Arab Journal of Urology最新文献

{"title":"A response to Nasrallah et al. \"Infection rates of trans-perineal versus trans-rectal prostate biopsy: A Middle Eastern tertiary center experience-Time for a change?\"","authors":"Minesh Patel, Joseph Norris","doi":"10.1080/20905998.2025.2585749","DOIUrl":"10.1080/20905998.2025.2585749","url":null,"abstract":"","PeriodicalId":8113,"journal":{"name":"Arab Journal of Urology","volume":"24 1","pages":"66-67"},"PeriodicalIF":1.2,"publicationDate":"2025-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12777907/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145931668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Double versus standard dose of tamsulosin with solifenacin for management of ureteral stent related symptoms.","authors":"Ahmad Hefnawy, Mohamed Ramadan, Hisham Arafa, Tarek Osman, Mohamed Saied","doi":"10.1080/20905998.2025.2561225","DOIUrl":"https://doi.org/10.1080/20905998.2025.2561225","url":null,"abstract":"<p><strong>Background: </strong>Ureteral stents are commonly used to ensure adequate drainage of the upper urinary tract in the presence, or anticipated occurrence, of ureteral obstruction. However, stent-related symptoms are frequent and represent a significant source of morbidity. Although several pharmacological treatment options are currently available, symptom relief remains often incomplete. In an effort to achieve better control of stent-related symptoms, we evaluated the efficacy of dose doubling in two commonly used drug combinations that have demonstrated symptomatic benefits in this context.</p><p><strong>Objective: </strong>To evaluate the efficacy of a double dose of solifenacin and tamsulosin compared to the standard dose of the same agents in alleviating stent-related symptoms.</p><p><strong>Patients and methods: </strong>A randomized clinical trial was conducted involving 64 Egyptian patients recruited from the outpatient clinic and inpatient services of the Urology Department at Ain Shams University Hospital over a six-month period.</p><p><strong>Results: </strong>After two weeks of treatment, the double dose of tamsulosin and solifenacin was significantly more effective in reducing stent-related symptoms compared to the standard dose. A statistically significant difference in symptom scores was observed between the double-dose and standard-dose groups. Side effects were more frequent in the double-dose group, with retrograde ejaculation and dry mouth occurring at significantly higher rates.</p><p><strong>Conclusion: </strong>The combination of tamsulosin and solifenacin is effective in alleviating stent-related symptoms. In patients who continue to experience symptoms despite standard-dose therapy, doubling the dose of both agents may offer additional symptomatic relief, albeit with a higher incidence of temporary and manageable side effects.</p>","PeriodicalId":8113,"journal":{"name":"Arab Journal of Urology","volume":"24 2","pages":"108-113"},"PeriodicalIF":1.2,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13045170/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147621519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The outcome of pre-renal transplant bladder cycling in patients with defunctionalized bladder.","authors":"M Esmat, Ahmed Higazy, Mohamed Shaker, Ahmed Radwan, Mohamed Kandil","doi":"10.1080/20905998.2025.2560262","DOIUrl":"https://doi.org/10.1080/20905998.2025.2560262","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the effectiveness of programmed bladder cycling (PBC) prior to transplantation in patients with defunctionalized bladders (DB).</p><p><strong>Methods: </strong>This prospective cohort study included RT candidates with DB. Eligible patients underwent pre-transplant PBC, and urodynamic parameters were assessed before and after the intervention. The primary outcome was the improvement in bladder capacity. Secondary outcomes included voiding parameters, and perioperative urological complications.</p><p><strong>Results: </strong>23 patients underwent PBC for a maximum of 6 months duration. Of these, 20 (86%) patients achieved the targeted bladder capacity of ≥ 250 ml. Median bladder capacity significantly increased from 147.5 mL (IQR 128.8-155) pre-PBC to 265 mL (IQR 253.8-286.3) post-PBC (<i>p</i> < 0.001). Median bladder compliance improved from 12 mL/cmH₂O (IQR 9-14) to 25 mL/cmH₂O (IQR 20.8-30) (<i>p</i> < 0.001). Post-RT, bladder capacity further increased to 314 mL (IQR 310-325) at 3 months and 376 mL (IQR 360-393.5) at 6 months (<i>p</i> < 0.001). Only one patient (5%) developed febrile UTI requiring readmission.