Annals of Gastroenterology最新文献

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Use of N-acetylcysteine plus simethicone to improve mucosal visibility in upper digestive endoscopy via systematic alphanumeric-coded endoscopy: a randomized, double-blind controlled trial. 通过系统字母数字编码内窥镜检查,使用 N-乙酰半胱氨酸加西甲硅油改善上消化道内窥镜检查中的粘膜可见度:随机双盲对照试验。
IF 2.1
Annals of Gastroenterology Pub Date : 2024-07-01 Epub Date: 2024-06-14 DOI: 10.20524/aog.2024.0895
Sergio Sobrino-Cossío, Fabian Emura, Oscar Teramoto-Matsubara, Raúl Araya, Adolfo Parra-Blanco, Jonathan Richard White, Vitor Arantes, Josué Aliaga Ramos, Elymir Soraya Galvis-García, Francisco de-la-Vega-González, Gonzalo Rodríguez-Vanegas, Carlos Alberto Donneys, Arturo Reding-Bernal, Estrella Martínez-López, Juan Carlos López-Alvarenga, Noriya Uedo
{"title":"Use of N-acetylcysteine plus simethicone to improve mucosal visibility in upper digestive endoscopy via systematic alphanumeric-coded endoscopy: a randomized, double-blind controlled trial.","authors":"Sergio Sobrino-Cossío, Fabian Emura, Oscar Teramoto-Matsubara, Raúl Araya, Adolfo Parra-Blanco, Jonathan Richard White, Vitor Arantes, Josué Aliaga Ramos, Elymir Soraya Galvis-García, Francisco de-la-Vega-González, Gonzalo Rodríguez-Vanegas, Carlos Alberto Donneys, Arturo Reding-Bernal, Estrella Martínez-López, Juan Carlos López-Alvarenga, Noriya Uedo","doi":"10.20524/aog.2024.0895","DOIUrl":"10.20524/aog.2024.0895","url":null,"abstract":"<p><strong>Background: </strong>The use of antifoaming and mucolytic agents prior to upper gastrointestinal (GI) endoscopy and a thorough systematic review are essential to optimize lesion detection. This study evaluated the effect of simethicone and N-acetylcysteine on the adequate mucosal visibility (AMV) of the upper GI tract by an innovative systematic method.</p><p><strong>Methods: </strong>This randomized, double-blind controlled trial included consecutive patients who underwent diagnostic upper GI endoscopy for screening for early neoplasms between August 2019 and December 2019. The upper GI tract was systematically assessed by systematic alphanumeric-coded endoscopy. Patients were divided into 4 groups: 1) water; 2) only simethicone; 3) N-acetylcysteine + simethicone; and 4) only N-acetylcysteine. The following parameters were assessed in each group: age, sex, body mass index, level of adequate mucosal visibility, and side-effects.</p><p><strong>Results: </strong>A total of 4564 images from upper GI areas were obtained for evaluation. The mean AMV in the 4 groups was 93.98±7.36%. The N-acetylcysteine + simethicone group had a higher cleaning percentage compared with the other groups (P=0.001). There was no significant difference among the remaining groups, but several areas had better cleaning when a mucolytic or antifoam alone was used. No side-effects were found in any group.</p><p><strong>Conclusion: </strong>The combination of N-acetylcysteine plus simethicone optimizes the visibility of the mucosa of the upper GI tract, which could potentially increase diagnostic yield.</p>","PeriodicalId":7978,"journal":{"name":"Annals of Gastroenterology","volume":"37 4","pages":"410-417"},"PeriodicalIF":2.1,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11226743/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141554092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Frailty is a predictor for worse outcomes in patients hospitalized with Clostridioides difficile infection. 虚弱是艰难梭菌感染住院患者病情恶化的预测因素。
IF 2.1
Annals of Gastroenterology Pub Date : 2024-07-01 Epub Date: 2024-06-20 DOI: 10.20524/aog.2024.0898
Abdelkader Chaar, Jin Woo Yoo, Ahmad Nawaz, Rabia Rizwan, Osama Qasim Agha, Paul Feuerstadt
