Archives of Disease in Childhood - Fetal and Neonatal Edition最新文献

筛选
英文 中文
Surfactant therapy via thin catheter in newborn infants in Ireland. 爱尔兰新生儿细导管表面活性剂治疗。
IF 3.9 2区 医学
Archives of Disease in Childhood - Fetal and Neonatal Edition Pub Date : 2025-03-26 DOI: 10.1136/archdischild-2025-328624
Robert Thomas Joyce, Lisa K McCarthy, Colm Patrick Finbarr ODonnell
{"title":"Surfactant therapy via thin catheter in newborn infants in Ireland.","authors":"Robert Thomas Joyce, Lisa K McCarthy, Colm Patrick Finbarr ODonnell","doi":"10.1136/archdischild-2025-328624","DOIUrl":"https://doi.org/10.1136/archdischild-2025-328624","url":null,"abstract":"","PeriodicalId":8177,"journal":{"name":"Archives of Disease in Childhood - Fetal and Neonatal Edition","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143727648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Facilitators and barriers to the practice of neonatal family integrated care from the perspective of healthcare professionals: a systematic review. 从医疗保健专业人员的角度来看,新生儿家庭综合护理的促进因素和障碍:系统回顾。
IF 3.9 2区 医学
Archives of Disease in Childhood - Fetal and Neonatal Edition Pub Date : 2025-03-12 DOI: 10.1136/archdischild-2024-327770
Nadia Leake, Sarah Edney, Nicholas Embleton, Janet Berrington, Judith Rankin
{"title":"Facilitators and barriers to the practice of neonatal family integrated care from the perspective of healthcare professionals: a systematic review.","authors":"Nadia Leake, Sarah Edney, Nicholas Embleton, Janet Berrington, Judith Rankin","doi":"10.1136/archdischild-2024-327770","DOIUrl":"https://doi.org/10.1136/archdischild-2024-327770","url":null,"abstract":"<p><strong>Objective: </strong>To conduct a systematic review of barriers and facilitators to the practice of neonatal Family Integrated Care (FICare) from the perspective of healthcare professionals (HCPs).</p><p><strong>Design: </strong>A systematic search strategy was developed to identify qualitative studies exploring neonatal HCPs' views of any of the principles of FICare. Six literature databases (CINAHL, (Cumulated Index in Nursing and Allied Health Literature) Embase, Medline, PsycINFO, Scopus, Web of Science) were searched using the terms Healthcare Professionals, Neonatal, Environment, FICare, Education, Well-being, Culture, Partnership and Empowerment. Studies meeting the inclusion criteria were thematically analysed.</p><p><strong>Results: </strong>11032 titles and abstracts and 85 full-text papers were screened. Thirty-seven studies met the inclusion criteria and reported interviews with 1243 HCPs, predominantly nurses. Three themes were synthesised in relation to barriers and facilitators: (1) 'advocacy and acknowledgement', whereby HCPs are expected to advocate for the emotional and mental health of the whole family, not solely the baby's needs; (2) 'belief and behaviour', whereby the degree to which FICare is practised is dependent on HCPs' belief in its benefits in relation to other activities; (3) 'conditions and consistency', whereby a lack of space, resources, policy and consistent practice of FICare created apathy and contradictory approaches to care.</p><p><strong>Conclusion: </strong>Although HCPs see value in FICare, successful implementation is multifactorial and requires the expectation to deliver FICare to be aligned with resourcing at the hospital, team and individual levels. Shifting the practice paradigm to FICare remains challenging for some HCPs. Greater understanding of HCPs' views on barriers, facilitators and how FICare practice impacts individuals is required.</p>","PeriodicalId":8177,"journal":{"name":"Archives of Disease in Childhood - Fetal and Neonatal Edition","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Azithromycin for eradication of Ureaplasma and prevention of bronchopulmonary dysplasia in preterm infants: a meta-analysis. 阿奇霉素用于根除脲原体和预防早产儿支气管肺发育不良:一项荟萃分析。
