Journal of Analytical Atomic Spectrometry最新文献

{"title":"Enhanced quantitative elemental analysis in XRF spectroscopy using deep learning fusion network","authors":"Mohai Yue, Qi Zhang, Xiangjun Xin, Ran Gao, Jiajie Li, Lan Rao, Yuwen Qin, Fugen Wu, Zhongfei Mu, Feng Tian, Yun Teng, Fu Wang, Yongjun Wang and Qinghua Tian","doi":"10.1039/D5JA00208G","DOIUrl":"https://doi.org/10.1039/D5JA00208G","url":null,"abstract":"<p >To address the limited accuracy in quantitative elemental analysis caused by insufficient integration of multi-energy state X-ray fluorescence (XRF) spectral data, an effective deep learning method is proposed to optimize element quantitative analysis. This method constructs a novel Multi-energy State Attention Fusion Network (MSAF-Net). Firstly, to prevent important peaks from being obscured by noise, a Spectral Feature Extraction Module (SFEM) is proposed to adaptively weight spectral data, enhancing meaningful peaks while suppressing background interference. Secondly, to ensure balanced information integration across energy states, a Dynamic Fusion Scoring Module (DFSM) is developed to learn and apply distinct weights to each state and evaluate the fused output through a pre-training scoring mechanism. Finally, a two-stage optimization strategy is implemented to overcome local optima and promote comprehensive information sharing during model training: individual pre-training of each energy branch followed by constrained joint training, yielding stable and cumulative performance improvements. Transfer learning was employed to evaluate network generalization. The model was trained on 9855 simulated soil spectra and validated using 118 field samples. Compared to other advanced models, MSAF-Net achieved the highest coefficients of determination (<em>R</em><small>²</small>) of 0.9832, 0.9844, 0.9891, 0.9695, 0.9854, and 0.9801 for Si, Al, Fe, Mg, Ca, and K, respectively, each with a Ratio of Performance to Deviation (RPD) above 7.5. Heavy metal concentrations were predicted with comparable fidelity, with a mean <em>R</em><small>²</small> above 0.98, demonstrating excellent fit quality and robust error control. These results establish MSAF-Net as an efficient and reliable tool for quantitative elemental analysis in XRF spectroscopy.</p>","PeriodicalId":81,"journal":{"name":"Journal of Analytical Atomic Spectrometry","volume":" 10","pages":" 2923-2936"},"PeriodicalIF":3.1,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145196117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility study to evaluate composition and degradation of orichalcum ingots through combined XRF and VIS-SWIR reflectance mapping","authors":"Anna Galli, Jacopo Orsilli, Adele Sassella, Luisa Raimondo, Simone Caglio, Maria Luisa Saladino, Francesco Armetta, Mario Berrettoni, Paolo Conti and Eugenio Caponetti","doi":"10.1039/D5JA00241A","DOIUrl":"https://doi.org/10.1039/D5JA00241A","url":null,"abstract":"<p >Non-invasive and multi-analytical approaches are crucial for analyzing cultural heritage artifacts, particularly for rare and fragile specimens that must be studied <em>in situ</em>. The disadvantage of non-invasive techniques is their lower sensitivity and the limited information that can be collected without sampling the artifact; however, they allow the collection of multiple data sets on the same specimen. Besides, non-invasive techniques can collect more sample points or even a map on the same artifact, getting information about the whole object, considering its inhomogeneities due to possible alterations, without being biased by the chosen points. In this work, we employ an integrated instrument capable of simultaneously acquiring X-ray fluorescence and reflectance mapping in the visible-short wave infrared range to analyze orichalcum powder samples, then discussing the results in comparison with the analysis carried out using both <em>in situ</em> non-invasive techniques and laboratory-based non-destructive methods. These reference samples, derived from ingots recovered from a 6th-century BC shipwreck discovered off the coast of Gela, serve as a controlled dataset to validate the performance of the combined mapping approach. The aim is to assess the potential of this dual-modality system, enabling a comprehensive, bulk, and surface, characterization for future <em>in situ</em> applications to the ingots to check and follow the surface degradation phenomena, without the need for sampling.</p>","PeriodicalId":81,"journal":{"name":"Journal of Analytical Atomic Spectrometry","volume":" 10","pages":" 2826-2832"},"PeriodicalIF":3.1,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/ja/d5ja00241a?