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Archiv fur Geschwulstforschung最新文献

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[Temperature, pH value, acid load and filterability of normal human erythrocytes: in vitro studies, possible significance for hyperthermic tumor therapy. Comments on the paper by W.K. Barnikol]. 正常人红细胞的温度、pH值、酸负荷和滤过性:体外研究，可能对高热肿瘤治疗有重要意义。W.K. Barnikol对论文的评论。
Archiv fur Geschwulstforschung Pub Date : 1989-01-01
M von Ardenne, P G Reitnauer
{"title":"[Temperature, pH value, acid load and filterability of normal human erythrocytes: in vitro studies, possible significance for hyperthermic tumor therapy. Comments on the paper by W.K. Barnikol].","authors":"M von Ardenne, P G Reitnauer","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":8274,"journal":{"name":"Archiv fur Geschwulstforschung","volume":"59 5","pages":"383-4"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13733473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gas chromatographic-mass spectrometric investigation of four commercial pristane (2.6.10.14-tetramethylpentadecane) preparations used for plasmacytoma induction in BALB/c mice. 四种商用戊烷(2.6.10.14-四甲基戊烷)用于诱导BALB/c小鼠浆细胞瘤的气相色谱-质谱研究。
Archiv fur Geschwulstforschung Pub Date : 1989-01-01
S Janz, T Birkenfeld, R Herzschuh, H Storch
{"title":"Gas chromatographic-mass spectrometric investigation of four commercial pristane (2.6.10.14-tetramethylpentadecane) preparations used for plasmacytoma induction in BALB/c mice.","authors":"S Janz,&nbsp;T Birkenfeld,&nbsp;R Herzschuh,&nbsp;H Storch","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The most widely studied model of plasmacytomagenesis is the induction of plasmacytomas by intraperitoneal injections of pure alkanes such as pristane (2.6.10.14-tetramethylpentadecane). The presence of small amounts of genotoxic contaminants, that could contribute to the complex oncogenic process, in commercial pristane preparations has not been completely ruled out. Therefore, we conducted a chemical analysis of different pristane preparations applying a combined GC/MS technique, but were not capable of identifying any obvious or putative genotoxic/cancerogenic contaminants.</p>","PeriodicalId":8274,"journal":{"name":"Archiv fur Geschwulstforschung","volume":"59 6","pages":"415-22"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13738323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The importance of bronchologic procedures in the diagnosis of bronchial carcinoma]. 【支气管检查在支气管癌诊断中的重要性】。
Archiv fur Geschwulstforschung Pub Date : 1989-01-01
B Wiesner
{"title":"[The importance of bronchologic procedures in the diagnosis of bronchial carcinoma].","authors":"B Wiesner","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>For an adequate therapy decision it is necessary to diagnose tumour suspicious findings always as immediately as possible. Bronchological methods and bioptic measurements take the first place in the diagnosis of bronchial carcinoma. With these methods an exact localization of tumour growth in the bronchial system, collection of specimens from the tumour for histological and cytological examinations, and the examination of the bronchial system with regard to the local operability are possible. The bronchological technique using rigid and flexible instruments allows an exact inspection of all bronchial parts down to the bronchi of the 5th generation. With supplementary equipment peripheral tumours are also attainable. The value of bronchological and bioptic methods are critically represented.</p>","PeriodicalId":8274,"journal":{"name":"Archiv fur Geschwulstforschung","volume":"59 6","pages":"449-54"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13829365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Organization of cancer control in the USSR. 苏联的癌症控制组织。
Archiv fur Geschwulstforschung Pub Date : 1989-01-01
N N Trapeznikov, N A Tikhonova, L E Komarova
{"title":"Organization of cancer control in the USSR.","authors":"N N Trapeznikov,&nbsp;N A Tikhonova,&nbsp;L E Komarova","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":8274,"journal":{"name":"Archiv fur Geschwulstforschung","volume":"59 3","pages":"221-3"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13896387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comprehensive cancer centres in The Netherlands. 荷兰的综合癌症中心。
Archiv fur Geschwulstforschung Pub Date : 1989-01-01
F J Cleton
{"title":"Comprehensive cancer centres in The Netherlands.","authors":"F J Cleton","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":8274,"journal":{"name":"Archiv fur Geschwulstforschung","volume":"59 1","pages":"65-8"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14058627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Immunostimulants--therapeutic aspects]. (免疫刺激剂,治疗方面)。
Archiv fur Geschwulstforschung Pub Date : 1989-01-01
W Diezel, H D Volk, V Daniel, S Gruner, N Sönnichsen