IF 3.9 2区 医学
Archives of Disease in Childhood - Fetal and Neonatal Edition Pub Date : 2025-03-05 DOI: 10.1136/archdischild-2024-328220
Zhe Chen, Zhimei Jiang, Dan Liu, Yan Wen, Linan Zeng, Liang Huang, Jing Shi, Lingli Zhang
{"title":"Azithromycin for eradication of <i>Ureaplasma</i> and prevention of bronchopulmonary dysplasia in preterm infants: a meta-analysis.","authors":"Zhe Chen, Zhimei Jiang, Dan Liu, Yan Wen, Linan Zeng, Liang Huang, Jing Shi, Lingli Zhang","doi":"10.1136/archdischild-2024-328220","DOIUrl":"https://doi.org/10.1136/archdischild-2024-328220","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the efficacy and safety of azithromycin in eradicating <i>Ureaplasma</i> and preventing bronchopulmonary dysplasia (BPD) in preterm infants.</p><p><strong>Design: </strong>Six literature databases and three clinical trial registration platforms were searched for studies up to 22 July 2024. The meta-analysis was performed using RevMan V.5.3.</p><p><strong>Results: </strong>A total of 1723 preterm infants from 10 randomised controlled trials and 3 case series were included. In all preterm infants, azithromycin significantly improved <i>Ureaplasma</i> clearance (relative risk (RR)=1.47, 95% CI 1.17 to 1.85) and reduced the duration of mechanical ventilation (mean difference (MD)=-2.16, 95% CI -2.65 to -1.68), duration of supplemental oxygen (MD=-5.46, 95% CI -6.65 to -4.37) and length of stay (MD=-4.98, 95% CI -7.19 to -2.76) compared with placebo; however, there was no significant reduction in BPD, BPD-death or mortality, with low quality of evidence. In <i>Ureaplasma</i>-positive preterm infants, azithromycin significantly reduced BPD-death (RR=0.83, 95% CI 0.70 to 0.99) and mechanical ventilation (MD=-2.20, 95% CI -2.72 to -1.69), compared with placebo, and significantly increased <i>Ureaplasma</i> clearance rate. Additionally, compared with erythromycin, azithromycin reduced BPD, without a statistically significant difference. Compared with placebo, azithromycin showed no statistically significant differences in the incidence of necrotising enterocolitis, retinopathy, intraventricular haemorrhage, etc. CONCLUSIONS: Low-quality evidence indicated prophylactic use of azithromycin could reduce the incidence of BPD-death and the duration of mechanical ventilation in <i>Ureaplasma</i>-positive preterm infants. However, such benefits were not observed in all preterm infants. Meanwhile, azithromycin was found to be safe for administration in preterm infants.</p><p><strong>Prospero registration number: </strong>CRD42024585836.</p>","PeriodicalId":8177,"journal":{"name":"Archives of Disease in Childhood - Fetal and Neonatal Edition","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143565866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A novel human milk fortifier supports adequate growth in very low birth weight infants: a non-inferiority randomised controlled trial. 一种新的人乳强化剂支持极低出生体重婴儿的充分生长:一项非劣效性随机对照试验。
IF 3.9 2区 医学
Archives of Disease in Childhood - Fetal and Neonatal Edition Pub Date : 2025-03-04 DOI: 10.1136/archdischild-2024-327282
Jean-Charles Picaud, Peter Robert Reynolds, Paul Clarke, Edith van den Hooven, Mirjam M van Weissenbruch, Richard A van Lingen, Annemiek Goedhart, Akke Botma, Ralf Boettger, Elke van Westering-Kroon, Christoph Fusch, J M Hascoet
