Arab Journal of Urology最新文献

{"title":"Long-term consequences of sexually transmitted infections on men's sexual function: A systematic review.","authors":"Ralf Henkel","doi":"10.1080/2090598X.2021.1942414","DOIUrl":"https://doi.org/10.1080/2090598X.2021.1942414","url":null,"abstract":"<p><p><b>Objective</b>: To systematically review the available literature on the long-term effects of sexually transmitted diseases (STIs) on male reproductive functions. <b>Methods:</b> A PubMed search was conducted on 3 January 2021, and as a result, 952 articles were retrieved. Exclusion of irrelevant articles resulted in 36 articles, dating from 1998 to 2020, which were analysed. <b>Results:</b> Only 52.8% of these articles described original research, while the rest were reviews. The majority (26) of the articles dealt with bacterial infections, of which 20 described <i>Chlamydia trachomatis</i>. There were 11 articles that described research on viruses, with five on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The analysis of the articles showed further that not much new knowledge on the long-term effects on male reproductive functions has been added. The existing knowledge that ascending infections can cause epididymo-orchitis, prostatitis or urethritis was confirmed. Due to epithelial inflammatory responses these infections can result in scarring with resulting infertility due to obstruction. These effects were described for <i>Chlamydia trachomatis, Neisseria gonorrhoeae, Mycoplasma genitalium</i> or <i>Treponema pallidum</i>, as well as for the Zika and SARS-CoV-2 viruses. Even trichomoniasis can lead to long-term compromised male fertility if not treated. <b>Conclusion:</b> In conclusion, problem awareness needs to be raised and more research on this important topic needs to be conducted.</p>","PeriodicalId":8113,"journal":{"name":"Arab Journal of Urology","volume":"19 3","pages":"411-418"},"PeriodicalIF":1.5,"publicationDate":"2021-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/2090598X.2021.1942414","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39441350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fresh vs frozen testicular sperm for assisted reproductive technology in patients with non-obstructive azoospermia: A systematic review.","authors":"Medhat Amer,&nbsp;Emad Fakhry","doi":"10.1080/2090598X.2021.1932303","DOIUrl":"https://doi.org/10.1080/2090598X.2021.1932303","url":null,"abstract":"<p><strong>Objective: </strong>: To review the debate about the routine use of cryopreserved testicular sperm for intracytoplasmic sperm injection (ICSI) from patients with non-obstructive azoospermia (NOA), as some authors suggest repeating sperm retrieval in such cases due to poorer ICSI results when frozen-thawed testicular sperm is used compared with fresh sperm.</p><p><strong>Methods: </strong>: A systematic literature review was performed in August 2020 using the Medical Literature Analysis and Retrieval System Online (MEDLINE), Web of Science databases and the Excerpta Medica dataBASE (EMBASE), and we included 26 studies that were considered eligible for this systematic review.</p><p><strong>Results: </strong>: In all, 1189 publications were screened and 26 articles were included in the systematic review. Three meta-analysis reviews were included and they all concluded that the use of fresh and frozen sperms for ICSI from patients with NOA showed comparable fertilisation and pregnancy rates.</p><p><strong>Conclusion: </strong>: The use of frozen testicular sperm from men with NOA results in fertilisation and clinical pregnancy rates similar to those of fresh sperm. This may encourage fertility centres to use frozen testicular sperm samples, as this policy has certain advantages that would help with organising their workflow.<b>Abbreviations</b>: CPR: clinical pregnancy rate; 2PN%: two pronuclei % fertilisation rate; ICSI: intracytoplasmic sperm injection; NOA: non-obstructive azoospermia; OA, obstructive azoospermia; SCO: Sertoli cell-only syndrome; (micro-)TESE: (microsurgical) testicular sperm extraction.</p>","PeriodicalId":8113,"journal":{"name":"Arab Journal of Urology","volume":"19 3","pages":"247-254"},"PeriodicalIF":1.5,"publicationDate":"2021-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/2090598X.2021.1932303","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39440450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Low-intensity extracorporeal shockwave therapy for erectile dysfunction.","authors":"Onder Canguven, Kareim Khalafalla, Abdulla Al Ansari","doi":"10.1080/2090598X.2021.1948158","DOIUrl":"10.1080/2090598X.2021.1948158","url":null,"abstract":"<p><p><b>Objectives</b>: To review the current evidence of clinical effectiveness of low-intensity extracorporeal shockwave therapy (LI-ESWT) treatment for erectile dysfunction (ED).