{"title":"The hematocrit-electrolyte-concentration-apparatus (HECA).","authors":"H Kiesewetter, C Mrowietz, H Lazar, F Jung","doi":"10.3233/bir-1984-23s128","DOIUrl":"https://doi.org/10.3233/bir-1984-23s128","url":null,"abstract":"<p><p>An instrument was developed which can simultaneously determine the hematocrit and the total electrolyte concentration in blood and plasma respectively. It is possible to correct the hematocrit value for fluctuations of the total electrolyte concentration. Pilot studies of this device have been conducted on physiological and rigid erythrocyte suspensions and on plasma with various total electrolyte concentration. In the future, this device will be employed in analyzing blood and plasma of patients undergoing hemodialysis.</p>","PeriodicalId":79205,"journal":{"name":"Biorheology. Supplement : the official journal of the International Society of Biorheology","volume":"1 ","pages":"155-7"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3233/bir-1984-23s128","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17647988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Some new developments in the rheology of bone.","authors":"M Johnson, J L Katz","doi":"10.3233/bir-1984-23s130","DOIUrl":"https://doi.org/10.3233/bir-1984-23s130","url":null,"abstract":"<p><p>Bone has been shown to be a viscoelastic material which is thermorheologically complex. This implies that multiple mechanisms determine the viscoelastic response of bone. New calculations of the contribution of fluid flow to the viscoelastic behavior of bone have been made. The calculation of the relaxation time was based on Biot's model for the relaxation of fluid flow in porous materials while the relaxation strength was estimated from simple composite models. These models together with recent measurements of the permeability of bone predict that part of the relaxation due to fluid flow will occur at fairly high frequencies, perhaps above 10 kHz for in vitro samples. Measurements of ultrasonic wave propagation and attenuation in wet bone have been performed from 0.5 MHz to 15 MHz and the mechanical damping was measured from 100 Hz to 1 kHz with fluid viscosities ranging from 10(-3) to 5 X 10(-2) (MKS). However, a complete understanding of the rheological properties of bone will require additional experiments to bridge the gap between the low frequency measurements and the ultrasonic measurements.</p>","PeriodicalId":79205,"journal":{"name":"Biorheology. Supplement : the official journal of the International Society of Biorheology","volume":"1 ","pages":"169-74"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3233/bir-1984-23s130","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17647990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P Lorente, I Azancot, C Masquet, J L Adda, R Saumont, R Slama
{"title":"Comparison of geometrical models for evaluating left ventricular wall motion from cineangiograms.","authors":"P Lorente, I Azancot, C Masquet, J L Adda, R Saumont, R Slama","doi":"10.3233/bir-1984-23s131","DOIUrl":"https://doi.org/10.3233/bir-1984-23s131","url":null,"abstract":"<p><p>Regional wall motion of the left ventricle (LV) has been analyzed from contrast ventriculograms by using 4 methods based on different geometrical frameworks. Two of them utilize moving internal reference systems, the center of mass (CMM) and the long axis (LAM) methods; the two other ones use fixed external reference systems, the area-based (ABM) and the Palo Alto (PAM) methods. The techniques were applied on a set of 81 patients: 42 were normal and composed the group I; 22 had a single vessel obstruction greater than 75% of the left anterior descending coronary artery (group II) with old necrosis or active ischemia of the LV anterior wall; 17 had a single vessel obstruction greater than 75% of the right coronary artery (group III) with old necrosis or active ischemia of the LV inferior wall. ABM and PAM showed the highest specificities and sensitivities on the studied sample. Therefore, we believe these two methods, of the techniques tested, are the best to quantitate wall motion from cineangiograms.</p>","PeriodicalId":79205,"journal":{"name":"Biorheology. Supplement : the official journal of the International Society of Biorheology","volume":"1 ","pages":"175-82"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3233/bir-1984-23s131","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17647991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C Duvivier, J P Arnould, E Malher, C Fourneau, J F Stoltz