{"title":"Frailty is a predictor for worse outcomes in patients hospitalized with <i>Clostridioides difficile</i> infection.","authors":"Abdelkader Chaar, Jin Woo Yoo, Ahmad Nawaz, Rabia Rizwan, Osama Qasim Agha, Paul Feuerstadt","doi":"10.20524/aog.2024.0898","DOIUrl":"10.20524/aog.2024.0898","url":null,"abstract":"<p><strong>Background: </strong>Frailty has major health implications for affected patients and is widely used in the perioperative risk assessment. The Hospital Frailty Risk Score (HFRS) is a validated score that utilizes administrative billing data to identify patients at higher risk because of frailty. We investigated the utility of the HFRS in patients with <i>Clostridioides difficile</i> infection (CDI) to determine whether they were at risk for worse outcomes and higher healthcare resource utilization.</p><p><strong>Methods: </strong>Using the 2017 National Inpatient Sample, we identified all adults with a primary diagnosis of CDI. We classified patients into 2 groups: those who had an HFRS <5 (NonFrailCDI) and those with a score ≥5 (FrailCDI). We assessed differences in hospital outcomes and healthcare resource utilization based on frailty status.</p><p><strong>Results: </strong>We identified 93,810 hospitalizations, of which 54,300 (57.88%) were FrailCDI. FrailCDI patients were at higher risk for fulminant CDI (odds ratio [OR] 1.9, 95% confidence interval [CI] 1.6-2.3), requiring colectomy (OR 4.1, 95%CI 1.5-11.2), and inpatient mortality (OR 4.5, 95%CI 2.8-7.1). Furthermore, FrailCDI patients had higher odds of requiring Intensive Care Unit admission (OR 13.7, 95%CI 6.3-29.9) or transfer to another facility on discharge (OR 2.2, 95%CI 2.0-2.4), and had longer hospital stays and higher total charges when compared with NonFrailCDI.</p><p><strong>Conclusions: </strong>Frailty as defined by the HFRS is an independent factor for worse outcomes and higher healthcare utilization in adults admitted for CDI. Risk stratifying patients by frailty may improve outcomes.</p>","PeriodicalId":7978,"journal":{"name":"Annals of Gastroenterology","volume":"37 4","pages":"442-448"},"PeriodicalIF":2.1,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11226747/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141554084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical characteristics of symptomatic young patients with colonic adenomas. 有症状的年轻结肠腺瘤患者的临床特征。
IF 2.2
Annals of Gastroenterology Pub Date : 2024-05-01 Epub Date: 2024-03-20 DOI: 10.20524/aog.2024.0872
Mario El Hayek, Fadi F Francis, Fadi H Mourad, Martine Elbejjani, Kassem Barada, Jana G Hashash
{"title":"Clinical characteristics of symptomatic young patients with colonic adenomas.","authors":"Mario El Hayek, Fadi F Francis, Fadi H Mourad, Martine Elbejjani, Kassem Barada, Jana G Hashash","doi":"10.20524/aog.2024.0872","DOIUrl":"10.20524/aog.2024.0872","url":null,"abstract":"<p><strong>Background: </strong>The incidence of colonic adenomas and colorectal cancer has been on the rise among young patients. In this study, we aimed to describe the characteristics of young patients (<50 years) with adenomatous polyps and to characterize those polyps. We also aimed to determine appropriate surveillance intervals for young patients.</p><p><strong>Methods: </strong>We performed a retrospective chart review of patients <50 years of age who had polypectomy of 1 or more adenomatous polyps on colonoscopy between 2008 and 2021. Patient demographics, colonoscopy indication and polyp characteristics were obtained from the chart. Timing and findings on surveillance colonoscopies were recorded.</p><p><strong>Results: </strong>A total of 610 patients were included: mean age 42.9±5.9 years, 61% males, body mass index 27.5±4.7 kg/m<sup>2</sup>, and over 50% smokers. The most common indications were abdominal pain (23.3%), rectal bleeding (22.3%), and change in bowel habits (17.6%). Almost half of the patients who had adenomas (299) were younger than 45 years. Tubular adenoma was the most frequently encountered type of polyp (571; 93.6%). Mean polyp size was 1.1±0.9 cm. The most common location of adenomas was the sigmoid colon (41%). Of patients with adenomas, 156 (26%) had surveillance colonoscopy within 2.9±2.3 years; 74 patients (47.4%) were found to have new adenomas.