{"title":"高度选择性迷走神经切开术的唯一效果是酸和胃蛋白酶减少吗?实验性溃疡模型中胃泌素、前列腺素和溶酶体酸水解酶组织水平变化的证据。","authors":"A Hall, R Hickman, J Terblanche","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Using the bile duct ligated (BDL) pig as a model of experimental peptic ulceration, a study was made of the effects of highly selective vagotomy (HSV) upon basal and stimulated acid and pepsin secretion, tissue levels of n-acetylglucosaminidase, prostaglandins (PgE2) and gastrin, and gastric venous plasma gastrin. In addition to reducing basal acid and pepsin output, HSV was found to return towards normal the elevated tissue prostaglandin and depressed antral gastrin levels after BDL. In addition, it was observed that gastric juice specimens were markedly viscid. It is suggested that there may be effects of HSV other than acid and pepsin reduction which require attention.</p>","PeriodicalId":79268,"journal":{"name":"Surgical gastroenterology","volume":"3 2","pages":"34-40"},"PeriodicalIF":0.0000,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Are acid and pepsin reduction the only effects of highly selective vagotomy. Evidence of changes in tissue levels of gastrin, prostaglandins and lysosomal acid hydrolases in an experimental ulcer model.\",\"authors\":\"A Hall, R Hickman, J Terblanche\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Using the bile duct ligated (BDL) pig as a model of experimental peptic ulceration, a study was made of the effects of highly selective vagotomy (HSV) upon basal and stimulated acid and pepsin secretion, tissue levels of n-acetylglucosaminidase, prostaglandins (PgE2) and gastrin, and gastric venous plasma gastrin. In addition to reducing basal acid and pepsin output, HSV was found to return towards normal the elevated tissue prostaglandin and depressed antral gastrin levels after BDL. In addition, it was observed that gastric juice specimens were markedly viscid. It is suggested that there may be effects of HSV other than acid and pepsin reduction which require attention.</p>\",\"PeriodicalId\":79268,\"journal\":{\"name\":\"Surgical gastroenterology\",\"volume\":\"3 2\",\"pages\":\"34-40\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1984-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Surgical gastroenterology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Surgical gastroenterology","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Are acid and pepsin reduction the only effects of highly selective vagotomy. Evidence of changes in tissue levels of gastrin, prostaglandins and lysosomal acid hydrolases in an experimental ulcer model.
Using the bile duct ligated (BDL) pig as a model of experimental peptic ulceration, a study was made of the effects of highly selective vagotomy (HSV) upon basal and stimulated acid and pepsin secretion, tissue levels of n-acetylglucosaminidase, prostaglandins (PgE2) and gastrin, and gastric venous plasma gastrin. In addition to reducing basal acid and pepsin output, HSV was found to return towards normal the elevated tissue prostaglandin and depressed antral gastrin levels after BDL. In addition, it was observed that gastric juice specimens were markedly viscid. It is suggested that there may be effects of HSV other than acid and pepsin reduction which require attention.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
