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Biorheology. Supplement : the official journal of the International Society of Biorheology最新文献

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An improved filtration rate for measuring red cell deformability. 提高了测量红细胞变形能力的过滤率。
Biorheology. Supplement : the official journal of the International Society of Biorheology Pub Date : 1984-01-01 DOI: 10.3233/bir-1984-23s143
S O Sowemimo-Coker, I B Kovacs, P Turner, J D Kirby
{"title":"An improved filtration rate for measuring red cell deformability.","authors":"S O Sowemimo-Coker,&nbsp;I B Kovacs,&nbsp;P Turner,&nbsp;J D Kirby","doi":"10.3233/bir-1984-23s143","DOIUrl":"https://doi.org/10.3233/bir-1984-23s143","url":null,"abstract":"<p><p>In order to follow the filtration of a red cell suspension with time, the filtration technique described (1) has been modified. The red cell suspension is filtered through a polycarbonate membrane filter (pore diameter 5 micron) under gravitational force. The filtrate is collected in a plastic tube connected to an isometric transducer, the output of which is registered on a chart recorder. The linear part of the curve obtained is used to calculate the slope and the relative filterability (RF) ie the ratio of the rate of flow of the red cell suspension to the rate of flow of the suspending medium. The reproducibility of the technique is demonstrated by a less than 5% coefficient of variation in one blood sample less than 5% interobserver variation and a weekly variation from the same donor of less than 5%. The fast filtration rate of a highly diluted red cell suspension (0.5-1%) may be followed with this technique, taking the first 15 seconds to calculate it. The technique has proved useful in detecting differences in red cell deformability in connective tissue disorders (Scleroderma, Raynaud's phenomenon) also between stored and freshly prepared red cell suspension and its improvement by drugs (pentoxifylline, dipyridamole).</p>","PeriodicalId":79205,"journal":{"name":"Biorheology. Supplement : the official journal of the International Society of Biorheology","volume":"1 ","pages":"249-53"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3233/bir-1984-23s143","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17647864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Resonance thrombography. 共振thrombography。
Biorheology. Supplement : the official journal of the International Society of Biorheology Pub Date : 1984-01-01 DOI: 10.3233/bir-1984-23s104
H Hartert
{"title":"Resonance thrombography.","authors":"H Hartert","doi":"10.3233/bir-1984-23s104","DOIUrl":"https://doi.org/10.3233/bir-1984-23s104","url":null,"abstract":"<p><p>Resonance Thrombography is a method to follow up the coagulation process ex vivo from its very beginning up to its final consolidation phase resp. fibrinolysis. The mode of measurement is adopting the resonance effect of fibrin elasticity. The connection of a cylindric rod and outer cylinder by elastic fibrin fibres will increase the potential natural frequency (38 Hz) of the elastically suspended rod, to which a constant orbital drive of a very small radius is imported electronically. Change of difference between constant drive frequency and varying resonance frequency over time will result in sensitive registration of the Resonance Thrombogram (RTG). The orbital movement of the rod causes a circular flow of blood as long as it is fluid. The speed of flow is comparable to that in a medium sized vein, resembling a physiological situation. The clinical application of RTGraphy is regarding the fact, that there is practically no disturbance of clotting process which is not represented in any change of clot construction. Diagnosis of DIC, demonstration of SFMC as well as of fibrinolysis, differentiation between the effect of fibrin structure and of platelet activity are among the clinical assignments of RTGraphy.</p>","PeriodicalId":79205,"journal":{"name":"Biorheology. Supplement : the official journal of the International Society of Biorheology","volume":"1 ","pages":"15-22"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3233/bir-1984-23s104","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17647986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The missing negative effect of red cell aggregation upon blood flow in small capillaries at low shear forces. 在低剪切力下，红细胞聚集对小毛细血管血流的负面影响。
Biorheology. Supplement : the official journal of the International Society of Biorheology Pub Date : 1984-01-01 DOI: 10.3233/bir-1984-23s139
D Braasch
{"title":"The missing negative effect of red cell aggregation upon blood flow in small capillaries at low shear forces.","authors":"D Braasch","doi":"10.3233/bir-1984-23s139","DOIUrl":"https://doi.org/10.3233/bir-1984-23s139","url":null,"abstract":"<p><p>Flow resistance of EDTA or defibrinized blood was measured in a vertical capillary viscometer. (Capillary I.D. = 0.3 mm, 1 = 475 mm, tau w = 0.27 to 0.036 Pa). With decreasing shear forces the apparent viscosity increased from 12 to 16 mPa X s, i.e. by about 30%. There was no significant difference in flow resistance between red cells suspended in plasma or serum. The apparent viscosity of the same blood sample increased from 14 to 45 mPa X s for RBC in plasma i.e. by about 320% if measured with a rotational viscometer. The attempt is made to explain this difference in flow resistance with the different effect of shear resistant RBC-aggregates upon a parabolic streaming profile in a capillary, or upon the quasi linear profile within the annular gap of a rotational viscometer.</p>","PeriodicalId":79205,"journal":{"name":"Biorheology. Supplement : the official journal of the International Society of Biorheology","volume":"1 ","pages":"227-30"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3233/bir-1984-23s139","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17492624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Anticoagulants and erythrocyte filterability. 抗凝剂和红细胞滤过性。
