Evilim M. Oliveira, Edilene C. Ferreira, José A. Gomes Neto, George L. Donati and Bradley T. Jones
{"title":"Multi-laser-power calibration for quantitative determination of N and P in fertilizers by Raman spectroscopy†","authors":"Evilim M. Oliveira, Edilene C. Ferreira, José A. Gomes Neto, George L. Donati and Bradley T. Jones","doi":"10.1039/D4JA00451E","DOIUrl":"https://doi.org/10.1039/D4JA00451E","url":null,"abstract":"<p >A new method called multi-laser-power calibration (MLPC) is described for quantitative analysis by Raman spectroscopy. MLPC is based on the premise that, under controlled operating conditions, the intensity of Raman spectroscopy signals for a given analyte is directly proportional to the laser power applied to generate that signal. Different from traditional methods, in which calibration is performed by varying analyte concentrations while keeping instrumental parameters fixed, MLPC uses a single calibration standard and different laser applied powers to generate several calibration points. Samples and standard solution are measured under identical conditions, and multiple scattering intensities (<em>I</em>) are generated by varying the Raman's laser applied power (<em>P</em>). The MLPC curve is built with <em>I</em> values for the calibration standard (<em>I</em><small><sup>std</sup></small>) on the <em>x</em> axis and the respective values for the sample (<em>I</em><small><sup>sample</sup></small>) on the <em>y</em> axis. The analyte concentration in the sample (<em>C</em><small><sup>sample</sup></small>) is then calculated from the calibration curve slope (<em>m</em>). As a proof-of-concept, the MLPC method was applied for the determination of N and P species in fertilizer and raw material samples using a 30 s exposition time and laser applied powers in the 35–319 mW range. Calibration curves with correlation coefficients greater than 0.9986 were consistently obtained. The method's accuracy was evaluated by analyzing three certified reference materials of fertilizer. MLPC results were in agreement with reference values at a 95% confidence level (<em>t</em>-test). Ten commercially available fertilizer and raw material samples were also analyzed, and the results were compared with values obtained by both Raman spectroscopy using external standard calibration (EC-Raman), and official methods based on Kjeldahl and spectrophotometry. Limits of quantification (dry mass, % w/w) for phosphate, phosphite, urea, and nitrate were calculated as 0.03, 0.09, 0.04, 0.05, respectively. Relative standard deviations (RSDs) were 10%, 7%, 11%, and 3% (9%, 4%, 9%, and 2% for EC), respectively, for these analytes. Total N and total P determination by Kjeldahl and spectrophotometry had RSDs of 4% and 10%, respectively. The MLPC method using 5000 mg L<small><sup>−1</sup></small> single calibration standards was successfully used to speciate N and P in fertilizer analyses.</p>","PeriodicalId":81,"journal":{"name":"Journal of Analytical Atomic Spectrometry","volume":" 5","pages":" 1231-1240"},"PeriodicalIF":3.1,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143913747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Benjamin T. Manard, Sarah E. Szakas, Jordan S. Stanberry, Brian W. Ticknor, Leslie O'Brien, Mark Boris, Joshua T. Hewitt, Paula Cable-Dunlap and Hunter B. Andrews
{"title":"Evaluating the feasibility of LA-ICP-TOF-MS for the analysis of environmental particle collections†","authors":"Benjamin T. Manard, Sarah E. Szakas, Jordan S. Stanberry, Brian W. Ticknor, Leslie O'Brien, Mark Boris, Joshua T. Hewitt, Paula Cable-Dunlap and Hunter B. Andrews","doi":"10.1039/D5JA00009B","DOIUrl":"https://doi.org/10.1039/D5JA00009B","url":null,"abstract":"<p >Laser ablation-inductively coupled plasma-time-of-flight-mass spectrometry (LA-ICP-TOF-MS) was employed to rapidly analyze environmental particle samples collected using aerosol contaminate extractors (ACE). The ACE particle collectors were placed at various distances (0.5, 1.3, and 4.5 km) from a source that released Ru-bearing particles. Samples for measurement were then generated (as sub-samples) from the ACE collection plates <em>via</em> particle “lift off” with gunshot residue (GSR) tabs. The LA-ICP-TOF-MS method was employed such that 10+ samples could be analyzed in a single unattended analytical session. A 3 × 1 mm area of individual GSR tab samples were analyzed in less than 30 minutes. This provided spatially resolved elemental and isotopic measurements of the particulate content and confirmed the presence of Ru-bearing particles within the complex background environmental particle loading. As anticipated, measurements showed collectors closest to the source had the highest concentration of the released Ru-bearing particles, while all collectors, regardless of distance, contained similar levels of background particles (<em>e.g.