{"title":"A technique for continuously measuring filtration resistance at constant pressure.","authors":"C Duvivier, J P Arnould, E Malher, C Fourneau, J F Stoltz","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A device for continuously measuring, at constant pressure, the filtration resistance of different liquid suspensions is described. It is made up of two main parts: flowmeter system and electronic circuit. The flowmeter consists of a capillary tube and a sensitive pressure transducer, and has a time response of 100 ms and a linearity of +/- 1% from 1 uls-1. The electronic part allows the calculation and recording of flow versus time and filtration resistance versus the volume which passes through the filter. Principle, technical characteristics of the system and examples of recording with several Red Blood Cell populations are reported.</p>","PeriodicalId":79205,"journal":{"name":"Biorheology. Supplement : the official journal of the International Society of Biorheology","volume":"1 ","pages":"271-4"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17298982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y Isogai, T Yokose, T Maeda, M Akiyama, S Onogi, T Masuda, T Ohmachi, S Iwamoto
{"title":"The OP-Rheometer system, a new device for analysis of viscosity and viscoelasticity of blood: description and clinical application.","authors":"Y Isogai, T Yokose, T Maeda, M Akiyama, S Onogi, T Masuda, T Ohmachi, S Iwamoto","doi":"10.3233/bir-1984-23s106","DOIUrl":"https://doi.org/10.3233/bir-1984-23s106","url":null,"abstract":"<p><p>OP-Rheometer is a rotational viscometer of concentric type, which was developed to measure blood viscosity at low shear rate (0.2-40 sec-1) and viscoelasticity at 0.1-3.0 Hz in the context of clinical medicine. This system consists of a mechanical unit, a control unit (console), a data processing unit and a printer. The dynamic or steady state flow data are automatically printed out. An outer cylinder (sample container) is connected to a torsion wire assembly supported by a pair of magnetic bearings. The angular displacement is detected by a pair of variable differential transformers. In clinical application of this rheometer, authours have confirmed that the viscosity and viscoelasticity of blood from diabetic patients are higher than for normal subjects.</p>","PeriodicalId":79205,"journal":{"name":"Biorheology. Supplement : the official journal of the International Society of Biorheology","volume":"1 ","pages":"35-41"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3233/bir-1984-23s106","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17647685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C Duvivier, J Didelon, J P Arnould, J M Zahm, E Puchelle, C Kopp, B Obrecht
{"title":"A new viscoelastometer for studying the rheological properties of bronchial mucus in clinical practice.","authors":"C Duvivier, J Didelon, J P Arnould, J M Zahm, E Puchelle, C Kopp, B Obrecht","doi":"10.3233/bir-1984-23s121","DOIUrl":"https://doi.org/10.3233/bir-1984-23s121","url":null,"abstract":"<p><p>In clinical practice, a wide variety of drugs are given to modify the rheological properties of bronchial mucus but they are frequently not correctly chosen because there is not a simple apparatus available for the routine measurement of the mucus viscoelasticity. We designed a new viscoelastometer which is easy to operate and permit accurate measurement of the viscoelastic properties of mucus. The system has a Couette geometry and requires a sample of 1 ml. The outer cylinder is thermostated and rotates at a constant rate. The resulting torque is measured on the inner cylinder using a microdisplacement transducer. The inner cylinder is suspended by a special wire system which maintains a constant 0.75 mm gap between the two cylinders. The apparent viscosity is calculated up to 100 Pa.s. at a low shear rate (0.4 s-1) and the elasticity is analyzed by a stress relaxation method. The characteristics of the apparatus and the typical viscoelasticity behaviour of several sputum samples are reported.</p>","PeriodicalId":79205,"journal":{"name":"Biorheology. Supplement : the official journal of the International Society of Biorheology","volume":"1 ","pages":"119-22"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3233/bir-1984-23s121","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17648311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dependency of red blood cell passage time on pore geometry in the single-pore erythrocyte rigidometer (SER).","authors":"D Seiffge","doi":"10.3233/bir-1984-23s142","DOIUrl":"https://doi.org/10.3233/bir-1984-23s142","url":null,"abstract":"<p><p>Employing the \"Singlepore Erythrocyte Rigidometer\" (SER) in which small pore diameters were used, significant differences were measured between red blood cells from adjuvant arthritic rats compared to control from non-diseased animals. The results changed to opposite values using higher pore diameters, which may be due to differences in cell \"rigidity\" and MCV.</p>","PeriodicalId":79205,"journal":{"name":"Biorheology. Supplement : the official journal of the International Society of Biorheology","volume":"1 ","pages":"245-7"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3233/bir-1984-23s142","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17392725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L Berga, J Dolz, J L Vives-Corrons, E Feliu, C Rozman
