The European Physical Journal Plus最新文献

筛选
英文 中文
Curvature-driven acceleration and a notion of vacuum in Nash theory 曲率驱动的加速度和纳什理论中的真空概念
IF 2.8 3区 物理与天体物理
The European Physical Journal Plus Pub Date : 2025-04-24 DOI: 10.1140/epjp/s13360-025-06258-4
Soumya Chakrabarti, Soumya Bhattacharya, Rabin Banerjee, Amitabha Lahiri
{"title":"Curvature-driven acceleration and a notion of vacuum in Nash theory","authors":"Soumya Chakrabarti,&nbsp;Soumya Bhattacharya,&nbsp;Rabin Banerjee,&nbsp;Amitabha Lahiri","doi":"10.1140/epjp/s13360-025-06258-4","DOIUrl":"10.1140/epjp/s13360-025-06258-4","url":null,"abstract":"<div><p>We discuss the cosmological implications in the <i>Nash theory</i> of gravity, where the field equations are derived from a lagrangian quadratic in Ricci invariants. A spatially homogeneous exact solution is found which can serve as a cosmological toy model. The implications of this model (departures from a standard <span>(Lambda)</span>CDM cosmology) are compared with standard observational expectations, using a Markov chain Monte Carlo simulation of <span>(JLA + OHD + BAO)</span> datasets. The Hubble evolution is satisfactory compared to the luminosity distance modulus measurements, and the evolution of deceleration parameter suggests an epoch of deceleration prior to the present acceleration. The redshift of transition is found to be quite satisfactory.</p></div>","PeriodicalId":792,"journal":{"name":"The European Physical Journal Plus","volume":"140 4","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143865519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Microbeam irradiation reveals cytoplasmic damage contributes to micronuclei induction 微束辐照显示细胞质损伤有助于微核诱导
IF 2.8 3区 物理与天体物理
The European Physical Journal Plus Pub Date : 2025-04-23 DOI: 10.1140/epjp/s13360-025-06265-5
Teruaki Konishi, Jun Wang, Alisa Kobayashi, Cuihua Liu, Yota Hiroyama, Taisei Mamiya, Tamon Kusumoto, Masakazu Oikawa
{"title":"Microbeam irradiation reveals cytoplasmic damage contributes to micronuclei induction","authors":"Teruaki Konishi,&nbsp;Jun Wang,&nbsp;Alisa Kobayashi,&nbsp;Cuihua Liu,&nbsp;Yota Hiroyama,&nbsp;Taisei Mamiya,&nbsp;Tamon Kusumoto,&nbsp;Masakazu Oikawa","doi":"10.1140/epjp/s13360-025-06265-5","DOIUrl":"10.1140/epjp/s13360-025-06265-5","url":null,"abstract":"<div><p>Microbeam technology offers a valuable tool for investigating inter- and intracellular responses to radiation-induced damage. This study investigated the contribution of cytoplasmic irradiation to micronuclei (MN) induction using proton microbeams. Three irradiation conditions were employed: (N) nucleus-only, (C) cytoplasm-only, and (N + C) irradiating both. In N + C, 1000 protons were delivered to the cytoplasm. For both N and N + C, MN induction increased proportionally with nuclear proton dose (Np) within the 0 ≤ Np ≤ 100 range. However, the N + C slope was 2/3 of the N slope. N cells exhibited peak MN induction at 150 protons, while N + C peaked at 300 protons. Cytoplasmic irradiation alone also induced MNs, but with a lower slope and reaching a plateau after Np = 300. These results demonstrate that cytoplasmic damage not only contributes to MN induction but also appears to promote protective cellular responses. This highlights the complex interplay between cellular organelles during radiation exposure and emphasizes the importance of considering cytoplasmic contributions to cellular radioresistance.</p></div>","PeriodicalId":792,"journal":{"name":"The European Physical Journal Plus","volume":"140 4","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143865501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Data-driven discovery of phase field dynamics: a physics-informed neural network-based approach to the Allen–Cahn equation 数据驱动的相场动力学发现:Allen-Cahn方程的基于物理信息的神经网络方法
IF 2.8 3区 物理与天体物理
The European Physical Journal Plus Pub Date : 2025-04-23 DOI: 10.1140/epjp/s13360-025-06267-3
Nek Muhammad Katbar, Shengjun Liu, Hongjuan Liu
