Annals of Internal Medicine最新文献_第2页

Cardiology: What You May Have Missed in 2024.

IF 19.6 1区医学

Annals of Internal Medicine Pub Date : 2025-04-01 DOI: 10.7326/ANNALS-25-00991

Shamal Khattak, Ahmed Al-Ansari, Maha Alfaraidhy, Fares Rajah, Michael Lacombe, William G Kussmaul

{"title":"Cardiology: What You May Have Missed in 2024.","authors":"Shamal Khattak, Ahmed Al-Ansari, Maha Alfaraidhy, Fares Rajah, Michael Lacombe, William G Kussmaul","doi":"10.7326/ANNALS-25-00991","DOIUrl":"https://doi.org/10.7326/ANNALS-25-00991","url":null,"abstract":"There have been many recent advancements in cardiology research, with numerous studies published across the multiple subspecialties. Having screened more than 1200 articles published in 2024, we summarize 10 studies in this article that highlight key changes in this field. Starting with atrial fibrillation (AF), we note articles that examine which patients benefit most from catheter ablation, a procedure that is becoming increasingly common. We then examine new evidence regarding anticoagulation in device-detected AF and in patients with AF and coronary disease. In patients with severe aortic stenosis, the timing of valve intervention in relation to development of symptoms was a hot topic and is addressed here. There have also been developments in treatment of heart failure with preserved ejection fraction, including research into medications such as finerenone and tirzepatide. Certain studies attempt to challenge our current medical practices, including routine use of β-blockers after myocardial infarction (MI) and holding of renin-angiotensin system inhibitors before noncardiac surgery. Finally, the role of invasive treatment strategies for older adults with non-ST-segment elevation MI has also been addressed.","PeriodicalId":7932,"journal":{"name":"Annals of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":19.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Endocrinology: What You May Have Missed in 2024.

IF 19.6 1区医学

Annals of Internal Medicine Pub Date : 2025-04-01 DOI: 10.7326/ANNALS-25-00990

Mohamed Aman, Athavi Jeevananthan, Maria Martinez-Cruz, Neesha Namasingh, Bryan C Batch

{"title":"Endocrinology: What You May Have Missed in 2024.","authors":"Mohamed Aman, Athavi Jeevananthan, Maria Martinez-Cruz, Neesha Namasingh, Bryan C Batch","doi":"10.7326/ANNALS-25-00990","DOIUrl":"https://doi.org/10.7326/ANNALS-25-00990","url":null,"abstract":"During 2024, there were many practice-changing innovations in the field of endocrinology, particularly related to the use of glucagon-like peptide-1 receptor agonists (GLP-1RAs). From the substantial new evidence published in 2024, 10 studies are highlighted that offer critical information for clinicians who manage or comanage patients with endocrine disorders including prediabetes, diabetes, obesity, and hyperparathyroidism. Two of the 10 articles are focused on use of GLP-1RAs in multiple clinical settings not studied in the original GLP-1RA trials, including after bariatric surgery and before endoscopy. Two additional studies focused on GLP-1RA explore the risk for thyroid cancer in patients prescribed GLP-1RA and the effect of a GLP-1RA on chronic kidney disease in patients with type 2 diabetes. Three articles investigate opportunities for deintensification of insulin frequency or an alternate method of insulin delivery in patients with type 2 diabetes. One article explores the cardiometabolic effects of intermittent fasting in persons with prediabetes and type 2 diabetes. The last 2 articles explore the incidence of diabetes after SARS-CoV-2 infection and the skeletal effects of parathyroidectomy as a treatment of hyperparathyroidism. The results of each study have a direct effect on the delivery of care for patients with prediabetes, type 2 diabetes, and hyperparathyroidism.","PeriodicalId":7932,"journal":{"name":"Annals of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":19.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unifying Efforts to Empower Equitable Obesity Care: Synopsis of an American College of Physicians and Council of Subspecialty Societies Summit.

IF 19.6 1区医学

Annals of Internal Medicine Pub Date : 2025-04-01 DOI: 10.7326/ANNALS-25-00675

Christina C Wee, Alicia I Arbaje, Harriet Bering, Linda Blount, Joshua J Joseph, Scott Kahan, Caroline M Apovian, Adrienne White-Faines

