Annals of Medicine and Surgery最新文献

{"title":"Thromboinflammatory pathways in breast cancer: clinical and molecular insights into venous thromboembolism risk - a narrative review.","authors":"Emmanuel Ifeanyi Obeagu","doi":"10.1097/MS9.0000000000003644","DOIUrl":"10.1097/MS9.0000000000003644","url":null,"abstract":"<p><p>Venous thromboembolism (VTE) remains a significant cause of morbidity and mortality in breast cancer patients, particularly in those with advanced disease or undergoing systemic therapies. While breast cancer is not traditionally classified among the most thrombogenic malignancies, accumulating evidence suggests that tumor biology, treatment modalities, and systemic inflammation can collectively heighten thrombotic risk. This has led to a growing interest in the concept of <i>thromboinflammation</i>, wherein the coagulation cascade and inflammatory responses are intricately linked, creating a prothrombotic and tumor-supportive environment. At the molecular level, breast cancer cells and associated stromal elements contribute to a hypercoagulable state through increased expression of tissue factor (TF), release of pro-inflammatory cytokines, and production of TF-bearing extracellular vesicles. Furthermore, components of the innate immune system, particularly neutrophils, promote thrombosis via the formation of neutrophil extracellular traps (NETs). These mechanisms not only facilitate clot formation but also enhance cancer progression, metastasis, and resistance to therapy. Certain aggressive breast cancer subtypes, including triple-negative and HER2-positive tumors, demonstrate heightened thromboinflammatory activity.</p>","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"87 9","pages":"5822-5828"},"PeriodicalIF":1.6,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12401306/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144991355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of isokinetic in the management of patellofemoral pain syndrome: a narrative review.","authors":"Mohammed Noumairi, Maryem Slama, Jihen Bouzaien, Amine Kalai, Younes El Anbari, Ahmed Amine El Oumri","doi":"10.1097/MS9.0000000000003626","DOIUrl":"10.1097/MS9.0000000000003626","url":null,"abstract":"<p><p>Patellofemoral pain syndrome (PFPS) is a common musculoskeletal condition that significantly impacts physical function and quality of life. This review evaluates the role of isokinetic knee strengthening exercises in the management of PFPS, highlighting key findings from recent studies. Isokinetic strengthening, particularly focused on eccentric quadriceps contractions, has shown significant improvements in pain reduction, functional performance, and quadriceps strength. Notably, studies demonstrate enhanced outcomes in PFPS patients with bilateral symptoms, as well as in specific populations such as overweight/obese individuals. Despite these benefits, the evidence suggests that isokinetic exercises alone may not fully maintain functional performance, indicating the need for multimodal rehabilitation strategies like eccentric isometric training that can be combined with closed chain exercises (e.g., squats) to enhance functional transfer. Additionally, isokinetic protocols show promise in addressing impaired proprioception and neuromuscular control, particularly in patients with overexertion-related symptoms. Future research should explore the long-term efficacy, cost-effectiveness, and mechanistic underpinnings of isokinetic training to further refine treatment approaches and enhance clinical outcomes.</p>","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"87 9","pages":"5792-5797"},"PeriodicalIF":1.6,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12401354/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144991102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rare co-occurrence of appendicitis, ovarian dermoid cyst with torsion: a case report.","authors":"Anish Paudyal, Sachin Bhatta, Sphurna Karki, Sanjay Dhungana, Subhash Paudel, Manish Kharel","doi":"10.1097/MS9.0000000000003639","DOIUrl":"10.1097/MS9.0000000000003639","url":null,"abstract":"<p><strong>Introduction: </strong>Simultaneous presentation of acute appendicitis and ovarian torsion is rare and requires urgent surgical intervention due to the high risk of complications, including sepsis and mortality. While adnexal torsion is a known cause of acute abdomen in reproductive-age women, co-presentation with appendicitis is exceptionally uncommon. This case underlines the importance of considering gynecological differentials in women presenting with acute abdominal pain.