Annali italiani di chirurgia最新文献

{"title":"Diode Laser Surgery for the Disinclusion of Palatally Impacted Canines: A Case Report.","authors":"Martina Horodynski, Adriana Assunta De Stefano, Francesca Crocamo, Alessandra Impellizzeri, Umberto Romeo, Gabriella Galluccio","doi":"10.62713/aic.3592","DOIUrl":"https://doi.org/10.62713/aic.3592","url":null,"abstract":"<p><strong>Aim: </strong>Mandibular third molars are the most frequently impacted teeth, followed by maxillary canines. Between one and three percent of the general population is affected by permanent maxillary canine impaction; in males, this condition is less common than in females. This case report evaluates the spontaneous eruption of palatally impacted canines following diode laser exposure.</p><p><strong>Case presentation: </strong>A 15-year-old female referred to our observation to improve her smile. At the first visit, the absence of upper left permanent canines and the persistence of upper right primary canines were detected. Meticulous surgical exposure with a diode laser was planned based on the cone beam computed tomography (CBCT). The wound was covered with a periodontal pack, and the traction of the teeth in the dental arch was achieved without the need for orthodontic devices. The canines' eruption was tracked at 1, 8 and 16 weeks following surgery, using an intraoral scanner (Medit i700, Medit Corp., Seoul, South Korea) and photos.</p><p><strong>Results: </strong>Both canines completely erupted 16 weeks after surgery, so brackets were placed on them, and self-ligating multibrackets were used to bandage the upper arch.</p><p><strong>Conclusions: </strong>Laser surgery for impacted canines is an excellent conservative option for their exposure; compared to standard surgery, it offers several advantages, including faster eruption, no need for sutures, and no bleeding during or after the operation.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 2","pages":"143-151"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143432357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating the Factors Affecting Plaque Formation after Peri-Implantitis and Incorporating Crucial Factors to Develop a Predictive Model: A Retrospective Cohort Study.","authors":"Yingjie Xu, Yue Feng, Zhengting Tang, Dezhao Yang, Fanwen Meng","doi":"10.62713/aic.3881","DOIUrl":"https://doi.org/10.62713/aic.3881","url":null,"abstract":"<p><strong>Aim: </strong>This study aims to explore the factors impacting implant plaque re-formation after implant polishing surgery for peri-implantitis and to establish a predictive model using crucial factors, thereby providing an evidence-based reference for managing this condition.</p><p><strong>Methods: </strong>This retrospective study analyzed clinical data from 203 patients who underwent implant polishing and shaping procedures in Suzhou Stomatological Hospital between November 2018 and October 2023. Study subjects were divided into a training set (n = 142) and a validation set (n = 61) in a 7:3 ratio. Univariate and multivariate logistic regression analyses were used to assess the risk factors associated with biofilm formation after implant polishing and shaping surgery. Incorporating significantly linked factors, a risk prediction model was developed. Furthermore, the predictive model was evaluated in the training and validation sets using the Hosmer-Lemeshow (H-L) goodness-of-fit test, Receiver Operating Characteristic (ROC) curve, calibration curve, and decision curve analysis (DCA) to determine its discriminatory capability, goodness-of-fit, and predictive utility.</p><p><strong>Results: </strong>Multivariate logistic regression analysis revealed that calculus [Odds Ratio (OR) = 3.071, 95% Confidence Interval (CI): 1.104-8.541, p = 0.032], difficult-to-clean implant location (OR = 5.807, 95% CI: 1.895-17.798, p = 0.002), external connection implant abutment (OR = 4.378, 95% CI: 1.440-13.308, p = 0.009), and implant diameter (OR = 4.511, 95% CI: 2.141-9.504, p < 0.001) were significant factors affecting biofilm formation after implant polishing and shaping surgery. A regression equation (predictive model) was constructed, incorporating the four crucial risk factors and regression coefficients. ROC curve analysis demonstrated that the area under curve (AUC) of the predictive model was 0.9143 (95% CI: 0.8221-0.9782) in the training set and 0.8095 (95% CI: 0.7342-0.9051) in the validation set. Furthermore, the Hosmer-Lemeshow test indicated a good fit of the established model, with no statistically significant difference between predicted and observed values in both the training set (p = 0.399) and the validation set (p = 0.317). Additionally, DCA demonstrated that the predictive model provides a significant net benefit.