Animal genetics最新文献

Comprehensive analysis of the gut microbial diversity and metabolic profiles of brown bears and black bears from the Qinghai-Xizang Plateau 青藏高原棕熊和黑熊肠道微生物多样性及代谢特征的综合分析

IF 1.8 3区生物学

Animal genetics Pub Date : 2025-07-05 DOI: 10.1111/age.70028

Shiyin Zhong, Runjin Wang, Lanting Wei, Jie Zhang, Jing Feng, Zhuoga Zhaxi, Zhongchao Su, Zhimin Zhang, Qiongli Zhou, Jirui Yang, Hui Wang

{"title":"Comprehensive analysis of the gut microbial diversity and metabolic profiles of brown bears and black bears from the Qinghai-Xizang Plateau","authors":"Shiyin Zhong, Runjin Wang, Lanting Wei, Jie Zhang, Jing Feng, Zhuoga Zhaxi, Zhongchao Su, Zhimin Zhang, Qiongli Zhou, Jirui Yang, Hui Wang","doi":"10.1111/age.70028","DOIUrl":"https://doi.org/10.1111/age.70028","url":null,"abstract":"Brown bears (Ursus arctos) and black bears (Ursus thibetanus) are important species on the Qinghai-Xizang Plateau. However, limited studies have been conducted on these species due to sampling constraints. This study, using 16S rRNA amplicon sequencing and untargeted metabolomics, analyzed fecal samples from six wild brown bears and six wild black bears. The results revealed distinct gut microbiota profiles, with brown bears showing higher microbial richness, particularly in Proteobacteria, Bacteroidota, and Actinobacteriota, while black bears were mainly enriched in Firmicutes. Lipid metabolism emerged as the primary metabolic pathway for both species, probably aiding adaptation to the plateau environment. Notably, we found positive correlations between differential metabolites and specific microbiota; in addition, traces of pesticides suggested contamination in the region. Our study provides valuable insights into the gut microbial diversity and metabolomic features of wild brown bears and black bears from the Qinghai-Xizang Plateau, contributing to our understanding of wildlife ecology in this unique environment.","PeriodicalId":7905,"journal":{"name":"Animal genetics","volume":"56 4","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144558322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Signatures of selection detected from whole-genome sequencing indicate that the small body size in dwarf rabbit breeds is caused by polygenic effects with a few major loci 从全基因组测序中检测到的选择特征表明，矮兔品种的小体型是由少数主要位点的多基因效应引起的

IF 1.8 3区生物学

Animal genetics Pub Date : 2025-07-03 DOI: 10.1111/age.70025

Samuele Bovo, Miguel Carneiro, Anisa Ribani, Matteo Bolner, Valeria Taurisano, Giuseppina Schiavo, Michele Schiavitto, Francesca Bertolini, Luca Fontanesi