</p><p><strong>Methods: </strong>A selective database search using Medical Subject Headings (MeSH) terms 'low intensity extracorporeal shock wave therapy' and 'erectile dysfunction' was conducted in accordance with the Preferred Reporting Items for Systemic Reviews and Meta Analyses (PRISMA) guidelines to review the effectiveness of LI-ESWT for ED. We performed a systematic search of publications using the PubMed and Web of Science databases (January 2010-December 2020) for prospective randomised clinical trials (RCTs). The success rate of LI-ESWT associated with ED were recorded and analysed.</p><p><strong>Results: </strong>A total of 106 articles were reviewed after searching for the keywords. Overall, 11 RCTs were included in this systematic review. A total of 920 male patients were treated in 11 RCTs. The patients' ages ranged from 18 to 80 years and they had ≥3 months of ED symptoms. Vasculogenic and neurogenic causes were addressed in 81% and 19% of patients, respectively. Of the 920 patients, 348 patients had a statistically significant improvement in their erectile function after LI-ESWT; however, 572 did not have a statistically significant improvement.</p><p><strong>Conclusions: </strong>The present review found that LI-ESWT has a role in ED treatment in laboratory studies, but its role in human clinical trials is still controversial. Further good quality studies need to be conducted to properly assess its true potential in ED treatment.</p>","PeriodicalId":8113,"journal":{"name":"Arab Journal of Urology","volume":"19 3","pages":"340-345"},"PeriodicalIF":1.5,"publicationDate":"2021-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451630/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39462408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tips and tricks in the management of inflatable penile prosthesis infection: A review.","authors":"Scott C Brimley,&nbsp;Ayad Yousif,&nbsp;Joseph Kim,&nbsp;Wayne J G Hellstrom","doi":"10.1080/2090598X.2021.1946335","DOIUrl":"https://doi.org/10.1080/2090598X.2021.1946335","url":null,"abstract":"<p><strong>Objective: </strong>To review the management of inflatable penile prosthesis (IPP) infection.<b>Methods</b>: The 'gold-standard' treatment for medication-refractory erectile dysfunction is the IPP, wherein the most dreaded complication is infection. To prevent and manage an infected IPP requires a strict protocol during the pre-, intra-, and postoperative course. A variety of techniques and antibiotics are used in conjunction with IPP implantation to prevent contamination. This modified Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) review of the literature examines the current practices by leading urologists in the management of IPP infection, as well as provides insights for improved patient outcomes.</p><p><strong>Results: </strong>: Patient selection is important to reduce IPP infections, and those with risk factors need to be optimised prior to surgery. Proper antibiotic prophylaxis includes pre-, intra-, and postoperative administration. As most infections derive from normal skin flora, every measure must be taken to sterilise the skin and avoid direct device skin contact. Up to 3% of virgin IPPs develop infections and this number increases to 18% in revision cases. Antibiotic coverage depends on the presenting microbe, which can vary significantly between patients.</p><p><strong>Conclusions: </strong>: A greater success in IPP implantation can be attributed to appropriate prophylaxis, field sterilisation, and surgical technique. For those implants that do become infected, often erectile function can be preserved by immediate antibiotic coverage combined with salvage procedures.</p>","PeriodicalId":8113,"journal":{"name":"Arab Journal of Urology","volume":"19 3","pages":"346-352"},"PeriodicalIF":1.5,"publicationDate":"2021-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/2090598X.2021.1946335","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39441342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alternative medicine and herbal remedies in the treatment of erectile dysfunction: A systematic review.","authors":"Kristian Leisegang,&nbsp;Renata Finelli","doi":"10.1080/2090598X.2021.1926753","DOIUrl":"10.1080/2090598X.2021.1926753","url":null,"abstract":"<p><p><b>Objectives</b>: To systematically review and discuss the current evidence from placebo-controlled clinical trials that investigated the use of alternative medicines and herbal remedies in the management of erectile dysfunction (ED). <b>Methods</b>: A Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA)-based systematic review using specific keyword combinations was conducted on the PubMed and Scopus databases. Randomised controlled trials investigating herbal medicine in at least one group and using the International Index of Erectile Function (IIEF) as an outcome in patients primarily diagnosed with ED were included for review. <b>Results</b>: Following the literature