</p><p><strong>Conclusions: </strong>The predictive model developed using the key risk factors contributing to plaque formation after implant polishing exhibits strong predictive capability, which provides an evidence-based reference in preventing and managing postoperative plaque formation.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 3","pages":"391-399"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143639429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Significance of MRI-Based Measurements of Tibial Plateau Widening Width and Joint Fluid Volume During Anterior Cruciate Ligament Injuries Among Patients With Tibial Plateau Fractures.","authors":"Qinglin Shi, Gang Yang, Juan Du","doi":"10.62713/aic.3899","DOIUrl":"https://doi.org/10.62713/aic.3899","url":null,"abstract":"<p><strong>Aim: </strong>This study aimed to explore the diagnostic value of magnetic resonance imaging (MRI)-based tibial plateau widening width (TPW) and joint effusion volume during anterior cruciate ligament (ACL) injuries among patients with tibial plateau fractures.</p><p><strong>Methods: </strong>This retrospective study collected clinical data from 100 patients with tibial plateau fractures admitted between February 2022 and February 2024. The findings from arthroscopy or surgical intervention served used as the \"gold standard\". Based on the ACL injury, patients were divided into the injury group (62 cases) and the control group (38 cases). General data were compared between the two groups. Furthermore, TPW and joint effusion were assessed using MRI outcomes, and the diagnostic value of these indices in ACL injury was evaluated. Additionally, the diagnostic efficacy of these indices was assessed using the Receiver Operating Characteristic (ROC) curve, Area Under Curve (AUC), sensitivity, and specificity. Moreover, patients were followed-up for three months after surgery, and the relationship between postoperative knee function recovery, TPW, and joint effusion was evaluated.</p><p><strong>Results: </strong>The injury group demonstrated a significantly higher TPW than the control group (p < 0.001). Similarly, the joint effusion volume was significantly greater in the injury group compared to the control group (p < 0.01). The AUC of TPW was 0.826 (95% confidence interval (CI): 0.745-0.906), with a sensitivity of 66.10% and a specificity of 89.50%. However, the AUC of joint effusion was 0.691 (95% CI: 0.579-0.803), with a sensitivity of 85.50% and a specificity of 52.60%. Furthermore, the AUC of the joint index was 0.864 (95% CI: 0.793-0.936), with a sensitivity of 80.60% and a specificity of 86.80%. Additionally, correlation analysis revealed a negative correlation between TPW (r = -0.355, p < 0.001), joint effusion (r = -0.375, p < 0.001), and postoperative knee function recovery.</p><p><strong>Conclusions: </strong>MRI-measured TPW and joint effusion volume hold significantly diagnostic value in assessing ACL injuries associated with tibial plateau fractures and correlate with the patient's postoperative knee functional recovery. These metrics may provide clinicians with important diagnostic and prognostic insights and help formulate individualized treatment plans.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 3","pages":"400-408"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143639410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Delayed Traumatic Splenic Rupture as a Life-threatening Clinical Manifestation Treatable with Splenectomy: A Study of Twelve Cases and Literature Review.","authors":"Jiachen Zhang, Genfei Zhu, Ling Liu, Sunbing Xu, Changku Jia","doi":"10.62713/aic.3767","DOIUrl":"https://doi.org/10.62713/aic.3767","url":null,"abstract":"<p><strong>Aim: </strong>While most splenic ruptures manifest as immediate hemorrhage, a minority of patients experience delayed rupture, which occurs days to weeks after the initial trauma. Although there have been reports of delayed splenic rupture following trauma, the exact pathophysiology of this condition and the appropriate treatment remain contentious. This article aims to further discuss and summarize the diagnosis and treatment protocols for delayed traumatic rupture of the spleen through the collection and analysis of existing clinical data, combined with previous literature.