</p><p><strong>Case presentation: </strong>A 39-year-old woman presented with right lower abdominal pain, fever, and vomiting. Initially diagnosed with an appendicular lump, she was managed conservatively and discharged after symptomatic improvement. Upon recurrence of symptoms, imaging revealed an ovarian dermoid cyst with torsion. Exploratory laparotomy identified a gangrenous ovary with a twisted cyst and adherent appendix. Histopathology confirmed acute appendicitis and a benign dermoid cyst.</p><p><strong>Discussion: </strong>Adnexal torsion occurs when the ovary and fallopian tube twist around their ligaments, often caused by ovarian cysts like dermoid cysts. These cysts are common in young women and can lead to acute abdominal pain, requiring urgent surgery to prevent ovarian damage. Diagnosis is challenging, as symptoms mimic other conditions like appendicitis. Imaging such as ultrasonography or computed tomography is used, and treatment involves surgical untwisting or removal of affected tissues. Torsion sometimes affects nearby organs, like an appendix.</p><p><strong>Conclusion: </strong>This case highlights the rare occurrence of simultaneous appendicitis and ovarian torsion, emphasizing the importance of early diagnosis and surgical intervention.</p>","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"87 9","pages":"6143-6147"},"PeriodicalIF":1.6,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12401295/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144991393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of platelet-rich albumin and fibrin gel in two-stage lateral sinus lift: a prospective study.","authors":"Moteea Barakat, Ali Khalil, Ziad Albash","doi":"10.1097/MS9.0000000000003589","DOIUrl":"10.1097/MS9.0000000000003589","url":null,"abstract":"<p><strong>Background: </strong>Maxillary sinus lift procedures require biomaterials that combine osteogenic potential with structural stability. This study evaluates Albumin-Platelet-Rich Fibrin (Alb-PRF), a novel autologous material, as a standalone graft alternative in two-stage lateral sinus lifts, addressing limitations of rapid resorption in traditional platelet concentrates.</p><p><strong>Methods: </strong>A prospective study was conducted on nine patients (mean age: 48.5 years) with residual bone height <5 mm. Alb-PRF was prepared by heat-treating platelet-poor plasma to form an albumin gel, combined with PRF. The gel was placed via lateral window technique without supplemental grafts. Cone-beam computed tomography (CBCT) assessed vertical bone gain (VBG) and density at 6 months. Statistical analysis used paired <i>t</i>-tests (SPSS v22, α = 0.05).</p><p><strong>Results: </strong>Mean VBG was 5.07 ± 1.78 mm (range: 2.2-7.9 mm), with significant improvement from baseline (3.58 ± 1.2 mm to 8.65 ± 1.75 mm, *<i>P</i>* < 0.001). Radiographic bone density averaged 322.7 ± 36.4 Hounsfield units, indicating homogeneous osteogenesis. One membrane perforation occurred (11.11%), with no postoperative complications.</p><p><strong>Conclusion: </strong>Alb-PRF achieved clinically significant bone gain without traditional grafts, leveraging prolonged scaffold stability (4-6 months) and growth factor release. Its autologous nature and low complication profile make it a promising alternative, though larger studies are needed to validate long-term implant outcomes.</p>","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"87 9","pages":"5409-5416"},"PeriodicalIF":1.6,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12401425/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144991167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative efficacy of sodium-glucose transporter 2 inhibitors on lipid profiles in nonalcoholic fatty liver disease (NAFLD): a comprehensive Bayesian network meta-analysis.","authors":"Ibrahim Khalil, Md Imran Hossain, Mahmuda Akter, Sajjad Ghanim Al-Badri","doi":"10.1097/MS9.0000000000003658","DOIUrl":"10.1097/MS9.0000000000003658","url":null,"abstract":"<p><strong>Background: </strong>Nonalcoholic fatty liver disease (NAFLD) is a global health concern associated with dyslipidemia, obesity, and type 2 diabetes mellitus (T2DM), necessitating effective therapeutic strategies. Sodium-glucose transporter 2 (SGLT-2) inhibitors have shown promise in improving metabolic parameters, but their comparative efficacy in NAFLD remains unclear.