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Proceedings : a conference of the American Medical Informatics Association. AMIA Fall Symposium最新文献

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Using data mining to characterize DNA mutations by patient clinical features. 利用数据挖掘根据患者临床特征来描述DNA突变。
Proceedings : a conference of the American Medical Informatics Association. AMIA Fall Symposium Pub Date : 1997-01-01
S Evans, S J Lemon, C Deters, R M Fusaro, C Durham, C Snyder, H T Lynch
{"title":"Using data mining to characterize DNA mutations by patient clinical features.","authors":"S Evans,&nbsp;S J Lemon,&nbsp;C Deters,&nbsp;R M Fusaro,&nbsp;C Durham,&nbsp;C Snyder,&nbsp;H T Lynch","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In most hereditary cancer syndromes, finding a correspondence between various genetic mutations within a gene (genotype) and a patient's clinical cancer history (phenotype) is challenging; to date there are few clinically meaningful correlations between specific DNA intragenic mutations and corresponding cancer types. To define possible genotype and phenotype correlations, we evaluated the application of data mining methodology whereby the clinical cancer histories of gene-mutation-positive patients were used to define valid or \"true\" patterns for a specific DNA intragenic mutation. The clinical histories of patients with their corresponding detailed attributes without the same oncologic intragenic mutation were labeled incorrect or \"false\" patterns. The results of data mining technology yielded characterizing rules for the true cases that constituted clinical features which predicted the intragenic mutation. Some of the initial results derived correlations already independently known in the literature, adding to the confidence of using this methodological approach.</p>","PeriodicalId":79455,"journal":{"name":"Proceedings : a conference of the American Medical Informatics Association. AMIA Fall Symposium","volume":" ","pages":"253-7"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233315/pdf/procamiaafs00001-0291.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20290675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A decision support system for microbiology quality control. 微生物质量控制决策支持系统。
Proceedings : a conference of the American Medical Informatics Association. AMIA Fall Symposium Pub Date : 1997-01-01
B R Jackson, J D Schwartzman, D E Zuaro, E K Shultz
{"title":"A decision support system for microbiology quality control.","authors":"B R Jackson,&nbsp;J D Schwartzman,&nbsp;D E Zuaro,&nbsp;E K Shultz","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Manual review of antibiotic sensitivity testing results is an essential component of a microbiology laboratory's quality control process. Such review is tedious and prone to human error, however. An expert system is described that remembers which susceptibility patterns are considered typical or atypical by expert reviewers, then uses these to prescreen future isolates. It uses a similarity function to allow matching against this library when two patterns are close, but not identical. Use of this system allows more efficient and reliable review of the laboratory's antibiotic sensitivity testing results.</p>","PeriodicalId":79455,"journal":{"name":"Proceedings : a conference of the American Medical Informatics Association. AMIA Fall Symposium","volume":" ","pages":"258-62"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233334/pdf/procamiaafs00001-0296.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20290676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patient-Centered Access to Secure Systems Online (PCASSO): a secure approach to clinical data access via the World Wide Web. 以患者为中心的安全在线系统访问(PCASSO):通过万维网访问临床数据的安全方法。
Proceedings : a conference of the American Medical Informatics Association. AMIA Fall Symposium Pub Date : 1997-01-01
D R Masys, D B Baker
{"title":"Patient-Centered Access to Secure Systems Online (PCASSO): a secure approach to clinical data access via the World Wide Web.","authors":"D R Masys,&nbsp;D B Baker","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The Internet's World-Wide Web (WWW) provides an appealing medium for the communication of health related information due to its ease of use and growing popularity. But current technologies for communicating data between WWW clients and servers are systematically vulnerable to certain types of security threats. Prominent among these threats are \"Trojan horse\" programs running on client workstations, which perform some useful and known function for a user, while breaching security via background functions that are not apparent to the user. The Patient-Centered Access to Secure Systems Online (PCASSO) project of SAIC and UCSD is a research, development and evaluation project to exploit state-of-the-art security and WWW technology for health care. PCASSO is designed to provide secure access to clinical data for healthcare providers and their patients using the Internet. PCASSO will be evaluated for both safety and effectiveness, and may provide a model for secure communications via public data networks.</p>","PeriodicalId":79455,"journal":{"name":"Proceedings : a conference of the American Medical Informatics Association. AMIA Fall Symposium","volume":" ","pages":"340-3"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233557/pdf/procamiaafs00001-0377.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20287528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Searching for information on the Internet using the UMLS and Medical World Search. 使用UMLS和医学世界搜索在Internet上搜索信息。
