Archives of Gastroenterology Research最新文献

Pediatric Functional Constipation in Clinical Practice: The Continuous Search for the Light at the End of the Tunnel 临床实践中的小儿功能性便秘：不断寻找隧道尽头的曙光

Archives of Gastroenterology Research Pub Date : 2023-12-22 DOI: 10.33696/gastroenterology.4.047

N. Machado, Juliana Tedesco Dias, Gabriela Nascimento Hercos, Thabata Koester Weber, Mary de Assis Carvalho

引用次数: 0

Blastocystosis and Urticaria: An Overview from a Syndemic Perspective 大疱性囊肿病和荨麻疹：从综合流行病的角度进行概述

Archives of Gastroenterology Research Pub Date : 2023-12-22 DOI: 10.33696/gastroenterology.4.046

Luis Fonte Galindo, Yamilé Aleaga Santiesteban, María Ginori Gilke, Yosiel Molina, Yisel Hernández Barrios

{"title":"Blastocystosis and Urticaria: An Overview from a Syndemic Perspective","authors":"Luis Fonte Galindo, Yamilé Aleaga Santiesteban, María Ginori Gilke, Yosiel Molina, Yisel Hernández Barrios","doi":"10.33696/gastroenterology.4.046","DOIUrl":"https://doi.org/10.33696/gastroenterology.4.046","url":null,"abstract":"Numerous studies have found an association between infection by some species of intestinal parasites and the development of urticarial lesions. In this document we have commented on the published findings that show the association between infection by Blastocystis spp. and urticaria, and on the theorizations in relation to the mechanisms that would explain it.\u0000\u0000Due to sharing risk factors and transmission ways, there is a marked geographic coincidence among intestinal parasitic infections. In fact, polyparasitism is a common phenomenon in low- and middle-income countries in Sub-Saharan Africa, Asia, Latin America, and the Caribbean where infections by protozoa and intestinal helminths are endemic. This argument, among others, suggest that the epidemiological and healthcare approach to urticaria associated with infection by Blastocystis spp. should be done from a syndemic approach that takes into account the ways in which social environments contribute to intestinal parasite infections clustering, the pathways through which those infections could interact biologically in each individual influencing the development and evolution of urticarial lesions, and the ways in which those interactions complicate diagnosis and treatment.","PeriodicalId":8277,"journal":{"name":"Archives of Gastroenterology Research","volume":"33 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138945850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advancements in Drug Delivery Systems for Natural Compounds Targeting Metabolic Disorders Associated with Inflammation 针对炎症相关代谢紊乱的天然化合物给药系统的研究进展

Archives of Gastroenterology Research Pub Date : 2023-12-02 DOI: 10.33696/gastroenterology.4.045

Roberto Sam, Sel Neal

{"title":"Advancements in Drug Delivery Systems for Natural Compounds Targeting Metabolic Disorders Associated with Inflammation","authors":"Roberto Sam, Sel Neal","doi":"10.33696/gastroenterology.4.045","DOIUrl":"https://doi.org/10.33696/gastroenterology.4.045","url":null,"abstract":"The global incidence of metabolic disorders is on the rise, posing a significant challenge to public health. With remarkable advancements in diagnostic tools and clinical procedures, our understanding of the etiology and underlying pathophysiology of these disorders has expanded considerably. Furthermore, the utilization of in vitro and in vivo experimental models, preceding clinical investigations, has catalyzed numerous breakthroughs in biomedicine, particularly in the identification and development of potential drug candidates for the management of metabolic disorders. Natural compounds isolated from various sources have garnered extensive attention as prospective drug candidates for the treatment of conditions such as diabetes, obesity, heart-related diseases, and cancer. This interest is partly attributed to their inherent antioxidant and anti-inflammatory properties. Concurrently, intensive research efforts have been directed towards enhancing the bioactivity and bioavailability of these compounds through selected drug delivery strategies. In this article, we provide valuable insights into recent advancements that shed light on the role of inflammatory-mediated responses in the initiation of metabolic disorders, with a specific focus on conditions like diabetes mellitus, obesity, heart-related diseases, cancer, and related drug delivery systems. Additionally, we explore the promising potential of natural products in managing these metabolic disorders. Furthermore, we present lists of potential biological targets suitable for high throughput screening in the drug discovery and development process. Finally, we delve into the findings gleaned from preclinical and clinical studies, setting the stage for the identification of suitable approaches in the realm of phytochemical drug delivery systems that hold promise for the treatment of metabolic disorders.","PeriodicalId":8277,"journal":{"name":"Archives of Gastroenterology Research","volume":"15 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138607119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Rare Endoscopic Finding: Gastric Diverticulum 一个罕见的内镜发现:胃憩室

Archives of Gastroenterology Research Pub Date : 2023-07-03 DOI: 10.33696/gastroenterology.4.043

Yi-Xue Zhou, Qiao Tong, Wei Liu

引用次数: 0

Exploring the Use of Point of Care Ultrasound in Screening for Non-Alcoholic Fatty Liver Disease: A Systematic Literature Review and Meta-Analysis 探索使用护理点超声筛查非酒精性脂肪性肝病:系统文献综述和荟萃分析

Archives of Gastroenterology Research Pub Date : 2023-07-03 DOI: 10.33696/gastroenterology.4.042