</p><p><strong>Methods: </strong>We systematically searched PubMed, Cochrane Library, Scopus, and Embase for randomized controlled trials (RCTs) up to 31 December 2024, involving NAFLD patients treated with SGLT-2 inhibitors versus placebo or standard treatments. Outcomes included changes in low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), total cholesterol, triglycerides, BMI, and HbA1c. A Bayesian NMA was performed using a random-effects model, with mean differences (MD) and 95% credible intervals (CrI) reported. Treatments were ranked using Surface Under the Cumulative Ranking Curve (SUCRA) scores.</p><p><strong>Results: </strong>We evaluated and compared the efficacy of SGLT-2 inhibitors in improving lipid profiles (LDL-C, HDL-C, total cholesterol, and triglycerides), BMI, and HbA1c in patients with NAFLD. Eleven RCTs involving 805 patients were included. Empagliflozin achieved the greatest LDL-C reduction (MD: -8.07 mg/dL, 95% CrI: -25.92 to 1.41; SUCRA: 95.38%), total cholesterol reduction (MD: -15.08 mg/dL, 95% CrI: -58.87 to 5.38; SUCRA: 94.32%), and HbA1c reduction (MD: -0.69%, 95% CrI: -1.52 to -0.06; SUCRA: 81.84%). Ipragliflozin non-significantly increased HDL-C (MD: 2.28 mg/dL, 95% CrI: -1.21 to 4.83; SUCRA: 85.11%) and significantly reduced triglyceride (MD: -22.39 mg/dL, 95% CrI: -39.25 to -7.27; SUCRA: 82.26%). Dapagliflozin resulted in significant BMI reduction (MD: -1.23 kg/m², 95% CrI: -2.11 to -0.41; SUCRA: 73.28%).</p><p><strong>Conclusion: </strong>Empagliflozin and ipragliflozin demonstrated superior efficacy in improving lipid profiles, while dapagliflozin was most effective for BMI reduction in NAFLD patients. These findings align with their cardiovascular and metabolic benefits, offering a multifaceted approach to a complex disease. Further research is needed to confirm long-term effects and optimize treatment strategies for diverse NAFLD populations.</p>","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"87 9","pages":"6008-6022"},"PeriodicalIF":1.6,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12401347/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144991277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A rare presentation of subcutaneous granuloma annulare: a case report of bilateral palmar and dorsal hand nodules with successful management.","authors":"Zainab Srouji, Najem Salem, Rama Ghwich, Munir Mounla, Noura Abdul Rahman","doi":"10.1097/MS9.0000000000003642","DOIUrl":"10.1097/MS9.0000000000003642","url":null,"abstract":"<p><strong>Introduction and importance: </strong>Granuloma annulare (GA) is a benign, self-limited, chronic inflammatory dermatosis predominantly affecting children and young adults. Subcutaneous granuloma annulare (SGA) is a rare variant, chiefly observed in children, characterized by firm, asymptomatic nodules typically located on the lower extremities, buttocks, or scalp. Involvement of the palms or soles is exceptionally rare.</p><p><strong>Case presentation: </strong>We report the case of a healthy teenager presenting with bilateral subcutaneous nodules on both the palmar and dorsal surfaces of the hands. Histopathological examination confirmed the diagnosis of SGA. Given the patient's aesthetic concerns, a treatment regimen of intralesional corticosteroid injections was initiated, leading to complete resolution of the lesions without recurrence during follow-up.</p><p><strong>Clinical discussion: </strong>This case represents the first documented instance of SGA involving both palmar and dorsal surfaces of the hands bilaterally in a healthy adolescent. While SGA is usually self-limited, cosmetic concerns or discomfort may necessitate therapeutic intervention. Intralesional corticosteroids have been employed with variable success in such cases.