Archives of andrology最新文献_第6页

Increased total antioxidant capacity in seminal plasma of varicocele patients: a multivariate analysis. 精索静脉曲张患者精浆总抗氧化能力增加:一项多变量分析。

Archives of andrology Pub Date : 2007-01-01 DOI: 10.1080/01485010600840756

Antonio Mancini, Domenico Milardi, Antonio Bianchi, Roberto Festa, Andrea Silvestrini, Laura De Marinis, Alfredo Pontecorvi, Elisabetta Meucci

{"title":"Increased total antioxidant capacity in seminal plasma of varicocele patients: a multivariate analysis.","authors":"Antonio Mancini, Domenico Milardi, Antonio Bianchi, Roberto Festa, Andrea Silvestrini, Laura De Marinis, Alfredo Pontecorvi, Elisabetta Meucci","doi":"10.1080/01485010600840756","DOIUrl":"https://doi.org/10.1080/01485010600840756","url":null,"abstract":"To investigate seminal antioxidant systems and their correlation with hormonal pattern in varicocele patients, we studied 33 varicocele (VAR) patients (12 oligozoospermic, 21 normozoospermic) and 34 non-VARs (10 idiopathic oligozoospermic, 24 normozoospermic). Non-enzymatic total antioxidant capacity (TAC) was measured using H(2)O(2)-metamyoglobin, which generates the radical form, spectroscopically detectable, of the chromogen 2,2',-azinobis-3-ethylbenzothiazoline-6-sulphonate (ABTS): time till appearance (Lag) of ABTS*(-) signifies antioxidant concentration. Lag was significantly longer in VARs than controls suggesting ineffective utilization of antioxidants. A significant direct correlation (r = 0.65, p < 0.01) of Lag with sperm count was observed in non-VARs, while in VARs it was inverted, as well as with hematic FSH levels. A multivariate analysis including FSH, Lag, progressive spermatozoa, oligozoospermia and varicocele indicated a strong inverse correlation between FSH and motility (r(2) = 0.31, p > F = 0.0007), not modified by Lag (r(2) = 0.31, p > F = 0.002). Their inverse correlation with Lag may suggest that higher FSH levels, improving sperm antioxidant efficiency, counterbalance varicocele-induced dyspermia.","PeriodicalId":8143,"journal":{"name":"Archives of andrology","volume":"53 1","pages":"37-42"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/01485010600840756","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26207913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 17

Correlation of seminal parameters with serum lipid profile and sex hormones. 精液参数与血脂和性激素的相关性。

Archives of andrology Pub Date : 2007-01-01 DOI: 10.1080/01485010600888961

A Ergün, S K Köse, K Aydos, A Ata, A Avci

引用次数: 50

Varicocele-induced testicular dysfunction may be associated with disruption of blood-testis barrier. 精索静脉曲张引起的睾丸功能障碍可能与血睾丸屏障的破坏有关。

Archives of andrology Pub Date : 2007-01-01 DOI: 10.1080/01485010600822606

I T Koksal, Y Ishak, M Usta, A Danisman, E Guntekin, I C Bassorgun, A Ciftcioglu

{"title":"Varicocele-induced testicular dysfunction may be associated with disruption of blood-testis barrier.","authors":"I T Koksal, Y Ishak, M Usta, A Danisman, E Guntekin, I C Bassorgun, A Ciftcioglu","doi":"10.1080/01485010600822606","DOIUrl":"https://doi.org/10.1080/01485010600822606","url":null,"abstract":"The objective of this study was to examine E-cadherin and alpha-catenin expression at the junctions between adjacent Sertoli cells in testicular specimens from patients with varicocele in order to determine the presence of a possible link between blood-testis barrier and pathophysiology of varicocele. A total of 51 testicular biopsies were obtained from 28 infertile men with unilateral or bilateral varicocele. Twenty-three patients had bilateral and 5 had unilateral varicocele, Grade I varicocele was detected in 30 (59%), grade II in 15 (29%) and grade III in 6 (12%) patients. Abnormal expression of E-cadherin and alpha-catenin at the junctions between adjacent Sertoli cells was demonstrated in 100% and 90% of the patients with varicocele, respectively. In those with grade I-III varicocele, the mean E-cadherin and alpha-catenin expression were 7.6 +/- 11.4 and 39 +/- 36; 7.6 +/- 0.0 and 49 +/- 30; 8.3 +/- 9.3 and 58 +/- 33, respectively, but the difference was not significant. Reduced E-cadherin and alpha-catenin expression at the junctions between adjacent Sertoli cells may be associated with disruption of blood-testis barrier in varicocele.","PeriodicalId":8143,"journal":{"name":"Archives of andrology","volume":"53 1","pages":"43-8"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/01485010600822606","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26607182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 39