</p><p><strong>Case presentation: </strong>From 2012 to 2023, we identified 12 adults admitted to a trauma center with delayed traumatic rupture of the spleen (DRS). After excluding unrelated cases, we focused on patients with a definitive DRS diagnosis. The majority were male, aged 46-90 years, with some having pre-existing conditions like cirrhosis or cancer. Most injuries were from falls or car accidents, occurring 2-7 days before admission. Five patients had additional traumatic injuries. All experienced left-side abdominal pain and were diagnosed using imaging. They received medical intervention to stabilize their condition, with initial hemoglobin levels slightly low.</p><p><strong>Results: </strong>Clinical data of 12 splenic rupture cases presenting with symptoms between 2 and 7 days after splenic trauma but without any pre-existing splenic pathology were collected from November 2012 to August 2023. Among these cases, 8 patients underwent splenectomy immediately following the diagnosis of delayed splenic rupture. For the remaining 4 patients, conservative treatment was initially attempted, but due to inadequate control of their condition, the treatment plan was subsequently altered to surgical intervention, yielding favorable clinical outcomes.</p><p><strong>Conclusions: </strong>Delayed splenic rupture is a disease caused by multiple factors. The atypical clinical manifestations of delayed rupture pose challenges to timely and accurate diagnosis, making computed tomography (CT) the preferred diagnostic method for delayed splenic rupture. Emergency surgical treatment is the optimal surgical approach for managing delayed splenic rupture.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 3","pages":"296-308"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143639412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Laparoscopic Treatment of a Huge Epiphrenic Esophageal Diverticulum: A Case Report and Literature Review.","authors":"Agostino Fernicola, Giuseppe Palomba, Marianna Capuano, Giovanni Domenico De Palma, Giovanni Aprea","doi":"10.62713/aic.3802","DOIUrl":"https://doi.org/10.62713/aic.3802","url":null,"abstract":"<p><strong>Aim: </strong>Epiphrenic diverticulum (ED) is a rare benign esophageal disorder commonly associated with esophageal motility conditions, such as achalasia. Esophagogastroduodenoscopy (EGDS), barium esophagography, and esophageal high-resolution manometry (HRM) are essential for accurate diagnosis. Surgical intervention is the standard treatment for symptomatic patients.</p><p><strong>Case presentation: </strong>We present the case of a 61-year-old man with a large epiphrenic diverticulum presenting with dysphagia and chest pain. Medical therapy was ineffective; therefore, the patient underwent laparoscopic diverticulectomy, hiatoplasty, Heller myotomy, and Dor fundoplication.</p><p><strong>Results: </strong>Complete resolution of symptoms was achieved, significantly improving the patient's quality of life, with no perioperative complications.</p><p><strong>Conclusions: </strong>The diagnosis and management of epiphrenic diverticula require a multidisciplinary approach. Abdominal laparoscopic surgery is a safe and effective option, with a low risk of complications and good symptom resolution.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 3","pages":"322-328"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143639433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predicting Success: The Crucial Role of Preoperative Data in Refractive Surgery Outcomes.","authors":"Federico Visalli, Caterina Gagliano, Fabiana D'Esposito, Mutali Musa, Daniele Tognetto, Marco Zeppieri","doi":"10.62713/aic.3778","DOIUrl":"https://doi.org/10.62713/aic.3778","url":null,"abstract":"<p><p>Refractive surgery, which includes techniques such as Laser-Assisted In Situ Keratomileusis (LASIK), Photorefractive Keratectomy (PRK) and Small Incision Lenticule Extraction (SMILE), has revolutionized ophthalmology by offering advanced solutions for vision correction. However, the choice of the technique to be used in the individual patient is highly dependent on a thorough preoperative evaluation. This retrospective study aims to investigate how preoperative parameters, including corneal thickness, topography, and refraction, affect long-term post-operative clinical outcomes. Through a systematic review of the literature published between 2000 and 2023, we identify the main predictors of success for each surgical technique. This study emphasizes the importance of personalized surgical strategies based on meticulous preoperative analysis.