{"title":"Signatures of selection detected from whole-genome sequencing indicate that the small body size in dwarf rabbit breeds is caused by polygenic effects with a few major loci","authors":"Samuele Bovo, Miguel Carneiro, Anisa Ribani, Matteo Bolner, Valeria Taurisano, Giuseppina Schiavo, Michele Schiavitto, Francesca Bertolini, Luca Fontanesi","doi":"10.1111/age.70025","DOIUrl":"https://doi.org/10.1111/age.70025","url":null,"abstract":"Early genetic studies have suggested that body size in rabbits can be considered a quantitative trait. Several rabbit breeds can be distinguished based on body size, including a few dwarf breeds differentiated by other morphological characteristics. While a large deletion in the HMGA2 gene is a major locus associated with dwarfism in Netherland Dwarf rabbits, it may not fully explain the reduced body size in this breed or other dwarf breeds. In this study, we compared the genomes of two dwarf rabbit breeds (Dwarf Lop and Netherland Dwarf) with those of non-dwarf rabbits by analysing whole-genome sequencing data obtained using a DNA-pool sequencing approach. We applied the fixation index (FST) and pooled heterozygosity (HP) statistics to identify signatures of selection related to small body size by contrasting dwarf with non-dwarf breeds and comparing dwarf breeds. We identified several genomic regions that contain genes previously linked to body dimensions in various species, including LCORL-NCAPG, COL2A1, GHRHR and CENPE. Functional enrichment analysis of genes within the top differentiated regions revealed biological terms related to skeletal development, further supporting the biological relevance of these loci. Additionally, the use of the latest version of the reference rabbit genome enabled the identification of a genomic region containing FGFR3, a gene linked to achondroplasia. Some genomic regions showed differentiation between the two dwarf breeds, suggesting that their small body size may, in part, arise through different genetic mechanisms. Overall, these findings support a polygenic architecture underlying small size in rabbits, influenced by a few major loci.","PeriodicalId":7905,"journal":{"name":"Animal genetics","volume":"56 4","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/age.70025","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144536974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Haplotype structure and heterozygosity around the fragile foal syndrome variant in Swedish Warmblod horses 瑞典温血马脆弱小马驹综合征变异的单倍型结构和杂合性

IF 1.8 3区生物学

Animal genetics Pub Date : 2025-06-16 DOI: 10.1111/age.70022

Michela Ablondi, Susanne Eriksson, Sofia Mikko

{"title":"Haplotype structure and heterozygosity around the fragile foal syndrome variant in Swedish Warmblod horses","authors":"Michela Ablondi, Susanne Eriksson, Sofia Mikko","doi":"10.1111/age.70022","DOIUrl":"https://doi.org/10.1111/age.70022","url":null,"abstract":"Fragile foal syndrome (FFS) is a disease caused by a recessive lethal missense mutation in the PLOD1 gene located on ECA2. Despite its harmful effect, a relatively high frequency of FFS carriers was observed in Warmblood breeds spanning from 7.4% in a random sample of Swedish Warmblood breed to 17% in the Hanoverian and Danish Warmblood, indicating potential heterozygous advantage. Balancing selection can be further studied based on haplotype blocks and via detection of heterozygosity-rich region (ROHet) around the target of selection. In this study we evaluated the presence of haplotype blocks and ROHet on ECA2 in 380 Swedish Warmblood horses. We compared the results of ROHet with the rest of the genome. On average, 11.7 heterozygosity rich regions were identified per horse on ECA2, with no significant difference in numbers and length compared to what was found in other chromosomes. A unique haplotype block containing 28 markers was found in the FFS haplotype, while there were several haplotype blocks in the non-carrier haplotype. This unique haplotype block mostly spanned the region upstream of the PLOD1 gene and included the MFN2 gene. The presence of this extended haplotype, shared by multiple individuals and including both the FFS variant and the MFN2 gene, suggests that this region may be under selection. While we did not find a clear heterozygosity-rich region around the FFS variant, the extended haplotype may reflect either a signature of balancing selection or linkage disequilibrium with a positively selected variant in MFN2, PLOD1, or nearby loci.","PeriodicalId":7905,"journal":{"name":"Animal genetics","volume":"56 3","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/age.70022","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144299881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Genome-wide association study of novel feedlot profitability-related traits in Nelore cattle Nelore牛新型饲养场盈利相关性状的全基因组关联研究

IF 1.8 3区生物学

Animal genetics Pub Date : 2025-06-15 DOI: 10.1111/age.70018

Letícia Silva Pereira, Fernando Baldi, Guilherme Rosa, Nedenia Bonvino Stafuzza, Tiago Zanett Albertini, Minos Esperândio Carvalho, Raysildo Barbosa Lobo, Elisa Peripolli, Eduardo da Costa Eifert, Cláudio Ulhôa Magnabosco

