Annals of Internal Medicine最新文献

{"title":"Correction: Anticoagulation Among Patients Hospitalized for COVID-19.","authors":"","doi":"10.7326/ANNALS-25-00916","DOIUrl":"10.7326/ANNALS-25-00916","url":null,"abstract":"","PeriodicalId":7932,"journal":{"name":"Annals of Internal Medicine","volume":" ","pages":"608"},"PeriodicalIF":19.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143647093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rheumatology: What You May Have Missed in 2024.","authors":"Brandon J Blau, Lisa A Mandl","doi":"10.7326/ANNALS-25-00927","DOIUrl":"https://doi.org/10.7326/ANNALS-25-00927","url":null,"abstract":"<p><p>Internal medicine physicians are frequently responsible for caring for patients with rheumatologic diseases, whether as a primary provider or in collaboration with subspecialists. This article calls attention to 8 studies published in 2024 that shed new light on the management of common rheumatologic conditions that internal medicine physicians are likely to encounter. The first study suggests that the weight loss medication semaglutide can improve pain and function in patients with painful knee osteoarthritis (OA), potentially providing a novel approach to management of this condition. The results of the second study show that methotrexate, a proven therapy for inflammatory arthritis, has promise for improving pain in patients with knee OA. The third study establishes that a trial of resistance training does not provide similar benefits as total joint replacement for patients with hip OA. The fourth study finds that platelet-rich plasma injections are no more effective than exercise in reducing pain for patients with knee OA. The fifth study underscores the importance of screening for lung cancer in patients with rheumatoid arthritis (RA), particularly in those known to have interstitial lung disease. The results of the sixth study emphasize that exercise therapy is safe and effective at improving function in patients with RA and severe activity limitations. The seventh study highlights the increased short-term risk for acute cardiovascular events in patients experiencing a new gout diagnosis. The final study suggests that supplementation with omega-3 fatty acids may provide sustained protection against developing new autoimmune diseases. Familiarity with these new studies will provide internal medicine physicians with valuable insights to enhance their care of patients with rheumatic diseases.</p>","PeriodicalId":7932,"journal":{"name":"Annals of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":19.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient Navigation to Improve Colonoscopy Completion After an Abnormal Stool Test Result : A Randomized Controlled Trial.","authors":"Gloria D Coronado, Amanda F Petrik, Jamie H Thompson, Michael C Leo, Matthew Slaughter, Priyanka Gautom, Syed A Hussain, Leslie Mosso, Jeffrey Gibbs, Neha Yadav, Rajasekhara R Mummadi, Eric S Johnson, Ricardo Jimenez","doi":"10.7326/ANNALS-24-01885","DOIUrl":"https://doi.org/10.7326/ANNALS-24-01885","url":null,"abstract":"<p><strong>Background: </strong>Patient navigation is a recommended practice of the Guide to Community Preventive Services; little is known about whether it improves colonoscopy completion for adults who have received an abnormal stool test result.</p><p><strong>Objective: </strong>To determine whether patient navigation delivered to persons with an abnormal stool test result increased follow-up colonoscopy completion (primary) at 1 year.</p><p><strong>Design: </strong>Randomized controlled trial. (ClinicalTrials.gov: NCT03925883).</p><p><strong>Setting: </strong>A federally qualified health center (<i>n</i> = 32 clinics) in Washington state.</p><p><strong>Patients: </strong>Persons aged 50 to 75 years with an abnormal fecal test result in the prior month.</p><p><strong>Intervention: </strong>A 6-topic, telephone-based patient navigation program delivered by bilingual (English and Spanish) clinical staff.</p><p><strong>Measurements: </strong>Receipt of follow-up colonoscopy at 1 year (primary); time to colonoscopy receipt (secondary); and program effectiveness by patient characteristics, including patients' probability of obtaining a colonoscopy without navigation, derived using health record data (secondary).</p><p><strong>Results: </strong>Of 985 participants enrolled (mean age, 61 years [SD, 6.8]; 170 [18%] had a Spanish-language preference listed in the medical record), 967 were included in the primary intention-to-treat analysis (479 in patient navigation, 488 in usual care). Receipt of follow-up colonoscopy was higher in the patient navigation group than in the usual care group (55.1% vs. 42.1%; risk difference, 13.0 percentage points [95% CI, 6.5 to 19.4 percentage points]). The intervention effect was not moderated by patients' probability of obtaining a colonoscopy without navigation.</p><p><strong>Limitation: </strong>The study was primarily done during the height of the COVID-19 pandemic, which created additional barriers to colonoscopy at the health system and patient levels.</p><p><strong>Conclusion: </strong>These findings support the effectiveness of patient navigation for follow-up colonoscopy completion.</p><p><strong>Primary funding source: </strong>National Cancer Institute.</p>","PeriodicalId":7932,"journal":{"name":"Annals of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":19.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Annals Graphic Medicine - Hive Mind: The Student Experience.","authors":"Dinukie-Chantal W Perera","doi":"10.7326/ANNALS-24-01078-GM","DOIUrl":"10.7326/ANNALS-24-01078-GM","url":null,"abstract":"","PeriodicalId":7932,"journal":{"name":"Annals of Internal Medicine","volume":" ","pages":"e2401078GM"},"PeriodicalIF":19.