{"title":"Data-driven discovery of phase field dynamics: a physics-informed neural network-based approach to the Allen–Cahn equation","authors":"Nek Muhammad Katbar,&nbsp;Shengjun Liu,&nbsp;Hongjuan Liu","doi":"10.1140/epjp/s13360-025-06267-3","DOIUrl":"10.1140/epjp/s13360-025-06267-3","url":null,"abstract":"<div><p>This paper aims to analyze the adoption of physics-informed neural networks (PINNs) in solving the Allen–Cahn equation, which represents a fundamental model in phase field dynamics that captures processes such as phase segregation and interface dynamics in materials. To solve the Allen–Cahn equating system under three different initial conditions, PINNs have been employed and shown to achieve very reflective solutions with few numbers of iterations. A comparison with standard numerical solutions verifies the good accuracy of PINN in modeling the nonlinear dynamics of complicated systems. The results indicate that initial conditions play an important role in the rate and nature of phase evolution: lower amplitude initial perturbations reach equilibrium configurations more quickly with minimum interface roughness, whereas higher initial amplitudes represent multi-stage complex interface evolution. It is evident that the dynamics of the Allen–Cahn equation force the phase field toward equilibrium by minimizing the interfacial energy in time. This study further examines the influence of the mobility (<i>L</i>) and interface (<i>ϵ</i>) thickness on phase evolution. Higher mobility accelerates interface migration, thereby enhancing phase separation, although rapidly changing initial conditions present an exception, temporarily increasing interfacial complexity. Similarly, the impact of the interface thickness varies with the initial profile, offering uniform phase separation for smoother configurations, but exhibiting spatially uneven effects when the initial profile contains abrupt variations. These findings highlight PINNs as a highly effective tool for phase field modeling, capable of simulating dynamic systems with accuracy and computational efficiency, thus extending the scope of PINNs in kinetic-controlled applications such as alloy solidification and polymer phase separation.</p></div>","PeriodicalId":792,"journal":{"name":"The European Physical Journal Plus","volume":"140 4","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143861303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Heat exchange improvement and drag force reduction around a heated square cylinder controlled by three partitions 由三个隔板控制的加热方形圆柱周围的热交换改善和阻力减少
IF 2.8 3区 物理与天体物理
The European Physical Journal Plus Pub Date : 2025-04-23 DOI: 10.1140/epjp/s13360-025-06270-8
Youssef Admi, Mohammed Amine Moussaoui, Ahmed Mezrhab
{"title":"Heat exchange improvement and drag force reduction around a heated square cylinder controlled by three partitions","authors":"Youssef Admi,&nbsp;Mohammed Amine Moussaoui,&nbsp;Ahmed Mezrhab","doi":"10.1140/epjp/s13360-025-06270-8","DOIUrl":"10.1140/epjp/s13360-025-06270-8","url":null,"abstract":"<div><p>This paper presents a detailed numerical study of airflow and heat transfer around a heated square obstacle controlled by three partitions in a horizontal channel at a fixed Reynolds number (<span>(text{Re} = 150)</span>). The numerical approach employed is the lattice Boltzmann method (LBM). The primary objective is to examine the influence of key geometric parameters, namely the gap spacing <i>g</i> between the cylinder and the partitions, and the partition’s length <span>(Lp)</span>, on both drag reduction and heat exchange enhancement. The results highlight that when the partitions are positioned upstream of the obstacle, a significant reduction in the drag coefficient is achieved due to the disruption of the approaching boundary layer, which weakens the vortex shedding behind the cylinder. The peak drag reduction of <span>(66.10%)</span> is observed at <span>(g=1.5d)</span>, as the partitions effectively mitigate the adverse pressure gradient in the wake region. Further increasing the partition length to <span>(Lp=2.5d)</span> enhances this effect, leading to a maximum drag reduction of <span>(72.68%)</span>. This configuration also promotes better thermal mixing, resulting in a uniform and consistent heat transfer enhancement across the obstacle’s surfaces. In contrast, when the partitions are placed downstream of the obstacle, the reduction in drag is less pronounced, reaching a maximum of <span>(31.45%)</span> at <span>(g=2.5d)</span>. This is because the vortex shedding remains active, albeit with reduced intensity. However, this setup significantly enhances convective heat transfer, increasing the Nusselt number by <span>(14%)</span> compared to the case without partitions. The downstream partitions serve as flow stabilizers, promoting heat advection away from the heated surfaces and reducing thermal recirculation zones. The most efficient configuration combines both upstream and downstream partitions, leading to an optimal aerodynamic and thermal performance. In this case, the upstream partitions effectively weaken the vortex shedding, while the downstream partitions act as additional flow stabilizers, further reducing pressure drag. This synergistic effect results in a maximal drag reduction of <span>(78.31%)</span>, coupled with a <span>(15.35%)</span> improvement in the Nusselt number. The presence of both partitions ensures a more uniform temperature distribution and enhances convective heat dissipation, demonstrating the effectiveness of flow control strategies in optimizing both aerodynamic and thermal characteristics.