</p><p><strong>Conclusion: </strong>This case underscores the importance of considering SGA in the differential diagnosis of subcutaneous hand nodules in pediatric patients, even in atypical locations such as the palms and dorsal hands. It also highlights the efficacy of intralesional corticosteroid treatment in achieving satisfactory cosmetic outcomes without recurrence.</p>","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"87 9","pages":"6173-6176"},"PeriodicalIF":1.6,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12401324/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144991326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Shadow of complications in neurosurgery.","authors":"Sayedali Ahmadi, Luis A B Borba, Yam Bahadur Roka, Bipin Chaurasia","doi":"10.1097/MS9.0000000000003629","DOIUrl":"10.1097/MS9.0000000000003629","url":null,"abstract":"","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"87 9","pages":"5370-5372"},"PeriodicalIF":1.6,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12401415/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144991420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between body mass index and the risk of bacterial vaginosis: a systematic review and meta-analysis.","authors":"Omar Khalid Samir Abdelkader, Noheir Ashraf Ibrahem Fathy Hassan, Amro Mahmoud Radi, Mennatallah Kamal, Karrar Hazim Abdul-Karim Al-Qizwini, Abdelrahman Ezzat, Helen A O Popoola-Samuel, Karim Aiash, Ayaan Arora, Amir Elissawy, Eman A Toraih, Yusef Hazimeh, Hani Aiash","doi":"10.1097/MS9.0000000000003655","DOIUrl":"10.1097/MS9.0000000000003655","url":null,"abstract":"<p><strong>Introduction: </strong>Bacterial vaginosis, resulting from vaginal microbiota imbalance and lactobacilli depletion, is the leading cause of abnormally appearing discharge in reproductive-aged women. Bacterial vaginosis is also associated with risk for sexually transmitted infections, preterm birth, and pelvic inflammatory disease. This meta-analysis assessed the association between the risk of bacterial vaginosis (BV) and body mass index (BMI).</p><p><strong>Methods: </strong>We systematically searched electronic databases using terms for weight, vaginosis, obesity, and BMI. We also reviewed gray literature, reference lists, and trials registries and sought the advice of experts. We calculated the overall odds ratios (OR) and the 95% confidence intervals (CI) using fixed-effect model for homogenous data and random-effects models for heterogenous data.</p><p><strong>Results: </strong>Eight observational studies (<i>n</i> = 22 190) were included, with quality assessment scores ranging from 7 to 9. Compared with normal-weight women (BMI 18.5-24.9), underweight women (BMI <18.5) had significantly higher prevalence of bacterial vaginosis (OR: 1.23; 95% CI: 1.12-1.36; <i>P</i> < 0.001). No significant associations were found for overweight (OR: 1.19; 95% CI: 0.95-1.48; <i>P</i> = 0.13) or obesity (OR: 1.29; 95% CI: 0.91-1.82; <i>P</i> = 0.15).</p><p><strong>Conclusion: </strong>Our findings suggest a significant association between underweight status and an increased likelihood of being diagnosed with bacterial vaginosis. However, causality cannot be established due to the observational nature of the included studies. Further prospective research is needed to confirm this relationship.</p>","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"87 9","pages":"5999-6007"},"PeriodicalIF":1.6,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12401329/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144991201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"IgG4 unveiled: navigating the interplay with Crohn's disease - from immunology insights to machine learning.","authors":"Anmol Mohan, Urooj Ghaffar, Ahmad Basharat, Gul Nawaz, Raja Ram Khenhrani, Rimsha, Guillermo de Jesus Aguirre Vera, Priyanka Mohan Lal, Dev Tanush, Muhammad Khuzzaim Khan, Nikhil Duseja, Syeda Laiba Sherazi, Vikash, Vikash Kumar, Dhairya Nanavaty","doi":"10.1097/MS9.0000000000003633","DOIUrl":"10.1097/MS9.0000000000003633","url":null,"abstract":"<p><p>Crohn's disease (CD) is a chronic inflammatory bowel disease characterized by relapsing-remitting episodes and a progressive course that often leads to bowel