Kacper Andruszkiewicz, Mikołaj Filipiak, Jan Radomski, Alicja Wysocka, Małgorzata Paul
{"title":"Disseminated cysticercosis in a non-endemic area of Europe: diagnostic challenges and successful management of an unusual parasitic infection.","authors":"Kacper Andruszkiewicz, Mikołaj Filipiak, Jan Radomski, Alicja Wysocka, Małgorzata Paul","doi":"10.17420/ap71.540","DOIUrl":"https://doi.org/10.17420/ap71.540","url":null,"abstract":"<p><p>Cysticercosis caused by the larval forms of Taenia solium is observed sporadically in humans from nonendemic areas and is challenging to diagnose. We report an extraordinary case of 81-year-old woman from a rural region of Poland with worsening neurological symptoms suspected of brain malignancy. Imaging and serological tests confirmed disseminated cysticercosis with multiple space-occupying lesions located in the brain, soft tissues, and liver. Systemic cysticercosis in a white woman without a history of international travel is an exceptional clinical finding. Treatment with albendazole and corticosteroids led to significant reduction of pathological masses and clinical improvement. This case highlights the importance of considering unusual parasitic infections in neurological evaluations, even in non-endemic areas.</p>","PeriodicalId":7987,"journal":{"name":"Annals of parasitology","volume":"71 ","pages":"11-17"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144180677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Biology and genetics of the poultry red mite (Dermanyssus gallinae) - new targets for eradicating and controlling invasion.","authors":"Sylwia Koziatek-Sadłowska","doi":"10.17420/ap71.541","DOIUrl":"https://doi.org/10.17420/ap71.541","url":null,"abstract":"<p><p>Dermanyssus gallinae is considered to be one of the world's most troublesome ectoparasites of laying hens, with the consequences for the hens being reflected in production rates, including reduced egg quantity and quality. Despite intensive efforts to develop research on this mite, it remains challenging to combat. This article reviews current and recent knowledge on the biology and genetics of D. gallinae, and new targets for control are discussed as identified by the authors of recent publications. It is imperative to acknowledge the significance of this knowledge in order to facilitate the identification of genetic markers associated with the emergence of acaricide resistance. This, in turn, will enable the development of alternative strategies and methods to control D. gallinae.</p>","PeriodicalId":7987,"journal":{"name":"Annals of parasitology","volume":"71 ","pages":"19-25"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144257210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hussein Algahtani, Bader Shirah, Omar Algahtani, Ali H Alassiri
{"title":"Unraveling the enigma of spinal cord schistosomosis: clinical spectrum, diagnosis, and therapeutic insights.","authors":"Hussein Algahtani, Bader Shirah, Omar Algahtani, Ali H Alassiri","doi":"10.17420/ap71.539","DOIUrl":"10.17420/ap71.539","url":null,"abstract":"<p><p>Spinal cord schistosomosis is a rare but significant cause of myelopathy, ranging from asymptomatic egg deposits to severe transverse myelitis. Common in endemic regions, S. mansoni myelopathy presents as acute paraplegia or cauda equina syndrome. Diagnosis involves identifying ova in stool, urine, or rectal biopsy, accompanied by peripheral eosinophilia. Treatment includes praziquantel and corticosteroids, with laminectomy reserved for specific cases. Prognosis varies, with around one-third recovering completely, one-third with residual deficits, and one-third remaining unchanged or deteriorating, particularly in necrotic myelitis. Recognition in endemic areas is critical for timely intervention and improved outcomes in this potentially treatable myelopathy.</p>","PeriodicalId":7987,"journal":{"name":"Annals of parasitology","volume":"71 ","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144180391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Determination of the anti-protozoal activity of medicinal agents using the phenomenon of plaque formation by Acanthamoeba spp.","authors":"Volodymyr Shyrobokov, Vadym Poniatovskyi, Valeriia Poniatovska, Anastasiia Romanchyshyna, Rusłan Sałamatin","doi":"10.17420/ap7001.522","DOIUrl":"10.17420/ap7001.522","url":null,"abstract":"<p><p>Representatives of the genus Acanthamoeba are among the most widespread protists in the environment. They have a ubiquitous distribution and can sometimes cause quite serious pathologies in humans. The treatment ofp rotozoal