</p><p><strong>Conclusions: </strong>Patients aged <50 years with colonic adenomas were mostly males, overweight, and smokers. Further adenomas were found in 47% of surveillance colonoscopies, and most were encountered within 5 years. High rates of recurrent adenomas in people <50 years of age may warrant frequent surveillance.</p>","PeriodicalId":7978,"journal":{"name":"Annals of Gastroenterology","volume":"37 3","pages":"341-347"},"PeriodicalIF":2.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11107410/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141080529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pre-left ventricular assist device endoscopic evaluation does not reduce the risk of later gastrointestinal bleeding: a multicenter study. 左心室辅助装置前内窥镜评估不会降低日后消化道出血的风险:一项多中心研究。
IF 2.2
Annals of Gastroenterology Pub Date : 2024-05-01 Epub Date: 2024-04-10 DOI: 10.20524/aog.2024.0878
Jiahao Peng, Samanthika Devalaraju, Mohamed Azab, William T Cates, Molly Stone, Jonathan Reichstein, Sneha Shaha, Subhasis Chatterjee, Andrew B Civitello, Mourad H Senussi, B Joseph Elmunzer, Michael Volk, Wasseem Skef
{"title":"Pre-left ventricular assist device endoscopic evaluation does not reduce the risk of later gastrointestinal bleeding: a multicenter study.","authors":"Jiahao Peng, Samanthika Devalaraju, Mohamed Azab, William T Cates, Molly Stone, Jonathan Reichstein, Sneha Shaha, Subhasis Chatterjee, Andrew B Civitello, Mourad H Senussi, B Joseph Elmunzer, Michael Volk, Wasseem Skef","doi":"10.20524/aog.2024.0878","DOIUrl":"10.20524/aog.2024.0878","url":null,"abstract":"<p><strong>Background: </strong>Gastrointestinal bleeding (GIB) is a common complication after placement of a left ventricular assist device (LVAD). Some institutions attempt to mitigate post-LVAD GIB using preoperative endoscopy. Our study evaluated whether preoperative endoscopy was associated with a lower risk of post-LVAD GIB.</p><p><strong>Methods: </strong>This was a multicenter cohort study of patients who underwent LVAD insertion from 2010-2019 at 3 academic sites. A total of 398 study participants were categorized based on whether they underwent preoperative endoscopy or not. The follow-up period was 1 year and the primary outcome was GIB. Secondary outcomes were severe bleeding and intraprocedural complications.</p><p><strong>Results: </strong>A total of 114 patients experienced GIB within 1 year, with a higher rate in the endoscopy cohort (36.4% vs. 24.8%, P=0.015). After adjusting for covariables, the endoscopy cohort remained at increased risk of GIB (adjusted odds ratio 1.77, 95% confidence interval 1.05-2.976; P=0.032). Severe bleeding was common (47.4%). Arteriovenous malformations (48 cases) and peptic ulcer disease (17 cases) were the most identified sources of GIB. Only 1 minor adverse event occurred during preoperative endoscopy.</p><p><strong>Conclusions: </strong>Our study suggests that pre-LVAD endoscopy is associated with a higher risk of GIB post LVAD, despite controlling for confounders. While this was an observational study and may not have captured all confounders, it appears that endoscopic screening may not be warranted.</p>","PeriodicalId":7978,"journal":{"name":"Annals of Gastroenterology","volume":"37 3","pages":"313-320"},"PeriodicalIF":2.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11107400/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141080556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Update in preventing post-endoscopic retrograde cholangiopancreatography pancreatitis. 预防内镜逆行胰胆管造影术后胰腺炎的最新进展。
IF 2.2
Annals of Gastroenterology Pub Date : 2024-05-01 Epub Date: 2024-03-14 DOI: 10.20524/aog.2024.0870
Bálint Gellért, Árpád V Patai, István Hritz