Combination of hypoosmotic swelling/eosin Y test for sperm membrane integrity evaluation: correlations with other sperm parameters to predict ICSI cycles. 结合低渗肿胀/伊红Y试验评价精子膜完整性:与其他精子参数预测ICSI周期的相关性

Archives of andrology Pub Date : 2007-01-01 DOI: 10.1080/01485010600888912

M Cincik, A R Ergur, L Tutuncu, M Muhcu, M Kilic, B Balaban, B Urman

{"title":"Combination of hypoosmotic swelling/eosin Y test for sperm membrane integrity evaluation: correlations with other sperm parameters to predict ICSI cycles.","authors":"M Cincik, A R Ergur, L Tutuncu, M Muhcu, M Kilic, B Balaban, B Urman","doi":"10.1080/01485010600888912","DOIUrl":"https://doi.org/10.1080/01485010600888912","url":null,"abstract":"The objective of our study was to evaluate the accuracy of the combination of hypoosmotic swelling (HOS) and eosin Y (Ey) exclusion tests to predict the ICSI cycles' outcome and its correlations with other sperm parameters. The functional and structural integrity of sperm membrane was evaluated with the combined HOS/Ey test in 95 ICSI cycles and the results were correlated with other sperm parameters, including concentration, motility, strict morphology, and total motile sperm count. The combined HOS/Ey test was evaluated for the prediction of the ICSI cycles' outcome parameters including fertilization, cleavage, and pregnancy rates. The HOS/Ey test presented significant relationships with concentration, motility, and strict morphology (p < 0,0001) but it couldn't predict the fertilization, cleavage, and pregnancy outcomes of ICSI cycles. The combined HOS/Ey test has strong correlations with motility and strict morphology parameters of sperm samples but is not sufficiently sensitive to estimate the outcome of ICSI cycles.","PeriodicalId":8143,"journal":{"name":"Archives of andrology","volume":"53 1","pages":"25-8"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/01485010600888912","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26207909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 25

Sperm survival: relationship to age-related sperm DNA integrity in infertile men. 精子存活:与不育男性年龄相关的精子DNA完整性的关系。

Archives of andrology Pub Date : 2007-01-01 DOI: 10.1080/01485010600908330

S I Moskovtsev, J Willis, J White, J B M Mullen

引用次数: 17

Citation analysis of five journals in andrology. 男科五种期刊引文分析。

Archives of andrology Pub Date : 2006-11-01 DOI: 10.1080/01485010600840764

H Yang, B-C Pan, J Chen

{"title":"Citation analysis of five journals in andrology.","authors":"H Yang, B-C Pan, J Chen","doi":"10.1080/01485010600840764","DOIUrl":"https://doi.org/10.1080/01485010600840764","url":null,"abstract":"Aim: To find out features in literature demand by researchers in the field of andrology and to offer advice on literature utilization and journal management.Methods: Five andrology journals indexed by Science Citation Index Expanded (SCI-E) (Andrologia, Archives of Andrology, Asian Journal of Andrology, International Journal of Andrology, and Journal of Andrology) were included in the study. Original articles, editorials, reviews, corrections and letters from these journals were analyzed with bibliometric method for document loading, citations, information absorbing ability, and geographical coverage.Results: The average number of references in each paper was 28.78. The main type of references was periodicals (94.32%), while books and other sources accounted for only 5.68%. Average Price index was 30.14%. The number of references in the first ranking 10 periodicals cited by the five journals made up 34.53% of the total references cited. Geographically, the five journals covered 6 continents with 42 countries or regions.Conclusion: Andrology journals have a wide coverage of literatures, which are related to reproductive medicine, urology, endocrinology and biochemistry. References in andrology journals are mainly periodicals and are relatively old. US, China and Japan lead the world in andrology researches for the number of papers published.","PeriodicalId":8143,"journal":{"name":"Archives of andrology","volume":"52 6","pages":"433-40"},"PeriodicalIF":0.0,"publicationDate":"2006-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/01485010600840764","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26316430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Expression of p57kip2 in germ cells and Leydig cells in human testis. p57kip2在人睾丸生殖细胞和间质细胞中的表达。