infections caused by free-living amoebae is currently limited and often unsuccessful. In the presented investigation, amebicidal activity was determined against both the trophozoites and cysts of Acanthamoeba spp., which were isolated during the microbiological examination of environmental objects. The inhibitory activity of drugs in vitro was determined using the authors' proposed method, which is based on the plaque formation phenomenon: this is initiated by free-living amoebae when cultured in agar containing the bacteria Cellulosimicrobium sp. strain bent-1. Based on a series of experimental studies, the paper proposes a reliable and inexpensive method for determining the anti-protozoal activity of medicinal agents, which will significantly complement the current screening method system when studying existing drugs, or new drugs during their development stage.</p>","PeriodicalId":7987,"journal":{"name":"Annals of parasitology","volume":"70 1","pages":"15-22"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141465736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jozef Oboňa, Peter Manko, Laura Mlynárová, Alexandru-Mihai Pintilioaie, Laura-Elena Topală, Martin Hromada, Jindřich Roháček
{"title":"Carnus hemapterus (Diptera: Carnidae) - an unusual parasite on European Roller from Romania.","authors":"Jozef Oboňa, Peter Manko, Laura Mlynárová, Alexandru-Mihai Pintilioaie, Laura-Elena Topală, Martin Hromada, Jindřich Roháček","doi":"10.17420/ap7003.533","DOIUrl":"https://doi.org/10.17420/ap7003.533","url":null,"abstract":"<p><p>An uncommon host-parasite relationship is presented: Carnus hemapterus Nitzsch, 1818 (Diptera: Carnidae) parasiting fledgling of Coracias garrulus Linnaeus, 1758. This host association has hitherto not been recorded from the territory of Romania.</p>","PeriodicalId":7987,"journal":{"name":"Annals of parasitology","volume":"70 3","pages":"155-157"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142765657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Redescription and new geographic distribution record of Dactylogyrus pharyngocephalus (Monogenea: Dactylogyridae) from tank goby Glossogobius giuris (Gobiidae, Teleostei) in Mizoram, northeast India.","authors":"Sneha Prakash, Amit K Trivedi, Amit Tripathi","doi":"10.17420/ap7001.519","DOIUrl":"https://doi.org/10.17420/ap7001.519","url":null,"abstract":"<p><p>Dactylogyrus pharyngocephalus is a dactylogyrid monogenean parasite originally described by Kulkarni, 1970 from tank goby Glossogobius giuris (Hamilton, 1822) in South India. The species has not been recorded since then. Fresh specimens of D. pharyngocephalus were collected from northeast India and examined morpho-molecularly. Temporary (glycerine mounted) and permanent (stained with Gomori's trichrome and DPX mounted) slides were made and photographed. Primer set C1 and D2 was employed to amplify a fragment of the 28S rRNA gene. The resulting nucleotide sequences, when examined by the BLAST tool, did not show 100% homology with any of the sequences deposited in GenBank. Based on new morpho-molecular data, the description of D. pharyngocephalus is revised, including the first description of its ventral bar.</p>","PeriodicalId":7987,"journal":{"name":"Annals of parasitology","volume":"70 1","pages":"35-40"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142674963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The topics of the sixty annual meetings \"Clinical Days of Medical Parasitology\" (CDMP) Medical University of Lodz.","authors":"Anna Wójcik, Piotr Kurnatowski","doi":"10.17420/ap7001.520","DOIUrl":"https://doi.org/10.17420/ap7001.520","url":null,"abstract":"","PeriodicalId":7987,"journal":{"name":"Annals of parasitology","volume":"70 1","pages":"51-54"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142674965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jozef Oboňa, Katarína Fogašová, Peter Krišovský, Laura Mlynárová, Bożena Sikora, Martin Hromada