</p><p><strong>Conclusion: </strong>PBC is a simple and effective outpatient intervention that significantly improves bladder capacity and compliance in patients with DB and probably decreases complications that may occur during and after renal transplantation.</p>","PeriodicalId":8113,"journal":{"name":"Arab Journal of Urology","volume":"24 2","pages":"149-154"},"PeriodicalIF":1.2,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13045188/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147621639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of pigtail suture stent vs conventional DJ stent in ureteral stent symptom occurrences: A systematic review and meta-analysis.","authors":"Krisna Adhitya Wilantara Yusuf, Ginanda Putra Siregar, Syah Mirsya Warli, Bungaran Sihombing, Dhirajaya Dharma Kadar, Yacobda H Sigumonrong, Ramlan Nasution, Fauriski Febrian Prapiska, Kharisma Prasetya Adhyatma, Dianita Halimah Harahap, Muhammad Haritsyah Warli","doi":"10.1080/20905998.2025.2550798","DOIUrl":"https://doi.org/10.1080/20905998.2025.2550798","url":null,"abstract":"<p><strong>Introduction: </strong>Pigtail suture stent (PSS) was introduced to reduce the occurrence of ureteral stent symptoms that often occur after placement of DJ stent for most endourology procedures. This study aims to conduct a review and meta-analysis to compare the occurrence of ureteral stent symptoms between PSS and conventional DJ stent using the validated Ureteral Stent Symptom Questionnaire (USSQ).</p><p><strong>Methods: </strong>Literature search was done under the PRISMA guidelines. Eligible studies were included, data were extracted, and pooled analyses were made according to each domain of the Ureteral Stent Symptom Questionnaire (USSQ), namely Urinary Index score, Pain Index score, General Health Index score, Work Performance Score, and Sexual Matters. Pooled effect estimates were generated as Mean difference and their 95%CI, statistical significance was defined with P-value < 0.05, and heterogeneity was examined using I² analyses. Sensitivity analyses were done to omit confounding.</p><p><strong>Results: </strong>A total of four eligible studies were identified and included in the meta-analysis. A total of 314 patients were included across two RCTs and two prospective cohort studies. Among the USSQ domain, Urinary index (MD = -10.11; 95% CI: -15.24, -4.98; <i>p</i> = 0.0001), pain index control (MD = -8.05; 95% CI: -15.63, -0.48; <i>p</i> = 0.04), and work performance (MD = -1.90; 95% CI: -2.34, -1.46; <i>p</i> < 0.00001) were found to be improved better in PSS compared to conventional DJ stent, while general health index and sexual matter were comparable. Sensitivity analyses were conducted, and no studies were omitted.</p><p><strong>Conclusion: </strong>Ureteral stent-related symptoms were significantly better in the PSS compared to conventional DJ stent post-endoscopic surgeries in urology, in terms of urinary and pain index, as well as the work performance domain of USSQ. Limitations include the small number of studies, heterogeneity in study design, and differences in PSS type used.</p>","PeriodicalId":8113,"journal":{"name":"Arab Journal of Urology","volume":"24 2","pages":"99-107"},"PeriodicalIF":1.2,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13045176/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147621530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Point-of-care ultrasonography for suprapubic bladder aspiration in pediatric patients: A systematic review and meta-analysis.","authors":"Mohammed F Abosamak, Eman E Shaban, Ali Elkandow, Mohamed Gafar Abdelrahim, Amira Shaban, Ahmed Shaban, Ahmed Hussien Mahmoud, Hany A Zaki","doi":"10.1080/20905998.2025.2557135","DOIUrl":"https://doi.org/10.1080/20905998.2025.2557135","url":null,"abstract":"<p><strong>Background: </strong>Suprapubic aspiration (SPA) is a reliable method for obtaining urine samples in infants to diagnose urinary tract infections (UTIs). However, when performed blindly, the procedure often has low success rates. The increasing use of point-of-care ultrasound (POCUS) across clinical settings offers the opportunity to guide SPA in real time, potentially improving outcomes. This systematic review and meta-analysis examined whether POCUS guidance increases the success of SPA in infants and neonates compared to blind techniques.</p><p><strong>Methods: </strong>A comprehensive search of PubMed, MEDLINE, Web of Science, Cochrane Library, and Google Scholar identified eligible studies that enrolled infants or neonates and compared ultrasound-guided versus blind SPA performed by clinicians (excluding procedures done in radiology departments). Data extraction was conducted independently by two reviewers, and risk of bias was assessed using the Cochrane ROB-2 tool. Statistical analyses were performed in Review Manager, with results presented in forest and funnel plots.