Journal of epilepsy最新文献_第10页

Periodic Left Temporal Sharp Waves During Acute Psychosis 急性精神病时周期性左颞尖波

Journal of epilepsy Pub Date : 1998-03-01 DOI: 10.1016/S0896-6974(97)00142-4

Eun-Kyu Lee

引用次数: 1

Use of the QOLIE-31 in Routine Clinical Practice QOLIE-31在常规临床实践中的应用

Journal of epilepsy Pub Date : 1998-01-01 DOI: 10.1016/S0896-6974(97)00110-2

Amy Nicole Grudzinski , Zafar Hakim , Stephen Joel Coons , David M Labiner

{"title":"Use of the QOLIE-31 in Routine Clinical Practice","authors":"Amy Nicole Grudzinski , Zafar Hakim , Stephen Joel Coons , David M Labiner","doi":"10.1016/S0896-6974(97)00110-2","DOIUrl":"10.1016/S0896-6974(97)00110-2","url":null,"abstract":"<div><p>The most important outcome of medical care may be the patient’s perception of his or her functioning and well-being, or quality of life. However, patient-reported quality of life is not often routinely and/or adequately assessed. This study examined the usefulness of health-related quality of life (HRQoL) information in predicting patient-reported health status when compared with information routinely obtained in a physician–patient interaction. A survey instrument was administered to 40 patients immediately prior to a scheduled epilepsy clinic visit. The instrument included the 31-item Quality of Life in Epilepsy Inventory (QOLIE-31) and 21 additional items that assessed, among other things, information routinely obtained in a physician–patient interaction regarding adverse drug effects and seizure frequency. Regression analysis revealed that information regarding seizure frequency and adverse drug effects provided little insight into patients’ self-perceived health status. Only 11.25% of the variance in patients’ self-reported health status was explained by variations in these traditional measures. The addition of QOLIE-derived data to traditional information significantly improved the ability to predict patients’ self-reported health status. The results of this study indicate that the administration of an HRQoL instrument in routine clinical practice offers additional insight into patients’ self-perceived health status. Furthermore, the study indicated that this additional information can be collected in a reasonable amount of time.</p></div>","PeriodicalId":81656,"journal":{"name":"Journal of epilepsy","volume":"11 1","pages":"Pages 34-47"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0896-6974(97)00110-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"56292035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12

Evolution and Localization of Postictal Blood Flow Changes in Partial Seizures Demonstrated by SPECT: Use of Quantitative Difference Images SPECT显示部分癫痫发作后血流变化的演变和定位:定量差分图像的使用

Journal of epilepsy Pub Date : 1998-01-01 DOI: 10.1016/S0896-6974(97)00109-6

Marianna V Spanaki , Susan S Spencer , Gary Wisniewski , John MacMullan , John Seibyl , I.George Zubal

{"title":"Evolution and Localization of Postictal Blood Flow Changes in Partial Seizures Demonstrated by SPECT: Use of Quantitative Difference Images","authors":"Marianna V Spanaki , Susan S Spencer , Gary Wisniewski , John MacMullan , John Seibyl , I.George Zubal","doi":"10.1016/S0896-6974(97)00109-6","DOIUrl":"10.1016/S0896-6974(97)00109-6","url":null,"abstract":"<div><p>Ictal single photon emission computed tomography (SPECT) is a sensitive means of seizure localization in partial epilepsy. The purpose of this study is to enhance the diagnostic yield of postictal SPECT for epilepsy and to overcome the difficulties in its conventional interpretation. We developed a method for coregistration, normalization, and subtraction of interictal from ictal SPECT to reveal positive difference images (and ictal from interictal to reveal negative difference images) of cerebral blood flow (CBF) during seizures. This method also allows quantification of regions of greatest percent increase and decrease, normalized to seizure duration. We studied 12 patients who had confirmed epileptogenic regions by surgery and pathology (seven temporal, five extratemporal). In all 12 patients, with either early (during ictus) or late injection (after seizure termination), the difference images showed increases or decreases respectively in blood flow consistent with the epileptogenic region. We highlight the localizing value of the negative difference change in perfusion (state of hypoperfusion) that persists for up to 100 seconds after seizure termination and corresponds to the epileptogenic region. Application of this technique for the quantification of perfusion changes during seizure or immediately after seizure cessation enhances the diagnostic yield of SPECT in both temporal and extratemporal epilepsy.</p></div>","PeriodicalId":81656,"journal":{"name":"Journal of epilepsy","volume":"11 1","pages":"Pages 25-33"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0896-6974(97)00109-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"56292014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 24