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145196159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ozone-mediated breakdown of microplastics in aqueous environments","authors":"Markus A. B. Wieland, Sebastian P. Schwaminger, Matthias Elinkmann, Paul M. Stüger, Jörg Feldmann, David Clases and Raquel Gonzalez de Vega","doi":"10.1039/D5JA00226E","DOIUrl":"10.1039/D5JA00226E","url":null,"abstract":"<p >Advanced oxidation processes (AOPs) are increasingly adopted in wastewater treatment to degrade persistent pollutants, including emerging targets such as microplastics (MPs). These particles enter aquatic systems through the fragmentation of bulk plastics and, as their size decreases, exhibit enhanced mobility, surface reactivity, and biological uptake potential. However, the efficiency of AOPs in removing MPs and their nanoscale derivatives (nanoplastics, NPs) remains poorly understood, partly due to the lack of suitable analytical tools. Small MPs and NPs often occur at trace levels and are obscured by colloidal and dissolved background in complex matrices. Moreover, growing evidence suggests that AOPs may promote fragmentation rather than complete degradation. Thus, the focus of this study is to investigate ozone as a reactive agent for MP degradation, using single-particle inductively coupled plasma – mass spectrometry (SP ICP-MS). The formation of nanoscale plastics was qualitatively assessed using dynamic light scattering (DLS). The degradation behaviour of primary MPs such as polystyrene (PS) and polytetrafluoroethylene (PTFE), and secondary MPs generated from bulk poly(methyl methacrylate) (PMMA) and polyvinyl chloride (PVC) was assessed. Ozone exposure led to progressive mass reduction for PS and PMMA, while PTFE and PVC showed greater oxidation resistance. SP ICP-MS revealed detailed transformations in mass, which were projected into size distributions, while DLS confirmed the formation of nanoscale particles in all cases. These findings highlight that ozone-based AOPs can promote nanoplastic formation, underscoring the need to evaluate treatment efficiency not only by particle removal but also with regard to the nature and behaviour of transformation products. The combined use of SP ICP-MS and DLS offers unique insights into MP degradation and the unintended formation of NPs during oxidative treatment, an aspect of particular relevance as AOPs are increasingly integrated into wastewater treatment under the revised European Urban Wastewater Treatment Directive (2024/3019).</p>","PeriodicalId":81,"journal":{"name":"Journal of Analytical Atomic Spectrometry","volume":" 10","pages":" 2870-2878"},"PeriodicalIF":3.1,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12418336/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145038702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Selective separation and quantification of hematite nanoparticles and ionic iron via cloud point extraction and flame atomic absorption spectrometry","authors":"Rafael Soares Stenico, Maycon Lucas de Oliveira and Márcia Andreia Mesquita Silva da Veiga","doi":"10.1039/D5JA00224A","DOIUrl":"https://doi.org/10.1039/D5JA00224A","url":null,"abstract":"<p >The increasing use of nanomaterials (NMs) in materials science, health, and technology has raised concerns regarding their environmental distribution, stability, and toxicity. Iron oxide nanoparticles (IONPs) are notable for their widespread applicability and reactivity. In this context, developing simple, rapid, and environmentally friendly methods for separating and quantifying them is essential. This study proposes a cloud point extraction (CPE) method for the selective separation of hematite nanoparticles (HemNPs) from ionic iron, allowing for their subsequent quantification using flame atomic absorption spectrometry (FAAS). The synthesized HemNPs utilized in this study exhibited 61% crystallinity, forming pseudo-spherical aggregates with a size of 68 ± 15 nm, an individual particle size of 5 ± 1 nm, and a hydrodynamic diameter of 10 ± 1 nm. The optimized CPE conditions involved Triton X-100 (5% v/v) as the nonionic surfactant, EDTA as the complexing agent, a pH of 5, and 0.15 mol L<small>⁻¹</small> of CaCl<small>₂</small> to lower the cloud point temperature. Under these conditions, HemNPs were effectively separated, with recoveries ranging from 85.7% to 103.4% and an enrichment factor of 5. The method was also applied to real water samples, where HemNPs were not quantified, and spike recovery tests showed values above 70%, demonstrating the method's efficiency. To the best of our knowledge, this is the first report combining CPE with FAAS for the determination of HemNPs, providing a cost-effective, solvent-free, and robust alternative for monitoring iron-based nanomaterials in aqueous matrices.