Annals of Internal Medicine最新文献

{"title":"Staging Obesity Risk Beyond Body Mass Index: Progress Made but More to Do.","authors":"Christina C Wee, Bryan C Batch, Eliseo Guallar","doi":"10.7326/ANNALS-25-02327","DOIUrl":"https://doi.org/10.7326/ANNALS-25-02327","url":null,"abstract":"","PeriodicalId":7932,"journal":{"name":"Annals of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":19.6,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144582867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Annals Graphic Medicine - First (Future) Doctor in the Family.","authors":"Ariana Chen","doi":"10.7326/ANNALS-24-01548-GM","DOIUrl":"https://doi.org/10.7326/ANNALS-24-01548-GM","url":null,"abstract":"","PeriodicalId":7932,"journal":{"name":"Annals of Internal Medicine","volume":" ","pages":"e2401548GM"},"PeriodicalIF":19.6,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144582853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Summary for Patients: Development and Validation of Body Mass Index-Specific Waist Circumference Thresholds in Postmenopausal Women.","authors":"","doi":"10.7326/ANNALS-24-00713-PS","DOIUrl":"https://doi.org/10.7326/ANNALS-24-00713-PS","url":null,"abstract":"","PeriodicalId":7932,"journal":{"name":"Annals of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":19.6,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144582868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Licensing Internationally Trained Physicians: Advisory Commission Leaders Share Initial Progress.","authors":"Humayun J Chaudhry, John R Combes, Eric S Holmboe, Katie L Templeton, George M Abraham","doi":"10.7326/ANNALS-25-00936","DOIUrl":"https://doi.org/10.7326/ANNALS-25-00936","url":null,"abstract":"","PeriodicalId":7932,"journal":{"name":"Annals of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":19.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144526165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reducing the Over-Diagnosis of Thyroid Disease.","authors":"James V Hennessey","doi":"10.7326/ANNALS-25-01333","DOIUrl":"10.7326/ANNALS-25-01333","url":null,"abstract":"","PeriodicalId":7932,"journal":{"name":"Annals of Internal Medicine","volume":" ","pages":"1040-1041"},"PeriodicalIF":19.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143964097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Summary for Patients: Moderate- to Long-Term Effect of Dietary Interventions for Depression and Anxiety.","authors":"","doi":"10.7326/ANNALS-24-03016-PS","DOIUrl":"10.7326/ANNALS-24-03016-PS","url":null,"abstract":"","PeriodicalId":7932,"journal":{"name":"Annals of Internal Medicine","volume":" ","pages":"I14"},"PeriodicalIF":19.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144101330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of a Hypotension-Avoidance Versus a Hypertension-Avoidance Strategy on Neurocognitive Outcomes After Noncardiac Surgery.","authors":"Maura Marcucci, Matthew T V Chan, Thomas W Painter, Sergey Efremov, Hector J Aguado, Sergey V Astrakov, Ydo V Kleinlugtenbelt, Ameen Patel, Juan P Cata, Mohammed Amir, Mikhail Kirov, Kate Leslie, Emmanuelle Duceppe, Flavia K Borges, Miriam de Nadal, Vikas Tandon, Giovanni Landoni, Valery V Likhvantsev, Vladimir Lomivorotov, Daniel I Sessler, María José Martínez-Zapata, Denis Xavier, Edith Fleischmann, Chew Yin Wang, Christian S Meyhoff, Maria Wittmann, David Torres, David Highton, Michael Jacka, Vishwanath B, Kelly Zarnke, Ravinder Singh Sidhu, Giorgio Oriani, Sabry Ayad, Steven Minear, Tristan E Weaver, Kurt Ruetzler, Claudia Brusasco, Joel L Parlow, Elizabeth Maxwell, Scott Miller, Marko Mrkobrada, Keyur Suresh Chandra Bhatt, Prashant Rahate, Ana Kowark, Giuseppe De Blasio, Sandra N Ofori, David Conen, Sadeesh Srinathan, Wojciech Szczeklik, Raja Jayaram, Richard K Ellerkmann, Mona Momeni, Ingrid Copland, Jessica Vincent, Kumar Balasubramanian, Zhuoru Li, Michael Ke Wang, Deyang Li, Michael H McGillion, Andrea Kurz, Mukul Sharma, Timothy G Short, P J Devereaux","doi":"10.7326/ANNALS-24-02841","DOIUrl":"10.7326/ANNALS-24-02841","url":null,"abstract":"<p><strong>Background: </strong>Perioperative hemodynamic abnormalities have been associated with neurocognitive outcomes after noncardiac surgery.