Seizure Etiologies in a Veterans’ Affairs Medical Center Population 退伍军人事务医疗中心人群的癫痫病因

Journal of epilepsy Pub Date : 1998-01-01 DOI: 10.1016/S0896-6974(97)00108-4

Alan B Ettinger , Caroline V Gatewood , Aliasgar Dhoon , George C Newman , Deborah M Weisbrot , Lina Jandorf , Orrin Devinsky

引用次数: 0

Diagnostic Value of EEG Analysis of Epileptic Focus in Mesial Temporal Lobe Epilepsy (MTLE) 中颞叶癫痫(MTLE)癫痫灶脑电图分析的诊断价值

Journal of epilepsy Pub Date : 1998-01-01 DOI: 10.1016/S0896-6974(97)00104-7

Harumi Yoshinaga , Shigeru Ohno , Tomoyuki Nakahori , Eiji Oka , Shunsuke Ohtahara , Akio Tanaka , Keiichi Miyamoto

{"title":"Diagnostic Value of EEG Analysis of Epileptic Focus in Mesial Temporal Lobe Epilepsy (MTLE)","authors":"Harumi Yoshinaga , Shigeru Ohno , Tomoyuki Nakahori , Eiji Oka , Shunsuke Ohtahara , Akio Tanaka , Keiichi Miyamoto","doi":"10.1016/S0896-6974(97)00104-7","DOIUrl":"10.1016/S0896-6974(97)00104-7","url":null,"abstract":"<div><p>For precise identification of an epileptic focus in mesial temporal lobe epilepsy (MTLE), various techniques, including neuroimaging, are employed. We performed topographic and spike dipole analyses to investigate the correlation between surface electroencephalogram (EEG) and the location of the lesion in 10 patients with MTLE. Six patients with interictal epileptic spikes on EEG were analyzed by the dipole localization method using CDT 1000 (Central Electronics Company, Tokyo). The location of the spike dipoles were compared with the location of abnormal lesions revealed by magnetic resonance imaging (MRI). In all 10 cases, EEG topography was also performed to determine an abnormal lesion from the EEG background activity. In six cases, spike dipoles were located at the mesial temporal lobe, which corresponded to the MRI lesion. In seven of the 10 cases, EEG topography revealed the deviation of the delta band to one side in the frontal to anterior temporal area. In these seven cases, the laterality of the delta band deviation coincided with the site of the MRI abnormality. In one case, a topographic abnormality was provoked after sleep deprivation. We conclude that EEG analysis combined with MRI is useful for the evaluation of the epileptic focus in MTLE. Topographic analysis of basic EEG was considered to be beneficial especially in MTLE, in which epileptic spikes were rare.</p></div>","PeriodicalId":81656,"journal":{"name":"Journal of epilepsy","volume":"11 1","pages":"Pages 1-9"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0896-6974(97)00104-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"56291532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Symptoms of Psychiatric Disturbance in Epilepsy 癫痫患者精神障碍的症状

Journal of epilepsy Pub Date : 1998-01-01 DOI: 10.1016/S0896-6974(97)00105-9

Alan B Ettinger , Deborah M Weisbrot , Lauren B Krupp , Lina Jandorf , Elizabeth Gaudino , Joyce Cramer