{"title":"A novel human milk fortifier supports adequate growth in very low birth weight infants: a non-inferiority randomised controlled trial.","authors":"Jean-Charles Picaud, Peter Robert Reynolds, Paul Clarke, Edith van den Hooven, Mirjam M van Weissenbruch, Richard A van Lingen, Annemiek Goedhart, Akke Botma, Ralf Boettger, Elke van Westering-Kroon, Christoph Fusch, J M Hascoet","doi":"10.1136/archdischild-2024-327282","DOIUrl":"https://doi.org/10.1136/archdischild-2024-327282","url":null,"abstract":"<p><strong>Objective: </strong>To compare growth, tolerance and safety parameters in very preterm infants receiving human milk (HM) fortified with a multicomponent cow's milk-based HM fortifier (HMF; control) versus a novel HMF-containing lipids (including docosahexaenoic acid and arachidonic acid), higher protein and lower carbohydrate levels (test). Our hypothesis was that weight growth velocity in the test group would be non-inferior to that in the control group.</p><p><strong>Design: </strong>Double-blind, randomised controlled trial.</p><p><strong>Setting: </strong>Nine European neonatal intensive care units.</p><p><strong>Patients: </strong>HM-fed infants born at <32-week gestational age.</p><p><strong>Interventions: </strong>Fortification of HM with Test or Control HMF for a minimum of 21 days.</p><p><strong>Primary outcome: </strong>Weight growth velocity between baseline and intervention day 21.</p><p><strong>Results: </strong>From March 2018 to July 2020, 102 and 103 infants were enrolled in the test and control groups, respectively. Weight growth velocity during the first 21 days in the test group (mean 18.4 g/kg/day) was non-inferior to that of controls (mean 18.5 g/kg/day), with a difference in estimated means of -0.175 g/kg/day (90% CI -1.34 to +0.99 g/kg/day; per-protocol population). No significant differences between groups were observed for gain in length, head circumference or anthropometric Z-scores. Rates of digestive intolerance, stool frequency and consistency were comparable. No significant differences were reported in common neonatal morbidities including necrotising enterocolitis (test: 2.9%, control: 6.9%, mean difference -4.0% (95% CI -11.1% to 2.2%); all subjects treated population).</p><p><strong>Conclusions: </strong>Use of the novel HMF containing lipids, higher protein and lower carbohydrate levels supports adequate postnatal growth and appears safe and well tolerated in very preterm infants.</p><p><strong>Trial registration number: </strong>NCT03315221.</p>","PeriodicalId":8177,"journal":{"name":"Archives of Disease in Childhood - Fetal and Neonatal Edition","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143555700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Minimisation of blood sampling losses in preterm neonates: a systematic review and meta-analysis. 最大限度地减少早产儿的血样损失:一项系统回顾和荟萃分析。
IF 3.9 2区 医学
Archives of Disease in Childhood - Fetal and Neonatal Edition Pub Date : 2025-03-04 DOI: 10.1136/archdischild-2024-328337
Prathamesh Khedkar, Abhishek Srinivas, Haribalakrishna Balasubramanian, Mayuri Bhanushali, Anitha Ananthan, Diwakar Mohan, Nandkishore Kabra, Shripada C Rao, Sanjay K Patole
{"title":"Minimisation of blood sampling losses in preterm neonates: a systematic review and meta-analysis.","authors":"Prathamesh Khedkar, Abhishek Srinivas, Haribalakrishna Balasubramanian, Mayuri Bhanushali, Anitha Ananthan, Diwakar Mohan, Nandkishore Kabra, Shripada C Rao, Sanjay K Patole","doi":"10.1136/archdischild-2024-328337","DOIUrl":"https://doi.org/10.1136/archdischild-2024-328337","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the effect of minimising blood sampling losses on red blood cell (RBC) transfusion-related outcomes in preterm infants <37 weeks' gestation.</p><p><strong>Study design: </strong>We searched PubMed, Embase, Web of Science and Google Scholar from inception to October 2024 for studies that evaluated sampling stewardship practices (SSP) in preterm infants during initial hospitalisation. Two authors independently screened articles that evaluated one or more sampling approaches to minimise blood loss or non-invasive methods to avoid sampling losses. Meta-analysis was conducted using a random effects model.