Biorheology. Supplement : the official journal of the International Society of Biorheology Pub Date : 1984-01-01 DOI: 10.3233/bir-1984-23s149
J Stuart, G S Lucas, N M Caldwell, M W Kenny, M Meakin, M F Aillaud, I Juhan-Vague
{"title":"Anticoagulants and erythrocyte filterability.","authors":"J Stuart,&nbsp;G S Lucas,&nbsp;N M Caldwell,&nbsp;M W Kenny,&nbsp;M Meakin,&nbsp;M F Aillaud,&nbsp;I Juhan-Vague","doi":"10.3233/bir-1984-23s149","DOIUrl":"https://doi.org/10.3233/bir-1984-23s149","url":null,"abstract":"<p><p>Positive-pressure and initial-flow-rate (Hémorhéomètre) filtration systems were used to study the deformability of erythrocytes from whole blood stored in EDTA or heparin. When all contaminating platelets and leucocytes were removed from the erythrocyte suspension there was no significant anticoagulant effect on erythrocyte filtration. Blood may therefore be stored in K2EDTA (1.5 mg/ml blood) or lithium heparin (15 IU/ml blood) for up to 6 hours at room temperature prior to measurement of erythrocyte filterability.</p>","PeriodicalId":79205,"journal":{"name":"Biorheology. Supplement : the official journal of the International Society of Biorheology","volume":"1 ","pages":"279-81"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3233/bir-1984-23s149","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17492626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Dynamic evaluation of aggregation and agglutination of red blood cells. 红细胞聚集和凝集的动态评价。
Biorheology. Supplement : the official journal of the International Society of Biorheology Pub Date : 1984-01-01 DOI: 10.3233/bir-1984-23s107
M Kaibara, M Date, E Fukada
{"title":"Dynamic evaluation of aggregation and agglutination of red blood cells.","authors":"M Kaibara,&nbsp;M Date,&nbsp;E Fukada","doi":"10.3233/bir-1984-23s107","DOIUrl":"https://doi.org/10.3233/bir-1984-23s107","url":null,"abstract":"<p><p>Viscoelastic evaluation of aggregation and agglutination of red blood cells was attempted. A concentric double cylinder viscoelastometer was used for determining the dynamic rigidity modulus and loss modulus of blood sample. The dynamic rigidity modulus of horse blood were measured over a wide range of hematocrit. The relation between the viscoelastic behavior and the erythrocyte sedimentation was examined. The change in the amount of surface charge of enzyme treated red blood cells was qualitatively estimated from the measurements of dynamic viscoelasticity of red blood cells suspension with added poly-L-lysine. The dynamic rigidity modulus of red blood cells agglutinated by adding lectin (concanavalin A) were also measured.</p>","PeriodicalId":79205,"journal":{"name":"Biorheology. Supplement : the official journal of the International Society of Biorheology","volume":"1 ","pages":"43-7"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3233/bir-1984-23s107","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17647686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Studies of rheologically active biological macromolecules by quasielastic light scattering. 准弹性光散射研究具有流变活性的生物大分子。
Biorheology. Supplement : the official journal of the International Society of Biorheology Pub Date : 1984-01-01 DOI: 10.3233/bir-1984-23s159
C A Steiner, M Litt, R Nossal
{"title":"Studies of rheologically active biological macromolecules by quasielastic light scattering.","authors":"C A Steiner,&nbsp;M Litt,&nbsp;R Nossal","doi":"10.3233/bir-1984-23s159","DOIUrl":"https://doi.org/10.3233/bir-1984-23s159","url":null,"abstract":"<p><p>Variables which describe the structure and rheological behavior of macromolecules in both dilute solutions and gels may be determined using methods of quasielastic laser light scattering (QELS). Such parameters include diffusion coefficients, molecular size such as hydrodynamic radius, and viscoelastic moduli. If the polymer is polydisperse, the distribution of radii may be estimated. Application of the methods is illustrated with data on the size distribution of a tracheal mucin glycoprotein solution as an example of a polydisperse polymer solution of biorheological interest. A scheme for measuring shear moduli of polymer gels using dynamic laser light scattering is illustrated with data on reconstituted fibrin clots.</p>","PeriodicalId":79205,"journal":{"name":"Biorheology. Supplement : the official journal of the International Society of Biorheology","volume":"1 ","pages":"335-46"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3233/bir-1984-23s159","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17647771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A new device for the routine measurement of erythrocyte deformability. 一种红细胞变形性常规测量的新装置。
Biorheology. Supplement : the official journal of the International Society of Biorheology Pub Date : 1984-01-01 DOI: 10.3233/bir-1984-23s141
H G Roggenkamp, F Jung, R Schneider, H Kiesewetter