{"title":"Update in preventing post-endoscopic retrograde cholangiopancreatography pancreatitis.","authors":"Bálint Gellért, Árpád V Patai, István Hritz","doi":"10.20524/aog.2024.0870","DOIUrl":"10.20524/aog.2024.0870","url":null,"abstract":"<p><p>Of all the possible complications associated with endoscopic retrograde cholangiopancreatography (ERCP), acute pancreatitis undoubtedly represents the heaviest burden for patients and healthcare professionals. The overall incidence, ranging from 3.5% to around 10%, and annual estimated costs exceeding $150 million in the USA should signal caution for everyone carrying out ERCP. In-depth knowledge of the risk factors and the pharmacological and endoscopic treatment options is required to avoid this adverse event. In this review, we evaluate the relevant data published in the literature since the appearance of the latest recommendations of the leading gastroenterological societies. Thus, we intend to provide a comprehensive and up-to-date overview of the factors to consider and possible interventions applicable before and after the intervention to prevent the development of post-ERCP pancreatitis.</p>","PeriodicalId":7978,"journal":{"name":"Annals of Gastroenterology","volume":"37 3","pages":"266-279"},"PeriodicalIF":2.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11107403/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141080557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of the diagnostic yield of rapid versus non-rapid onsite evaluation in endoscopic ultrasound-guided fine-needle aspiration cytology of solid pancreatic lesions. 内镜超声引导下胰腺实体病变细针穿刺细胞学快速与非快速现场评估诊断率的比较。
IF 2.2
Annals of Gastroenterology Pub Date : 2024-05-01 Epub Date: 2024-04-22 DOI: 10.20524/aog.2024.0879
Rajeeb Jaleel, John Titus George, Ajith Thomas, Lalji Patel, Anoop John, Reuben Thomas Kurien, Ebby George Simon, A J Joseph, Amit Kumar Dutta, Sudipta Dhar Chowdhury
{"title":"Comparison of the diagnostic yield of rapid versus non-rapid onsite evaluation in endoscopic ultrasound-guided fine-needle aspiration cytology of solid pancreatic lesions.","authors":"Rajeeb Jaleel, John Titus George, Ajith Thomas, Lalji Patel, Anoop John, Reuben Thomas Kurien, Ebby George Simon, A J Joseph, Amit Kumar Dutta, Sudipta Dhar Chowdhury","doi":"10.20524/aog.2024.0879","DOIUrl":"10.20524/aog.2024.0879","url":null,"abstract":"<p><strong>Background: </strong>The role of rapid on-site evaluation (ROSE) for endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) of pancreatic lesions is debatable. In this study, we aimed to compare the diagnostic yield of ROSE vs. non-ROSE in solid pancreatic lesions.</p><p><strong>Methods: </strong>This retrospective single-center study included patients undergoing EUS-FNA of solid pancreatic lesions from 2019-2021. Patients with cystic lesions, those undergoing fine-needle core biopsy, those undergoing repeat procedures, and patients with non-diagnostic smears with less than 6-month follow up were excluded. The diagnostic yield, need for repeat procedures and number of passes required with and without ROSE were analyzed in these patients.</p><p><strong>Results: </strong>Of the 111 patients included, 56 underwent ROSE. The majority of lesions were malignant in both groups (79.6% ROSE vs. 75% non-ROSE). The diagnostic yield was 96.4% in the ROSE group and 94.5% in the non-ROSE group. Repeat samples were needed in 1 ROSE and 2 non-ROSE patients. The median number of passes made was significantly fewer in the ROSE group (3.5, interquartile range - 3,4) compared with the non-ROSE group (4, interquartile range - 3,5) P=0.01. However, the frequency of procedure-related complications was similar in both groups.</p><p><strong>Conclusion: </strong>The utilization of ROSE during EUS-FNA of solid pancreatic lesions does not affect the diagnostic yield or the need for repeat samples, but reduces the number of passes needed for acquiring samples.</p>","PeriodicalId":7978,"journal":{"name":"Annals of Gastroenterology","volume":"37 3","pages":"371-376"},"PeriodicalIF":2.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11107408/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141080575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endoscopic ultrasound-guided portal pressure gradient measurement: a systematic review and meta-analysis. 内窥镜超声引导下的门静脉压力梯度测量:系统综述和荟萃分析。
