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News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society最新文献

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Language in the right cerebral hemisphere: contributions from reading studies. 右脑半球的语言:阅读研究的贡献。
News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society Pub Date : 2003-12-01 DOI: 10.1152/nips.01454.2003
Kirsten I Taylor, Marianne Regard
{"title":"Language in the right cerebral hemisphere: contributions from reading studies.","authors":"Kirsten I Taylor,&nbsp;Marianne Regard","doi":"10.1152/nips.01454.2003","DOIUrl":"https://doi.org/10.1152/nips.01454.2003","url":null,"abstract":"<p><p>Evidence for a right hemispheric involvement in language processing, in particular at the level of word meaning, has emerged within the last half century. Hemispheric functional specializations are dynamic; right hemispheric language participation significantly increases under certain conditions, such as during an epileptic seizure and during recovery from stroke. Interhemispheric connections via the corpus callosum critically mediate these and other higher cortical functions.</p>","PeriodicalId":82140,"journal":{"name":"News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society","volume":"18 ","pages":"257-61"},"PeriodicalIF":0.0,"publicationDate":"2003-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1152/nips.01454.2003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24072163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 44
The vanilloid receptor family of calcium-permeable channels: molecular integrators of microenvironmental stimuli. 钙渗透通道的香草受体家族:微环境刺激的分子整合者。
News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society Pub Date : 2003-12-01 DOI: 10.1152/nips.01468.2003
Roger G O'Neil, Rachel C Brown
{"title":"The vanilloid receptor family of calcium-permeable channels: molecular integrators of microenvironmental stimuli.","authors":"Roger G O'Neil,&nbsp;Rachel C Brown","doi":"10.1152/nips.01468.2003","DOIUrl":"https://doi.org/10.1152/nips.01468.2003","url":null,"abstract":"<p><p>The TRPV subfamily of calcium-permeable channels is widely distributed in sensory and nonsensory cells from nematodes to mammals. These channels can be variably activated by a diverse range of stimuli (osmotic/mechanical stress, noxious chemicals and heat, endogenous mediators) that often converge on the same channel. Evidence is presented that TRPV channels function as novel \"molecular integrators\" of diverse microenvironmental stimuli.</p>","PeriodicalId":82140,"journal":{"name":"News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society","volume":"18 ","pages":"226-31"},"PeriodicalIF":0.0,"publicationDate":"2003-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1152/nips.01468.2003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24072781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 61
Allosteric proteins: lessons to be learned from the hemoglobin intermediates. 变构蛋白:从血红蛋白中间体中吸取的教训。
News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society Pub Date : 2003-12-01 DOI: 10.1152/nips.01451.2003
Michele Perrella, Rosaria Russo
{"title":"Allosteric proteins: lessons to be learned from the hemoglobin intermediates.","authors":"Michele Perrella,&nbsp;Rosaria Russo","doi":"10.1152/nips.01451.2003","DOIUrl":"https://doi.org/10.1152/nips.01451.2003","url":null,"abstract":"<p><p>Allosteric proteins, such as hemoglobin, are assemblies of functional units, which undergo quaternary structural transitions in response to concentration changes of a specific ligand. Functional properties of hemoglobin ligation intermediates indicate that the tertiary structural changes induced by the ligand do not promote an equilibrium of quaternary structures.</p>","PeriodicalId":82140,"journal":{"name":"News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society","volume":"18 ","pages":"232-6"},"PeriodicalIF":0.0,"publicationDate":"2003-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1152/nips.01451.2003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24072782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Matching the heart to heat-induced circulatory load: heat-acclimatory responses. 使心脏适应热诱导的循环负荷:热适应反应。
News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society Pub Date : 2003-12-01 DOI: 10.1152/nips.01453.2003
Michal Horowitz
{"title":"Matching the heart to heat-induced circulatory load: heat-acclimatory responses.","authors":"Michal Horowitz","doi":"10.1152/nips.01453.2003","DOIUrl":"https://doi.org/10.1152/nips.01453.2003","url":null,"abstract":"<p><p>Heat acclimation enhances cardiac efficiency by increasing stroke volume and decreasing heart rate. These adaptations involve biochemical changes in the contractile apparatus, switched on by altered expression of genes coding contractile and calcium-regulatory proteins and partially mediated by persistent low thyroxine. Heat acclimation also produces cross-tolerance to oxygen deprivation, thus reinforcing cardiac adaptation to oxygen demand/supply mismatching via energy-sparing pathways.</p>","PeriodicalId":82140,"journal":{"name":"News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society","volume":"18 ","pages":"215-21"},"PeriodicalIF":0.0,"publicationDate":"2003-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1152/nips.01453.2003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24072778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 50
Flt3 ligand: role in control of hematopoietic and immune functions of the bone marrow. Flt3配体:在骨髓造血和免疫功能控制中的作用。
News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society Pub Date : 2003-12-01 DOI: 10.1152/nips.01452.2003
Aleksandra Wodnar-Filipowicz