</p><p><strong>Results: </strong>Five studies involving 351 infants and neonates met inclusion criteria. Two were conducted in neonatal intensive care units and three in emergency departments. Pooled analyses showed that POCUS guidance significantly improved first-attempt success rates (OR 19.16, 95% CI: 6.17-59.52, <i>p</i> < 0.00001) and overall success rates (OR 6.50, 95% CI: 2.87-14.73, <i>p</i> < 0.00001) compared with blind SPA. Heterogeneity was low (I² = 18%). Procedure times did not differ significantly between groups (MD 6.59 minutes, 95% CI: 1.10-14.27, <i>p</i> = 0.09). Importantly, no evidence of publication bias was detected.</p><p><strong>Conclusion: </strong>This meta-analysis demonstrates that POCUS guidance substantially enhances both first-attempt and overall success of SPA in infants, making it a highly effective technique for diagnosing UTIs in emergency and critical care contexts. Nevertheless, blind SPA remains a viable option in resource-limited settings, provided that infants are adequately prehydrated.</p>","PeriodicalId":8113,"journal":{"name":"Arab Journal of Urology","volume":"24 2","pages":"138-148"},"PeriodicalIF":1.2,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13045168/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147621504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Arabic version of the original (long-form) neurogenic bladder symptoms score validity and reliability in patients with lower urinary tract disorders: A multi-center evaluation.","authors":"Diaa-Eldin Taha, Ali Ibrahim, Abdelwahab Hashim, Salem Bahdilh, Ibrahim Alowidah, Mohamed Ehab, Ali Abdel Raheem","doi":"10.1080/20905998.2025.2555083","DOIUrl":"https://doi.org/10.1080/20905998.2025.2555083","url":null,"abstract":"<p><strong>Background: </strong>The long (original) form of neurogenic bladder symptoms score (NBSS) entails full assessment of the neurogenic status of the patient that is not included in the short form. The aim of this study was to examine the psychometric qualities of the Arabic NBSS among those suffering from neurogenic lower urinary tract dysfunction (NLUTS).</p><p><strong>Methods: </strong>The Arabic-language study included patients with NLUTS. Among the psychometric attributes that were looked at were construct validity, content validity, internal consistency, and test-retest dependability. Cronbach's alpha and the Intraclass Correlation Coefficient (ICC) were used, respectively, to assess internal consistency and test-retest reliability. In order to evaluate construct validity, the Qualiveen questionnaire was compared to the NBSS.</p><p><strong>Results: </strong>The study included 255 NLUTS patients. The internal consistency of the NBSS overall score was found to be variable, with Cronbach's α of 0.82 for both the overall score and each of its subdomains (urinary incontinence: 0.94, storage/voiding: 0.86, consequences: 0.88). Thirty days (±3.6 days) after the baseline version, 233/247 (84%) patients completed and returned their questionnaires for test-retest reliability. The overall score had an ICC of 0.92, while the subdomains of storage/voiding, urine incontinence, and repercussions had ICCs of 0.92, 0.83, and 0.80, respectively. The correlation study demonstrated the strong construct validity of the Arabic NBSS-SF version.</p><p><strong>Conclusion: </strong>Relevant psychometric characteristics, including content, construct test-retest reliability, internal consistency, and validity, can be found in the Arabic version of the NBSS. The NBSS in Arabic is appropriate for usage in study and clinical contexts.</p><p><strong>Clinical trial registration no: </strong>H1R1-27-Dec22-01-MKSU 51-1-16.</p>","PeriodicalId":8113,"journal":{"name":"Arab Journal of Urology","volume":"24 2","pages":"155-160"},"PeriodicalIF":1.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13045189/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147621600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of varicocelectomy prior ICSI on clinical and neonatal outcomes: A multilevel analysis.","authors":"Salah Elbashir, Ayman Rashed, Ahmed M Fathy, Hosam Abu El-Nasr, Tamer Diab","doi":"10.1080/20905998.2025.2550137","DOIUrl":"https://doi.org/10.1080/20905998.2025.2550137","url":null,"abstract":"<p><strong>Purpose: </strong>Little is known about the effectiveness and safety of varicocele repair in patients with male factor infertility undergoing ICSI treatment. Data concerning neonatal outcomes is lacking. We aimed to investigate the effect of varicocele repair prior ICSI.