</em>, Fe and Sr). Sequential scanning electron microscopy – automated particle analysis (SEM-APA) and LA-ICP-TOF-MS analysis was employed for method validation and a demonstration of the multi-modal approach. The same 2-dimensional region was analyzed by both methods and the particles identified <em>via</em> SEM-APA were also detected using LA-ICP-TOF-MS, with 100% accuracy. Overall, LA-ICP-TOF-MS demonstrated its utility for rapid elemental and isotopic particle analysis from environmental air samples.</p>","PeriodicalId":81,"journal":{"name":"Journal of Analytical Atomic Spectrometry","volume":" 5","pages":" 1241-1248"},"PeriodicalIF":3.1,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/ja/d5ja00009b?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143913748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Spatial distribution characteristics of atmospheric pressure solution cathode glow discharge plasma based on Abel inversion†","authors":"Peichao Zheng, Jingtong Zhou, Jinmei Wang, Jiali Liu, Wei Li, Biao Li, Lianbo Guo, Hongwu Tian and Daming Dong","doi":"10.1039/D4JA00421C","DOIUrl":"https://doi.org/10.1039/D4JA00421C","url":null,"abstract":"<p >The Abel inversion was employed to investigate the radial emissivity distribution of solution cathode glow discharge (SCGD) of plasma. Results showed that, following the Abel inversion, the radial emissivity of the element initially increases and then subsequentiy decreases. The electron number density and electronic excitation temperature in the radial distribution of the plasma exhibited a minimum at the center. Detection limits for eight metals (K, In, Rb, Ag, Ca, Cu, Mn, and Cd) were assessed at the positions of central and maximum emissivity, showing improvements by a factor ranging from 1.1 to 4.0 at the extremum positions following the Abel inversion. These findings suggest optimization strategies for the detection of various types of elements, and provide a theoretical basis for precise detection and application in SCGD plasma.</p>","PeriodicalId":81,"journal":{"name":"Journal of Analytical Atomic Spectrometry","volume":" 5","pages":" 1284-1296"},"PeriodicalIF":3.1,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143913762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nuria Guijarro-Ramírez, Iraide Sáez-Zamacona, Guillermo Grindlay, Luis Gras and Rosa María Martínez-Espinosa
{"title":"Improving detection capabilities of biogenic selenium nanoparticles in spICP-MS using an anionic ion-exchange resin†","authors":"Nuria Guijarro-Ramírez, Iraide Sáez-Zamacona, Guillermo Grindlay, Luis Gras and Rosa María Martínez-Espinosa","doi":"10.1039/D5JA00005J","DOIUrl":"https://doi.org/10.1039/D5JA00005J","url":null,"abstract":"<p >Single particle inductively coupled plasma mass spectrometry (spICP-MS) is widely used for characterizing Se nanoparticles (SeNPs) biosynthesized by several microorganisms when exposed to Se oxyanions. However, characterization is challenging due to the high levels of dissolved ionic Se in cell culture media, particularly at short incubation times. This study demonstrates that employing an anionic ion-exchange resin (Amberlyst A-26) to remove dissolved Se species (SeO<small><sub>3</sub></small><small><sup>2−</sup></small> and SeO<small><sub>4</sub></small><small><sup>2−</sup></small>) enhances the spICP-MS characterization of biogenic SeNPs. Extraction conditions were initially investigated (<em>i.e.</em>, resin amount, dissolved ionic Se concentration, extraction time and matrix effects), achieving quantitative removal of ionic Se without affecting nanoparticle concentration or size distribution. The resin treatment reduced the background signal by approximately eightfold and lowered the particle size detection limit (LoD<small><sub>size</sub></small>) from >40 nm to 20 nm. This methodology was successfully used to characterize biogenic SeNPs produced by <em>H. mediterranei</em> at 24 and 60 h of incubation.</p>","PeriodicalId":81,"journal":{"name":"Journal of Analytical Atomic Spectrometry","volume":" 5","pages":" 1158-1163"},"PeriodicalIF":3.1,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/ja/d5ja00005j?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143913697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marco Colombo, Thomas Lehmann, Wolfgang Ensinger and Valentina Rossi