{"title":"A new device for the routine measurement of erythrocyte deformability.","authors":"H G Roggenkamp,&nbsp;F Jung,&nbsp;R Schneider,&nbsp;H Kiesewetter","doi":"10.3233/bir-1984-23s141","DOIUrl":"https://doi.org/10.3233/bir-1984-23s141","url":null,"abstract":"<p><p>We present a device for the routine measurement of the deformability of individual red blood cells, the so called Single-Erythrocyte-Rigidometer (SER). The time required for individual erythrocytes to traverse a single pore membrane (pore diameter = 5 micron, pore length = 25 micron) is taken as an index of red cell deformability. For example we present the results from patients with insult, polyneuropathy and morbus binswanger. Compared to the results of erythrocytes of healthy probands a significantly increased rigidity of the RBC of the patients can be diagnosed.</p>","PeriodicalId":79205,"journal":{"name":"Biorheology. Supplement : the official journal of the International Society of Biorheology","volume":"1 ","pages":"241-3"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3233/bir-1984-23s141","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17647863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Dependence of capillary flow resistance upon the width of the marginal layer and the viscosity of the axial core. 毛细管流动阻力与边缘层宽度和轴芯粘度的关系。
Biorheology. Supplement : the official journal of the International Society of Biorheology Pub Date : 1984-01-01 DOI: 10.3233/bir-1984-23s125
D Braasch
{"title":"Dependence of capillary flow resistance upon the width of the marginal layer and the viscosity of the axial core.","authors":"D Braasch","doi":"10.3233/bir-1984-23s125","DOIUrl":"https://doi.org/10.3233/bir-1984-23s125","url":null,"abstract":"<p><p>Capillary blood flow may be considered as the flow of two compartments a.) the low viscous cell free marginal layer, surrounding b.) the higher viscous axial core. If the flow of both compartments is calculated separately according to Poiseuille, the addition of the two calculations allows to adapt Poiseuille's law to the non-Newtonian blood flow in small capillaries. The modified law correlates theoretical and experimental data with R2 = 0.99. (H = 0.3 - 0.7, tau W = 0.1 - 1.2 Pa, blood viscosity 5 to 20 mPa X s, capillary I.D. 0.3 mm). The width of the marginal was calculated by relating the shear dependent change in electrical resistance in blood perfused capillaries to the development of a cell free marginal layer. The viscosity of the core was determined with a bended glass fibre (phi = 10 microns).</p>","PeriodicalId":79205,"journal":{"name":"Biorheology. Supplement : the official journal of the International Society of Biorheology","volume":"1 ","pages":"135-43"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3233/bir-1984-23s125","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17647984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A technique for continuously measuring filtration resistance at constant pressure. 一种在恒压下连续测量过滤阻力的技术。
Biorheology. Supplement : the official journal of the International Society of Biorheology Pub Date : 1984-01-01 DOI: 10.3233/BIR-1984-23S147
C. Duvivier, J. Arnould, E. Malher, C. Fourneau, J. Stoltz
{"title":"A technique for continuously measuring filtration resistance at constant pressure.","authors":"C. Duvivier, J. Arnould, E. Malher, C. Fourneau, J. Stoltz","doi":"10.3233/BIR-1984-23S147","DOIUrl":"https://doi.org/10.3233/BIR-1984-23S147","url":null,"abstract":"A device for continuously measuring, at constant pressure, the filtration resistance of different liquid suspensions is described. It is made up of two main parts: flowmeter system and electronic circuit. The flowmeter consists of a capillary tube and a sensitive pressure transducer, and has a time response of 100 ms and a linearity of +/- 1% from 1 uls-1. The electronic part allows the calculation and recording of flow versus time and filtration resistance versus the volume which passes through the filter. Principle, technical characteristics of the system and examples of recording with several Red Blood Cell populations are reported.","PeriodicalId":79205,"journal":{"name":"Biorheology. Supplement : the official journal of the International Society of Biorheology","volume":"1 1","pages":"271-4"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3233/BIR-1984-23S147","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69804081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Erythrometer: a new device for measuring erythrocyte filterability and plasma viscosity. 红细胞计:一种测量红细胞滤过性和血浆粘度的新装置。
Biorheology. Supplement : the official journal of the International Society of Biorheology Pub Date : 1984-01-01 DOI: 10.3233/bir-1984-23s144
J F Stoltz, C Duvivier, E Malher
{"title":"Erythrometer: a new device for measuring erythrocyte filterability and plasma viscosity.","authors":"J F Stoltz,&nbsp;C Duvivier,&nbsp;E Malher","doi":"10.3233/bir-1984-23s144","DOIUrl":"https://doi.org/10.3233/bir-1984-23s144","url":null,"abstract":"<p><p>The Erythrometer is a new device capable of determining both red blood cell filterability and plasma viscosity. In the case of filterability measurements, a suspension of washed red blood cells is filtered at a steady flow rate through a 3 or 5 microns pore-diameter membrane. Pressure drop across the membrane is recorded and a red blood cell filterability index can be calculated according to the change in pressure. The authors describe the instrument's operating principle and performance and present some of the results obtained.</p>","PeriodicalId":79205,"journal":{"name":"Biorheology. Supplement : the official journal of the International Society of Biorheology","volume":"1 ","pages":"255-9"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3233/bir-1984-23s144","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17492625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
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