{"title":"The first report of human biting by Lipoptena cervi from Slovakia.","authors":"Jozef Oboňa, Katarína Fogašová, Peter Krišovský, Laura Mlynárová, Bożena Sikora, Martin Hromada","doi":"10.17420/ap7001.516","DOIUrl":"10.17420/ap7001.516","url":null,"abstract":"<p><p>The first bite by deer ked Lipoptena cervi (Linnaeus, 1758) on humans has been reported from Slovakia. The host was bitten on the head and neck. Pain and itching appeared immediately after the bite. The skin lesion persisted for several weeks. Although the first documented case of human stings is published here, bites may have occurred in the past, albeit rarely.</p>","PeriodicalId":7987,"journal":{"name":"Annals of parasitology","volume":"70 ","pages":"47-49"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140856310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"In vitro efficacy of different concentrations of lupeol on old world Leishmania donovani.","authors":"Talib F Abbas, Ali Hayder Z","doi":"10.17420/ap7002.523","DOIUrl":"10.17420/ap7002.523","url":null,"abstract":"<p><p>Leishmaniosis is a tropical neglected parasitic disease that is endemic in many countries, including Middle East, with no existing effective vaccines. The bite of female sand-fly transmits the causative agent, Leishmania spp., to humans. High toxicity, resistance and treatment failure of the available chemotherapy against visceral leishmaniosis demands the investigation of new anti-leishmanial compounds. Lupeol is a form of triterpene isolated from several medicinal plants and possesses an antimicrobial property. In this study, cytotoxic effect of lupeol was screened against the mammalian amastigotes form and insect promastigote form of Leishmania donovani, following three cycles of incubation at different concentrations by MTT assay. Results revealed the in vitro anti-leishmanial effect of lupeol on both forms of the parasite where significant decline in promastigotes and amastigotes growth was observed. This was conducted along three times of follow up (24, 48, 72) hours, in comparison to the classical sodium stibogluconate treatment. Cell viability was calculated and the minimum IC50 was detected after 48 hours for amastigotes and 24 hours for promastigotes, 12.125 μM, 102.78 μM, respectively. Given the severity of visceral leishmaniosis and the toxicity of conventional chemotherapies, the anti-leishmanial activity of lupeol suggested a promising compound for additional clinical trials.</p>","PeriodicalId":7987,"journal":{"name":"Annals of parasitology","volume":"70 2","pages":"73-79"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141750858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abibatou Konate-Toure, Valérie A Bedia-Tanoh, Fulgence K Kassi, Henriette Vanga-Bosson, Etienne K Angora, Estelle G M Kone, Sebastien A J Miezan, Vincent Djohan, Pulcherie C M Barro-Kiki, Hervé E I Menan, William Yavo
{"title":"Assessment of the performance of five malaria rapid diagnostic tests in health facilities in Abidjan (Côte d'Ivoire).","authors":"Abibatou Konate-Toure, Valérie A Bedia-Tanoh, Fulgence K Kassi, Henriette Vanga-Bosson, Etienne K Angora, Estelle G M Kone, Sebastien A J Miezan, Vincent Djohan, Pulcherie C M Barro-Kiki, Hervé E I Menan, William Yavo","doi":"10.17420/ap7002.525","DOIUrl":"https://doi.org/10.17420/ap7002.525","url":null,"abstract":"<p><p>Regular monitoring of malaria rapid diagnostic tests (RDTs) for the management of uncomplicated malaria in healthcare facilities is a key factor in improving diagnostic quality and ensuring better case management. This study aimed to assess the performance of five RDTs (Standard Q Malaria P.f Ag and Standard Q Malaria P.f/Pan (SD Biosensor, Korea), One Step Malaria HRP2/pLDH (P.f/Pan) (Guangzhou Wondfo Biotech Co., Ltd., China), Malaria Pf/Pan (B&O Pharm, France), and Malaria test P.f/pan (Das Labor, Germany)) in two healthcare facilities in Abidjan. This cross-sectional study was conducted between September and October 2022. Overall, 250 patients suffering from uncomplicated malaria were included with a predominance of female patients (56.6%). The mean age was 22.3 years (SD = 20.6; range, 0.17-73). Of the patients tested, forty-six (46) tested positive for thick smears, reflecting a prevalence of 18.5%. Plasmodium falciparum was the most commonly detected species (93.5%). The geometric mean parasitemia was 6,111.80 parasites/μl (SD = 80,026.93) (range: 116-412461). The sensitivity ranged from 95.24% to 95.65%, whereas the specificity ranged from 93.07 to 94.09% for all five tests evaluated. The false positive rate of the tests was less than 10%. No invalid test results were reported. Two-thirds of P. malariae cases detected by microscopy showed also positive results with all the RDTs. All five RDTs showed 100% sensitivity at low parasitemia levels (< 1,000 parasites/μl blood) including three cases of parasites < 200 parasites/μl blood. This study demonstrated the importance of monitoring the performance of RDTs in clinical samples.</p>","PeriodicalId":7987,"journal":{"name":"Annals of parasitology","volume":"70 2","pages":"81-90"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141970499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}