{"title":"Application of mobile-macroscale scanning X-ray fluorescence (mobile-MA-XRF) imaging in paleontology: analyses of vertebrate fossil specimens from Messel conserved in different solid and liquid media†","authors":"Marco Colombo, Thomas Lehmann, Wolfgang Ensinger and Valentina Rossi","doi":"10.1039/D4JA00310A","DOIUrl":"https://doi.org/10.1039/D4JA00310A","url":null,"abstract":"<p >Cutting-edge analytical instrumentation is increasingly being developed and applied to the analysis of fossils. X-ray fluorescence (XRF) imaging spectroscopy is a powerful tool to resolve the elemental chemistry of fossil specimens. Most of the XRF application to study fossils is carried out at dedicated synchrotron radiation XRF beamlines. Recent studies used laboratory scanners, <em>i.e.</em> stationary instruments with a measurement chamber or mobile ones to tackle paleontological questions. The application of these new XRF systems on fossils is still relatively limited and clear protocols for the acquisition and processing of the XRF data are currently lacking. Here, we present the use of mobile-macroscale scanning XRF (mobile-MA-XRF) imaging for the <em>in situ</em> analyses of the elemental chemistry of fossil vertebrates from the Messel biota (∼48 Ma, Eocene), including amphibians, reptiles, mammals and birds. We investigate the usefulness of mobile-MA-XRF to detect tissue-specific elemental signatures in fossils preserved in solid resin, liquid glycerin and water. We found remarkable tissue-specific chemical signatures preserved in almost all specimens analyzed. Hair and feathers are associated with S and Ti, abdominal tissues with Cu and Zn and stomach contents, <em>e.g.</em>, seeds, are associated with Ni, Cu, and Zn. We provide a detailed protocol for acquisition and processing of MA-XRF data and a critical discussion of the application of this approach to paleontological research. Our work sets the foundation for applying MA-XRF to the analyses of those fossils that cannot be measured at synchrotron facilities and/or with stationary laboratory scanners due to their dimensions, weights and conservation mode.</p>","PeriodicalId":81,"journal":{"name":"Journal of Analytical Atomic Spectrometry","volume":" 4","pages":" 989-1005"},"PeriodicalIF":3.1,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/ja/d4ja00310a?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143761635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lahcen El Amri, Hamid Amsil, Omar El Bounagui, Brahim Elmokhtari, Hamid Bounouira and Abdessamad Didi
{"title":"An automatic efficiency calibration method with high precision for HPGe detectors","authors":"Lahcen El Amri, Hamid Amsil, Omar El Bounagui, Brahim Elmokhtari, Hamid Bounouira and Abdessamad Didi","doi":"10.1039/D4JA00454J","DOIUrl":"https://doi.org/10.1039/D4JA00454J","url":null,"abstract":"<p >The method used by gamma spectrum analysis software often has a single formula to calibrate efficiency, which is imposed at some reference point sometimes located far from the efficiency curve. The method presented in this article uses four different formulas (can also use more than four) and by using a computer algorithm the efficiency can be automatically calibrated by choosing the closest formula to each point of the data efficiency. This method suggests dividing the energies into three categories: low, medium and high energies. Subsequently, the average of the errors is calculated for each suggested formula, which allows choosing the most accurate formula for each energy range. Finally, a comprehensive efficiency curve is obtained by merging the three selected formulas. In addition, free and open source software named AEC (Automatic Efficiency Calibration) has been created to implement this method. This software offers users an additional tool to existing gamma spectrum analysis software in addition to specifying the efficiency calibration. The AEC is available on GitHub (https://github.com/LAHCEN-EL-AMRI/AEC-v1) and a detailed PDF guide is also included in the software to simplify its use (https://github.com/LAHCEN-EL-AMRI/AEC-v1/blob/main/Doc/guide.pdf).</p>","PeriodicalId":81,"journal":{"name":"Journal of Analytical Atomic Spectrometry","volume":" 4","pages":" 1106-1112"},"PeriodicalIF":3.1,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143761618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Haoyu Dong, Xi Huang, Luke Wadle, Lanh Trinh, Peizi Li, Jean-Francois Silvain, Bai Cui and Yongfeng Lu