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143802287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coadministration of RSV + influenza or COVID-19 vaccines was noninferior to separate administration for immune responses in adults aged ≥50 y.","authors":"Clifford C Dacso","doi":"10.7326/ANNALS-25-00904-JC","DOIUrl":"10.7326/ANNALS-25-00904-JC","url":null,"abstract":"<p><strong>Clinical impact ratings: </strong>GIM/FP/GP: [Formula: see text] Infectious Disease: [Formula: see text] Pulmonology: [Formula: see text] Public Health: [Formula: see text].</p>","PeriodicalId":7932,"journal":{"name":"Annals of Internal Medicine","volume":" ","pages":"JC41"},"PeriodicalIF":19.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In adults treated with OACs after a first VTE, NSAID use was linked to increased risk for bleeding.","authors":"Geoffrey D Barnes","doi":"10.7326/ANNALS-25-00368-JC","DOIUrl":"10.7326/ANNALS-25-00368-JC","url":null,"abstract":"<p><strong>Clinical impact ratings: </strong>GIM/FP/GP: [Formula: see text] Hematology: [Formula: see text].</p>","PeriodicalId":7932,"journal":{"name":"Annals of Internal Medicine","volume":" ","pages":"JC47"},"PeriodicalIF":19.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In menopause-related moderate-to-severe vasomotor symptoms not suitable for hormone therapy, fezolinetant safely improved symptoms.","authors":"Angela M Cheung","doi":"10.7326/ANNALS-25-00829-JC","DOIUrl":"10.7326/ANNALS-25-00829-JC","url":null,"abstract":"<p><strong>Clinical impact ratings: </strong>GIM/FP/GP: [Formula: see text].</p>","PeriodicalId":7932,"journal":{"name":"Annals of Internal Medicine","volume":" ","pages":"JC46"},"PeriodicalIF":19.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial Intelligence in Medical Practice: Is It Ready?","authors":"Jerome P Kassirer","doi":"10.7326/ANNALS-25-00472","DOIUrl":"10.7326/ANNALS-25-00472","url":null,"abstract":"","PeriodicalId":7932,"journal":{"name":"Annals of Internal Medicine","volume":" ","pages":"596-597"},"PeriodicalIF":19.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143778717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute Pain Management in People With Opioid Use Disorder : A Systematic Review.","authors":"Michele J Buonora, Katherine Mackey, Laila Khalid, Thomas R Hickey, Alyssa A Grimshaw, Max Moss, Joanna L Starrels, Daniel P Alford, William C Becker, Melissa B Weimer","doi":"10.7326/ANNALS-24-01917","DOIUrl":"10.7326/ANNALS-24-01917","url":null,"abstract":"<p><strong>Background: </strong>Guidance on acute pain management among people with opioid use disorder (OUD) is limited.</p><p><strong>Purpose: </strong>To synthesize evidence on the benefits and harms of acute pain interventions among people with OUD.</p><p><strong>Data sources: </strong>APA PsycArticles, APA PsycInfo, APA PsycExtra, Allied and Complementary Medicine Database, CINAHL, Cochrane Library, Google Scholar, Ovid Embase, Ovid MEDLINE, PubMed, Scopus, and the Web of Science Core Collection through 7 July 2024.</p><p><strong>Study selection: </strong>Studies of any design that evaluated acute pain interventions among adults with OUD and included pain or OUD outcomes.</p><p><strong>Data extraction: </strong>Independent dual screening, single-investigator data extraction with verification, and dual quality and strength of evidence assessment.</p><p><strong>Data synthesis: </strong>Seventeen trials, 20 controlled observational studies, and 78 uncontrolled observational studies met eligibility criteria. Continuing use of buprenorphine during acute pain episodes may be associated with similar or improved pain-related outcomes versus discontinuing, based on cohort studies conducted primarily in perioperative settings. Single well-conducted randomized controlled trials in emergency department (ED) or perioperative settings in adults not prescribed medications for OUD suggest oral clonidine, intramuscular haloperidol and midazolam with intravenous (IV) morphine, and intraoperative IV lidocaine may improve pain outcomes and warrant study in diverse patient populations. Few studies evaluated methadone or the effect of interventions on OUD outcomes.</p><p><strong>Limitations: </strong>Most evidence is observational and at risk of bias due to confounding. All studies were conducted in ED or hospital settings, most before widespread use of high-potency synthetic opioids or among non-U.S. populations using opium.</p><p><strong>Conclusion: </strong>The overall evidence for pain outcomes in people with OUD is low. The effect of pain interventions on OUD outcomes is an important evidence gap.</p><p><strong>Primary funding source: </strong>None. (Protocol registered a priori on Open Science Framework [https://osf.io/25hbs]).</p>","PeriodicalId":7932,"journal":{"name":"Annals of Internal Medicine","volume":" ","pages":"558-570"},"PeriodicalIF":19.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143647038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"There Is No Substitute for Primary Care Physicians: A Response to the Association of American Medical Colleges' Workforce Model.","authors":"Christin Giordano McAuliffe","doi":"10.7326/ANNALS-24-03806","DOIUrl":"10.7326/ANNALS-24-03806","url":null,"abstract":"","PeriodicalId":7932,"journal":{"name":"Annals of Internal Medicine","volume":" ","pages":"590-591"},"PeriodicalIF":19.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143603475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}