发布求助
文献互助 智能选刊 最新文献

Archiv fur Geschwulstforschung最新文献

筛选
英文 中文
Organization of cancer care in Belgium. 比利时癌症护理组织。
Archiv fur Geschwulstforschung Pub Date : 1989-01-01
J Frühling
{"title":"Organization of cancer care in Belgium.","authors":"J Frühling","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":8274,"journal":{"name":"Archiv fur Geschwulstforschung","volume":"59 3","pages":"219-20"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13896386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Organization of cancer care in France. 法国癌症护理组织。
Archiv fur Geschwulstforschung Pub Date : 1989-01-01
C Lagarde
{"title":"Organization of cancer care in France.","authors":"C Lagarde","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":8274,"journal":{"name":"Archiv fur Geschwulstforschung","volume":"59 4","pages":"299-300"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13941888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Therapy of cancer pain--a comprehensive therapy concept]. 【癌痛的治疗——综合治疗理念】。
Archiv fur Geschwulstforschung Pub Date : 1989-01-01
G Tontschev
{"title":"[Therapy of cancer pain--a comprehensive therapy concept].","authors":"G Tontschev","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A comprehensive conception for cancer pain treatment is presented. The medical analgesic drug therapy representing the main point of this conception is applied as a three steps analgesic ladder as recommend by the WHO. This kind of therapy enables an individual adaptation resp. increase of the analgesic intensity by the use of non narcotic analgetics, weak and strong opioids as well as adjuvant drugs. Besides the explanation of the principles of its application and some detailed instructions for the dosage of several drugs, possible side effects and interactions are mentioned as well as some examples for its clinical application are quoted. A further increase of the analgesic intensity is reached by the local intraspinal application of morphine. For this purpose epidural and intrathecal long-term catheters are used. Also in these cases dosage, side effects and complications are mentioned and the possibilities and advantages of the continuous analgesia with implantable systems (pain ports) and external portable or implantable pumps are discussed. Furthermore the role of the neurolytic blocks, neurosurgical treatment and radiation therapy within this conception is mentioned.</p>","PeriodicalId":8274,"journal":{"name":"Archiv fur Geschwulstforschung","volume":"59 1","pages":"53-63"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13614421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Different ultrastructural feature of keratinocytes in human malignant melanomas. 人恶性黑色素瘤中角质形成细胞超微结构的差异。
Archiv fur Geschwulstforschung Pub Date : 1989-01-01
H Klug, H Winter, W Lehnert
{"title":"Different ultrastructural feature of keratinocytes in human malignant melanomas.","authors":"H Klug,&nbsp;H Winter,&nbsp;W Lehnert","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The ultrastructural feature of keratinocytes was investigated in human superficially spreading melanomas of type B. The tumor cells of these melanomas are characterized by spheroidal melanosomes and containing pheomelanins. Contrary to type A melanomas the keratinocytes show no striking transformation reaction neither in the nucleus nor in the cytoplasm although this part of the cell mostly contains abundant melanin granules surrounding the nucleus. Whether there exists a relation to the clinical course still has to be clarified.</p>","PeriodicalId":8274,"journal":{"name":"Archiv fur Geschwulstforschung","volume":"59 2","pages":"107-12"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13617211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Multicenter pilot studies on the determination of steroid hormone receptors]. [类固醇激素受体测定的多中心试点研究]。
Archiv fur Geschwulstforschung Pub Date : 1989-01-01
M Görlich, B Lampe
{"title":"[Multicenter pilot studies on the determination of steroid hormone receptors].","authors":"M Görlich,&nbsp;B Lampe","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Corresponding the international tendency two trials have been performed in GDR to compare results of hormone receptor determinations with prepared probes by several laboratories. As probes we used lyophilized calf uterus. Methods applied for receptor determinations based on dextran charcoal technique, but allowed modalities developed in the various laboratories. In consequence of extensive scattering of results got during the first trial an additional investigation basing on a standard procedure was performed in the second trial. Using this standard procedure better corresponding results could be found in comparison to investigations following the laboratory modalities. Consequently application of a standardized technique in all laboratories should be demanded. Final aim of these efforts is to obtain a reliable semiquantitative classification of low, medium and high receptor contents in the tissue probes investigated.</p>","PeriodicalId":8274,"journal":{"name":"Archiv fur Geschwulstforschung","volume":"59 6","pages":"441-8"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13828758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Drugs from the classes of tricyclic antidepressives and antiepileptics, nitrosatable under simulated human gastric conditions]. [三环类抗抑郁药和抗癫痫药，在模拟人体胃条件下具有亚硝基性]。
Archiv fur Geschwulstforschung Pub Date : 1989-01-01
D Ziebarth, T Schramm, A Töppel