</p>","PeriodicalId":81,"journal":{"name":"Journal of Analytical Atomic Spectrometry","volume":" 10","pages":" 2816-2825"},"PeriodicalIF":3.1,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145196158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Potassium and rubidium isotopic analysis using Neoma MC-ICPMS with the collision/reaction cell","authors":"Zhe J. Zhang, Nicole X. Nie and Colin Z. Lin","doi":"10.1039/D5JA00189G","DOIUrl":"https://doi.org/10.1039/D5JA00189G","url":null,"abstract":"<p >Potassium and rubidium isotopes are critical for understanding various geological processes that shape our planet. However, their analysis often encounters significant challenges. This study introduces methods for the simultaneous purification of K and Rb using three-step ion exchange column chromatography, coupled with high-precision isotopic analyses using Thermo Fisher Scientific Neoma MC-ICPMS/MS. This instrument features a double Wien filter and a collision/reaction cell. Using an Apex Omega desolvating nebulizer and low-resolution mode, we achieved sensitivities of 345 V per ppm for <small>³⁹</small>K and 800 V per ppm for <small>⁸⁵</small>Rb and obtained high precision (≤0.05‰; 95% confidence interval) for low-concentration solutions of K (≥20 ng g<small>⁻¹</small>) and Rb (≥5 ng g<small>⁻¹</small>). Our tests indicate that K isotope measurements are largely insensitive to sample/standard concentration mismatches within ±15% but are significantly affected by acid molarity and matrix effects. In particular, elevated concentrations of Mg and Ca introduce a positive <em>δ</em><small>⁴¹</small>K bias, emphasizing the need to maintain total matrix concentrations below 2% for accurate results. Rb isotope measurements, on the other hand, show minimal sensitivity to concentration mismatch within ±20%, and various acid strength from 0.15 to 0.75 mol L<small>⁻¹</small> HNO<small>₃</small>, but are influenced by matrix effects, especially K/Rb ratios. For reliable Rb isotopic data, K/Rb ratios should be kept below 1 with 20% magnetic field of the MS/MS module (<em>B</em>-field). To validate our method, we processed geostandards through column purification, yielding isotopic compositions consistent with those from other measurement techniques. Overall, our findings demonstrate that simultaneous K and Rb isotopic analyses for low concentration samples are feasible using Neoma MC-ICPMS/MS.</p>","PeriodicalId":81,"journal":{"name":"Journal of Analytical Atomic Spectrometry","volume":" 10","pages":" 2945-2956"},"PeriodicalIF":3.1,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/ja/d5ja00189g?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145196119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fully automated dual-column purification procedure for Pb from biological materials for subsequent high-precision isotopic analysis","authors":"Anika Retzmann, Kerri A. Miller, Sebastian Champagne, Gabriella Gelinas and Michael E. Wieser","doi":"10.1039/D5JA00240K","DOIUrl":"https://doi.org/10.1039/D5JA00240K","url":null,"abstract":"<p >A fully automated dual-column purification procedure for Pb from biological samples, designed for subsequent Pb isotopic analysis, is presented that utilizes the prep<em>FAST</em> MC™ system (Elemental Scientific), Nobias Chelate-PA1 resin (Hitachi High-Tech Fielding Corporation) and DGA resin (TrisKem International). The procedure developed allows the unattended processing of approx. 15–20 samples per day and offers several advantages: low and reproducible blanks (&lt;0.05 ng), no carry over or memory effects, high reusability (&gt;50 uses), high Pb yields (99% ± 15%, 2 SD<em>, N</em> = 23), and strong robustness to matrix variations across biological samples (<em>i.e.,</em> bone, hair). Additionally, Pb isotopic analysis using MC-ICP-MS showed no significant on-column fractionation. The measured <small>²⁰⁸</small>Pb/<small>²⁰⁶</small>Pb, <small>²⁰⁷</small>Pb/<small>²⁰⁶</small>Pb, and <small>²⁰⁸</small>Pb/<small>²⁰⁴</small>Pb isotope abundance ratios of biological reference materials (<em>i.e.</em>, NIST SRM 1400, ERM-DB001, GBW07601) are consistent with published values. For the hair reference material GBW09101, a <small>²⁰⁸</small>Pb/<small>²⁰⁶</small>Pb isotope abundance ratio of 2.12045 ± 0.00054 (<em>i.e.</em>, <em>δ</em>(<small>²⁰⁸</small>Pb/<small>²⁰⁶</small>Pb)<small>_SRM981</small> = −21.99‰ ± 0.24‰) (<em>U</em>, <em>k</em> = 2), a <small>²⁰⁷</small>Pb/<small>²⁰⁶</small>Pb isotope abundance ratio of 0.86292 ± 0.00014 (<em>i.e.</em>, <em>δ</em>(<small>²⁰⁷</small>Pb/<small>²⁰⁶</small>Pb)<small>_SRM981</small> = −56.56‰ ± 0.14‰) (<em>U</em>, <em>k</em> = 2), and a <small>²⁰⁸</small>Pb/<small>²⁰⁴</small>Pb isotope abundance ratio of 38.451 ± 0.022 (<em>i.e.