</p></div>","PeriodicalId":792,"journal":{"name":"The European Physical Journal Plus","volume":"140 4","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143861306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Global stability and Hopf bifurcation of a delayed HIV model with macrophages, CD4+T cells with latent reservoirs and immune response 巨噬细胞、CD4+T细胞潜伏库和免疫应答的迟发性HIV模型的全局稳定性和Hopf分叉
IF 2.8 3区 物理与天体物理
The European Physical Journal Plus Pub Date : 2025-04-23 DOI: 10.1140/epjp/s13360-025-06001-z
Hanane Hmarrass, Redouane Qesmi
{"title":"Global stability and Hopf bifurcation of a delayed HIV model with macrophages, CD4+T cells with latent reservoirs and immune response","authors":"Hanane Hmarrass,&nbsp;Redouane Qesmi","doi":"10.1140/epjp/s13360-025-06001-z","DOIUrl":"10.1140/epjp/s13360-025-06001-z","url":null,"abstract":"<div><p>In the present paper, we have proposed and analyzed a delayed HIV model with macrophages, CD4+T cells with latent reservoirs and immune response. We proved that our model leads to the existence of four infected equilibria together with the disease-free equilibrium. It is demonstrated that under some conditions the equilibria are globally asymptotically stable. Moreover, by considering the delay as the bifurcation parameter, the delayed model undergoes a Hopf bifurcation at some critical values of the delay. Numerical simulations approving the theoretical results are also included. Furthermore, we explored the effect of locking the latent reservoir on model behavior under the presence of CTL immune response. The model shows that pharmacological inhibitors such as molecule inhibitors of the lysine-specific demethylase 1 (LSD1/KDM1) regimens have no significant effect on viral clearance despite the presence of very high CTL responsiveness of macrophages immune-stimulated. However, such treatments can achieve very low levels of HIV when CTL activation against CD4+T infected cells is very high. This explains the limitation of the CTL response to eliminate the virus after locking the latent reservoir. These findings constitute an important step toward control strategies to reduce HIV infection and understanding HIV dynamics.</p></div>","PeriodicalId":792,"journal":{"name":"The European Physical Journal Plus","volume":"140 4","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143865500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impacts of refuge and additional foods on the spatiotemporal dynamics of a prey-predator system in a time-periodic environment 避难所和额外食物对时间周期环境中猎物-食肉动物系统时空动态的影响
IF 2.8 3区 物理与天体物理
The European Physical Journal Plus Pub Date : 2025-04-22 DOI: 10.1140/epjp/s13360-025-06253-9
Yi Wang, Qing Guo, He Liu, Subarna Roy, Pankaj Kumar Tiwari, Min Zhao, Chuanjun Dai
{"title":"Impacts of refuge and additional foods on the spatiotemporal dynamics of a prey-predator system in a time-periodic environment","authors":"Yi Wang,&nbsp;Qing Guo,&nbsp;He Liu,&nbsp;Subarna Roy,&nbsp;Pankaj Kumar Tiwari,&nbsp;Min Zhao,&nbsp;Chuanjun Dai","doi":"10.1140/epjp/s13360-025-06253-9","DOIUrl":"10.1140/epjp/s13360-025-06253-9","url":null,"abstract":"<div><p>In this investigation, we study the dynamics of a diffusive prey-predator system in a time-periodic environment, incorporating prey refuge and supplementary food resources for predators. We establish solution’s boundedness, and derive the conditions for population persistence and extinction. We find that whenever both prey and predator populations persist, a unique periodic solution arises that is globally asymptotically stable. Our numerical results show that increasing prey refuge (or alternative food) stabilizes the system, shifting it from oscillatory behavior to stable coexistence. However, excessive alternative food availability can drive prey species to extinction, leaving predator as the sole surviving species. Further, we observe that a time-periodic environment significantly affects oscillatory patterns, driving transitions between uniform bulk oscillations and oscillating Turing patterns. Overall, our study highlights the crucial influence of time-periodic environmental factors on prey-predator dynamics, considering prey refuge and additional food for predators, and stresses the need to account for such variability in ecological systems.</p></div>","PeriodicalId":792,"journal":{"name":"The European Physical Journal Plus","volume":"140 4","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143861140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The new higher-order generalized uncertainty principle and Big Bang nucleosynthesis 新的高阶广义测不准原理与大爆炸核合成