</p><p><strong>Objective: </strong>To compare the effects of perioperative hypotension-avoidance versus hypertension-avoidance strategies on delirium and 1-year cognitive decline after noncardiac surgery.</p><p><strong>Design: </strong>Randomized controlled trial. (ClinicalTrials.gov: NCT03505723).</p><p><strong>Setting: </strong>54 centers, 19 countries.</p><p><strong>Participants: </strong>2603 high-vascular-risk patients undergoing noncardiac surgery, receiving 1 or more chronic antihypertensive medications (mean age, 70 years).</p><p><strong>Intervention: </strong>In the hypotension-avoidance strategy, the intraoperative mean arterial pressure (MAP) target was 80 mm Hg or greater; before and for 2 days after surgery, renin-angiotensin-aldosterone system inhibitors were withheld, and other chronic antihypertensive medications were administered for systolic blood pressures of 130 mm Hg or greater following an algorithm. In the hypertension-avoidance strategy, the intraoperative MAP target was 60 mm Hg or greater; all chronic antihypertensive medications were continued perioperatively.</p><p><strong>Measurements: </strong>Delirium on postoperative day 1 to 3 (primary outcome); decline of 2 points or more at the Montreal Cognitive Assessment (MoCA) 1 year after surgery compared with baseline (secondary outcome).</p><p><strong>Results: </strong>95 of 1310 patients (7.3%) in the hypotension-avoidance and 90 of 1293 patients (7.0%) in the hypertension-avoidance group had delirium (relative risk [RR], 1.04 [95% CI, 0.79 to 1.38]). Among 701 patients who completed 1-year MoCA (full or telephone version), 129 of 347 (37.2%) in the hypotension-avoidance and 117 of 354 (33.1%) in the hypertension-avoidance group had a decline of 2 or more points (RR, 1.13 [CI, 0.92 to 1.38]). Nineteen percent in the hypotension-avoidance and 27% in the hypertension-avoidance strategy had hypotension requiring an intervention (RR, 0.63 [CI, 0.52 to 0.76]), mostly intraoperatively; only 5%, in both groups, had hypotension postoperatively.</p><p><strong>Limitation: </strong>The COVID-19 pandemic challenged site participation in the substudy; although large, the sample size was lower than expected.</p><p><strong>Conclusion: </strong>There was no evidence of a difference in neurocognitive outcomes between the hypotension-avoidance and hypertension-avoidance strategies.</p><p><strong>Primary funding source: </strong>Canadian Institutes of Health Research, Canada; National Health and Medical Research Council, Australia; Research Grant Council, Hong Kong SAR, China.</p>","PeriodicalId":7932,"journal":{"name":"Annals of Internal Medicine","volume":" ","pages":"909-920"},"PeriodicalIF":19.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144207446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Precision Social Care Delivery.","authors":"Sahil Sandhu, Michael Liu, Laura M Gottlieb, Rishi Manchanda","doi":"10.7326/ANNALS-25-00323","DOIUrl":"10.7326/ANNALS-25-00323","url":null,"abstract":"","PeriodicalId":7932,"journal":{"name":"Annals of Internal Medicine","volume":" ","pages":"1035-1037"},"PeriodicalIF":19.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144257165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Web Exclusive. Annals Consult Guys - Should Antihypertensive Therapy Be Optimized Before Hospital Discharge?","authors":"Howard H Weitz, Geno J Merli, Timothy Anderson","doi":"10.7326/ANNALS-25-03067-CG","DOIUrl":"https://doi.org/10.7326/ANNALS-25-03067-CG","url":null,"abstract":"","PeriodicalId":7932,"journal":{"name":"Annals of Internal Medicine","volume":"178 7","pages":"e2503067CG"},"PeriodicalIF":19.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144635955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Web Exclusive. Annals Guide to Journal Club - Cumulative Incidence of Thiazide-Induced Hyponatremia.","authors":"Desiree Burroughs-Ray, Maniraj Neupane, Christina C Wee","doi":"10.7326/ANNALS-25-02549-AG","DOIUrl":"https://doi.org/10.7326/ANNALS-25-02549-AG","url":null,"abstract":"","PeriodicalId":7932,"journal":{"name":"Annals of Internal Medicine","volume":"178 7","pages":"e2502549AG"},"PeriodicalIF":19.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144635958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}