{"title":"Machine learning-assisted laser-induced breakdown spectroscopy for estimating substrate surface temperatures†","authors":"Haoyu Dong, Xi Huang, Luke Wadle, Lanh Trinh, Peizi Li, Jean-Francois Silvain, Bai Cui and Yongfeng Lu","doi":"10.1039/D4JA00437J","DOIUrl":"https://doi.org/10.1039/D4JA00437J","url":null,"abstract":"<p >Laser-Induced Breakdown Spectroscopy (LIBS) has been widely used across industries, medical applications, and environmental monitoring for elemental identification and concentration analysis due to its high accuracy, speed, and efficiency. Beyond elemental identification and concentration analysis, many studies suggest that LIBS signal intensities are influenced by sample surface temperatures, presenting an opportunity for temperature monitoring in processes such as three-dimensional additive manufacturing. In such applications, accurately detecting local temperatures at printing spots of interest is critical, specifically in ceramic printing, where phase transitions require temperatures exceeding one thousand degrees Celsius. Due to the dynamic nature of plasma emissions and experimental variability, there are few reports on the use of LIBS for monitoring sample surface temperatures. The direct use of absolute LIBS intensities is challenging for this purpose. Instead, this study explored the use of intensity ratios for surface temperature estimation. A series of LIBS spectra over wavelengths from 430.96 to 438.99 nm were collected from zirconium carbide (ZrC) at temperatures ranging from 350 to 600 °C. Intensity ratios, including atomic-to-atomic, ionization-to-ionization, and atomic-to-ionization line ratios, were evaluated. These ratios demonstrated significant exponential correlations with surface temperatures. Among the regression models, the highest <em>R</em>-squared (<em>R</em><small><sup>2</sup></small>) value of 0.976 was observed for the intensity ratio of Zr II 435.974 nm to Zr I 434.789 nm. Additionally, machine learning algorithms were applied for full LIBS spectrum analysis, enabling comprehensive classification and prediction of sample surface temperatures without relying solely on a single intensity ratio. This strategy has demonstrated the potential of machine learning-assisted LIBS for real-time detection of sample surface temperatures in complex and dynamic environments.</p>","PeriodicalId":81,"journal":{"name":"Journal of Analytical Atomic Spectrometry","volume":" 5","pages":" 1249-1257"},"PeriodicalIF":3.1,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/ja/d4ja00437j?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143913759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Developing a new method for analyzing carbonate-associated phosphate through inductively coupled plasma-tandem mass spectrometry (ICP-MS/MS)","authors":"Wei Liu, Limin Zhou and Jundong Hu","doi":"10.1039/D4JA00429A","DOIUrl":"https://doi.org/10.1039/D4JA00429A","url":null,"abstract":"<p >Phosphorus, a critical biogeochemical element regulating marine productivity, poses analytical challenges in carbonate matrices using conventional spectrophotometric methods. This study establishes novel analytical protocols employing inductively coupled plasma-tandem mass spectrometry (ICP-MS/MS) with oxygen reaction mode and argon gas dilution (AGD)-ICP-MS/MS for simultaneous quantification of carbonate-associated phosphate (CAP) and rare earth elements plus yttrium (REE + Y). Through systematic optimization, we implemented a 2% v/v acetic acid partial leaching protocol for CAP extraction. Comparative evaluation of collision/reaction cell modes revealed that the triple quadrupole configuration with O<small><sub>2</sub></small> reaction gas mode (TQ-O<small><sub>2</sub></small>) demonstrated superior interference elimination capabilities, particularly effective in resolving the [<small><sup>14</sup></small>N<small><sup>16</sup></small>O<small><sup>1</sup></small>H]<small><sup>+</sup></small> isobaric interference on <small><sup>31</sup></small>P<small><sup>+</sup></small> (with a mass shift to <em>m</em>/<em>z</em> 47 for [<small><sup>31</sup></small>P<small><sup>16</sup></small>O]<small><sup>+</sup></small>). The developed methods achieved detection limits of 0.15 μg L<small><sup>−1</sup></small> (ICP-MS/MS) and 2.56 μg L<small><sup>−1</sup></small> (AGD-ICP-MS/MS) for phosphorus, with good determination coefficient (<em>R</em><small><sup><em>2</em></sup></small> > 0.999). Method validation using four geochemical certified reference materials (JDo-1, AGV-2, BHVO-2 and BCR-2) demonstrated excellent agreement with certified values. The CAP/(Ca + Mg) ratios for JDo-1, SRM 1d, and GBW07108 were determined to provide interlaboratory comparative information. This multi-parameter analytical framework provides enhanced throughput for paleoceanographic studies requiring coupled nutrient (P) and redox proxy (REE + Y) analysis.</p>","PeriodicalId":81,"journal":{"name":"Journal of Analytical Atomic Spectrometry","volume":" 4","pages":" 967-974"},"PeriodicalIF":3.1,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143761633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tiantian Zhang, Jie Lin, Xi Zhu, Ao Yang, Kexin Deng, Zhaochu Hu and Yongsheng Liu