search, screening and eligibility analysis, a total of 42 articles were included. The 42 articles were categorised as single herb extractions (<i>n</i> = 14), combination herbal formula (<i>n</i> = 5), combination of herbal formula and non-herbal nutraceuticals (<i>n</i> = 7), non-herbal nutraceuticals (<i>n</i> = 5), acupuncture and moxibustion (<i>n</i> = 2), diet and nutrition (<i>n</i> = 3), exercise (<i>n</i> = 5), and topical treatments (<i>n</i> = 1). Based on the results, Korean ginseng, Pygnogenol and Prelox, <i>Tribulus terrestris, Lepidium meyenii</i>, L-arginine, acupuncture and lifestyle interventions were the more predominantly investigated treatments interventions for ED. <b>Conclusions</b>: <i>Panax ginseng</i>, Pygnogenol, Prelox and <i>Tribulus terrestris</i> have promising evidence as herbal products, alongside L-arginine as a nutritional supplement, for ED based on IIEF outcomes, and warrant further clinical investigation. The mechanisms of action remain unclear, but each of these appears to in part increase nitric oxide synthesis. Importantly, improved diet and exercise should be considered, particularly in patients with obesity or diabetes mellitus.</p>","PeriodicalId":8113,"journal":{"name":"Arab Journal of Urology","volume":"19 3","pages":"323-339"},"PeriodicalIF":1.5,"publicationDate":"2021-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/2090598X.2021.1926753","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39462409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can high-dose tranexamic acid have a role during transurethral resection of the prostate in large prostates? A randomised controlled trial.","authors":"Mohamed Samir, Ahmed M Saafan, Rania M Afifi, Ahmed Tawfick","doi":"10.1080/2090598X.2021.1932125","DOIUrl":"10.1080/2090598X.2021.1932125","url":null,"abstract":"<p><strong>Objectives: </strong>To assess the efficacy and safety of high-dose tranexamic acid (TXA) during bipolar transurethral resection of the prostate (B-TURP) in patients with large prostates compared to placebo.</p><p><strong>Patients and methods: </strong>From February 2018 to May 2020, 204 patients with enlarged prostates of 80-130 g and in need of surgical intervention were randomised into two groups. Patients in Group A underwent B-TURP and received TXA as an intravenous loading dose of 50 mg/kg over 20 min before induction of anaesthesia followed by a maintenance infusion of 5 mg/kg/h until resection was completed. The patients in Group B (placebo) received a saline infusion of a similar volume.</p><p><strong>Results: </strong>There was highly significant drop in haemoglobin in the placebo group at 4- and 24-h postoperatively compared with the TXA group (<i>P</i> < 0.001). However, there was no significant difference in the blood transfusion rate between the two groups with five patients (5.5%) in the placebo group and four (4.2%) in the TXA group requiring a transfusion (<i>P</i> = 0.74). The procedural time was significantly less in the TXA group vs the control group, at a mean (SD) of 79.93 (22.18) vs 90.91 (21.4) min (<i>P</i> = 0.001). Also, the intraoperative irrigation fluid volume and postoperative irrigation duration were significantly less in the TXA group vs the control group, at a mean (SD) of 19.21 (3.13) vs 23.05 (3.8) L and 14.75 (5.15) vs 18.33 (5.96) h, respectively (<i>P</i> = 0.001). Catheterisation and hospital stay durations were comparable between both groups (<i>P</i> = 0.384 and <i>P</i> = 0.388, respectively). No complications were recorded with use of high-dose TXA.</p><p><strong>Conclusion: </strong>High-dose TXA was effective in controlling blood loss during B-TURP in patients with large prostates, with no adverse drug reactions.</p>","PeriodicalId":8113,"journal":{"name":"Arab Journal of Urology","volume":"20 1","pages":"24-29"},"PeriodicalIF":1.3,"publicationDate":"2021-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881071/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47169896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vitamins as primary or adjunctive treatment in infertile men with varicocele: A systematic review.","authors":"Georgios Tsampoukas,&nbsp;Kristiana Gkeka,&nbsp;Athanasios Dellis,&nbsp;Dominic Brown,&nbsp;Antigoni Katsouri,&nbsp;Ahmed Alneshawy,&nbsp;Mohamad Moussa,&nbsp;Athanasios Papatsoris,&nbsp;Noor Buchholz","doi":"10.1080/2090598X.2021.1932124","DOIUrl":"10.1080/2090598X.2021.1932124","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the usage and the efficacy of vitamins as primary or adjuvant treatment in infertile men with varicocele.</p><p><strong>Methods: </strong>A systematic search in PubMed, the Medical Literature Analysis and Retrieval System Online (MEDLINE) and Cochrane Library with the terms (varicocele) AND (vitamins) was performed. We searched for studies: a) reporting the administration of vitamins (individually or as part of a complex) in men with varicocele and infertility, b) primarily or adjuvant to invasive treatment, and c) reporting the impact on semen parameters and/or pregnancy rates. Exclusion criteria were animal, adolescent and non-English studies, grey literature and trials reporting abstracts only.