Annals of Internal Medicine最新文献

{"title":"Depressive and Anxiety Symptoms in U.S. Adults With Type 1 Diabetes.","authors":"Tianyu Cao, Dan Wang, Justin B Echouffo-Tcheugui, Jung-Im Shin, Elizabeth Selvin, Michael Fang","doi":"10.7326/ANNALS-26-01948","DOIUrl":"https://doi.org/10.7326/ANNALS-26-01948","url":null,"abstract":"","PeriodicalId":7932,"journal":{"name":"Annals of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":17.2,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149223126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: Temperature-Related Deaths in the United States, 1999 to 2024.","authors":"","doi":"10.7326/ANNALS-26-04188","DOIUrl":"https://doi.org/10.7326/ANNALS-26-04188","url":null,"abstract":"","PeriodicalId":7932,"journal":{"name":"Annals of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":17.2,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149223095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early Uptake of Oral Semaglutide for Obesity Treatment After Regulatory Approval.","authors":"Yara Jelwan, Sohail Zahid, Semenawit Burka, Nader Silver, Omar Dzaye, Michael J Blaha","doi":"10.7326/ANNALS-26-02436","DOIUrl":"https://doi.org/10.7326/ANNALS-26-02436","url":null,"abstract":"","PeriodicalId":7932,"journal":{"name":"Annals of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":17.2,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149164837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"What Simple Health Policy Models Reveal: Tradeoffs, Uncertainty, and Values.","authors":"A David Paltiel","doi":"10.7326/ANNALS-26-02824","DOIUrl":"10.7326/ANNALS-26-02824","url":null,"abstract":"","PeriodicalId":7932,"journal":{"name":"Annals of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":17.2,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149164689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Legal Battle Over Mifepristone and the Future of FDA Regulation.","authors":"S Sean Tu, Lewis A Grossman, William B Feldman","doi":"10.7326/ANNALS-26-03376","DOIUrl":"https://doi.org/10.7326/ANNALS-26-03376","url":null,"abstract":"","PeriodicalId":7932,"journal":{"name":"Annals of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":17.2,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149164627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New guidance brings attention to bronchiectasis.","authors":"Janet Colwell","doi":"10.7326/ANNALS-26-04202-IM","DOIUrl":"https://doi.org/10.7326/ANNALS-26-04202-IM","url":null,"abstract":"","PeriodicalId":7932,"journal":{"name":"Annals of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":17.2,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149164660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Out-of-Pocket Savings Among Medicare Part D Beneficiaries Under the Medicare Drug Price Negotiation Program.","authors":"Grace Castle, Jihye Han, Haiden A Huskamp, Nancy L Keating, Stacie B Dusetzina","doi":"10.7326/ANNALS-26-02703","DOIUrl":"https://doi.org/10.7326/ANNALS-26-02703","url":null,"abstract":"","PeriodicalId":7932,"journal":{"name":"Annals of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":17.2,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149164489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Benzodiazepine Use Early in Pregnancy and Risk for Congenital Malformations.","authors":"Kelly Fung, Ayesha C Sujan, Brian T Bateman, Loreen Straub, Sonia Hernandez-Diaz, Gregory Brill, Yanmin Zhu, Lee S Cohen, Kathryn J Gray, Krista F Huybrechts","doi":"10.7326/ANNALS-25-05148","DOIUrl":"https://doi.org/10.7326/ANNALS-25-05148","url":null,"abstract":"<p><strong>Background: </strong>Existing data on malformations associated with benzodiazepine use in pregnancy are conflicting.</p><p><strong>Objective: </strong>To assess the risk for major congenital malformations from first-trimester exposure to benzodiazepines.</p><p><strong>Design: </strong>Population-based U.S. cohort study.</p><p><strong>Setting: </strong>Medicaid (2000-2018) and Merative MarketScan (2003-2020) databases.</p><p><strong>Participants: </strong>Pregnant persons enrolled from 90 days before pregnancy to 30 days after delivery, and their live-born infants enrolled for 90 days after birth.</p><p><strong>Measurements: </strong>Exposure was defined as at least 1 fill of a benzodiazepine in the first trimester. Primary outcomes were any major congenital malformation and organ-specific malformations previously associated with benzodiazepine exposure. The investigators estimated relative risks (RRs) comparing exposed versus unexposed pregnancies with propensity score fine stratification weights to control for confounders. An RR of 1.3 or higher was prespecified as clinically significant.</p><p><strong>Results: </strong>In total, 51 339 of 2 478 434 (2.1%) publicly insured and 27 779 of 1 750 721 (1.6%) commercially insured pregnancies had benzodiazepine exposure. The adjusted absolute risks for any malformation in exposed versus unexposed pregnancies were 4.0% versus 4.1% for Medicaid and 4.9% versus 4.8% for MarketScan. The pooled adjusted RR was 0.99 (95% CI, 0.96 to 1.03). Associations with organ-specific malformations were not consistently observed in sensitivity analyses, nor was a dose-response relationship observed. Analyses of different benzodiazepines yielded similar results. The risk for selected organ-specific malformations was increased in some analyses of coexposure to benzodiazepines and other psychoactive medications, but a consistent pattern did not emerge.</p><p><strong>Limitations: </strong>Potential nondifferential exposure and outcome misclassification; analyses restricted to malformations prevalent at birth.</p><p><strong>Conclusion: </strong>No substantial increase in the risk for malformations was consistently identified across data sources. Findings from coexposure analyses were inconsistent and warrant further study.</p><p><strong>Primary funding source: </strong>National Institute of Child Health and Human Development.</p>","PeriodicalId":7932,"journal":{"name":"Annals of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":17.2,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149164835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Notice of Retraction and Republication: The Effect of Fluvoxamine and Metformin for Fatigue in Patients With Long COVID: An Adaptive Randomized Trial.","authors":"Gilmar Reis, Eduardo Augusto Dos Santos Moreira Silva, Daniela Carla Medeiros Silva, Lehana Thabane, Thiago Santiago Ferreira, Luiza Lanna França Reis, Ana Paula Figueiredo Guimaraes Almeida, Marcela Menezes Amaral, Leonardo Cançado Monteiro Savassi, Vitoria Helena de Souza Campos, Maria Izabel Campos Simplicio, Luciene Barra Ribeiro, Thalyne de Souza Medeiros, Thais Campos Siqueira, Taynara Silva Vieira, Nayara Drumond Rausse, Tereza Cristina Garofolo, Eliane Carreiro Fagundes Silva, Ofir Harari, Gennaro D'Urso, Jamie I Forrest, Jay Park, Jean P Nachega, Christopher Lindsell, Jeffrey S Glenn, Kristian Thorlund, Mark Dybul, Edward J Mills","doi":"10.7326/ANNALS-26-03050","DOIUrl":"https://doi.org/10.7326/ANNALS-26-03050","url":null,"abstract":"","PeriodicalId":7932,"journal":{"name":"Annals of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":17.2,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149103193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Annals Video Summary - Pharmacologic Treatments for Females With Menopausal Vasomotor Symptoms.","authors":"","doi":"10.7326/ANNALS-26-03182-VS","DOIUrl":"https://doi.org/10.7326/ANNALS-26-03182-VS","url":null,"abstract":"","PeriodicalId":7932,"journal":{"name":"Annals of Internal Medicine","volume":" ","pages":"e2603182VS"},"PeriodicalIF":17.2,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149103198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}