{"title":"Unifying Efforts to Empower Equitable Obesity Care: Synopsis of an American College of Physicians and Council of Subspecialty Societies Summit.","authors":"Christina C Wee, Alicia I Arbaje, Harriet Bering, Linda Blount, Joshua J Joseph, Scott Kahan, Caroline M Apovian, Adrienne White-Faines","doi":"10.7326/ANNALS-25-00675","DOIUrl":"https://doi.org/10.7326/ANNALS-25-00675","url":null,"abstract":"Obesity is a leading cause of morbidity and mortality with health consequences that crosscut most medical specialties. Despite the emergence of effective and promising new therapies, many impediments to comprehensive obesity care remain. As part of their commitment to improving obesity care, the American College of Physicians (ACP) and its Council of Subspecialty Societies (CSS) held a summit on 24 October 2023 to identify barriers to and opportunities for collaborative action in the domains of physician education, health care policy and care delivery, and addressing weight bias. This report summarizes the summit proceedings and provides a postsummit synthesis from ACP and CSS. Key themes were centered on knowledge, advocacy, action, and compassion, including the need for culture change, paradigm shifts, and stakeholder engagement and collaboration; a focus on empowerment of both clinicians and patients; the importance of knowing patients as people to help address social determinants of health; the need to address learned helplessness; and the importance of embracing artificial intelligence and technology as disruptive innovations. Recommendations for next steps for collaborative action include leveraging and improving already available educational and clinical resources, developing obesity education and care standards that incorporate patients' perspectives and address social determinants of health, developing community and public-private partnerships to improve access and public awareness, and coordinating messaging and policy advocacy efforts that align with mitigating the longstanding obesity epidemic.","PeriodicalId":7932,"journal":{"name":"Annals of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":19.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gastroenterology/Hepatology: What You May Have Missed in 2024.

IF 19.6 1区医学

Annals of Internal Medicine Pub Date : 2025-04-01 DOI: 10.7326/ANNALS-25-00959

Amber Cintosun, Imran Jamal, Sunil Samnani, Yi Nong Song, Michael Bretthauer

{"title":"Gastroenterology/Hepatology: What You May Have Missed in 2024.","authors":"Amber Cintosun, Imran Jamal, Sunil Samnani, Yi Nong Song, Michael Bretthauer","doi":"10.7326/ANNALS-25-00959","DOIUrl":"https://doi.org/10.7326/ANNALS-25-00959","url":null,"abstract":"This article highlights selected major advances in gastroenterology and hepatology from 2024 that are relevant for internal medicine specialists. In colorectal cancer (CRC) screening, new developments include a head-to-head comparison of different fecal immunochemical tests and a new blood-based DNA screening test, benefits and harms of artificial intelligence-assisted colonoscopy, and adenoma detection rate improvement and risk for cancer. Treatment options for metabolic dysfunction-associated steatotic liver disease now include resmetirom, a recently approved drug for treatment of patients with moderate-to-severe fibrosis, and liver transplantation may now be an option in patients with unresectable colorectal liver metastases. Also featured are new data on the efficacy of indomethacin and pancreatic stent placement for prevention of pancreatitis after endoscopic retrograde cholangiopancreatography and news on the efficacy and safety of zastaprazan, a new potassium-competitive acid blocker for reflux esophagitis. Finally, a recent randomized trial is highlighted that has dispelled concerns about potential harms of proton-pump inhibitors for stress ulcer prophylaxis in patients receiving invasive mechanical ventilation.","PeriodicalId":7932,"journal":{"name":"Annals of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":19.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Improving Health and Health Care in Rural Communities: A Position Paper From the American College of Physicians.

IF 19.6 1区医学

Annals of Internal Medicine Pub Date : 2025-04-01 DOI: 10.7326/ANNALS-24-03577

Josh Serchen, Dejaih Johnson, Katelan Cline, David Hilden, Leslie F Algase, Jenny R Silberger, Clyde Watkins

{"title":"Improving Health and Health Care in Rural Communities: A Position Paper From the American College of Physicians.","authors":"Josh Serchen, Dejaih Johnson, Katelan Cline, David Hilden, Leslie F Algase, Jenny R Silberger, Clyde Watkins","doi":"10.7326/ANNALS-24-03577","DOIUrl":"https://doi.org/10.7326/ANNALS-24-03577","url":null,"abstract":"Rural communities throughout the United States experience disparities in health and access to health care. Low population densities, isolating terrain, and vast geographic distances to other population centers create barriers to attracting and retaining physicians and other health professionals. The characteristics of rural communities also pose barriers to facilitating robust economic activity conducive to the production of health and the presence of health care facilities. As such, rural communities have faced high levels of hospital closures and \"diseases of despair,\" such as opioid misuse and suicide. The heterogeneity of rural geographies and population characteristics produces unique and differing challenges across communities that require tailored policy interventions. Interventions that are culturally appropriate for rural communities must be adopted that address diseases and health conditions that impact rural populations and the related social and economic conditions that create and perpetuate these diseases and health conditions. Policymakers must invest in the economies, social services, and infrastructure of rural communities, especially those programs that provide health coverage and services to them. Ensuring access to telehealth is a critical component of expanding health care access. Medical education institutions and the medical community at large have a responsibility to equip physicians and physicians-in-training to care for rural communities and provide opportunities for trainees to practice in rural settings. These institutions must be supported through public policy that incentivizes the recruitment and retainment of a qualified physician workforce in rural communities.","PeriodicalId":7932,"journal":{"name":"Annals of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":19.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In adults with trauma, an early restrictive vs. liberal oxygen strategy did not reduce death or major respiratory complications at 30 d.