IF 2.2
Annals of Gastroenterology Pub Date : 2024-05-01 Epub Date: 2024-04-29 DOI: 10.20524/aog.2024.0882
Banreet Singh Dhindsa, Kyaw Min Tun, Alexandra Fiedler, Smit Deliwala, Syed Mohsin Saghir, Kyle Scholten, Daryl Ramai, Mohit Girotra, Saurabh Chandan, Amaninder Dhaliwal, Ishfaq Bhat, Shailender Singh, Douglas G Adler
{"title":"Endoscopic ultrasound-guided portal pressure gradient measurement: a systematic review and meta-analysis.","authors":"Banreet Singh Dhindsa, Kyaw Min Tun, Alexandra Fiedler, Smit Deliwala, Syed Mohsin Saghir, Kyle Scholten, Daryl Ramai, Mohit Girotra, Saurabh Chandan, Amaninder Dhaliwal, Ishfaq Bhat, Shailender Singh, Douglas G Adler","doi":"10.20524/aog.2024.0882","DOIUrl":"10.20524/aog.2024.0882","url":null,"abstract":"<p><strong>Background: </strong>Endoscopic ultrasound-guided portal pressure gradient measurement (EUS-PPG) is a new modality where the portal pressure is measured by directly introducing a needle into the hepatic vein and portal vein. This is the first systematic review and meta-analysis to evaluate the efficacy and safety of EUS-PPG.</p><p><strong>Methods: </strong>A comprehensive literature search was performed to identify pertinent studies. The primary outcomes assessed were the technical and clinical success of EUS-PPG. Technical success was defined as successful introduction of the needle into the desired vessel, while clinical success was defined as the correlation of the stage of fibrosis on the liver biopsy to EUS-PPG, or concordance of HVPG and EUS-PPG. The secondary outcomes were pooled rates for total and individual adverse events related to EUS-PPG. Pooled estimates were calculated using random-effects models with a 95% confidence interval (CI).</p><p><strong>Results: </strong>Eight cohort studies with a total of 178 patients were included in our analysis. The calculated pooled rates of technical success and clinical success were 94.6% (95%CI 88.5-97.6%; P=<0.001; <i>I</i><sup>2</sup>=0) and 85.4% (95%CI 51.5-97.0%; P=0.042; <i>I</i><sup>2</sup>=70), respectively. The rate of total adverse events was 10.9% (95%CI 6.5-17.7%; P=<0.001; <i>I</i><sup>2</sup>=4), and 93.7% of them were mild, as defined by the American Society for Gastrointestinal Endoscopy. Abdominal pain (11%) was the most common adverse event, followed by bleeding (3.6%). There were no cases of perforation or death reported in our study.</p><p><strong>Conclusions: </strong>EUS-PPG is a safe and effective modality for diagnosing portal hypertension. Further randomized controlled trials are needed to validate our findings.</p>","PeriodicalId":7978,"journal":{"name":"Annals of Gastroenterology","volume":"37 3","pages":"356-361"},"PeriodicalIF":2.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11107402/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141080585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of preoperative workup and comorbidities with risk of gastroesophageal surgery failure. 术前检查和合并症与胃食管手术失败风险的关系。
IF 2.2
Annals of Gastroenterology Pub Date : 2024-05-01 Epub Date: 2024-04-06 DOI: 10.20524/aog.2024.0874
Frank Ventura, Rohin Gawdi, Zach German, Ana Patel, Carl Westcott, Steven Clayton
{"title":"Association of preoperative workup and comorbidities with risk of gastroesophageal surgery failure.","authors":"Frank Ventura, Rohin Gawdi, Zach German, Ana Patel, Carl Westcott, Steven Clayton","doi":"10.20524/aog.2024.0874","DOIUrl":"10.20524/aog.2024.0874","url":null,"abstract":"<p><strong>Background: </strong>While surgical failure rates for fundoplication and hiatal hernia repair are low, there has been no clear evaluation of the preoperative risk factors associated with surgical failure. This study aimed to identify risk factors predisposing patients to surgical failure.</p><p><strong>Methods: </strong>Patients who underwent antireflux surgery during a 3-year period were evaluated for evidence of surgical complications and placed accordingly into the failure or control group. Demographic data, comorbidities, clinical presentation, preoperative evaluation, and surgical data were collected and compared between the groups.