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 1","pages":"19-28"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142999050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Efficacy of Automatic Ruiyun Procedure for Hemorrhoids and Procedure for Prolapse and Hemorrhoids in the Treatment of Mixed Hemorrhoids: A Comparative Study.","authors":"Hao Xu, Xinyong Yan, Dongpeng Hao, Jieliang Hu, Yan Wang","doi":"10.62713/aic.3746","DOIUrl":"https://doi.org/10.62713/aic.3746","url":null,"abstract":"<p><strong>Aim: </strong>The occurrence of mixed hemorrhoids becomes increasingly more frequent with age, posing psychological pressure and distress to affected patients. This retrospective study aims to compare the clinical efficacy of automatic Ruiyun procedure for hemorrhoids and procedure for prolapse and hemorrhoids in the treatment of mixed hemorrhoids.</p><p><strong>Methods: </strong>A retrospective cohort study of patients with mixed hemorrhoids who visited the Third Affiliated Hospital of Gansu University of Chinese Medicine (The 1st People's Hospital of Baiyin) from January 2019 to December 2023 was conducted using propensity score matching (PSM) with a ratio of 1:1 for nearest neighbor matching grouping. In this study, 60 cases were grouped under the Ruiyun procedure for hemorrhoids (RPH) group, and the other 60 cases were categorized in the procedure for prolapse and hemorrhoids (PPH) group. The postoperative medical humanistic evaluation, clinical efficacy evaluation, subjective evaluation of patients, the occurrence of complications and the rate of unplanned readmission were compared between the two groups.</p><p><strong>Results: </strong>Surgical time, intraoperative blood loss, duration of postoperative pain, length of hospital stay and hospitalization expenses between the two groups presented statistically significant differences (p < 0.001). There were statistically significant intra-group and between-group differences between RPH group and PPH group in the visual analogue scale (VAS) scores on the 4th and 6th postoperative days (p < 0.001). The European Quality of Life-5 Dimensions, 5-Level Version (EQ-5D-5L) score in the RPH group was lower than that in the PPH group at the 12th week of follow-up (p < 0.001), signifying an improved level of quality of life. There was no difference in Vaizey's Fecal Incontinence Rating Scale score between the RPH group and the PPH group at the 12th week of follow-up (p > 0.05). The rate of unplanned postoperative readmission was higher in the PPH group than in the RPH group, although the difference was not of statistical significance (p > 0.05).</p><p><strong>Conclusions: </strong>RPH outperforms PPH in the treatment of mixed hemorrhoids with a shortened surgical time.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 2","pages":"205-212"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143432352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing the Effect of Neuroendoscopic Surgery on Cerebral Hemodynamics and Functional Recovery in Patients With Brain Hemorrhage.","authors":"Yuanbao Kang, Quanming Zhou","doi":"10.62713/aic.3907","DOIUrl":"https://doi.org/10.62713/aic.3907","url":null,"abstract":"<p><strong>Aim: </strong>This study aims to investigate the impact of neuroendoscopic surgery on cerebral hemodynamics and functional recovery in patients with different brain hemorrhage severities.</p><p><strong>Methods: </strong>This study included 161 patients with brain hemorrhage who were admitted to the Affiliated Hospital of Putian University, China, between January 2021 and January 2022. Patients were divided into a neuroendoscopy group and a minimally invasive drilling group based on the surgical techniques. Furthermore, patients in the neuroendoscopy group were further stratified into mild, moderate, and severe subgroups based on their Glasgow Coma Scale (GCS) scores. Surgical outcomes, including hemorrhage volume, hematoma clearance rate, surgical duration, and postoperative hemorrhage volume, were compared between the two groups. Additionally, cerebral hemodynamic parameters, such as critical pressure (CP), mean blood flow quantity (Qmean), peripheral resistance (Rv), mean blood flow velocity (Vm), and pulsatility index (PI), were recorded before surgery and 7 days postoperatively. Functional recovery was assessed using the National Institutes of Health Stroke Scale (NIHSS), the Fugl-Meyer Assessment (FMA), and the Coma Recovery Scale-Revised (CRS-R).