Archives of andrology Pub Date : 2006-11-01 DOI: 10.1080/01485010600822903

S T Kim, N C Park, Lee S H Yi, M C Gye

{"title":"Expression of p57kip2 in germ cells and Leydig cells in human testis.","authors":"S T Kim, N C Park, Lee S H Yi, M C Gye","doi":"10.1080/01485010600822903","DOIUrl":"https://doi.org/10.1080/01485010600822903","url":null,"abstract":"p57kip2, a KIP family cyclin-dependent kinase (Cdk) inhibitor, blocks the cell cycle by acting on multiple cyclin-Cdk complexes. To investigate the role of p57kip2 in human fertility, the expression of p57kip2 was investigated in testes from normal and obstructive azoospermic male patients who were positive for p57kip2 mRNA. In the seminiferous tubule, strong immunoreactivity of p57kip2 was found in nuclei of early spermatocytes, but not in the spermatogonia. The p57kip2 immunoreactivity in spermatocytes was markedly heterogeneous. Preleptotene spermatocytes showed strong p57kip2 immunoreactivity, but no visible signal was found in late pachytene spermatocytes. Nuclei of the elongating spermatids was also positive for p57kip2 immunoreactivity. Taken together, this suggests that p57kip2 may play a role in the regulation of meiotic progression of early spermatocytes and cell cycle arrest and differentiation of spermatids. p57kip2 immunoreactivity was found in the perinuclear region of the peritubular cells, but not in the Sertoli cells. In Leydig cells, moderate immunoreactivity of p57kip2 was largely found in the cytoplasm, suggesting the noble function of p57kip2 in the differentiation of adult Leydig cells.","PeriodicalId":8143,"journal":{"name":"Archives of andrology","volume":"52 6","pages":"463-9"},"PeriodicalIF":0.0,"publicationDate":"2006-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/01485010600822903","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26316435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Postpubertal testicular/epididymal epithelial thickness alterations in unilateral epididymal/vasal obstruction of prepubertal rats. 青春期前大鼠单侧附睾/血管梗阻的青春期后睾丸/附睾上皮厚度改变。

Archives of andrology Pub Date : 2006-11-01 DOI: 10.1080/01485010600840723

H Aktuğ, K Ozdedeli, B Altay, I Cüreklibatir, O Yilmaz, S Albay, K Ergin, M Turgut

引用次数: 1

Carbohydrate affinity chromatography indicates that arylsulfatase-A from capacitated boar sperm has mannose and N-acetylglucosamine/sialic acid residues. 碳水化合物亲和层析表明，从获能的野猪精子中提取的芳基硫酸酯酶a含有甘露糖和n -乙酰氨基葡萄糖/唾液酸残基。

Archives of andrology Pub Date : 2006-11-01 DOI: 10.1080/01485010600694690

Irma Jiménez, Reyna Fierro, Humberto González-Márquez, Guillermo Mendoza-Hernández, Salvador Romo, Miguel Betancourt

{"title":"Carbohydrate affinity chromatography indicates that arylsulfatase-A from capacitated boar sperm has mannose and N-acetylglucosamine/sialic acid residues.","authors":"Irma Jiménez, Reyna Fierro, Humberto González-Márquez, Guillermo Mendoza-Hernández, Salvador Romo, Miguel Betancourt","doi":"10.1080/01485010600694690","DOIUrl":"https://doi.org/10.1080/01485010600694690","url":null,"abstract":"Carbohydrate residues on membrane proteins from sperm are important in gamete interaction. In recent years, Arylsulfatase A (AS-A) has been acquiring an important role from the various putative gamete interaction responsibles in sperm. The aim of this study was to determine if the capacitated boar sperm Arylsulfatase-A (AS-A), contains D-mannose, N-acetylglucosamine and/or sialic acid residues by its purification using affinity chromatography with Concanavalia ensiformis Agglutinin(Con-A) or Wheat Germ Agglutinin (WGA) as ligands. Sperm samples were capacitated in TALP-HEPES medium. Protein extract was added to the affinity columns. Sequencing of retained proteins was done after SDS-PAGE. Total capacitated sperm proteins electrophoresis showed molecular masses between 14 kDa and 102 kDa. A major band of 68 kDa, and 2 minor bands of 52 kDa and 47 kDa were observed. They were AS-A, hyaluronidase and lactadherin, respectively. The Con-A-retained proteins (RP) pattern showed bands from 14 to 98 kDa. After sequencing and BLAST analysis, the 62 kDa band corresponded to Arylsulfatase-A. The WGA RP fraction showed bands from 14 to 100 kDa. The 65 kDa band corresponded to AS-A. This study showed that AS-A has mannose, N-acetylglucosamine and/or sialic acid residues as part of its glycosilation. In this study AS-A was isolated from boar capacitated sperm by affinity chromatography using separately Con-A and WGA, indicating that there are mannose, N-acetylglucosamine and/or sialic acid residues in its glycosilation. AS-A is a membrane protein of capacitated sperm. Further investigation is needed to fully characterize the glycosidic residues bore by AS-A and to determine its function.","PeriodicalId":8143,"journal":{"name":"Archives of andrology","volume":"52 6","pages":"455-62"},"PeriodicalIF":0.0,"publicationDate":"2006-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/01485010600694690","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26316433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Clinical, andrological and genetic characteristics of patients with congenital bilateral absence of vas deferens (CBAVD). 先天性双侧输精管缺失(CBAVD)患者的临床、男性学和遗传学特征。

Archives of andrology Pub Date : 2006-11-01 DOI: 10.1080/01485010600691993

H Samli, M M Samli, E Yilmaz, N Imirzalioglu

引用次数: 20