Correlation of seminal parameters with serum lipid profile and sex hormones.

A Ergün, S K Köse, K Aydos, A Ata, A Avci
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引用次数: 50

Abstract

The phospholipids and fatty acid composition of sperm are altered under the influence of serum lipids on impaired seminal parameters in infertile men. We studied the correlation of the serum lipid profile and sex hormone results of a group of infertile men with sperm characteristics of 18 infertile men. Semen samples were collected and analyzed. Serum fasted and post-meal glucose levels, insulin, total cholesterol, HDL, LDL, VLDL, triglyceride, FSH, LH, and testosterone measurements were performed. The increased serum VLDL, total triglyceride, and testosterone values were significantly correlated with decreased sperm motility. Serum FSH values were also inversely correlated with normal sperm morphology. The increased VLDL impaired seminal parameters; additionally, increased triglycerides may have deleterious effects on spermatogenesis. Deterioration is related with increased serum VLDL and triglyceride levels.

精液参数与血脂和性激素的相关性。
精子磷脂和脂肪酸组成在血清脂质对不育男性精液参数受损的影响下发生改变。我们研究了一组不育男性的血脂和性激素结果与18名不育男性精子特征的相关性。采集并分析精液样本。测定空腹和餐后血清葡萄糖水平、胰岛素、总胆固醇、HDL、LDL、VLDL、甘油三酯、FSH、LH和睾酮水平。血清VLDL、总甘油三酯和睾酮值升高与精子活力降低显著相关。血清FSH值也与正常精子形态呈负相关。VLDL升高使精液参数受损;此外,增加的甘油三酯可能对精子发生有有害影响。病情恶化与血清VLDL和甘油三酯水平升高有关。
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