex, fracture description and mechanism were recorded, and population fracture rates estimated, using local census data.</p><h3>Results</h3><p>A total of 1121 (758 female) individual patients aged 50.7 (18.9) years, fractured 1370 metatarsals, usually the fifth in isolation, with fewer individuals fracturing two, three or four metatarsals. Fractures were located at the metatarsal base (59%), shaft (26%), neck (12%) or head (3%); were mostly oblique, transverse or comminuted; and were usually caused by low-energy inversion injuries or falls. Fracture rates per 100,000 were 105 for women aged 18–29 years, rising to 153 and 142 in the sixth and ninth decades, with comparative male rates of 102, 40 and 31. Overall, women had more metatarsal fractures than men (RR 1.99, 95% CI 1.76–2.26), the sex difference being highest for metatarsal head fractures (RR 2.98 95% CI 1.34–6.60) and lowest for shaft fractures (RR 1.67, 95% CI 1.32–2.12).</p><h3>Conclusion</h3><p>Most metatarsal fractures are isolated low-energy injuries of the fifth metatarsal. Overall, women suffer twice as many fractures as men, driven by sustained high fracture rates in older women and a steep age-related decline among men. The underlying reasons for this pronounced sex difference are unclear and require further study.</p></div>","PeriodicalId":8283,"journal":{"name":"Archives of Osteoporosis","volume":"20 1","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145073976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}