Clinical and experimental hypertension. Part B, Hypertension in pregnancy最新文献_第2页

Urine dopamine during normotensive and hypertensive pregnancies and the puerperium. 正常妊娠和高血压妊娠及产褥期尿多巴胺的变化。

Clinical and experimental hypertension. Part B, Hypertension in pregnancy Pub Date : 1983-01-01 DOI: 10.3109/10641958309006090

R Huss, K W Hancock, G F Cope, M R Lee

引用次数: 5

Renin and aldosterone concentrations in pregnant essential hypertensives - a prospective study. 妊娠期原发性高血压患者肾素和醛固酮浓度的前瞻性研究。

Clinical and experimental hypertension. Part B, Hypertension in pregnancy Pub Date : 1983-01-01 DOI: 10.3109/10641958309006085

F Broughton Pipkin, E M Symonds, G D Lamming, F A Jadoul

{"title":"Renin and aldosterone concentrations in pregnant essential hypertensives - a prospective study.","authors":"F Broughton Pipkin, E M Symonds, G D Lamming, F A Jadoul","doi":"10.3109/10641958309006085","DOIUrl":"https://doi.org/10.3109/10641958309006085","url":null,"abstract":"Serial blood samples were obtained throughout pregnancy from 11 women with essential hypertension (EHT). Seven were treated with labetalol (Trandate) and 4 with alpha -methyl dopa (Aldomet). Nine patients were well-controlled throughout pregnancy. Their mean plasma renin concentrations (PRC) followed the profile determined in 18 normal patients studied serially. They remained in the upper normal range until the last month, when both treatment groups showed a fall in PRC. Mean plasma aldosterone (ALD) also followed a normal profile until late gestation when it too showed a sharp fall. Of the two patients who developed superimposed PIH, one, who received labetalol, developed severe hypertension at 35 weeks, requiring delivery. Although PRC increased early in this pregnancy, ALD did not, remaining low throughout. Serum potassium [K+] measurements were also very low in this patient. The second patient only became hypertensive at 40 weeks and had PRC and ALD profiles resembling those in the successfully treated EHTs. There was a strong positive correlation throughout between serum potassium and ALD measurements (p less than 0.001) but none between PRC and ALD. This latter agrees with the known lack of correlation between PRC and ALD in normal pregnancy and may suggest that changes in electrolyte balance are more important stimuli to ALD secretion during pregnancy.","PeriodicalId":79209,"journal":{"name":"Clinical and experimental hypertension. Part B, Hypertension in pregnancy","volume":"2 2","pages":"255-69"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10641958309006085","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17408244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

The effects of anesthesia and mode of delivery on the parameters of the renin-angiotensin system. 麻醉和给药方式对肾素-血管紧张素系统参数的影响。

Clinical and experimental hypertension. Part B, Hypertension in pregnancy Pub Date : 1983-01-01 DOI: 10.3109/10641958309023461

C A Samaras, F Broughton Pipkin, E M Symonds

{"title":"The effects of anesthesia and mode of delivery on the parameters of the renin-angiotensin system.","authors":"C A Samaras, F Broughton Pipkin, E M Symonds","doi":"10.3109/10641958309023461","DOIUrl":"https://doi.org/10.3109/10641958309023461","url":null,"abstract":"Paired maternal venous (MV) before (P1) and after (P2) general anesthesia, cord venous (CV) and cord arterial (CA) blood was taken from two groups of primagravid women, one delivered vaginally and the other by elective lower segment Caesarian section (ELSCS). ACTH, Cortisol (CoSol) Aldosterone (Aldo) Plasma Renin Activity (PRA) Plasma Renin Concentration (PRC) Angiotensin II (AII) Solium (N alpha) and Potassium [K]+ were measured in both study groups. Of the various hormones studied, all but cortisol were raised in the P2 sample with only ACTH and AII achieving significant increase. A number of significant positive correlations was found between P1 and P2 samples as well as between the hormones themselves. Four of the vaginally delivered group received epidural analgesia and demonstrated significantly higher levels of ACTH and CoSol in the CV sample. A comparison of the studied variables between the two groups showed a significant decrease in the ELSCS group of ACTH and CoSol in the MV sample, of ACTH, CoSol, PRC in the CV sample, and of CoSol in the CA sample. Of all the parameters, studied, only [K]+ together with Aldo was found to be elevated in the CV sample of the ELSCS group but only [K]+ achieved significant increase.","PeriodicalId":79209,"journal":{"name":"Clinical and experimental hypertension. Part B, Hypertension in pregnancy","volume":"2 1","pages":"83-93"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10641958309023461","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17368539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Observations on clotting activity during pre-eclampsia. 子痫前期凝血活性的观察。

Clinical and experimental hypertension. Part B, Hypertension in pregnancy Pub Date : 1983-01-01 DOI: 10.3109/10641958309006078

C D Lox, M M Dorsett, R M Hampton

引用次数: 16

Plasma antithrombin III levels in pre-eclampsia. 子痫前期血浆抗凝血酶III水平。

Clinical and experimental hypertension. Part B, Hypertension in pregnancy Pub Date : 1983-01-01 DOI: 10.3109/10641958309023467

G H Weenink, P E Treffers, P Vijn, M E Smorenberg-Schoorl, J W ten Cate

引用次数: 11

Hemodynamic changes after chronic pindolol administration in pregnant renal hypertensive rats. 慢性品多洛尔对妊娠肾性高血压大鼠血流动力学的影响。