</em>, <em>δ</em>(<small>²⁰⁸</small>Pb/<small>²⁰⁴</small>Pb)<small>_SRM981</small> = 47.09‰ ± 0.51‰) (<em>U</em>, <em>k</em> = 2) are proposed.</p>","PeriodicalId":81,"journal":{"name":"Journal of Analytical Atomic Spectrometry","volume":" 10","pages":" 2783-2791"},"PeriodicalIF":3.1,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/ja/d5ja00240k?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145196120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A novel particle mass calibration strategy for the quantification of AuNPs in single cancer cells via laser ablation ICP-mass spectrometry. A case study","authors":"Antonio Bazo, Eduardo Bolea-Fernandez, Kharmen Billimoria, Ana Rua-Ibarz, Maite Aramendía, Paula Menero-Valdés, Jack Morley, Sara Neves, Armando Sánchez-Cachero, Heidi Goenaga-Infante and Martín Resano","doi":"10.1039/D5JA00253B","DOIUrl":"https://doi.org/10.1039/D5JA00253B","url":null,"abstract":"<p >Laser ablation ICP-mass spectrometry (LA-ICP-MS) has developed as a powerful tool for elemental quantitative analysis of individual cells, assuring that the content of each cell is analyzed individually. However, this technique is still limited by the difficulties associated with calibration using solid standards. This work proposes a particle mass calibration strategy that is independent of both the properties and thickness of the gelatin films used for calibration, overcoming a significant drawback of previously established methods. The fundamental principle of this strategy relies on the individual ablation of nanoparticles (NPs) of well-characterized size that are embedded in the films, so that their mass can be directly used for calibration without the need to calculate their exact concentration within the gelatin. The performance of the newly developed method was compared to that of the previously reported approaches (ionic and particle number calibration) in terms of linearity and homogeneity between different films prepared from the same gelatin solution. As a case study, the three calibration strategies were used for the quantitative analysis of HeLa cancer cells exposed to AuNPs. In parallel, in-suspension single-cell (SC) ICP-MS Au data were obtained and used as reference for comparison with the three LA-SC-ICP-MS strategies. The results obtained with the novel particle mass approach demonstrated better accuracy and repeatability over three different working sessions, addressing key limitations and providing a robust and reliable method for quantitative LA-SC-ICP-MS analysis. The particle mass method holds promise for quantitative LA-ICP-MS analysis of samples beyond NP-exposed cells, such as biological tissues.</p>","PeriodicalId":81,"journal":{"name":"Journal of Analytical Atomic Spectrometry","volume":" 10","pages":" 2673-2681"},"PeriodicalIF":3.1,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/ja/d5ja00253b?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145196077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synergistic integration of centrifugal ultrafiltration and superhydrophilic substrates for enhanced sensitivity and stability in laser-induced breakdown spectroscopy","authors":"Yuan Liu, Dehua Zhu, Yu Cao, Jiapeng He, Youzhi Zhang, Fang Zhao and Wei Xue","doi":"10.1039/D5JA00217F","DOIUrl":"https://doi.org/10.1039/D5JA00217F","url":null,"abstract":"<p >Minor variations in serum element concentrations are linked to many diseases, emphasizing the need for sensitive and stable detection methods. Serum analysis faces challenges due to macromolecular interference and non-uniform sample distribution caused by the coffee-ring effect. To address these limitations, a novel methodology integrating centrifugal ultrafiltration with superhydrophilic surface-enhanced laser-induced breakdown spectroscopy (CUSHL-LIBS) has been developed. Centrifugal ultrafiltration isolates macromolecules, reducing interference, while the superhydrophilic substrate suppresses the coffee-ring effect, ensuring uniform sample distribution. Experiments show that this method produces higher plasma signal intensity in serum filtrate than in whole blood or plasma. Repeatability assessments reveal relative standard deviations (RSDs) of 4.49% for calcium (Ca) and 1.98% for potassium (K), whereas quantitative analyses demonstrate detection limits of 0.31 mg L<small>⁻¹</small> for Ca and 0.61 mg L<small>⁻¹</small> for K. These results demonstrate that the CUSHL-LIBS method offers an innovative solution for high-sensitivity and high-stability elemental analysis, with significant potential applications in clinical diagnostics, medical research, and personalized treatment strategies.