damage and disability. While the etiology of CD is multifactorial, involving genetic, environmental, and immunological factors, recent studies have highlighted the role of food antigens and the gut microbiome in its pathogenesis. This paper explores the immunological underpinnings of CD, with a focus on the elevated levels of serum immunoglobulin G4 (IgG4) and their correlation with disease severity and therapeutic response. We review clinical trials and case studies that demonstrate the potential of IgG4-guided exclusion diets and intravenous immunoglobulin (IVIG) therapy in ameliorating CD symptoms and inflammation. Additionally, we delve into advancements in machine learning (ML) models that utilize fecal microbiome data, offering promising diagnostic tools for distinguishing CD from ulcerative colitis and non-IBD conditions. The integration of ML in endoscopy and predictive models for therapy complications signifies a leap toward precision medicine in IBD management. This paper underscores the necessity for a nuanced understanding of CD's immunological aspects and the innovative application of ML in its diagnosis and treatment, paving the way for personalized therapeutic strategies and improved patient outcomes.</p>","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"87 9","pages":"5798-5806"},"PeriodicalIF":1.6,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12401333/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144990930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcomes of severely impaired renal function patients with and without dialysis following isolated coronary artery surgery - a retrospective cohort study.","authors":"Alena Krauchuk, Tomasz Hrapkowicz, Piotr Suwalski, Bartłomiej Perek, Marek Jasiński, Tomasz Hirnle, Paweł Nadziakiewicz, Piotr Knapik","doi":"10.1097/MS9.0000000000003488","DOIUrl":"10.1097/MS9.0000000000003488","url":null,"abstract":"<p><strong>Objectives: </strong>Patients with advanced-stage chronic renal failure have poor outcomes following cardiac surgery. Our registry study aimed to compare postoperative and follow-up data between patients who underwent isolated coronary artery surgery with preoperative chronic dialysis and patients with preoperative severe renal impairment who did not require chronic dialysis.</p><p><strong>Methods: </strong>We analyzed 157 948 consecutive adult patients in the Polish National Registry of Cardiac Surgical Procedures (KROK Registry) scheduled for isolated coronary artery surgery between January 2010 and December 2023. Overall, in this cohort, 938 patients underwent chronic dialysis (CD group), and 13 253 patients had severe renal impairment but did not undergo CD (serious renal impairment [SRI] group). Patients in these groups constituted 0.6% and 8.4% of the entire population, respectively. Preoperative data, major postoperative complications, hospital mortality, and mid-term all-cause mortality were compared among patients in CD group and SRI group.</p><p><strong>Results: </strong>Mean age of patients CD group and SRI group was 63.3 ± 9.5 vs. 71.9 ± 8.4 years, respectively (<i>P</i> < 0.001), while the mean EuroSCORE II score in these groups was 4.85% ± 7.03% vs. 5.82% ± 7.76%, respectively (<i>P</i> < 0.001). In-hospital mortality among patients in the CD and SRI groups were 10.9% and 6.3%, respectively (<i>P</i> < 0.001). Patients with preoperative CD had more frequent respiratory complications and reoperations for bleeding. The long-term mortality was also significantly higher in CD group (<i>P</i> < 0.001).</p><p><strong>Conclusion: </strong>Patients with CD had higher in-hospital and long-term mortality rates than those with a preoperative SRI. It is possible that the EuroSCORE II underestimates the risk of coronary bypass grafting in a group of patients with chronic dialysis. It is possible that the coagulation disorders may play role in the higher mortality rates in patients undergoing chronic dialysis.</p>","PeriodicalId":8025,"journal":{"name":"Annals of Medicine and Surgery","volume":"87 8","pages":"4728-4734"},"PeriodicalIF":1.6,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12333711/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144815611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}