{"title":"Investigating the mechanism that reduces the memory effect of Li on MC-ICP-MS†","authors":"Tiantian Zhang, Jie Lin, Xi Zhu, Ao Yang, Kexin Deng, Zhaochu Hu and Yongsheng Liu","doi":"10.1039/D5JA00031A","DOIUrl":"https://doi.org/10.1039/D5JA00031A","url":null,"abstract":"<p >The memory effect significantly impacts the precision and accuracy of lithium isotope measurements using MC-ICP-MS. This study evaluates the origin of the memory effect, identifying the cones, especially the skimmer cone, as the primary site responsible for lithium memory accumulation. To investigate the type and optimal concentration of sodium-containing solutions, scanning electron microscope (SEM) and cone elution experiments were conducted. Results demonstrated that a 0.5% NaNO<small><sub>3</sub></small> solution was the most effective based on the high signal-to-blank ratio, less impacted signal intensity and non-interferences. Combined with the SEM results and KCl elution experiments, the mechanism by which the Na solution reduces the lithium memory effect can be attributed to two aspects. First, a nanoscale particle coating is formed on the cone surface, preventing the deposition of Li material on the cone. Second, Na/K solutions are preferentially ionized due to their low ionization energies, reducing or even eliminating the ionization of the analyzed Li. Based on these findings, we infer that high-concentration rinse solutions of alkali or alkaline earth metals may effectively reduce the memory effect of other related elements.</p>","PeriodicalId":81,"journal":{"name":"Journal of Analytical Atomic Spectrometry","volume":" 5","pages":" 1220-1230"},"PeriodicalIF":3.1,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/ja/d5ja00031a?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143913746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sean R Scott, Gabrielle L Turner, Brandy N Gartman, Sonia Alcantar Anguiano, Kali M Melby, Barbara E Allen, Travis D Minton, Matthew A RisenHuber and Kirby P Hobbs
{"title":"Lithium isotope analysis on the Neoma MS/MS MC-ICP-MS","authors":"Sean R Scott, Gabrielle L Turner, Brandy N Gartman, Sonia Alcantar Anguiano, Kali M Melby, Barbara E Allen, Travis D Minton, Matthew A RisenHuber and Kirby P Hobbs","doi":"10.1039/D4JA00419A","DOIUrl":"https://doi.org/10.1039/D4JA00419A","url":null,"abstract":"<p >Lithium isotopes are measured routinely using multi-collector inductively coupled plasma mass spectrometry due to the high throughput and high measurement precision capabilities of this technique. To obtain high precision isotopic data, lithium is generally purified through ion exchange resins to reduce compositional matrix effects and minimize isobaric interferences when analyzed in solution. In this work, we demonstrate that the ThermoScientific Neoma MS/MS MC-ICP-MS can be used to measure high precision lithium isotopic ratios after purification for a variety of geological and environmental matrices. While the double-Wien filter of the Neoma MS/MS requires additional considerations for measuring lithium isotopes compared to previous generation instruments, high precision lithium isotope ratios can be achieved with proper tuning of the lenses. We provide a strategy for optimization of <small><sup>6</sup></small>Li/<small><sup>7</sup></small>Li measurements for precision and measurement stability, and show our long-term reproducibility for NIST924a and IRMM-016 was 0.8‰ and 0.5‰, respectively. In addition, we provide new <small><sup>6</sup></small>Li/<small><sup>7</sup></small>Li measurements for several environmental reference materials without Li isotope data in the literature, including NIST SRMs 1646a, 2706, 2711a, 2780a, and 4350b.</p>","PeriodicalId":81,"journal":{"name":"Journal of Analytical Atomic Spectrometry","volume":" 4","pages":" 1098-1105"},"PeriodicalIF":3.1,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/ja/d4ja00419a?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143761617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}