IF 2.8 3区 物理与天体物理
The European Physical Journal Plus Pub Date : 2025-04-22 DOI: 10.1140/epjp/s13360-025-06223-1
Song-Shan Luo, Qing-Quan Jiang, Zhong-Wen Feng, Xia Zhou, Xue-Lin Mu
{"title":"The new higher-order generalized uncertainty principle and Big Bang nucleosynthesis","authors":"Song-Shan Luo,&nbsp;Qing-Quan Jiang,&nbsp;Zhong-Wen Feng,&nbsp;Xia Zhou,&nbsp;Xue-Lin Mu","doi":"10.1140/epjp/s13360-025-06223-1","DOIUrl":"10.1140/epjp/s13360-025-06223-1","url":null,"abstract":"<div><p>The generalized uncertainty principle (GUP), as a key model in quantum gravity, is crucial for exploring cosmological properties and related challenges. In this paper, we investigate the effects of a higher-order GUP on primordial Big Bang nucleosynthesis (BBN). First, using a new higher-order GUP, we derive the modified Friedmann equations and the corresponding thermodynamic properties of the universe within the quantum gravity framework. Next, we analyze BBN under these modifications. Finally, by incorporating observational data of BBN and the primordial light element abundances, respectively, we establish constraints on the GUP parameter. The results reveal a significant impact of the GUP on the BBN processes in the early universe. Notably, the GUP parameter is found to take both positive and negative values, which is different from the classical case.</p></div>","PeriodicalId":792,"journal":{"name":"The European Physical Journal Plus","volume":"140 4","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143861139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Scalar beam propagation in a Lorentz-violating background 违反洛伦兹背景下的标量光束传播
IF 2.8 3区 物理与天体物理
The European Physical Journal Plus Pub Date : 2025-04-22 DOI: 10.1140/epjp/s13360-025-06262-8
C. A. Escobar, A. Martín-Ruiz, M. Mondragón, R. Jáuregui
{"title":"Scalar beam propagation in a Lorentz-violating background","authors":"C. A. Escobar,&nbsp;A. Martín-Ruiz,&nbsp;M. Mondragón,&nbsp;R. Jáuregui","doi":"10.1140/epjp/s13360-025-06262-8","DOIUrl":"10.1140/epjp/s13360-025-06262-8","url":null,"abstract":"<div><p>We investigate the propagation characteristics of apertured Gaussian and Bessel beams in a nontrivial spacetime background characterized by a constant 4-vector. Such 4-vector introduces a privileged direction in spacetime, thus breaking Lorentz invariance. The scalar beam is modeled by a massless scalar field theory, which corresponds to the scalar sector of the standard model extension. Assuming an axially symmetric Lorentz-violating background, we employ the Green’s function method to investigate the propagated field for particular input fields. We investigate the impact of the Lorentz-violating parameter upon the intensity and focalization of the beams. Finally, we discuss possible realizations in optically transparent multiferroic materials.</p></div>","PeriodicalId":792,"journal":{"name":"The European Physical Journal Plus","volume":"140 4","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1140/epjp/s13360-025-06262-8.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143861100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thermal performance of octadecane as phase change materials in circular tube applying molecular dynamics simulation: the effect of initial temperature 应用分子动力学模拟十八烷相变材料在圆管内的热性能:初始温度的影响
IF 2.8 3区 物理与天体物理
The European Physical Journal Plus Pub Date : 2025-04-22 DOI: 10.1140/epjp/s13360-025-06246-8
Mohammad Arabie, Davood Toghraie, Majid Riahi Samani, Mojtaba Haratian, Farshid Aghadavoudi