</p><p><strong>Results: </strong>Eighteen studies (4 randomised controlled trials (RCTs) and 14 non-randomised studies) were included. Five studies used umbilical cord blood sampling, four used protocol-based sampling and two used retransfusion of sampled blood back to the infant as an SSP. Sampling care bundles were used in seven studies. Meta-analysis showed that SSP reduced early RBC transfusion rates (RCTs: Relative risk(RR) =0.50, 95% CI 0.36, 0.68; non-RCTs: RR=0.78, 95% CI 0.69, 0.90), the average number of transfusions per infant (RCTs: mean difference=-0.4 transfusions, 95% CI -0.68, -0.05; non-RCTs: standardised mean difference=-0.40, 95% CI -0.55, -0.25) and the rates of multiple transfusions (non-RCTs: RR=0.51, 95% CI 0.42, 0.62). There were no significant effects on mortality and other morbidities. Certainty of evidence was high for transfusion-related outcomes and moderate for other outcomes.</p><p><strong>Conclusion: </strong>SSPs are associated with a significant reduction in RBC transfusion rates among very and extremely preterm infants. Large RCTs are required to assess the effects of SSP on other important outcomes.</p><p><strong>Prospero registration number: </strong>CRD42024539665.</p>","PeriodicalId":8177,"journal":{"name":"Archives of Disease in Childhood - Fetal and Neonatal Edition","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143555701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcomes of extremely preterm infants who participated in a randomised trial of dopamine for treatment of hypotension (the HIP trial) at 2 years corrected age. 在矫正年龄2岁时参加多巴胺治疗低血压的随机试验(HIP试验)的极早产儿的结果。
IF 3.9 2区 医学
Archives of Disease in Childhood - Fetal and Neonatal Edition Pub Date : 2025-03-04 DOI: 10.1136/archdischild-2024-327894
Neil Marlow, Keith J Barrington, Colm Patrick Finbarr ODonnell, Jan Miletin, Gunnar Naulaers, Po-Yin Cheung, John David Corcoran, Afif El-Khuffash, Geraldine B Boylan, Vicki Livingstone, Gerard Pons, Zbyněk Straňák, David Van Laere, Jozef Macko, Hana Wiedermannova, Eugene M Dempsey
{"title":"Outcomes of extremely preterm infants who participated in a randomised trial of dopamine for treatment of hypotension (the HIP trial) at 2 years corrected age.","authors":"Neil Marlow, Keith J Barrington, Colm Patrick Finbarr ODonnell, Jan Miletin, Gunnar Naulaers, Po-Yin Cheung, John David Corcoran, Afif El-Khuffash, Geraldine B Boylan, Vicki Livingstone, Gerard Pons, Zbyněk Straňák, David Van Laere, Jozef Macko, Hana Wiedermannova, Eugene M Dempsey","doi":"10.1136/archdischild-2024-327894","DOIUrl":"10.1136/archdischild-2024-327894","url":null,"abstract":"<p><strong>Objective: </strong>To determine survival and neurodevelopmental outcomes in the Hypotension in Preterm (HIP) trial.</p><p><strong>Design: </strong>Prospective follow-up of infants enrolled in randomised controlled trial.</p><p><strong>Participants: </strong>58 infants born before 28 weeks of gestation with low mean arterial blood pressure.</p><p><strong>Intervention: </strong>Random allocation to treatment of low blood pressure values with infusion of dopamine or placebo.</p><p><strong>Primary outcome: </strong>Survival without neurodevelopmental impairment to 24 months corrected age (CA).</p><p><strong>Results: </strong>The HIP trial stopped early due to logistic and recruitment difficulties. Outcomes were determined for 55 infants (27 in the dopamine group and 28 in the placebo group) at 24 months CA. Survival without impairment was present in 13 (48%) infants in the dopamine group and 7 (25%) infants in the placebo group (OR 2.79 (95% CI 0.89, 8.72); p=0.078). The components of the primary outcome were similarly distributed between the two arms. Mean Bayley composite scores and the frequency of somatic impairments did not differ significantly between groups but infants were shorter and lighter at 2 years of age after dopamine administration.