{"title":"Symptoms of Psychiatric Disturbance in Epilepsy","authors":"Alan B Ettinger , Deborah M Weisbrot , Lauren B Krupp , Lina Jandorf , Elizabeth Gaudino , Joyce Cramer","doi":"10.1016/S0896-6974(97)00105-9","DOIUrl":"10.1016/S0896-6974(97)00105-9","url":null,"abstract":"<div><p><span>To assess the severity and nature of symptoms of psychiatric distress among tertiary center epilepsy patients, we administered the Brief Symptom Inventory (BSI) and Center for Epidemiologic Studies-Depression Scale (CES-D) to adult patients evaluated at our tertiary center who were diagnosed with Epilepsy (EPI; </span><em>n</em><span> = 37), or Chronic Lyme Disease (CLD, </span><em>n</em> = 38). We compared results in these groups to published studies in normal healthy adults (NHA) and psychiatric outpatients (Psych). Mean global BSI and CES-D scores were both markedly elevated in the EPI and CLD groups compared to NHA but less than Psych. Subscores of the BSI varied among the EPI and CLD groups with higher obsessive compulsive symptoms among CLD patients (<em>p</em> = .014), higher paranoid symptoms in the EPI group (<em>p</em><span> = .021), and a trend toward higher somatization subscores in the CLD group (</span><em>p</em> = .054). Symptoms of psychiatric distress including depression are common among tertiary epilepsy center patients as well as patients with CLD.</p></div>","PeriodicalId":81656,"journal":{"name":"Journal of epilepsy","volume":"11 1","pages":"Pages 10-14"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0896-6974(97)00105-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"56291621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 16

Expectations and Life Changes Associated with Surgery for Intractable Epilepsy 与顽固性癫痫手术相关的期望和生活变化

Journal of epilepsy Pub Date : 1998-01-01 DOI: 10.1016/S0896-6974(97)00111-4

Ingrid Wheelock

{"title":"Expectations and Life Changes Associated with Surgery for Intractable Epilepsy","authors":"Ingrid Wheelock","doi":"10.1016/S0896-6974(97)00111-4","DOIUrl":"10.1016/S0896-6974(97)00111-4","url":null,"abstract":"<div><p>This longitudinal study examined the impact of epilepsy surgery on 32 patients and 17 of their significant others. Subjects were assessed prior to surgery and 1 year postsurgery with a semistructured interview that assessed subjects’ presurgery expectations and postsurgery reports of relationship changes, positive life changes, and negative life changes associated with seizure elimination and reduction. Prior to surgery, subjects anticipated that patients would experience a number of changes, including more friendships (49%), greater independence (47%), and the ability to engage in activities such as driving (71%) and working (65%). Most subjects (61%) did not anticipate that the patient would experience any difficulties associated with seizure elimination or reduction. Following surgery, subjects in the seizure-free group were more likely than subjects in the continued seizures group to report relationship changes and positive life changes. Some positive changes, such as reduction in anxiety and fatigue, that were reported at follow-up had not been predicted prior to surgery. It is possible that these benefits of seizure elimination become apparent only once the symptoms are eliminated. Few subjects reported negative changes associated with seizure elimination. The clinical implications of these findings are presented.</p></div>","PeriodicalId":81656,"journal":{"name":"Journal of epilepsy","volume":"11 1","pages":"Pages 48-57"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0896-6974(97)00111-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"56292104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Long Latency Auditory Evoked Potentials in Nonlesional Partial Epilepsy 非病变性部分性癫痫的长潜伏期听觉诱发电位