Clinical and experimental hypertension. Part B, Hypertension in pregnancy Pub Date : 1983-01-01 DOI: 10.3109/10641958309023454

Y Lundgren, U Ljungblad, K Karlsson

{"title":"Hemodynamic changes after chronic pindolol administration in pregnant renal hypertensive rats.","authors":"Y Lundgren, U Ljungblad, K Karlsson","doi":"10.3109/10641958309023454","DOIUrl":"https://doi.org/10.3109/10641958309023454","url":null,"abstract":"The aim of the present study on pregnant renal hypertensive rats was to investigate the effects on central hemodynamics and uteroplacental blood flow after chronic administration of pindolol, a nonspecific beta-adrenergic receptor blocking agent with intrinsic beta-stimulatory effect. Renal hypertension was induced by partial clamping of both renal arteries four weeks before pregnancy. Pindolol was administered with the food during the entire pregnancy period. Two to four days before expected delivery mean arterial pressure, heart rate, cardiac output, (dye-dilution technique) and utero-placental blood supply (microsphere technique) were determined. The chronic pindolol treatment reduced heart rate by 25 per cent while both mean arterial pressure and cardiac output remained unchanged. However, blood flow to uterus and placentae was reduced by 43 and 64 per cent, respectively, after pindolol treatment. Clinical as well as experimental studies (15, 16) demonstrate a reduced utero-placental blood supply when pregnancies are complicated by hypertension. As pregnancies with severe hypertension are associated with an increased frequency of intrauterine growth retardation and intrauterine asphyxia the present results indicate that the combination of hypertension and long-term treatment with beta-blockers might reduce utero-placental blood flow enough as to seriously interfere with fetal oxygen supply thereby increasing the risk of intra- and extra-uterine asphyxia.","PeriodicalId":79209,"journal":{"name":"Clinical and experimental hypertension. Part B, Hypertension in pregnancy","volume":"2 1","pages":"1-14"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10641958309023454","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17923168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Renal histology and pregnancy performance in systemic lupus erythematosus. 系统性红斑狼疮的肾脏组织学和妊娠表现。

Clinical and experimental hypertension. Part B, Hypertension in pregnancy Pub Date : 1983-01-01 DOI: 10.3109/10641958309006091

L D Devoe, G L Loy, B H Spargo

{"title":"Renal histology and pregnancy performance in systemic lupus erythematosus.","authors":"L D Devoe, G L Loy, B H Spargo","doi":"10.3109/10641958309006091","DOIUrl":"https://doi.org/10.3109/10641958309006091","url":null,"abstract":"Previous reports indicate that maternal and fetal outcome in pregnancies complicated by systemic lupus erythematosus (SLE) may be strongly influenced by the presence of renal disease. As the relationship between renal histology and clinical function in SLE is not consistent, prospective data on the outcomes of such pregnancies would aid patient counselling. Fifteen women with SLE had 18 pregnancies subsequent to renal biopsies, performed from 3 months to 8 years prior to conception. Their renal function was evaluated before, during and after pregnancy. Fourteen of 15 patients had evidence of renal involvement, based on by light and electron microscopic sections: 7 had mesangial involvement (WHO Class II); 5 had active focal or diffuse glomerulonephritis (Classes III and IV); two had membranous involvement (Class V); 1, no evident disease. Perinatal outcome was similar whether lesions were milder (8 continuing pregnancies, 4 term deliveries) or more severe (6 continuing pregnancies, 3 term deliveries). Clinical renal function was normal in all but 3 cases at the beginning of pregnancy; 2 additional patients experienced moderate deteriorations in renal function during pregnancy but recovered normal function in the puerperium. Fetal outcome was abnormal (3 premature deliveries, 1 neonatal death, 1 spontaneous abortion) in all cases where renal function was decreased, while 10 of 13 pregnancies in patients with normal renal function ended in term deliveries. The data suggest that currently preconceptual renal histology provides a less accurate basis for perinatal counselling than does the assessment of clinical renal function.","PeriodicalId":79209,"journal":{"name":"Clinical and experimental hypertension. Part B, Hypertension in pregnancy","volume":"2 2","pages":"325-40"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10641958309006091","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17922085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Albumin therapy and intrauterine growth retardation in gestosis. 妊娠期白蛋白治疗与宫内生长迟缓。

Clinical and experimental hypertension. Part B, Hypertension in pregnancy Pub Date : 1983-01-01 DOI: 10.3109/10641958309023457

T Kaneoka, S Taguchi, K Shirakawa

引用次数: 0

Propranolol in pregnancy three year prospective study. 心得安对妊娠期3年的前瞻性研究。

Clinical and experimental hypertension. Part B, Hypertension in pregnancy Pub Date : 1983-01-01 DOI: 10.3109/10641958309006092

I Livingstone, P W Craswell, E B Bevan, M T Smith, M J Eadie

引用次数: 34

Diagnosis and treatment of pregnancy induced platelet dysfunction. 妊娠致血小板功能障碍的诊断与治疗。

Clinical and experimental hypertension. Part B, Hypertension in pregnancy Pub Date : 1983-01-01 DOI: 10.3109/10641958309023455

R C Goodlin, R B Davis

引用次数: 4