</p><p><strong>Conclusion: </strong>In this placebo-controlled trial of the treatment of hypotension in extremely preterm infants, dopamine administration did not increase survival without impairment at 2 years CA. However, the study was not sufficiently powered and a clinically important effect cannot be excluded. The role of inotropic medication in facilitating good outcomes requires further study.</p>","PeriodicalId":8177,"journal":{"name":"Archives of Disease in Childhood - Fetal and Neonatal Edition","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142998936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Improving outcomes for very preterm babies in England: does place of birth matter? Findings from OPTI-PREM, a national cohort study. 改善英国早产儿的预后:出生地重要吗?OPTI-PREM是一项全国性队列研究。
IF 3.9 2区 医学
Archives of Disease in Childhood - Fetal and Neonatal Edition Pub Date : 2025-03-03 DOI: 10.1136/archdischild-2024-327474
Thillagavathie Pillay, Sarah E Seaton, Miaoqing Yang, Vasiliki Bountziouka, Victor Banda, Helen Campbell, Kelvin Dawson, Bradley N Manktelow, Elizabeth S Draper, Neena Modi, Elaine M Boyle, Oliver Rivero-Arias
{"title":"Improving outcomes for very preterm babies in England: does place of birth matter? Findings from OPTI-PREM, a national cohort study.","authors":"Thillagavathie Pillay, Sarah E Seaton, Miaoqing Yang, Vasiliki Bountziouka, Victor Banda, Helen Campbell, Kelvin Dawson, Bradley N Manktelow, Elizabeth S Draper, Neena Modi, Elaine M Boyle, Oliver Rivero-Arias","doi":"10.1136/archdischild-2024-327474","DOIUrl":"10.1136/archdischild-2024-327474","url":null,"abstract":"<p><strong>Objective: </strong>Babies born between 27<sup>+0</sup> and 31<sup>+6</sup> weeks of gestation contribute substantially towards infant mortality and morbidity. In England, their care is delivered in maternity services colocated with highly specialised neonatal intensive care units (NICU) or less specialised local neonatal units (LNU). We investigated whether birth setting offered survival and/or morbidity advantages to inform National Health Service delivery.</p><p><strong>Design: </strong>Retrospective national cohort study.</p><p><strong>Setting: </strong>LNU, NICU, England.</p><p><strong>Patients: </strong>UK National Neonatal Research Database whole population data for births between 27<sup>+0</sup> and 31<sup>+6</sup> weeks of gestation, discharged from/died within neonatal units between 1 January 2014 and 31 December 2018. We linked baby-level data to mortality information from the Office for National Statistics.</p><p><strong>Outcome measures: </strong>Death during neonatal care, up to 1 year (infant mortality), surgically treated necrotising enterocolitis, retinopathy of prematurity, severe brain injury (SBI), bronchopulmonary dysplasia.</p><p><strong>Intervention: </strong>Birth in NICU versus LNU setting. We used an instrumental variable (maternal excess travel time between the nearest NICU and LNU) estimation approach to determine treatment effect.</p><p><strong>Results: </strong>Of 18 847 babies (NICU: 10 379; LNU: 8468), 574 died in NICU/LNU care, and 121 postdischarge (infant mortality 3.7%). We found no effect of birth setting on neonatal or infant mortality. Significantly more babies born into LNU settings experienced SBI (mean difference -1.1% (99% CI -2.2% to -0.1%)). This was attenuated after excluding births at 27 weeks, and early postnatal transfers.</p><p><strong>Conclusions: </strong>In England, LNU teams should use clinical judgement, risk assessing benefits of transfer versus risk of SBI for preterm births at 27 weeks of gestation. 28 weeks of gestation is a safe threshold for preterm birth in either NICU/LNU settings.</p><p><strong>Trial registration number: </strong>NCT02994849/ISRCTN74230187.</p>","PeriodicalId":8177,"journal":{"name":"Archives of Disease in Childhood - Fetal and Neonatal Edition","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142891504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Success and safety of neonatal endotracheal tube exchanges: a NEAR4NEOS multicentre retrospective cohort study. 新生儿气管插管置换的成功和安全性:一项NEAR4NEOS多中心回顾性队列研究