{"title":"Thermal performance of octadecane as phase change materials in circular tube applying molecular dynamics simulation: the effect of initial temperature","authors":"Mohammad Arabie,&nbsp;Davood Toghraie,&nbsp;Majid Riahi Samani,&nbsp;Mojtaba Haratian,&nbsp;Farshid Aghadavoudi","doi":"10.1140/epjp/s13360-025-06246-8","DOIUrl":"10.1140/epjp/s13360-025-06246-8","url":null,"abstract":"<div><p>This study examines the thermal properties of phase change materials (PCMs) using molecular dynamics simulation, concentrating on a cylindrical system including octadecane and water as PCMs. The study was executed in two phases: atomic structure equilibration and thermal analysis. During equilibration, the system's potential and total energy reached stability at 10 ns, confirming thermodynamic equilibrium for future study. The thermal analysis phase investigated the impact of altering the initial temperature (IT) on the system's charging and discharging behavior. Raising the initial temperature from 300 to 350 K resulted in a decrease in charging time, from 6.58 to 6.16 ns, attributable to improved atomic mobility and increased frequency of atomic collisions. At elevated temperatures, atoms gain more kinetic energy, promoting accelerated energy transfer and enhanced energy absorption efficiency. The raised temperature induced alterations in the system's atomic characteristics: atomic density diminished owing to thermal expansion, while the average atomic velocity and system temperature escalated in reaction to heightened atomic energy. Furthermore, the elevated temperature enhanced the thermal efficiency of the system, as seen by augmented heat flow and thermal conductivity. These enhancements resulted from accelerated atomic motion and more effective energy dispersion inside the material. The study shows that elevating the initial temperature significantly improved the thermal efficiency of PCM systems, providing critical insights for the optimization of thermal storage and heat management systems.</p></div>","PeriodicalId":792,"journal":{"name":"The European Physical Journal Plus","volume":"140 4","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143861098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analytical and numerical investigations of optimal control techniques for managing Ebola virus disease 埃博拉病毒疾病管理优化控制技术的分析和数值研究
IF 2.8 3区 物理与天体物理
The European Physical Journal Plus Pub Date : 2025-04-22 DOI: 10.1140/epjp/s13360-025-06251-x
W. Ahmad, H. Ullah, M. Rafiq, A. I. K. Butt, N. Ahmad
{"title":"Analytical and numerical investigations of optimal control techniques for managing Ebola virus disease","authors":"W. Ahmad,&nbsp;H. Ullah,&nbsp;M. Rafiq,&nbsp;A. I. K. Butt,&nbsp;N. Ahmad","doi":"10.1140/epjp/s13360-025-06251-x","DOIUrl":"10.1140/epjp/s13360-025-06251-x","url":null,"abstract":"<div><p>Ebola virus disease, often referred to as Ebola hemorrhagic fever, is one of the deadliest viral infections, posing a severe global health threat. It typically originates from human contact with domestic or wild animals and spreads through direct and indirect human contact, making containment highly challenging. Managing and controlling the spread of Ebola disease remains a significant challenge in epidemic response efforts. This study introduces a novel compartmental model to examine Ebola disease transmission dynamics and the effectiveness of control strategies. We conduct a mathematical analysis to ensure the model’s well-posedness and explore its stability properties. The theoretical results are verified using three numerical methods: the Euler’s method, the fourth-order Runge–Kutta method, and the non-standard-finite-difference method. Furthermore, the impact of time-invariant vaccination and quarantine rates on the epidemic is analyzed using the non-standard-finite-difference approach. A sensitivity analysis is conducted on the model to identify the most influential parameters affecting disease transmission. Additionally, we formulate an optimal control problem to identify effective, time-dependent strategies for Ebola vaccination and quarantine measures. As a novel contribution, our findings emphasize the potential of these control strategies in reducing both infection rates and associated costs, with a particular focus on the most reliable non-standard finite difference scheme. The application of forward and backward-in-time non-standard finite difference method ensures numerical stability and preserves essential biological properties. Numerical simulations demonstrate that a combination of effective vaccination and quarantine measures, and public awareness can accelerate the control of Ebola virus disease. Overall, this study provides a comprehensive approach to modeling, analyzing, and controlling Ebola virus disease by integrating advanced mathematical techniques with practical disease management strategies.</p></div>","PeriodicalId":792,"journal":{"name":"The European Physical Journal Plus","volume":"140 4","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143861395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信