</p><p><strong>Results: </strong>In total, 86 patients with failure and 42 controls were identified among our cohort. No significant differences were found between groups based on sex (P=0.640). However, patients with failure were younger than controls (57.0 vs. 64.7 years, P=0.0001). Body mass index, tobacco use and alcohol use did not differ significantly between the groups (P=0.189, P=0.0999, P=0.060). Notably, psychiatric illness was more common in the failure group (P=0.0086). Neither hypertension (P=0.134) nor diabetes (P=0.335) had significant differences between groups. For procedures, no significant differences were found for the frequencies of preoperative imaging (P=0.395) or manometry (P=0.374), but pH/BRAVO studies (P=0.0193) and endoscopy (P<0.001) were both performed more frequently in the failure group.</p><p><strong>Conclusions: </strong>Patients with psychiatric comorbidities are at higher risk of surgical failure. Alcohol use trended toward significance, which warrants further investigation. We also noted an increase in rates of preoperative pH and endoscopy studies, contrary to the prior literature; this is likely due to more complex cases requiring additional workup.</p>","PeriodicalId":7978,"journal":{"name":"Annals of Gastroenterology","volume":"37 3","pages":"321-326"},"PeriodicalIF":2.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11107399/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141080509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Complex cystic liver lesions: classification, diagnosis, and management. 复杂的肝脏囊性病变:分类、诊断和处理。
IF 2.2
Annals of Gastroenterology Pub Date : 2024-05-01 Epub Date: 2024-04-06 DOI: 10.20524/aog.2024.0876
Evangelos G Baltagiannis, Athina Tsili, Anna Goussia, Anastasia Glantzouni, Konstantinos Frigkas, Antonia Charchanti, Georgios K Glantzounis, Ilias P Gomatos
{"title":"Complex cystic liver lesions: classification, diagnosis, and management.","authors":"Evangelos G Baltagiannis, Athina Tsili, Anna Goussia, Anastasia Glantzouni, Konstantinos Frigkas, Antonia Charchanti, Georgios K Glantzounis, Ilias P Gomatos","doi":"10.20524/aog.2024.0876","DOIUrl":"10.20524/aog.2024.0876","url":null,"abstract":"<p><p>Cystic liver disease has been increasingly reported in the literature, with a prevalence as high as 15-18%. Hepatic cysts are usually discovered incidentally, while their characterization and classification rely on improved imaging modalities. Complex cystic liver lesions comprise a wide variety of novel, re-introduced, and re-classified clinical entities. This spectrum of disorders ranges from non-neoplastic conditions to benign and malignant tumors. Their clinicopathological features, prognostic factors, and oncogenic pathways are incompletely understood. Despite representing a heterogeneous group of disorders, they can have similar clinical and imaging characteristics. As a result, the diagnosis and management of complex liver cysts can become quite challenging. Furthermore, inappropriate diagnosis and management can lead to high morbidity and mortality. In this review, we aim to offer up-to-date insight into the diagnosis, classification, and management of the most common complex cystic liver lesions.</p>","PeriodicalId":7978,"journal":{"name":"Annals of Gastroenterology","volume":"37 3","pages":"255-265"},"PeriodicalIF":2.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11107409/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141080540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Disparities in postoperative outcomes among diverse patient groups with inflammatory bowel disease. 不同炎症性肠病患者群体术后效果的差异。
IF 2.2
Annals of Gastroenterology Pub Date : 2024-05-01 Epub Date: 2024-03-18 DOI: 10.20524/aog.2024.0871
Ashley Shustak, Luke Wolfe, Matthew Ambrosio, Stephen Sharp, Nicole Wieghard
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