IF 3.9 2区 医学
Archives of Disease in Childhood - Fetal and Neonatal Edition Pub Date : 2025-02-26 DOI: 10.1136/archdischild-2024-328287
Kathleen Miller, Nicole Pouppirt, Paul Wildenhain, Ayman Abou Mehrem, Ivana Brajkovic, Cassandra DeMartino, Kristen Glass, Kate Alison Hodgson, Philipp Jung, Ahmed Moussa, Mihai Puia-Dumitrescu, Binhuey Quek, Jennifer Rumpel, Rebecca Shay, David Tingay, Michelle D Tyler, Jennifer Unrau, Michael Wagner, Justine Shults, Akira Nishisaki, Elizabeth E Foglia, Heidi M Herrick
{"title":"Success and safety of neonatal endotracheal tube exchanges: a NEAR4NEOS multicentre retrospective cohort study.","authors":"Kathleen Miller, Nicole Pouppirt, Paul Wildenhain, Ayman Abou Mehrem, Ivana Brajkovic, Cassandra DeMartino, Kristen Glass, Kate Alison Hodgson, Philipp Jung, Ahmed Moussa, Mihai Puia-Dumitrescu, Binhuey Quek, Jennifer Rumpel, Rebecca Shay, David Tingay, Michelle D Tyler, Jennifer Unrau, Michael Wagner, Justine Shults, Akira Nishisaki, Elizabeth E Foglia, Heidi M Herrick","doi":"10.1136/archdischild-2024-328287","DOIUrl":"10.1136/archdischild-2024-328287","url":null,"abstract":"<p><strong>Objectives: </strong>To compare success and safety of endotracheal tube (ETT) exchanges with primary intubations and identify factors associated with ETT exchange outcomes.</p><p><strong>Design: </strong>Retrospective observational study of prospectively collected National Emergency Airway Registry for Neonates data. ETT exchanges are the placement of a new ETT when one is already in place, whereas primary intubations do not have a pre-existing ETT. The primary outcome was first-attempt success. Secondary outcomes included number of attempts, adverse tracheal intubation-associated events (TIAEs), severe TIAEs, desaturation and bradycardia. Descriptive statistics compared characteristics for ETT exchanges and primary intubations. Univariable and multivariable analyses compared primary and secondary outcomes and identified factors independently associated with ETT exchange outcomes.</p><p><strong>Results: </strong>A total of 1572 ETT exchanges and 9999 primary intubations across 21 sites were included from October 2014 to September 2022. ETT exchanges represented 2.3%-31.2% (mean 13.6%) of intubations across sites. Patient, provider and practice characteristics varied significantly between ETT exchanges and primary intubations. In univariable analyses, ETT exchanges were associated with higher first-attempt success (70.5% vs 53.6%; p<0.001) and fewer safety events. In multivariable analyses, ETT exchanges were associated with an increased adjusted OR (aOR) of first-attempt success (1.71; 95% CI 1.57 to 1.86; p<0.001). ETT exchanges were associated with lower aOR of all safety outcomes except severe TIAEs. Factors independently associated with ETT exchange first-attempt success included video laryngoscopy and paralytic premedication.</p><p><strong>Conclusion: </strong>Compared with primary intubations, ETT exchanges were associated with higher first-attempt success and fewer safety events. Video laryngoscope and paralytic premedication were associated with improved ETT exchange outcomes.</p>","PeriodicalId":8177,"journal":{"name":"Archives of Disease in Childhood - Fetal and Neonatal Edition","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143373450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between maternal sociodemographic characteristics and exclusive mother's own milk feeding in preterm infants: a cohort study using data from the National Neonatal Research Database. 母亲社会人口学特征与早产儿纯母乳喂养之间的关系:一项使用国家新生儿研究数据库数据的队列研究。