Proceedings : a conference of the American Medical Informatics Association. AMIA Fall Symposium Pub Date : 1997-01-01
H H Suarez, X Hao, I F Chang
{"title":"Searching for information on the Internet using the UMLS and Medical World Search.","authors":"H H Suarez,&nbsp;X Hao,&nbsp;I F Chang","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Medical World Search is a search engine for medical information on the Internet that distinguishes itself from other search engines by its built-in knowledge of medical terminology through its use of the National Library of Medicine's UMLS and its carefully selected but large database of medical sites. After discussing some of the previous uses of the UMLS for medical information retrieval, we describe the Medical World Search system. In October 1996, Medical World Search became operational on the World Wide Web at http:@www.mwsearch.poly.edu. It has been operating uninterrupted since then. We review our experiences with creating a search engine for medical information on the Internet and using the UMLS in this application. The UMLS has some clear advantages in this application. Some aspects of the UMLS also decrease its usefulness in information retrieval. Medical World Search's usage by medical information seekers is summarized. future directions for research are outlined.</p>","PeriodicalId":79455,"journal":{"name":"Proceedings : a conference of the American Medical Informatics Association. AMIA Fall Symposium","volume":" ","pages":"824-8"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233554/pdf/procamiaafs00001-0858.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20287537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An expert-guided decision tree construction strategy: an application in knowledge discovery with medical databases. 专家指导决策树构建策略在医学数据库知识发现中的应用。
Proceedings : a conference of the American Medical Informatics Association. AMIA Fall Symposium Pub Date : 1997-01-01
Y S Tsai, P H King, M S Higgins, D Pierce, N P Patel
{"title":"An expert-guided decision tree construction strategy: an application in knowledge discovery with medical databases.","authors":"Y S Tsai,&nbsp;P H King,&nbsp;M S Higgins,&nbsp;D Pierce,&nbsp;N P Patel","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>With the steady growth in electronic patient records and clinical medical informatics systems, the data collected for routine clinical use have been accumulating at a dramatic rate. Inter-disciplinary research provides a new generation of computation tools in knowledge discovery and data management is in great demand. In this study, an expert-guided decision tree construction strategy is proposed to offer an user-oriented knowledge discovery environment. The strategy allows experts, based on their expertise and/or preference, to override inductive decision tree construction process. Moreover, by reviewing decision paths, experts could focus on subsets of data that may be clues to new findings, or simply contaminated cases.</p>","PeriodicalId":79455,"journal":{"name":"Proceedings : a conference of the American Medical Informatics Association. AMIA Fall Symposium","volume":" ","pages":"208-12"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233397/pdf/procamiaafs00001-0246.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20287857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cross-institutional reuse of a problem statement knowledge base. 问题陈述知识库的跨机构重用。
Proceedings : a conference of the American Medical Informatics Association. AMIA Fall Symposium Pub Date : 1997-01-01
S H Brown, D A Giuse
{"title":"Cross-institutional reuse of a problem statement knowledge base.","authors":"S H Brown,&nbsp;D A Giuse","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This article describes client and server applications for a problem statement knowledge base derived from a large corpus of provider entered terminology. The current status and potential for integration of the server into the Vanderbilt University Medical Center computing environment are discussed. Finally, an experiment in multiple dimensions of reuse for problem list terms is introduced, and possible strategies to mediate between free text and coded data are examined.</p>","PeriodicalId":79455,"journal":{"name":"Proceedings : a conference of the American Medical Informatics Association. AMIA Fall Symposium","volume":" ","pages":"151-5"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233559/pdf/procamiaafs00001-0190.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20288525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Structuring clinical practice guidelines in a relational database model for decision support on the Internet. 在因特网决策支持的关系数据库模型中构建临床实践指南。
Proceedings : a conference of the American Medical Informatics Association. AMIA Fall Symposium Pub Date : 1997-01-01
D F Lobach, C S Gadd, J W Hales