{"title":"Viscometric methods for assessing red cell deformability and fragmentation.","authors":"L Berga, J Dolz, J L Vives-Corrons, E Feliu, C Rozman","doi":"10.3233/bir-1984-23s153","DOIUrl":"https://doi.org/10.3233/bir-1984-23s153","url":null,"abstract":"<p><p>Erythrocyte deformability is an important determinant of red cell life span and depends on at least three key factors: shape, internal viscosity and membrane mechanical properties. In this paper we describe three viscometric methods for assessing red cell deformability and fragmentation: 1) Plasma and whole blood are sheared with a coneplate viscometer at high shear rates. A mathematical model for liquid behaviour is applied to the results from plasma and whole blood viscosity, and a rheological parameter called internal viscosity is obtained. 2) Shearing packed red cells (Haematocrit greater than or equal to 95%) at high shear rates, a mechanical fragmentation curve is obtained, and a new rheological parameter called rupture stress is determined. 3) Shearing whole blood at 230 Sec-1 and increasing continuously the temperature from 37 degrees C to 57 degrees C, a thermic curve is obtained. A viscosity increase is observed at about 48 degrees C and thermic curve changes are related to effects of heat on the red cell membrane. Internal viscosity, mechanical fragmentation curve and thermic curve assess red cell deformability and fragmentation and can be used as diagnostic tools in diseases with red cell abnormalities.</p>","PeriodicalId":79205,"journal":{"name":"Biorheology. Supplement : the official journal of the International Society of Biorheology","volume":"1 ","pages":"297-301"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3233/bir-1984-23s153","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17647767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M L Viriot, T Collin, S Gaillard, J F Stoltz, J C Andre
{"title":"Investigation of human blood platelets with fluorescence spectroscopy.","authors":"M L Viriot, T Collin, S Gaillard, J F Stoltz, J C Andre","doi":"10.3233/bir-1984-23s158","DOIUrl":"https://doi.org/10.3233/bir-1984-23s158","url":null,"abstract":"<p><p>Intramolecular excimer formation of dipyrenylpropane was investigated in human blood platelets. The ratio of the emission intensities of excimer to monomer (IE/IM) is sensitive to changes in lipidic membrane structure, induced by external perturbations, such as cholesteryl hemisuccinate introduction and temperature. Lack of reliable \"microviscosities\" determinations could be due to poor solubility of the probe in aqueous cells suspensions. Results were compared to those obtained with the fluorescence polarization technique.</p>","PeriodicalId":79205,"journal":{"name":"Biorheology. Supplement : the official journal of the International Society of Biorheology","volume":"1 ","pages":"331-3"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3233/bir-1984-23s158","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17647770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Harmonic and impulse rheological tests of biomaterials.","authors":"D Geiger, D Trevisan, M Bercovy, C Oddou","doi":"10.3233/bir-1984-23s133","DOIUrl":"https://doi.org/10.3233/bir-1984-23s133","url":null,"abstract":"<p><p>Up to now, not so much attention has been paid concerning the dynamic rheological behaviour of soft tissues although non linear viscoelastic effects have often been reported when mechanical properties of biomaterials are concerned. In order to characterize such properties different rheological tests have been proposed, the two principal being the study of the sample stresses responses to applied strains which are either harmonic with time or of step function type. Two different apparatus have been designed in our laboratory which allow specific rheological tests on biological materials under controlled environmental conditions. With one of them, harmonic uniaxial extension tests are performed in a large domain of frequencies (.001 Hz to 100 Hz) and forces (up to 20 daN); with the other, the samples are submitted to relaxation tests in uniaxial elongation up to 5 cm deformation within time duration of the order of 20 ms. The principal characteristics, limitations and performances of such apparatus are presented and few examples of data thus obtained are given. On the basis of quasi linear viscoelasticity models, it can be shown that both two types of tests with their proper limitations are leading to the same rheological parameters.</p>","PeriodicalId":79205,"journal":{"name":"Biorheology. Supplement : the official journal of the International Society of Biorheology","volume":"1 ","pages":"193-200"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3233/bir-1984-23s133","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17647856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}