</p><p><strong>Results: </strong>Seven studies were identified eligible for qualitative analysis. All studies were randomised except one (case series). Vitamins were administered dominantly as part of antioxidant complex and only two studies used vitamins (C and E, respectively) as sole agent. In two studies, vitamin monotherapy resulted in improvement in semen quality, but the effect on pregnancy rates is unknown. One study reported no efficacy of adjuvant multivitamin treatment after embolisation in terms of both semen quality and pregnancy rates. Finally, four studies reported a positive effect of vitamins on semen parameters after varicocelectomy, but the effect on pregnancy rates is conflicting; one study reported improved pregnancy rates with adjuvant treatment, two studies did not evaluate the pregnancy rates, and in one study the outcome was unclear due to missing data.</p><p><strong>Conclusions: </strong>Vitamins have been used mostly as part of an antioxidant panel for the management of infertile men with varicocele. Most studies have found a positive impact on semen parameters in selected men with varicocele and infertility, as primary or adjuvant treatment. However, the clinical benefit of vitamins administration on pregnancy rate is under-evaluated and should be the target of future research.</p>","PeriodicalId":8113,"journal":{"name":"Arab Journal of Urology","volume":"19 3","pages":"264-273"},"PeriodicalIF":1.5,"publicationDate":"2021-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/2090598X.2021.1932124","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39462403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effectiveness of psychological interventions alone, or in combination with phosphodiesterase-5 inhibitors, for the treatment of erectile dysfunction:A systematic review.","authors":"Sandrine Atallah, Asad Haydar, Teddy Jabbour, Peter Kfoury, Georgio Sader","doi":"10.1080/2090598X.2021.1926763","DOIUrl":"10.1080/2090598X.2021.1926763","url":null,"abstract":"<p><p><b>Objectives</b>: To highlight the efficacy of various psychological interventions (PI) when used in combination with, or in place of, phosphodiesterase-5 inhibitors (PDE-5i), as compared to the traditional treatment of men with erectile dysfunction (ED) with PDE-5i alone. <b>Methods</b>: A comprehensive literature review for the years 2005-2020 via MEDLINE and PubMed. We included randomised controlled trials that compared the use of either PDE-5i alone, PI alone or a combination of PDE-5i and PI in the treatment of psychogenic ED. All studies included were performed in adults aged 19-55 years and were written in English. <b>Results</b>: A total of 13 articles, with an overall sample of 597 men, were included in this systematic review. The results show that the combination of PI and PDE-5i was more effective than either PI or PDE-5i alone, on erectile function and long-term sexual satisfaction in men with psychogenic ED. Combined interventions were found to be significantly superior to medical treatment in seven studies and to PI alone in one study. In comparing PI to PDE-5i, two studies found PI to be significantly superior to PDE-5i use. In three other studies, PI was found significantly superior to no treatment at all, although some participants in the control group had taken PDE-5i. <b>Conclusions</b>: The combination of PDE-5i with PI shows real promise for the treatment of psychogenic ED. However, no conclusions could be made about what PI is more promising than the other and larger studies are needed to confirm these initial findings. <b>Abbreviations</b>: CBT: cognitive behavioural therapy; CBST: cognitive behavioural sex therapy; COVID-19: coronavirus disease 2019; ED: erectile dysfunction; EDITS: Erectile Dysfunction Inventory of Treatment Satisfaction; GPT, group psychotherapy: IIEF(-EF) (-OS) (-SD): International Index of Erectile Function (erectile functioning) (overall sexual satisfaction) (level of sexual desire); ITP: integrative treatment protocol; MHI: Mental Health Inventory; PDE-5i: phosphodiesterase-5 inhibitors; PI, psychological interventions; QoL: quality of life; RCT: randomised controlled trial; SHIM: Sexual Health Inventory for Men.