IF 19.6 1区医学

Annals of Internal Medicine Pub Date : 2025-04-01 DOI: 10.7326/ANNALS-25-00805-JC

Joshua Detelich, Greg S Martin

引用次数: 0

Oncology: What You May Have Missed in 2024.

IF 19.6 1区医学

Annals of Internal Medicine Pub Date : 2025-04-01 DOI: 10.7326/ANNALS-25-00963

Zainab Ali Amer Al Maqrashi, Sze Wah Samuel Chan, Zeba Siddiqui, Efrat Dotan

{"title":"Oncology: What You May Have Missed in 2024.","authors":"Zainab Ali Amer Al Maqrashi, Sze Wah Samuel Chan, Zeba Siddiqui, Efrat Dotan","doi":"10.7326/ANNALS-25-00963","DOIUrl":"https://doi.org/10.7326/ANNALS-25-00963","url":null,"abstract":"Over the past 5 decades, substantial advances in oncology have reshaped cancer care, reflecting the dynamic role of internal medicine physicians in patients' journey from screening to diagnosis, treatment, and surveillance. This review highlights 10 landmark studies from 2024 that address emerging therapies and evolving clinical standards. Immunotherapy remains a central focus, with checkpoint inhibitors redefining the management of solid tumors and showing expanded applications across disease sites and earlier stages of disease. Targeted therapies and antibody-drug conjugates, including trastuzumab deruxtecan and enfortumab vedotin, are enhancing precision treatment options in metastatic cancer. Meanwhile, advances in supportive care, such as magnetic resonance imaging-guided prostate cancer screening, ponsegromab for cachexia, and celiac plexus radiosurgery for pain, show enhanced symptom management and quality of life for patients. These innovations highlight the critical role of multidisciplinary approaches, where internal medicine physicians contribute to co-management and toxicity monitoring, ultimately optimizing patient care. By staying current with these developments, internal medicine physicians are positioned to navigate complex oncologic care, ensuring that the benefits of novel therapies are maximized while mitigating their challenges.","PeriodicalId":7932,"journal":{"name":"Annals of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":19.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction: Visual Guideline - Pharmacologic Treatments of Acute Episodic Migraine Headache in Outpatient Settings.

IF 19.6 1区医学

Annals of Internal Medicine Pub Date : 2025-04-01 DOI: 10.7326/ANNALS-25-01492

引用次数: 0

In older adults with severe AS and complex CAD, PCI + TAVI vs. SAVR + CABG reduced patient-oriented outcomes at 1 y.

IF 19.6 1区医学

Annals of Internal Medicine Pub Date : 2025-04-01 DOI: 10.7326/ANNALS-25-00804-JC

Paolo Ciacci, Giulio Francesco Romiti, Bernadette Corica

引用次数: 0

Rheumatology: What You May Have Missed in 2024.

IF 19.6 1区医学

Annals of Internal Medicine Pub Date : 2025-04-01 DOI: 10.7326/ANNALS-25-00927

Brandon J Blau, Lisa A Mandl

{"title":"Rheumatology: What You May Have Missed in 2024.","authors":"Brandon J Blau, Lisa A Mandl","doi":"10.7326/ANNALS-25-00927","DOIUrl":"https://doi.org/10.7326/ANNALS-25-00927","url":null,"abstract":"Internal medicine physicians are frequently responsible for caring for patients with rheumatologic diseases, whether as a primary provider or in collaboration with subspecialists. This article calls attention to 8 studies published in 2024 that shed new light on the management of common rheumatologic conditions that internal medicine physicians are likely to encounter. The first study suggests that the weight loss medication semaglutide can improve pain and function in patients with painful knee osteoarthritis (OA), potentially providing a novel approach to management of this condition. The results of the second study show that methotrexate, a proven therapy for inflammatory arthritis, has promise for improving pain in patients with knee OA. The third study establishes that a trial of resistance training does not provide similar benefits as total joint replacement for patients with hip OA. The fourth study finds that platelet-rich plasma injections are no more effective than exercise in reducing pain for patients with knee OA. The fifth study underscores the importance of screening for lung cancer in patients with rheumatoid arthritis (RA), particularly in those known to have interstitial lung disease. The results of the sixth study emphasize that exercise therapy is safe and effective at improving function in patients with RA and severe activity limitations. The seventh study highlights the increased short-term risk for acute cardiovascular events in patients experiencing a new gout diagnosis. The final study suggests that supplementation with omega-3 fatty acids may provide sustained protection against developing new autoimmune diseases. Familiarity with these new studies will provide internal medicine physicians with valuable insights to enhance their care of patients with rheumatic diseases.","PeriodicalId":7932,"journal":{"name":"Annals of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":19.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0