{"title":"Genome-wide association study of novel feedlot profitability-related traits in Nelore cattle","authors":"Letícia Silva Pereira, Fernando Baldi, Guilherme Rosa, Nedenia Bonvino Stafuzza, Tiago Zanett Albertini, Minos Esperândio Carvalho, Raysildo Barbosa Lobo, Elisa Peripolli, Eduardo da Costa Eifert, Cláudio Ulhôa Magnabosco","doi":"10.1111/age.70018","DOIUrl":"https://doi.org/10.1111/age.70018","url":null,"abstract":"This study aimed to conduct a genome-wide association study to identify genomic regions associated with profitability traits in Nelore beef cattle. The dataset included 3614 phenotypic records of accumulated feedlot profitability (AFP) and profit per 15 kg of liveweight gain (PFT) from animals born between 2020 and 2022, participating in the Nelore Brazilian breeding program from the National Association of Breeders and Researchers. From this total, 2127 animals were genotyped with the Clarifide® Nelore 3.0 SNP panel. After quality control, 2127 genotyped animals and 35 658 SNPs remained in the dataset for analysis. The weighted single-step approach for genome-wide association methodology was used to identify genomic regions associated with AFP and PFT. A single-trait animal model was applied to predict genetic values, and SNP effect solutions were obtained from these values. Genomic windows of 10-SNP sliding windows that explained >0.5% of the additive genetic variance of each trait were selected to investigate potential candidate genes. A total of 83 genes within 21 windows and 268 genes within 52 windows associated with the AFP and PFT were identified, respectively. Several genes related to fertility, feed efficiency, carcass traits, muscle and adipose tissue development and metabolism, and lipid and carbohydrate metabolism were identified, along with genes associated with animal behavior. The results revealed that identifying genomic regions and their respective candidate genes contributes substantially to a better understanding of the genetic mechanisms regarding these novel profitability-related phenotypes in Nelore beef cattle.","PeriodicalId":7905,"journal":{"name":"Animal genetics","volume":"56 3","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144289291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A VWF missense variant in Havanese dogs with type 3 von Willebrand disease 患有3型血管性血友病的哈瓦那犬的VWF错义变异

IF 1.8 3区生物学

Animal genetics Pub Date : 2025-06-12 DOI: 10.1111/age.70021

Arly-Camila Armas-Jimenez, Alina Randolph, Leigh Anne Clark, Jacquelyn M. Evans, Marjory B. Brooks, Robert Goggs

{"title":"A VWF missense variant in Havanese dogs with type 3 von Willebrand disease","authors":"Arly-Camila Armas-Jimenez, Alina Randolph, Leigh Anne Clark, Jacquelyn M. Evans, Marjory B. Brooks, Robert Goggs","doi":"10.1111/age.70021","DOIUrl":"https://doi.org/10.1111/age.70021","url":null,"abstract":"Quantitative and functional defects of von Willebrand Factor (VWF) cause the hereditary bleeding disorder von Willebrand disease (VWD). Three types of VWD exist; type 3 is the most severe and rare, characterized by an almost complete absence of VWF protein. In this study, we investigated the cause of type 3 VWD in a family of purebred Havanese dogs. Pedigree analysis suggested an autosomal recessive mode of inheritance. We performed whole genome sequencing of the parents and relatives of two affected siblings, revealing a novel missense variant in the VWF gene. The variant causes a cysteine to glycine substitution at residue 2571 (NP_001002932.1:p.(Cys2571Gly)) within the VWF C4 domain. This residue is highly conserved across vertebrates and plays a critical role in maintaining the structural integrity of VWF through disulfide bonds. This change probably disrupts the conformation of the C4 domain, leading to VWF concentrations undetectable by enzyme-linked immunosorbent assay in affected dogs. Genotyping confirmed an autosomal recessive mode of inheritance, and the variant was found exclusively within the family. Our findings provide new insights into the genetic basis of VWD and highlight the importance of conserved cysteine residues for VWF stability.","PeriodicalId":7905,"journal":{"name":"Animal genetics","volume":"56 3","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144264360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dominant blue eyes in Maine Coon cats: New PAX3 variant and updated phenotypic data 缅因猫的显性蓝眼睛：新的PAX3变异和更新的表型数据