{"title":"[Drugs from the classes of tricyclic antidepressives and antiepileptics, nitrosatable under simulated human gastric conditions].","authors":"D Ziebarth,&nbsp;T Schramm,&nbsp;A Töppel","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The nitrosatability of Pryleugan (imipramine), Herphonal (trimipramine), and Finlepsin (carbamazepine) was investigated under simulated human gastric conditions using a colorimetric measuring method. All of them proved to be nitrosatable even at very low nitrite concentrations. In the presence of ascorbic acid, the formation of N-nitroso compounds under model conditions was inhibited markedly. N-nitroso-dihydrodibenzazepine and N-nitroso-dibenzazepine could be identified by thin layer chromatography as main products. The biological effects of these N-nitroso compounds are not known up to now.</p>","PeriodicalId":8274,"journal":{"name":"Archiv fur Geschwulstforschung","volume":"59 4","pages":"257-63"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13941884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Organization of cancer care in Austria. 奥地利癌症护理组织。
Archiv fur Geschwulstforschung Pub Date : 1989-01-01
H Wrba
{"title":"Organization of cancer care in Austria.","authors":"H Wrba","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":8274,"journal":{"name":"Archiv fur Geschwulstforschung","volume":"59 5","pages":"375-6"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13732823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Acute and subacute toxicity of antineoplastic Pt(II) and Pt(IV) coordination compounds in laboratory rodents]. [抗肿瘤铂(II)和铂(IV)配位化合物对实验室啮齿动物的急性和亚急性毒性]。
Archiv fur Geschwulstforschung Pub Date : 1989-01-01
A Härtl, J Güttner, U Horn, F Jelinek, U Stöckel, H P Schröer, H Hoffmann
{"title":"[Acute and subacute toxicity of antineoplastic Pt(II) and Pt(IV) coordination compounds in laboratory rodents].","authors":"A Härtl,&nbsp;J Güttner,&nbsp;U Horn,&nbsp;F Jelinek,&nbsp;U Stöckel,&nbsp;H P Schröer,&nbsp;H Hoffmann","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>After single i.v. administration of cis-diammine-platinum(II)-lactate cis-diammine-platinum(II)-lactate, L cis-diammine-platinum(II)-dilactate trans-dihydroxy-cis-dichlorodiammine-platinum(IV), the LD50 values have been calculated to range between 80 and 130 mg/kg in mice, and between 22 and 45 mg/kg in rats. The LD50 of cis-DDP amounted to 17 mg/kg and 6.6 mg/kg, respectively. Likewise, the compounds have been found to be about 3 to 5 times less toxic than the standard cis-DDP when administered daily for 5 consecutive days. Since the kidneys, the bone marrow, the lymphatic tissue and the intestinal tract have been proved to be the main target organs, the profile of the toxic action of the Pt(II)-complexes seems to be similar to that of cis-DDP. Additionally, the Pt(IV) compound has been found to be toxic to the pancreas, the liver and the salivary glands. With regard to the antineoplastic activity the more soluble lactates of cis-DDP showed a smaller therapeutic index compared to cis-DDP.</p>","PeriodicalId":8274,"journal":{"name":"Archiv fur Geschwulstforschung","volume":"59 4","pages":"239-44"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13783627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The genotoxic effect of epichlorohydrin and epoxy resins]. [环氧氯丙烷和环氧树脂的遗传毒性效应]。
Archiv fur Geschwulstforschung Pub Date : 1989-01-01
G Bittersohl, J Bittersohl
{"title":"[The genotoxic effect of epichlorohydrin and epoxy resins].","authors":"G Bittersohl,&nbsp;J Bittersohl","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The aim of this study is the interpretation of the available bibliography concerning the present information about the mutagenic and carcinogenic effects of epichlorohydrin and epoxy resins. An intervention study on 141 exposed workers shows the necessity of an investigation about the well-timed perception of the carcinogenic risk. The development of an electrophoretic method is recommended to detect the alkylated hemoglobin by way of the biological monitoring.</p>","PeriodicalId":8274,"journal":{"name":"Archiv fur Geschwulstforschung","volume":"59 3","pages":"171-5"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13808604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Three new applicators for hyperthermia. 三种新的热疗应用器。
Archiv fur Geschwulstforschung Pub Date : 1989-01-01
P Gabriele, R Orecchia, V Tseroni, A Melano, C Fillini, R Ragona, L Bolla, G Ogno
{"title":"Three new applicators for hyperthermia.","authors":"P Gabriele,&nbsp;R Orecchia,&nbsp;V Tseroni,&nbsp;A Melano,&nbsp;C Fillini,&nbsp;R Ragona,&nbsp;L Bolla,&nbsp;G Ogno","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A computerized system with automatic treatment parameters control for radiological hyperthermia, called Sapic SV03, is presented. The system has been planned and built by the \"Sezione Avionica ed Equipaggiamenti\" of the Aeritalia in cooperation with the Radiotherapy Department of the University of Turin. The device is supplied with a multifrequency generator system (915, 433, 2-30 MHz) connected with many kinds of applicators, with a fiber optic system for temperature control and a previsional thermometry system. In this paper the authors presented three new applicators. The first one is a concave parallel microstrip applicator at 433 MHz, with a size 16 x 9 cm; the heating pattern is homogenous until 4 cm of depth. This antenna can be used for the treatment of chest wall recurrences of breast cancer. The second is a 27 MHz inductive ring and the third applicator is a pyramidal antenna (\"TEM line\") that operates at a frequency around 27 MHz.</p>","PeriodicalId":8274,"journal":{"name":"Archiv fur Geschwulstforschung","volume":"59 4","pages":"271-5"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13941886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信