Journal of epilepsy Pub Date : 1998-01-01 DOI: 10.1016/S0896-6974(97)00107-2

Miles E Drake Jr. , Steven J Weate , Jodie M Andrews , Janet E Bogner

{"title":"Long Latency Auditory Evoked Potentials in Nonlesional Partial Epilepsy","authors":"Miles E Drake Jr. , Steven J Weate , Jodie M Andrews , Janet E Bogner","doi":"10.1016/S0896-6974(97)00107-2","DOIUrl":"10.1016/S0896-6974(97)00107-2","url":null,"abstract":"<div><p><span><span>Event-related potentials have been occasionally investigated in epilepsy. We recorded slow vertex responses or long-latency auditory evoked potentials<span><span> (LLAEPs) to auditory stimuli in patients with complex partial and secondarily </span>generalized seizures. Fifty consecutive neurologically-normal patients with normal imaging studies and 50 controls were compared. Slow vertex response (SVR) recordings utilized monaural condensation clicks presented at 0.5 Hz and 100 dB sound pressure level (SPL) with 40 dB </span></span>contralateral<span> masking; filter bandpass was 1–50 Hz, analysis time was 500 mseconds, and 200 averages were recorded and replicated. Long-latency auditory evoked potentials were recorded from Fz and Cz to linked-ear and ipsilateral-ear reference. Long-latency auditory evoked potential latencies of N100 potentials were significantly prolonged in patients as compared to controls, while P180 and N200 were longer in latency among patients but did not achieve statistical significance. N100 and P180 were significantly prolonged in latency on the side of the electroencephalogram (EEG)-documented </span></span>epileptogenic focus in the seizure patients.</p><p>These findings support previous suggestions of frontal or temporal cortical origin for SVRs, and suggest that LLAEP components may be prolonged in latency on the side of an irritative focus. Long-latency auditory evoked potential latency prolongation or asymmetry may therefore assist in the noninvasive neurophysiologic assessment of epilepsy patients.</p></div>","PeriodicalId":81656,"journal":{"name":"Journal of epilepsy","volume":"11 1","pages":"Pages 15-19"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0896-6974(97)00107-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"56291808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

儿童神经问题，尼尔·戈登(编辑)。巴特沃斯-海涅曼，牛顿，马萨诸塞州(1993)，339，价格:$80.00

Journal of epilepsy Pub Date : 1997-11-01 DOI: 10.1016/S0896-6974(97)00101-1

M.D. James J. Riviello .Jr

引用次数: 0

An evaluation of the management of epilepsy by primary health care nurses in Chitungwiza, Zimbabwe 对津巴布韦奇通维扎初级卫生保健护士癫痫管理的评估

Journal of epilepsy Pub Date : 1997-11-01 DOI: 10.1016/S0896-6974(97)00069-8

Bola Adamolekun , Jens Mielke , Douglas Ball , Tendai Mundanda

{"title":"An evaluation of the management of epilepsy by primary health care nurses in Chitungwiza, Zimbabwe","authors":"Bola Adamolekun , Jens Mielke , Douglas Ball , Tendai Mundanda","doi":"10.1016/S0896-6974(97)00069-8","DOIUrl":"https://doi.org/10.1016/S0896-6974(97)00069-8","url":null,"abstract":"<div><p>In order to design an effective training program for nurses on the management of epilepsy in Zimbabwe, the drug management of epilepsy by community health nurses without prior training in epilepsy management was evaluated. Epilepsy patients in Chitungwiza, a high density suburb of Harare, were routinely managed at four health clinics run by nurses. The patients also attended a monthly epilepsy support group (ESG) program that provided them with vocational and social rehabilitative support. The drug therapy of all patients attending this support group program was evaluated by neurologists over a 2-year period. The specialist interventions required for drug therapy in patients with inadequate seizure control or drug side effects were noted. One-hundred and fourteen epilepsy patients (age range, 8–56 years, M:F = 1:1.2) were seen; 84.2% had generalized seizures; 40.3% of patients had been seizure free for at least 6 months; 71.9% of patients were on phenobarbitone, while 59.6% were on monotherapy. No drug intervention was required to ongoing drug therapy in 43% of patient consultations. The most important intervention in patients with inadequate seizure control was an increase in drug dose, required in 29% of consultations. Fifty-eight percent of serum drug level estimations in clinically indicated cases were below the therapeutic ranges. This tendency to subtherapeutic dosing with an antiepileptic drug (AED) among nurses suggested that a written AED drug therapy protocol specifying optimal maintenance doses and dose increment schedules may be beneficial to the community-based nursing management of epilepsy.</p></div>","PeriodicalId":81656,"journal":{"name":"Journal of epilepsy","volume":"10 6","pages":"Pages 294-297"},"PeriodicalIF":0.0,"publicationDate":"1997-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0896-6974(97)00069-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92059697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0