IF 3.9 2区 医学
Archives of Disease in Childhood - Fetal and Neonatal Edition Pub Date : 2025-02-26 DOI: 10.1136/archdischild-2024-327990
Melissa-Sue Ryan, Lisa Szatkowski, Arrisonia Doubatty, Shalini Ojha
{"title":"Association between maternal sociodemographic characteristics and exclusive mother's own milk feeding in preterm infants: a cohort study using data from the National Neonatal Research Database.","authors":"Melissa-Sue Ryan, Lisa Szatkowski, Arrisonia Doubatty, Shalini Ojha","doi":"10.1136/archdischild-2024-327990","DOIUrl":"https://doi.org/10.1136/archdischild-2024-327990","url":null,"abstract":"<p><strong>Objective: </strong>To ascertain the sociodemographic and geographical determinants of exclusive and no mother's own milk (MOM) feeding for infants <34 weeks' gestational age (GA) in England and Wales.</p><p><strong>Study design: </strong>Retrospective cohort study using the National Neonatal Research Database (2016-2022). We calculated unadjusted and mutually adjusted ORs for exclusive and no MOM feeding throughout an infant's neonatal stay, by maternal age group, ethnicity and deprivation quintile. Neonatal Operational Delivery Network and unit were included as random effects, and the adjusted models included other potential confounders such as gestational age and mode of delivery.</p><p><strong>Results: </strong>Among the 90 730 infants, 11 962 (13.2%) were exclusively MOM fed, while 9018 (9.9%) never received MOM. The odds of exclusive MOM feeding increased with decreasing maternal social deprivation (OR for least deprived vs most deprived quintile 2.16, 95% CI 2.01 to 2.33), while the odds of no MOM decreased (OR 0.33, 95% CI 0.30 to 0.36). The odds of exclusive MOM feeding were lower for Asian/Asian-British mothers compared with white mothers (OR 0.88, 95% CI 0.82 to 0.95). The odds of never receiving MOM were lower for Black, Asian and mixed ethnicities compared with white mothers. Infants of mothers aged 26-35 years had the highest odds of exclusive MOM feeding. There was a geographical variation in feeding practices with a north-south divide in the prevalence of never receiving MOM. There was a significant variation in feeding practices between neonatal units.</p><p><strong>Conclusion: </strong>Provision of MOM to preterm infants in England and Wales is associated with maternal sociodemographic characteristics.</p>","PeriodicalId":8177,"journal":{"name":"Archives of Disease in Childhood - Fetal and Neonatal Edition","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143514490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Giant congenital melanocytic naevus in a neonate. 一名新生儿的巨大先天性黑素细胞痣。
IF 3.9 2区 医学
Archives of Disease in Childhood - Fetal and Neonatal Edition Pub Date : 2025-02-21 DOI: 10.1136/archdischild-2024-327502
Nisha Aggarwal, Michael O'Sullivan, Dipti Shankar, Habib Bhurawala, Girish Desphande
{"title":"Giant congenital melanocytic naevus in a neonate.","authors":"Nisha Aggarwal, Michael O'Sullivan, Dipti Shankar, Habib Bhurawala, Girish Desphande","doi":"10.1136/archdischild-2024-327502","DOIUrl":"10.1136/archdischild-2024-327502","url":null,"abstract":"","PeriodicalId":8177,"journal":{"name":"Archives of Disease in Childhood - Fetal and Neonatal Edition","volume":" ","pages":"226"},"PeriodicalIF":3.9,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141726725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信