</p><p><strong>Methods: </strong>We analyzed retrospective data from June 2016 to January 2024 using propensity score regression analyses. We compared embryological, clinical and neonatal outcomes. We also evaluated the effect of cofounders on the rate of live birth using multivariate analysis.</p><p><strong>Results: </strong>Data from 582 ICSI cycles showed no association between livebirth and varicocele repair for male-factor patients undergoing ICSI (aOR 0.81[95% CI0.52, 1.25]; <i>p</i> = 0.3) in the adjusted multilevel logistic analysis. Four hundred and four ICSI cycles were included in the propensity score regression analysis, which confirmed the same non-significant increase of livebirth and other embryological and clinical outcomes. Data about neonatal outcomes were similar between the two groups, except for the rate of very preterm birth were higher in the varicocelectomy group compared to the untreated varicocele group.</p><p><strong>Conclusion: </strong>In male-factor infertility associated with varicocele and undergoing ICSI treatment, varicocelectomy does not significantly increase the odds of live birth compared with untreated varicocele. The increased number of very preterm birth in the varicocelectomy group may be related to the high number of multiple gestations exists in the varicocelectomy group and may not correlate to the procedures itself. Further well-powered prospective trails remain warranted.</p>","PeriodicalId":8113,"journal":{"name":"Arab Journal of Urology","volume":"24 2","pages":"114-120"},"PeriodicalIF":1.2,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13045194/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147621547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The outcome of transurethral seminal vesiculoscopy regulated by Endoscopic Seminal Vesicle Milking Test in treating ejaculatory duct obstruction: A prospective cohort.","authors":"Mohamed Omar, Tarek Amin, Atef Badawy, Mohamed Selim","doi":"10.1080/20905998.2025.2546256","DOIUrl":"https://doi.org/10.1080/20905998.2025.2546256","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to evaluate the effectiveness of Endoscopic Seminal Vesicle Milking Test combined with seminal vesiculoscopy with a 4.5 Fr ureteroscope as a minimally invasive approach for diagnosing and treating ejaculatory duct obstruction while preserving ejaculatory function.</p><p><strong>Materials and methods: </strong>A prospective cohort study was conducted, involving 19 male patients with suspected ejaculatory duct obstruction. Endoscopic Seminal Vesicle Milking Test was used for initial diagnosis & confirming obstruction, followed by seminal vesiculoscopy using a 4.5 Fr ureteroscope. Pre- and post-operative seminal parameters, complications, and conception rates were analyzed over one year.</p><p><strong>Results: </strong>Among 19 patients, Endoscopic Seminal Vesicle Milking Test excluded 3 cases of functional obstruction, while 2 cases excluded due to lost follow-up. Among the 14 completing the protocol, 9 had successful sperm retrieval, with significant improvements in seminal parameters (volume: 1.96 ± 0.98 mL, concentration: 16.9 ± 18.4 million/mL, motility: 19.1 ± 11.7%). While in the other five patients, seminal vesiculoscopy failed to retrieve sperms. Hence, Vasography was performed and revealed obstructed vas deferens. Four patients achieved conception within a year. Minor complications included transient hematuria and hematospermia, with one case of recurrent epididymitis managed conservatively.</p><p><strong>Conclusion: </strong>The combination of Endoscopic Seminal Vesicle Milking Test and seminal vesiculoscopy offers a promising, minimally invasive solution for ejaculatory duct obstruction, demonstrating favorable outcomes in sperm retrieval and conception rates with minimal complications. Further multicenter trials are recommended to validate these findings.