</p>","PeriodicalId":8113,"journal":{"name":"Arab Journal of Urology","volume":"19 3","pages":"310-322"},"PeriodicalIF":1.3,"publicationDate":"2021-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451609/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39462407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stress urinary incontinence among Jordanian women living in rural areas: Prevalence, associated factors and self-management behaviours.","authors":"Rami AlAzab,&nbsp;Reema Ahmad Alomari,&nbsp;Yousef S Khader,&nbsp;Muntaha Gharaibeh","doi":"10.1080/2090598X.2021.1926751","DOIUrl":"https://doi.org/10.1080/2090598X.2021.1926751","url":null,"abstract":"<p><p><b>Objectives</b>: To assess the prevalence of stress urinary incontinence (SUI) among Jordanian women aged 35-65 years living in in rural areas and its associated risk factors. <b>Patients and methods</b>: A cross-sectional study utilising a convenience sample of 1000 non-pregnant women who were recruited from healthcare centres and community settings. Participants completed a structured questionnaire that included demographic and gynaecological data, and questions about SUI. Descriptive analysis and logistic regression were used to analyse the data. <b>Results</b>: Overall, 551 women (55.1%) reported having SUI with a duration of 37.9-47.6 months. The mean age of the women was 45.38 years and 29.6% were post-menopausal. Moreover, 40.6% were overweight, 38.9% obese, and 16.9% were smokers. Married women comprised 81.8%; with 37.1% having four to six children and 92.8% had a normal delivery, whereas 28% had a history of caesarean section. Coughing was the major precipitating factor for SUI (87.7%). In addition, 64.8% of women with SUI did not avoid activities that precipitated SUI such as housekeeping and lifting, and 78.6% did not seek any medical care. The major significant correlates for SUI were: high body mass index (odds ratio [OR] 2.506, 95% confidence interval [CI] 1.744-3.600, <i>P</i> < 0.001), being aged >50 years (OR 1.716, 95% CI 1.183-2.489, <i>P</i> = 0.004), a history of gynaecological/pelvic surgery (OR 1.631, 95% CI 1.206-2.205, <i>P</i> = 0.001), and vaginal delivery (OR 1.052, 95% CI 1.004-1.101, <i>P</i> = 0.033). <b>Conclusion</b>: SUI prevalence among Jordanian women is high with symptoms reported in more than a half of study participants. Older age, obesity, a history of gynaecological surgery, and history of vaginal delivery were the major correlates of SUI. Public awareness is needed to identify the condition for early diagnosis and treatment of SUI. <b>Abbreviations:</b> BMI: high body mass index; OR: odds ratio; (M)(S)(U)UI: (mixed) (stress) (urge) urinary incontinence.</p>","PeriodicalId":8113,"journal":{"name":"Arab Journal of Urology","volume":"19 4","pages":"469-472"},"PeriodicalIF":1.5,"publicationDate":"2021-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/2090598X.2021.1926751","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39704781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novel methods to enhance surgical sperm retrieval: a systematic review.","authors":"Eliyahu Kresch,&nbsp;Iakov Efimenko,&nbsp;Daniel Gonzalez,&nbsp;Paul J Rizk,&nbsp;Ranjith Ramasamy","doi":"10.1080/2090598X.2021.1926752","DOIUrl":"10.1080/2090598X.2021.1926752","url":null,"abstract":"<p><p><b>Objectives</b>: To explore the use of novel technologies in sperm retrieval in men with azoospermia due to a production defect. <b>Methods</b>: We performed a Preferred Reporting Items for Systemic Reviews and Meta-Analysis (PRISMA)-compliant systemic literature review for manuscripts focussed on novel sperm-retrieval methods. We identified 30 studies suitable for qualitative analysis. <b>Results and Conclusions</b>: We identified multiple new promising technologies, each with its own distinct set of benefits and limitations, to enhance chances of sperm retrieval; these include the use of multiphoton microscopy, Raman spectroscopy, and full-field optical coherence tomography during a microdissection-testicular sperm extraction procedure. ORBEYE and ultrasonography technologies can also serve to better visualise areas of sperm production. Finally, artificial intelligence technology can play a role in the identification of sperm and, perhaps, better-quality sperm for use with assisted reproduction. <b>Abbreviations:</b> AI: artificial intelligence; ANN: artificial neural network; ART: assisted reproductive technology; 3D: three-dimensional; DNN: deep neural networks; FFOCT: full-field optical coherence tomography; H&E: haematoxylin and eosin; ICSI: intracytoplasmic sperm injection; IVF: <i>in vitro</i> fertilisation; MESA: micro-epididymal sperm aspiration; MeSH: Medical Subject Heading; MPM: multiphoton microscopy; (N)OA: (non-)obstructive azoospermia; SCO: Sertoli cell-only syndrome; SRR: sperm retrieval rates; TESA: testicular sperm aspiration; (micro-)TESE: (microdissection-) testicular sperm extraction; (CE)US: (contrast-enhanced) ultrasonography.</p>","PeriodicalId":8113,"journal":{"name":"Arab Journal of Urology","volume":"19 3","pages":"227-237"},"PeriodicalIF":1.5,"publicationDate":"2021-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/2090598X.2021.1926752","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39440448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}