</p>","PeriodicalId":81,"journal":{"name":"Journal of Analytical Atomic Spectrometry","volume":" 10","pages":" 2725-2736"},"PeriodicalIF":3.1,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145196066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing the impact of common sample preparation strategies for single particle ICP-MS regarding recovery and size distribution of natural single particles","authors":"Lhiam Paton, Sandra Kiesel, Grit Steinhoefel, Matthias Elinkmann, Thebny Thaise Moro, Raquel Gonzalez de Vega, Pascal Bohleber and David Clases","doi":"10.1039/D5JA00170F","DOIUrl":"10.1039/D5JA00170F","url":null,"abstract":"<p >Particles on the nano- and micro-scale are produced in a wide range of natural and anthropogenic processes and play a significant role in the biogeochemical cycling of major and trace elements in the environment. Single particle inductively coupled plasma – mass spectrometry (SP ICP-MS) is quickly becoming one of the premier techniques for analysis of nano- or micro-entities. However, SP ICP-MS analysis requires dilute aqueous solutions, free from large particles that could cause blockages. For environmentally relevant samples, like soil extracts, this typically calls for sample clean up. Sample preparation strategies like syringe filtration or ultra-centrifugation are regularly applied to handle complex matrices. The aim of this article is to examine the influence of common preparative strategies on the analysis of both naturally formed and synthetic nanoparticles in complex matrices. To achieve this, water extracts of mineral and sediment standards were spiked with Au nanoparticles and a variety of chemical and physical approaches were investigated to identify which strategies provide the best route to accurately quantifying particle numbers, masses and sizes. In a vast majority of cases, at least 90% of the detectable particles were lost for both particle types whenever filtration or centrifugation was applied. The addition of surfactants like Triton X-100 proved to promote relative particle recoveries of up to 30% for spiked Au particles but the extracted Fe-containing particles continued to have losses of up to 99%. Therefore, common sample preparation strategies are directly impeding the possibilities for quantitative particle analysis by SP ICP-MS. Furthermore, commonly used nanoparticles like Au do not necessarily reflect the reality of nano- and microparticles found in the environment. It is apparent that for SP ICP-MS to become a useful, quantitative method for environmental analysis there must be a high degree of care taken in the collection and preparation stages of analysis.</p>","PeriodicalId":81,"journal":{"name":"Journal of Analytical Atomic Spectrometry","volume":" 10","pages":" 2897-2908"},"PeriodicalIF":3.1,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12426992/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145062903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High precision selenium isotope analysis using a Nu Sapphire collision–reaction cell MC-ICP-MS","authors":"Michael A. Kipp, Laura F. Piccirillo and Daniel Peters","doi":"10.1039/D5JA00247H","DOIUrl":"https://doi.org/10.1039/D5JA00247H","url":null,"abstract":"<p >Selenium is a redox-sensitive trace element that is both an essential nutrient and toxin. Studying selenium cycling in nature is of great interest to the fields of environmental health, geomicrobiology, chemical oceanography and volcanology. The six stable isotopes of selenium are fractionated during redox reactions, leaving fingerprints of redox conditions and micronutrient dynamics in modern and ancient environments. However, the study of selenium isotope variability in nature is plagued by analytical difficulties, including its low natural abundance and the prevalence of argon-based interferences in plasma-based mass spectrometers. Here we present a new approach to selenium isotopic analysis using a collision–reaction cell multiple collector inductively coupled plasma mass spectrometer. By using a He–N<small>₂</small> gas mixture, we can achieve near-complete removal of argon dimers from the beam, allowing precise analysis of all selenium isotopes. This new method enables greater analytical precision per nanogram of selenium analyzed and is also less sensitive to concentration mismatch between samples and standards. Future work can leverage CRC-equipped mass spectrometers to study subtle isotopic effects in low-selenium reservoirs.</p>","PeriodicalId":81,"journal":{"name":"Journal of Analytical Atomic Spectrometry","volume":" 10","pages":" 2792-2802"},"PeriodicalIF":3.1,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/ja/d5ja00247h?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145196156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}