{"title":"A gastrin-producing adrenal tumor?","authors":"J A Petrek, E L Bradley","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A patient with intractable diarrhea was found to have hyperchlorhydria, hypergastrinemia, and an increase in serum gastrin in response to secretin. At surgery the pancreas was completely normal, and an 8-cm adrenal adenoma was removed. Postoperatively the diarrhea ceased, and serum gastrin and gastric acid levels returned to normal. Tissue gastrin levels in the adrenal tumor were 1,000 times the expected values. Circumstantial evidence suggests that this tumor may have been secreting gastrin.</p>","PeriodicalId":79268,"journal":{"name":"Surgical gastroenterology","volume":"3 1","pages":"27-9"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17579266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Spontaneous perforation of the common hepatic duct: report of seven cases.","authors":"C S Chu","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Spontaneous perforation of the common hepatic duct is rare. Only 11 cases have been reported since McWilliams reported the first in 1912. Herewith, seven patients with spontaneous perforation of the hepatic duct treated between 1953-1980 at the Hunan Medical College Hospital in Ghangsha, China are added.</p>","PeriodicalId":79268,"journal":{"name":"Surgical gastroenterology","volume":"3 1","pages":"69-76"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17579271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Response of gastric acid and gut hormones in biliary tract reconstruction using an interposed jejunum or ileum in dogs.","authors":"M Imamura, I Sasaki, J Kameyama, T Sato","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Ten dogs were used to investigate the changes in gut hormones; gastrin, secretin, GIP, and gut-GLI, as well as gastric acid secretion after a test-meal loading following a cholecystoduodenostomy interposing a portion of the jejunum or the ileum. Although the changes in the response of plasma gut hormones to the test-meal were observed, the amount of acid output after the biliary tract reconstruction did not differ from that before the operations in either the jejunal interposition cholecystoduodenostomy or the ileal interposition cholecystoduodenostomy. Therefore, from the standpoint of gastric acid secretion, they are both recommendable procedures for biliary tract reconstruction. It was difficult, however, to interpret the change of gut hormone release in relation to gastric acid secretion. It is presumed that the release of gut hormones after the reconstructive procedure is mainly affected by the part of the small intestine which is used for the reconstruction.</p>","PeriodicalId":79268,"journal":{"name":"Surgical gastroenterology","volume":"3 1","pages":"51-8"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17579269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Endoscopic papillotomy (EPT) in acute obstructive suppurative cholangitis.","authors":"J H Solhaug, A R Rosseland","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Eight high risk patients, median age 79 years, with a distal obstruction of the common bile duct and serious clinical symptoms of acute obstructive cholangitis were treated by EPT. In seven patients, impaction of a stone in the common bile duct was found and in one patient, an obstructing cancer. EPT was performed without immediate complications and followed by obvious drainage of purulent bile in all patients. Repapillotomy with stone extraction was necessary in three patients 5, 6, and 10 days after the first EPT. The papillotomy was followed by immediate symptom relief, normalization of body temperature, and a decrease in leukocytes and bilirubin and alkaline phosphatase values within the first several postoperative days. Average hospitalization time was 8 days, ranging from 4-17 days. The patient with pancreatic cancer died 3 months after the EPT. One other patient died in pseudomonas sepsis 17 days after an uncomplicated EPT. ERCP controls in the other six patients have been normal and they all remain symptom free. Since early decompression is mandatory in these patients and laparotomy with internal decompression is associated with a high morbidity and mortality, endoscopic decompression should probably be the recommended treatment in patients with obstructive, septic cholangitis prior to employing this therapeutic option.</p>","PeriodicalId":79268,"journal":{"name":"Surgical gastroenterology","volume":"3 2","pages":"3-7"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17602026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Are acid and pepsin reduction the only effects of highly selective vagotomy. Evidence of changes in tissue levels of gastrin, prostaglandins and lysosomal acid hydrolases in an experimental ulcer model.","authors":"A Hall, R Hickman, J Terblanche","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Using the bile duct ligated (BDL) pig as a model of experimental peptic ulceration, a study was made of the effects of highly selective vagotomy (HSV) upon basal and stimulated acid and pepsin secretion, tissue levels of n-acetylglucosaminidase, prostaglandins (PgE2) and gastrin, and gastric venous plasma gastrin. In addition to reducing basal acid and pepsin output, HSV was found to return towards normal the elevated tissue prostaglandin and depressed antral gastrin levels after BDL. In addition, it was observed that gastric juice specimens were markedly viscid. It is suggested that there may be effects of HSV other than acid and pepsin reduction which require attention.