IF 1.8 3区生物学

Animal genetics Pub Date : 2025-06-03 DOI: 10.1111/age.70020

Marie Abitbol, Ana Cloquell, Adriana Kaczmarska, Karen Holmes, Gesine Lühken, Kristina Macaulay

{"title":"Dominant blue eyes in Maine Coon cats: New PAX3 variant and updated phenotypic data","authors":"Marie Abitbol, Ana Cloquell, Adriana Kaczmarska, Karen Holmes, Gesine Lühken, Kristina Macaulay","doi":"10.1111/age.70020","DOIUrl":"https://doi.org/10.1111/age.70020","url":null,"abstract":"Feline minimal white spotting associated with blue eyes, a trait called DBE by breeders for dominant blue eyes, was selected recently to create various lineages of cats and the Celestial breed. Previously, we identified three Paired Box 3 (PAX3) gene variants that account for some of the DBE phenotypes in cats, confirming different founding effects. Using a candidate gene approach, we identified a fourth PAX3 variant in a purebred Maine Coon lineage segregating for DBE and lacking a previously identified genomic variant. Segregation of the variant was consistent with the dominant inheritance pattern observed in this DBE lineage called the “Agostino line” by breeders. This PAX3:c.160del frameshift variant, located in PAX3 exon 2, was predicted to produce a truncated PAX3 protein: PAX3:p.(His54ThrTer108) that would lack 78% of the amino acids of the wildtype protein. All 13 DBE Maine Coon cats from the line were heterozygous for the variant, that was absent in all non-DBE Maine Coon cats from the line and in all control cat genomes (n > 300). We propose that this PAX3:c.160del variant represents the DBEAGO (Agostino Dominant Blue Eyes) allele in the domestic cat. In addition, we improved the phenotypic description of DBE in Maine Coon cats, highlighting the need to reassess the prevalence of deafness and revealing the existence of latent cats in the previously described DBERE (Rociri Elvis Dominant Blue Eyes) Maine Coon lineage.","PeriodicalId":7905,"journal":{"name":"Animal genetics","volume":"56 3","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/age.70020","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144197498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Forensic identification of species and subspecies of Canidae family by cross-species PCR and real-time PCR 跨种PCR和实时PCR法鉴定犬科种和亚种

IF 1.8 3区生物学

Animal genetics Pub Date : 2025-05-31 DOI: 10.1111/age.70019

Aliaksandra E. Hrebianchuk, Nastassia S. Parfionava, Iosif S. Tsybovsky

引用次数: 0

Animal genetics 100 years ago 100年前的动物遗传学

IF 1.8 3区生物学

Animal genetics Pub Date : 2025-05-16 DOI: 10.1111/age.70017

Frank W. Nicholas

{"title":"Animal genetics 100 years ago","authors":"Frank W. Nicholas","doi":"10.1111/age.70017","DOIUrl":"https://doi.org/10.1111/age.70017","url":null,"abstract":"One hundred years ago, the first book with the phrase “Animal Genetics” in its title was published. It was written by F.A.E. Crew, then Lecturer in Genetics and foundation Director of the Department of Research in Animal Breeding at the University of Edinburgh. The 352 pages of text provide a most interesting summary of the knowledge of animal genetics at that time. It is impressive to see the extent to which the understanding of genetics had developed in just a couple of decades since the rediscovery of Mendelism. There was, for example, recognition that genes are borne on chromosomes; that XX/XY sex determination provides a very satisfactory explanation for most of the relevant evidence; that sex-linked inheritance has a practical application; that variation in quantitative traits is determined by the combined action of many genes and many non-genetic factors; that inbreeding results in substantial decreases in fecundity and fertility due to homozygosity for undesirable alleles; that crossing between lines or breeds gives rise to hybrid vigour (heterosis); and that many disorders are inherited in a Mendelian fashion, and hence can be controlled by informed breeding. There is, however, no mention of Fisher's 1918 paper nor of Wright's recently published inbreeding coefficient and coefficient of relationship. Crew's book inspired the next generation of geneticists, such as Fred Hutt, who travelled from Canada to Edinburgh to do a PhD with Crew, and who later published his own very influential book with the same title, which was dedicated to Crew.","PeriodicalId":7905,"journal":{"name":"Animal genetics","volume":"56 3","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/age.70017","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144074285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of genetic diversity and selection signatures on the Zhashi Brown goat through whole genome sequencing data