O. Hernández, Zoilo K Suarez, Talwinder K Nagi, M. A. Haider, Charles Vallejo, Fatima Ahson

{"title":"Exploring the Use of Point of Care Ultrasound in Screening for Non-Alcoholic Fatty Liver Disease: A Systematic Literature Review and Meta-Analysis","authors":"O. Hernández, Zoilo K Suarez, Talwinder K Nagi, M. A. Haider, Charles Vallejo, Fatima Ahson","doi":"10.33696/gastroenterology.4.042","DOIUrl":"https://doi.org/10.33696/gastroenterology.4.042","url":null,"abstract":"Non-alcoholic fatty liver disease (NAFLD) is a major cause of cirrhosis and liver failure globally. Despite its broad impact, screening recommendations for NAFLD remain varied based between gastrointestinal societies. Point of care ultrasound (POCUS) has emerged as a new form of screening and diagnosing intrabdominal pathologies including NAFLD. We aimed to estimate the effectiveness of POCUS in screening for NAFLD compared to formal ultrasound when screening by general practitioners trained in ultrasonography. Data was collected from Cochrane, PubMed, Embase, and Google Scholar using search terms related to POCUS and NAFLD screening. Observational cross-sectional studies were included in our analysis. Reviewers evaluated articles for eligibility and extracted data for analysis. The risk of bias was assessed by reviewers using a validated risk of bias assessment tool. Discrepancies between authors were resolved by a third reviewer or by consensus. Our review found 3 studies (n = 428) that met our eligibility criteria. Our review found that POCUS was 93% sensitive and 98% specific when screening for NAFLD compared to formal ultrasound. We concluded that POCUS is an acceptable method of screening for NAFLD when used by general practitioners trained in ultrasonography. Further, more robust, studies are required to validate the findings of our review and elucidate further horizons on this emerging screening method.","PeriodicalId":8277,"journal":{"name":"Archives of Gastroenterology Research","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89681870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neurofibromatosis Type 1 and Crohn’s Disease Association: Case Report 1型神经纤维瘤病与克罗恩病的关联:病例报告

Archives of Gastroenterology Research Pub Date : 2023-05-11 DOI: 10.33696/gastroenterology.4.041

A. AlShahrabally, D. Coghlan, S. Quinn

引用次数: 1

Elucidating the Role of Chemokines in Infectious Diseases and Gastric Cancer 趋化因子在感染性疾病和胃癌中的作用

Archives of Gastroenterology Research Pub Date : 2022-11-04 DOI: 10.33696/gastroenterology.3.039

Vishnu P. Tripathi, H. Ahmed, Naidia Renulos, M. K. Aneebuddin

引用次数: 1

Gastric GIST with 13 kg in Asymptomatic Patient: A Rare Case of Giant GIST and Literature Review 无症状患者13公斤的胃间质瘤:一例罕见的巨大间质瘤并文献复习

Archives of Gastroenterology Research Pub Date : 2022-11-04 DOI: 10.33696/gastroenterology.3.037

F. Silano, R. Amaral, V. Neves, Rodolfo Santana, Paulo Cézar, Galvão do Amaral

{"title":"Gastric GIST with 13 kg in Asymptomatic Patient: A Rare Case of Giant GIST and Literature Review","authors":"F. Silano, R. Amaral, V. Neves, Rodolfo Santana, Paulo Cézar, Galvão do Amaral","doi":"10.33696/gastroenterology.3.037","DOIUrl":"https://doi.org/10.33696/gastroenterology.3.037","url":null,"abstract":"Although gastrointestinal stromal tumors, GISTs, are the most common neoplasms arising from the gastrointestinal mesenchyme, they represent less than 1% of all digestive tumors [1]. Its incidence has increased in recent years, probably due to improved diagnostic methods [2]. It is currently known that GIST is the most common sarcoma [3]. It originates from interstitial cells of Cajal and depends on the transcription factor ETV-1. These are neoplasms associated with molecular alterations and some mutations: In more than 75% of cases there is the KIT mutation (CD 117) [3], 10% have mutation in platelet-derived growth factor receptor alpha (PDGFRA) and wild-type GISTs have a mutation in the SDH pathway [3]. There does not seem to be a predilection between the sexes. They affect a wide age range, but in around 75% of cases, it is more common over 50 years of age [4]. Any organ of the digestive tract can be affected by GIST, however more than 50% of cases are seen in the stomach, 25% in the small intestine and a minority in the colon, rectum, retroperitoneum, omentum, among others [5-9]. Its size can vary from millimetric lesions to the so-called giant GISTs, a definition in the literature for those with more than 10 cm in diameter [10].","PeriodicalId":8277,"journal":{"name":"Archives of Gastroenterology Research","volume":"109 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78385297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Oral Lactulose – A Safe and Effective Strategy for the Management of Constipation in Individuals with Impaired Glucose Tolerance and Diabetes 口服乳果糖-一种安全有效的治疗糖耐量受损和糖尿病患者便秘的策略

Archives of Gastroenterology Research Pub Date : 2022-11-04 DOI: 10.33696/gastroenterology.3.036

V. Faerber, K. Kuhn, E. Svehlikova, A. Kuchinka-Koch, T. Pieber

引用次数: 0

Intraductal Tubular Adenoma: A Case Report and Diagnostic Algorithm for Intraductal Pancreatic Lesions 导管内管状腺瘤:1例导管内胰腺病变的诊断方法

Archives of Gastroenterology Research Pub Date : 2022-11-04 DOI: 10.33696/gastroenterology.3.040

Shiv K. Desai, C. Schammel, D. Schammel, A. Devane, D. Steven, Trocha

引用次数: 0