</p>","PeriodicalId":79268,"journal":{"name":"Surgical gastroenterology","volume":"3 2","pages":"34-40"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17500966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Preoperative percutaneous transhepatic drainage: use or abuse. A clinical review.","authors":"D J Gouma, F G Moody","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The benefit of preoperative percutaneous transhepatic biliary drainage in patients with obstructive jaundice was reviewed in the literature from 1974 to July 1984. The role of preoperative drainage cannot be definitively assessed. Significant reduction of morbidity and mortality has been reported in some non-controlled studies; however, no benefit of preoperative \"external\" drainage was found in the only two reported randomized studies. At the present time external preoperative drainage cannot be advised routinely and the hazards of this technique and effect of bile losses may outweigh the benefits. The benefits of preoperative internal drainage without bile loss and closing of the enterohepatic cycle needs to be evaluated both percutaneously and endoscopically. Criteria, developed after specific identification of high risk patients, should be used to select patients for biliary drainage and to evaluate results of drainage studies. The clinical well-accepted drainage period of 2-4 weeks is controversial and the optimum period of drainage also requires further evaluation. The percutaneous approach carries significant morbidity and mortality.</p>","PeriodicalId":79268,"journal":{"name":"Surgical gastroenterology","volume":"3 2","pages":"74-80"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17500968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"From Krankenhaus to L.A.: pathways of progress in pancreatoduodenectomy.","authors":"J W Braasch","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":79268,"journal":{"name":"Surgical gastroenterology","volume":"3 1","pages":"3-12"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17453623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J P Arnaud, P Dumont, M Adloff, A Leguillou, J M Py
{"title":"Natural history of colorectal carcinoma with untreated liver metastases.","authors":"J P Arnaud, P Dumont, M Adloff, A Leguillou, J M Py","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In a series of 474 patients operated on for colonic and rectal carcinoma, 65 were shown to have hepatic metastases. Factors influencing spontaneous survival were evaluated in 56 patients. This study emphasizes the dominant role of the amount of liver involvement. A clinical staging referring to the size and number of liver deposits, to the presence or absence of jaundice and/or malignant ascites, and to liver function tests abnormalities provides an available classification which can be closely related to the outcome of such patients. Thus, it yields a valuable basis to avoid misleading prognostic data and to substantiate the effectiveness of aggressive treatments in case of carefully selected patients.</p>","PeriodicalId":79268,"journal":{"name":"Surgical gastroenterology","volume":"3 1","pages":"37-42"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17579267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The effect of celiac and superior mesenteric ganglionectomy on the canine gastric mucosal barrier.","authors":"M T Dayton, J F Schlegel, C F Code","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The role of the sympathetic nervous system in gastric function remains poorly understood. This study was designed to evaluate the effect of celiac and superior mesenteric ganglionectomy on gastric mucosal barrier function. Four dogs with Pavlov-type pouches were studied. In the preganglionectomy phase, the pouch gastric mucosa was challenged with progressively higher concentrations of known damaging agents, ethanol and taurocholic acid. Mucosal integrity was studied by measuring ionic fluxes (H+, Na+, K+, Cl-) and transmucosal electrical potential difference (PD). Celiac and superior mesenteric ganglionectomy was then performed and after adequate recovery, the postganglionectomy phase of the study was done challenging the mucosa with the same damaging agents at the same concentrations used in the preganglionectomy study. The major alterations which occurred postganglionectomy were primarily motility-related and little evidence of altered gastric mucosal barrier permeability was detected. Specifically, all four animals developed an intractable diarrhea postganglionectomy which resulted in a 20% weight loss over 4-6 weeks. In contrast, there was no significant difference in H+ loss from and Na+/K+ gain to the pouches when the pre- and postganglionectomy fluxes were compared. Similarly, after challenge with damaging agents, PD changes in the pre- and postganglionectomy were not significantly different.</p>","PeriodicalId":79268,"journal":{"name":"Surgical gastroenterology","volume":"3 1","pages":"63-7"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17579270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The SSAT-AGA (Society for Surgery of the Alimentary Tract-American Gastroenterological Association). New Orleans, May 20-23, 1984.","authors":"S W Ashley, L Y Cheung","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":79268,"journal":{"name":"Surgical gastroenterology","volume":"3 2","pages":"47-53"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17500967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}