</p><p><strong>Results: </strong>Compared to the minimally invasive drilling group, the neuroendoscopy group exhibited greater intraoperative hemorrhage volume (p < 0.001), higher hematoma clearance rate at 24 hours post-surgery (p < 0.001), longer surgical duration (p < 0.001), and lower postoperative hemorrhage volume (p < 0.001). However, 7 days postsurgery, the neuroendoscopy group demonstrated significantly higher Qmean (p < 0.001) and Vm (p < 0.001) and lower CP (p < 0.001), Rv (p < 0.001), and PI (p < 0.001) compared to the minimally invasive drilling group. Within the neuroendoscopy group, patients in the severe subgroup had higher PI values 7 days after surgery than those in the mild and moderate subgroups. Assessment of functional recovery outcomes indicated that the neuroendoscopy group had greater improvements, with significantly lower NIHSS scores (p < 0.01) and higher FMA (p < 0.01) and CRS-R scores (p < 0.01) compared to the minimally invasive drilling group. Furthermore, mild and moderate subgroups showed greater reductions in NIHSS scores (p < 0.05) and increases in FMA (p < 0.05) and CRS-R scores (p < 0.05) than the severe subgroup.</p><p><strong>Conclusions: </strong>Neuroendoscopic treatment may effectively improve cerebral hemodynamics and promote functional recovery in patients with brain hemorrhage, with the impacts being more pronounced in patients with mild or moderate hemorrhage compared to those with severe conditions.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 3","pages":"371-379"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143639392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Small Bowel Volvulus Caused by Meckel's Diverticulum.","authors":"Roberto Cammarata, Vincenzo La Vaccara, Silvia Angeletti, Lucrezia Bani, Roberto Coppola, Damiano Caputo","doi":"10.62713/aic.3883","DOIUrl":"https://doi.org/10.62713/aic.3883","url":null,"abstract":"<p><p>No abstract present.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"96 3","pages":"282-285"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143639417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spontaneous Complete Regression of Breast Cancer: Two Case Report.","authors":"Orhan Yılmaz, Ugur Kesici, Mehmet Guray Duman, Ozgur Yuzer, Asli Erturk, Pinar Ozay Nayir","doi":"10.62713/aic.3461","DOIUrl":"10.62713/aic.3461","url":null,"abstract":"<p><p>Spontaneous regression (SR) is a tumor's partial or complete disappearance without any treatment. In the literature, it has been documented that SR is uncommon in breast cancer (BC) and other types of cancer. Multiple mechanisms are believed to contribute to the development of SR. However, its mechanism still needs to be clearly demonstrated. Although two SR patients were presented in our study, the evidence needed to be more sufficient to determine the mechanism. However, due to Programmed Death-Ligand 1 (PD-L1) negativity in both patients, the hypothesis in the literature that PD-L1 has strong antitumoral activity was not supported. In addition, it was determined that the patient in case 2 was the first Cerb B2 positive case reported in the literature and had the earliest SR period. Due to this, it has been disclosed that the SR mechanism of BC will be concluded within 21 days at the earliest. This situation suggests that breast surgeons, in particular, should conduct a thorough physical examination and, if necessary, re-radiological examination before surgery on patients for whom surgery is decided after diagnosis. Being careful in this regard may increase the number of SR in BC cases and allow molecular investigations on living tissue samples to reveal the underlying mechanism.</p>","PeriodicalId":8210,"journal":{"name":"Annali italiani di chirurgia","volume":"95 5","pages":"767-771"},"PeriodicalIF":0.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142520758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}