</p>","PeriodicalId":8113,"journal":{"name":"Arab Journal of Urology","volume":"24 2","pages":"121-126"},"PeriodicalIF":1.2,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13045197/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147621652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interventions to decrease pain and anxiety in patients undergoing urodynamic study: Is there any clear evidence? A systematic review and meta-analysis.","authors":"Albert Ciam, Zola Wijayanti, M Garidya Bestari","doi":"10.1080/20905998.2025.2526979","DOIUrl":"10.1080/20905998.2025.2526979","url":null,"abstract":"<p><p>Urodynamic study (UDS) is a valuable diagnostic procedure for assessing lower urinary tract symptoms but often induces pain and anxiety due to its invasive nature. This systematic review and meta-analysis aimed to evaluate the effectiveness of various interventions to reduce pain and anxiety in patients undergoing UDS. A comprehensive search was conducted in PubMed, ScienceDirect, EMBASE, and EBSCO up to October 2024. Twenty-two studies, including randomized controlled trials and observational studies, were included. Risk of bias was assessed using RoB 2, ROBINS-I, and the Newcastle-Ottawa Scale. Meta-analysis using Review Manager 5.3 showed that providing detailed information to patients significantly reduced pain (SMD: 0.84; 95% CI: 0.20-1.48; <i>p</i> = 0.01), while music therapy and anesthetic agents did not yield significant effects. The overall pooled effect on pain was not statistically significant. For anxiety, the pooled analysis indicated a modest but significant reduction (SMD: 0.57; 95% CI: 0.11-1.02; <i>p</i> = 0.04), despite high heterogeneity. Interventions such as mindfulness, aromatherapy, and heating pads showed potential in individual studies but were not included in meta-analysis due to limited data. The findings highlight that while certain interventions may alleviate discomfort during UDS, evidence remains inconsistent. Well-designed, large-scale trials are needed to establish standardized approaches for enhancing patient comfort during UDS.</p>","PeriodicalId":8113,"journal":{"name":"Arab Journal of Urology","volume":"24 1","pages":"90-98"},"PeriodicalIF":1.2,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12777781/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145931953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An in vitro study evaluating the internal pressure during RIRS of suction ureteral access sheath versus traditional sheath.","authors":"Shusheng Liu, Guanghan Zhang, Chuann Chai, Yuqun Li, Pasin Limudomporn, Weijie Liu, Jian Zhong, Xuliang Pang, Guoyao Ai, Zhicong Huang, Guohua Zeng, Wei Zhu","doi":"10.1080/20905998.2025.2520126","DOIUrl":"10.1080/20905998.2025.2520126","url":null,"abstract":"<p><strong>Introduction: </strong>Flexible ureteroscopy (fURS) remains the gold standard for managing ureteral and renal calculi. The integration of vacuum suction ureteral access sheaths has demonstrated improved stone clearance rates. Through an in vitro fURS model, this study systematically validates the sheath's efficacy in regulating intraluminal pressure across diverse operational parameters, providing mechanical insights for clinical optimization.</p><p><strong>Methods: </strong>An 8.6Fr disposable flexible ureteroscope was utilized to measure intraluminal pressure within a silicone urinary tract model fabricated using 3D printing technology. The experiment was conducted under three configurations of ureteral access sheaths (UAS): (1) conventional UAS, (2) negative pressure suction sheath with an open vent, and (3) negative pressure suction sheath with a fully closed vent. Intraluminal pressure and irrigation flow rate were recorded for various UAS sizes under irrigation pressures ranging from 10 to 240 mmHg.</p><p><strong>Results: </strong>Under varying infusion pressure conditions, the negative pressure sheath with an open vent exhibited slightly lower intraluminal ureteral pressure compared to the traditional sheath; however, this difference was not statistically significant (<i>p</i> = 0.56). In contrast, when using the closed vent method, the negative pressure aspiration sheath demonstrated a significantly distinct change in intraluminal pressure compared to both the traditional sheath and its open vent mode (<i>p</i> < 0.01). Additionally, the choice of ureteral sheath size had a profound impact on intraluminal pressure, with larger sheath sizes associated with lower pressure levels under the same infusion pressure (<i>p</i> < 0.01).</p><p><strong>Conclusions: </strong>During ureteroscopy procedures, intraluminal pressure within the ureter increases proportionally with irrigation pressure. However, the application of negative pressure using a closed vent can effectively mitigate this rise in intraluminal pressure.</p>","PeriodicalId":8113,"journal":{"name":"Arab Journal of Urology","volume":"24 1","pages":"28-32"},"PeriodicalIF":1.2,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12777839/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145931686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}