{"title":"[Immunostimulants--therapeutic aspects].","authors":"W Diezel,&nbsp;H D Volk,&nbsp;V Daniel,&nbsp;S Gruner,&nbsp;N Sönnichsen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A survey is given about the so far known mode of action and the therapeutic application of the following agents with immunostimulatory effects: Interleukin-2, Interferon-gamma, Tumor necrosis factor, Thymosin alpha 1, Thymopentin, Splenopentin, Thymulin, Thymostimulin, Muramyl dipeptide, Bestatin, Tuftsin and Levamisole. The treatment of patients suffering from immunodeficiency disorders and cancer with such agents seems to be possible in the near future.</p>","PeriodicalId":8274,"journal":{"name":"Archiv fur Geschwulstforschung","volume":"59 1","pages":"45-51"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13639924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neuroimmunitary profile estimation in cerebrospinal fluid and its importance in childhood acute lymphoblastic leukaemia. 儿童急性淋巴细胞白血病脑脊液的神经免疫特征评估及其重要性。
Archiv fur Geschwulstforschung Pub Date : 1989-01-01
S M Crivii, S Neamtu, G Bocsan
{"title":"Neuroimmunitary profile estimation in cerebrospinal fluid and its importance in childhood acute lymphoblastic leukaemia.","authors":"S M Crivii,&nbsp;S Neamtu,&nbsp;G Bocsan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Immunoglobulin G (IgG) and albumin (Alb.) were measured in the cerebrospinal fluid (CSF) of 14 children with acute lymphoblastic leukaemia (ALL), with and without leukaemic infiltration of the central nervous system (CNS). The following indexes: (formula; see text) were calculated and used to express a protein profile of the CSF. This profile was found to be inflammatory-like in 10 children (71%) and normal in 4 (29%). The first two indexes, that reflect a local synthesis of IgG correlated significantly (r = 0.823; p less than 0.001). The follow-up made in five children showed a relationship between clinical course and local IgG synthesis.</p>","PeriodicalId":8274,"journal":{"name":"Archiv fur Geschwulstforschung","volume":"59 3","pages":"199-204"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13896383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Non-random karyotypic changes in Djungarian hamster tumors induced by 3-methylcholanthrene. 3-甲基胆蒽诱导的保加利亚仓鼠肿瘤的非随机核型变化。
Archiv fur Geschwulstforschung Pub Date : 1989-01-01
O I Sokova, H E Pogosianz
{"title":"Non-random karyotypic changes in Djungarian hamster tumors induced by 3-methylcholanthrene.","authors":"O I Sokova,&nbsp;H E Pogosianz","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The karyotypes of 30 tumors (sarcomas and adenocarcinomas) induced with methylcholanthrene in Djungarian hamsters (Phodopus sungorus campbelli) have been investigated. In 23 tumors structural changes of the short arm of X-chromosome (Xp+ or Xp = type) were revealed. Non-random rearrangements of 3p, 7q and 8q were also observed. Other structural or numerical changes of the karyotype were accidential. For majority of tumors the presence of chromosome markers with long homogeneously staining regions or double minutes, structures are known as cytological manifestation of gene amplification, was typical. Induced tumors of the Djungarian hamster might serve as an interesting tool for studies of relationship of somatic cell genetic changes to different aspects of chemical carcinogenesis.</p>","PeriodicalId":8274,"journal":{"name":"Archiv fur Geschwulstforschung","volume":"59 6","pages":"399-406"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13738320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Nephrotoxicity and myelotoxicity of antineoplastic Pt(II) and Pt(IV) coordination compounds in rats]. [抗肿瘤Pt(II)和Pt(IV)配位化合物对大鼠的肾毒性和骨髓毒性]。
Archiv fur Geschwulstforschung Pub Date : 1989-01-01
U Horn, A Härtl, G Neuhaus, U Stöckel, H P Schröer, H Hoffmann
{"title":"[Nephrotoxicity and myelotoxicity of antineoplastic Pt(II) and Pt(IV) coordination compounds in rats].","authors":"U Horn,&nbsp;A Härtl,&nbsp;G Neuhaus,&nbsp;U Stöckel,&nbsp;H P Schröer,&nbsp;H Hoffmann","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In comparison with cis-DDP four new platinum (II) and platinum (IV) complexes were evaluated for their acute nephrotoxic and myelotoxic potency in male rats following i.v. administration of maximum tolerated doses on 5 consecutive days. Parameters for nephrotoxicity determined on day 6, 13 and 22 after the first administration of the drugs included blood, urea nitrogen, serum creatinine, urine volume, urinary glucose and tubule cell excretion. Parameters for myelotoxicity determined on the same days included leucocytes, platelets, hemoglobin and hematocrit. Cis-DDP was found to be the most nephrotoxic compound. The myelotoxicity of the new platinum complexes appeared to be similar to that of cis-DDP with exception of trans-ODDP.</p>","PeriodicalId":8274,"journal":{"name":"Archiv fur Geschwulstforschung","volume":"59 4","pages":"245-50"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13940657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Organization of cancer care in the German Democratic Republic. 德意志民主共和国癌症护理组织。
Archiv fur Geschwulstforschung Pub Date : 1989-01-01
S Tanneberger
{"title":"Organization of cancer care in the German Democratic Republic.","authors":"S Tanneberger","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":8274,"journal":{"name":"Archiv fur Geschwulstforschung","volume":"59 1","pages":"69-72"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14058628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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