{"title":"Mental health after orchiectomy: Systematic review and strategic management.","authors":"G Shokaier, M Gross, M Cohen, A Hussein","doi":"10.1080/20905998.2025.2478771","DOIUrl":null,"url":null,"abstract":"<p><p>Orchiectomy, the surgical removal of one or both testicles, is often a life-changing procedure. While it is a critical treatment step for conditions such as testicular cancer, advanced prostate cancer, severe unresolving infection, trauma and gender dysphoria, the associated psychological challenges remain underexplored. Depression, anxiety, body image concerns, and diminished quality of life are prevalent but insufficiently addressed. This review synthesizes available literature to quantify these psychological impacts, explore cultural and demographic influences, and present evidence-based management strategies. The review highlights the importance of pre-operative counselling, testosterone replacement therapy (TRT), cognitive behavioural therapy (CBT), and social support networks. Future research should focus on longitudinal assessments to better understand long-term mental health outcomes post-orchiectomy.</p>","PeriodicalId":8113,"journal":{"name":"Arab Journal of Urology","volume":"23 4","pages":"245-252"},"PeriodicalIF":1.2000,"publicationDate":"2025-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12493607/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Arab Journal of Urology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/20905998.2025.2478771","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"UROLOGY & NEPHROLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Orchiectomy, the surgical removal of one or both testicles, is often a life-changing procedure. While it is a critical treatment step for conditions such as testicular cancer, advanced prostate cancer, severe unresolving infection, trauma and gender dysphoria, the associated psychological challenges remain underexplored. Depression, anxiety, body image concerns, and diminished quality of life are prevalent but insufficiently addressed. This review synthesizes available literature to quantify these psychological impacts, explore cultural and demographic influences, and present evidence-based management strategies. The review highlights the importance of pre-operative counselling, testosterone replacement therapy (TRT), cognitive behavioural therapy (CBT), and social support networks. Future research should focus on longitudinal assessments to better understand long-term mental health outcomes post-orchiectomy.
期刊介绍：
The Arab Journal of Urology is a peer-reviewed journal that strives to provide a high standard of research and clinical material to the widest possible urological community worldwide. The journal encompasses all aspects of urology including: urological oncology, urological reconstructive surgery, urodynamics, female urology, pediatric urology, endourology, transplantation, erectile dysfunction, and urinary infections and inflammations. The journal provides reviews, original articles, editorials, surgical techniques, cases reports and correspondence. Urologists, oncologists, pathologists, radiologists and scientists are invited to submit their contributions to make the Arab Journal of Urology a viable international forum for the practical, timely and state-of-the-art clinical urology and basic urological research.
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