{"title":"Structuring clinical practice guidelines in a relational database model for decision support on the Internet.","authors":"D F Lobach,&nbsp;C S Gadd,&nbsp;J W Hales","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The rapid proliferation of clinical practice guidelines (CPGs) has made computerization increasingly useful to clinicians. Computerization, however, requires transformation of the content and logic of each guideline into a computer-accessible form. In this project, we sought to use a relational database to construct a generalized guideline knowledge base for use with Internet-based decision support applications. We hypothesized that knowledge representation schemes could be developed to capture guideline content and logic within the constraints of a relational database model. In this paper we describe a database schema based on a relational model for computerizing CPGs using a hybrid of structured and procedural knowledge representation schemes. We developed and refined this model in the context of five diverse CPGs and found it accommodated all necessary representational requirements.</p>","PeriodicalId":79455,"journal":{"name":"Proceedings : a conference of the American Medical Informatics Association. AMIA Fall Symposium","volume":" ","pages":"158-62"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233577/pdf/procamiaafs00001-0196.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20288526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Towards a comprehensive medical language processing system: methods and issues. 迈向综合医学语言处理系统:方法与问题。
Proceedings : a conference of the American Medical Informatics Association. AMIA Fall Symposium Pub Date : 1997-01-01
C Friedman
{"title":"Towards a comprehensive medical language processing system: methods and issues.","authors":"C Friedman","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Natural language processing (NLP) systems can help solve the data entry problem by providing coded data from textual reports for clinical applications. A number of NLP systems have shown promise, but have not yet achieved wide-spread use for practical applications. In order to achieve such use, a system must have broad coverage of the clinical domain and not be restricted to limited applications. In addition, an NLP system must perform satisfactorily for real-world applications. This paper describes methods and issues associated with an ongoing extension of MedLEE, an operational NLP system, from a limited domain to a domain that encompasses comprehensive clinical information.</p>","PeriodicalId":79455,"journal":{"name":"Proceedings : a conference of the American Medical Informatics Association. AMIA Fall Symposium","volume":" ","pages":"595-9"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233560/pdf/procamiaafs00001-0630.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20288537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Terminological systems: bridging the generation gap. 术语系统:弥合代沟。
Proceedings : a conference of the American Medical Informatics Association. AMIA Fall Symposium Pub Date : 1997-01-01
J E Rogers, A L Rector
{"title":"Terminological systems: bridging the generation gap.","authors":"J E Rogers,&nbsp;A L Rector","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A rigorous formal description of the intended behaviour of a compositional terminology, a 'third generation' system, enables powerful semantic processing techniques to assist in the building of a large terminology. Use of an intermediate representation derived from such a formalism, but simplified to resemble a 'second generation' system, enables authors to work in an simpler and more familiar environment, avoiding many of the technical complications of the 'third generation' system.</p>","PeriodicalId":79455,"journal":{"name":"Proceedings : a conference of the American Medical Informatics Association. AMIA Fall Symposium","volume":" ","pages":"610-4"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233580/pdf/procamiaafs00001-0645.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20288540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical care management and workflow by episodes. 临床护理管理和工作流程的发作。
Proceedings : a conference of the American Medical Informatics Association. AMIA Fall Symposium Pub Date : 1997-01-01
P L Claus, P C Carpenter, C G Chute, D N Mohr, P S Gibbons
{"title":"Clinical care management and workflow by episodes.","authors":"P L Claus,&nbsp;P C Carpenter,&nbsp;C G Chute,&nbsp;D N Mohr,&nbsp;P S Gibbons","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This paper describes the implementation of clinically defined episodes of care and the introduction of an episode-based summary list of patient problems across Mayo Clinic Rochester in 1996 and 1997. Although Mayo's traditional paper-based system has always relied on a type of 'episode of care' (called the \"registration\") for patient and history management, a new, more clinically relevant definition of episode of care was put into practice in November 1996. This was done to improve care management and operational processes and to provide a basic construct for the electronic medical record. Also since November 1996, a computer-generated summary list of patient problems, the \"Master Sheet Summary Report,\" organized by episode, has been placed in all patient histories. In the third quarter of 1997, the ability to view the episode-based problem summary online was made available to the 3000+ EMR-capable workstations deployed across the Mayo Rochester campus. In addition, the clinically oriented problem summarization process produces an improved basic \"package\" of clinical information expected to lead to improved analytic decision support, outcomes analysis and epidemiological research.</p>","PeriodicalId":79455,"journal":{"name":"Proceedings : a conference of the American Medical Informatics Association. AMIA Fall Symposium","volume":" ","pages":"91-5"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233562/pdf/procamiaafs00001-0130.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20288593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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