{"title":"Flt3 ligand: role in control of hematopoietic and immune functions of the bone marrow.","authors":"Aleksandra Wodnar-Filipowicz","doi":"10.1152/nips.01452.2003","DOIUrl":"https://doi.org/10.1152/nips.01452.2003","url":null,"abstract":"<p><p>The concerted action of cytokines secreted locally in the bone marrow controls the maintenance, expansion, and differentiation of hematopoietic stem cells (HSCs), whereas aberrant cytokine signaling contributes to leukemic transformation. Potent effects of flt3 ligand on HSCs and the development of the immune system have generated much interest in the clinical application of this cytokine in stem cell transplantation and cancer immunotherapy.</p>","PeriodicalId":82140,"journal":{"name":"News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society","volume":"18 ","pages":"247-51"},"PeriodicalIF":0.0,"publicationDate":"2003-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1152/nips.01452.2003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24072161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 54
Purinergic signaling along the renal tubule: the current state of play. 沿肾小管的嘌呤能信号:当前的发挥状态。
News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society Pub Date : 2003-12-01 DOI: 10.1152/nips.01436.2003
Robert J Unwin, Matthew A Bailey, Geoffrey Burnstock
{"title":"Purinergic signaling along the renal tubule: the current state of play.","authors":"Robert J Unwin,&nbsp;Matthew A Bailey,&nbsp;Geoffrey Burnstock","doi":"10.1152/nips.01436.2003","DOIUrl":"https://doi.org/10.1152/nips.01436.2003","url":null,"abstract":"<p><p>ATP-sensitive P2 receptors have been described in all mammalian nephron segments. A reductionist approach has demonstrated purinergic control of renal transporters in cell lines and heterologous expression systems. This brief update focuses on what is known of these receptors in native nephron segments (excluding the glomerulus) and outlines recent advances and possible future directions.</p>","PeriodicalId":82140,"journal":{"name":"News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society","volume":"18 ","pages":"237-41"},"PeriodicalIF":0.0,"publicationDate":"2003-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1152/nips.01436.2003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24072783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 107
Mitochondrial regulation of intracellular Ca2+ signaling: more than just simple Ca2+ buffers. 细胞内Ca2+信号的线粒体调节:不仅仅是简单的Ca2+缓冲。
News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society Pub Date : 2003-12-01 DOI: 10.1152/nips.01458.2003
Anant B Parekh
{"title":"Mitochondrial regulation of intracellular Ca2+ signaling: more than just simple Ca2+ buffers.","authors":"Anant B Parekh","doi":"10.1152/nips.01458.2003","DOIUrl":"https://doi.org/10.1152/nips.01458.2003","url":null,"abstract":"<p><p>Mitochondrial Ca(2+) uptake shapes the profile of intracellular Ca(2+) signals, both spatially and temporally. In addition, such uptake controls the gating of Ca(2+) release and store-operated Ca(2+) entry channels, partitions cells into subcellular Ca(2+) hotspots, and can result in the release of diffusible signals into the cytosol that subsequently regulate protein function.</p>","PeriodicalId":82140,"journal":{"name":"News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society","volume":"18 ","pages":"252-6"},"PeriodicalIF":0.0,"publicationDate":"2003-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1152/nips.01458.2003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24072162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 92
Ghrelin: a novel player in the gut-brain regulation of growth hormone and energy balance. 胃饥饿素:肠-脑调节生长激素和能量平衡的新角色。
News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society Pub Date : 2003-12-01 DOI: 10.1152/nips.01460.2003
David H St-Pierre, Lixin Wang, Yvette Taché
{"title":"Ghrelin: a novel player in the gut-brain regulation of growth hormone and energy balance.","authors":"David H St-Pierre,&nbsp;Lixin Wang,&nbsp;Yvette Taché","doi":"10.1152/nips.01460.2003","DOIUrl":"https://doi.org/10.1152/nips.01460.2003","url":null,"abstract":"<p><p>Ghrelin is a newly discovered peptide hormone produced by the stomach that displays potent growth hormone-releasing activity and a stimulatory effect on food intake and digestive function while reducing energy expenditure. The isolation of ghrelin has led to new insights into how this gastric hormone links the endocrine control of nutritional homeostasis with growth hormone secretion and gastrointestinal motility through gut-brain interactions.</p>","PeriodicalId":82140,"journal":{"name":"News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society","volume":"18 ","pages":"242-6"},"PeriodicalIF":0.0,"publicationDate":"2003-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1152/nips.01460.2003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24072160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 78
Understanding trabecular meshwork physiology: a key to the control of intraocular pressure? 了解小梁网生理学:控制眼压的关键?
News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society Pub Date : 2003-10-01 DOI: 10.1152/nips.01443.2003
Artur Llobet, Xavier Gasull, Arcadi Gual
{"title":"Understanding trabecular meshwork physiology: a key to the control of intraocular pressure?","authors":"Artur Llobet,&nbsp;Xavier Gasull,&nbsp;Arcadi Gual","doi":"10.1152/nips.01443.2003","DOIUrl":"https://doi.org/10.1152/nips.01443.2003","url":null,"abstract":"","PeriodicalId":82140,"journal":{"name":"News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society","volume":" ","pages":"205-9"},"PeriodicalIF":0.0,"publicationDate":"2003-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1152/nips.01443.2003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40815970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 137
The engine of ABC proteins. ABC蛋白的引擎。
News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society Pub Date : 2003-10-01 DOI: 10.1152/nips.01445.2003
Guillermo A Altenberg
{"title":"The engine of ABC proteins.","authors":"Guillermo A Altenberg","doi":"10.1152/nips.01445.2003","DOIUrl":"https://doi.org/10.1152/nips.01445.2003","url":null,"abstract":"","PeriodicalId":82140,"journal":{"name":"News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society","volume":" ","pages":"191-5"},"PeriodicalIF":0.0,"publicationDate":"2003-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1152/nips.01445.2003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40815967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 21
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