IF 1.8 3区生物学

Animal genetics Pub Date : 2025-05-14 DOI: 10.1111/age.70016

Shuang Li, Hong Lei, Zulfiqar Ahmed, Hongfeng Duan, Jianbo Li, Haobang Li, Chuzhao Lei, Baizhong Zhang, Kangle Yi

{"title":"Analysis of genetic diversity and selection signatures on the Zhashi Brown goat through whole genome sequencing data","authors":"Shuang Li, Hong Lei, Zulfiqar Ahmed, Hongfeng Duan, Jianbo Li, Haobang Li, Chuzhao Lei, Baizhong Zhang, Kangle Yi","doi":"10.1111/age.70016","DOIUrl":"https://doi.org/10.1111/age.70016","url":null,"abstract":"The Zhashi Brown goat is native to Hengyang Municipality in Hunan Province in southern China and boasts a rich history. The goats exhibit exceptional traits, including heat and insect resistance, strong reproductive capabilities and superior meat production. Despite these merits, the currently limited population requires immediate conservation endeavors. In this study, we conducted whole-genome resequencing on 21 Zhashi Brown goats. Additionally, we performed a joint analysis using published whole-genome data from 119 goats, including Chengdu Brown goat, Matou goat, Wuxue goat, Xiangdong Black goat, Qaidam Cashmere goat, Ujumqin Cashmere goat and Shanbei Cashmere goat. The results revealed that the Zhashi Brown goat is genetically more pure than other Southern Chinese goat breeds. Furthermore, the genetic diversity (nucleotide diversity, linkage disequilibrium, runs of homozygosity and inbreeding coefficient) of the Zhashi Brown goat's genome is at a low level among the eight breeds, indicating the need for further conservation. Employing analytical methodologies such as composite likelihood ratio, nucleotide diversity, integrated haplotype score, the fixation index and cross-population extended haplotype homozygosity, we systematically scanned selective signals within the genomic landscape of Zhashi Brown goat. The outcomes underscore strong selection signals associated with genes implicated in immune response, heat tolerance, reproductive performance and meat quality. These findings make a significant contribution to our understanding of the genetics framework associated with adaptive traits in Zhashi Brown goat. Furthermore, this study explores the genetic diversity of the Zhashi Brown goat, which may contribute to the theoretical framework for conserving its genetic resources, while the identified trait-associated variations could inform future strategies to optimize selective breeding programs.","PeriodicalId":7905,"journal":{"name":"Animal genetics","volume":"56 3","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143944633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Genome-wide analysis of genetic diversity and selection signatures in Fuzhou cattle 福州牛遗传多样性和选择特征的全基因组分析

IF 1.8 3区生物学

Animal genetics Pub Date : 2025-05-05 DOI: 10.1111/age.70015

Nan Wang, Yushan Li, Xinyi Li, Hao Li, Chenqi Bian, Xinyu Chen, Halima Jafari, Ningbo Chen, Chuzhao Lei

{"title":"Genome-wide analysis of genetic diversity and selection signatures in Fuzhou cattle","authors":"Nan Wang, Yushan Li, Xinyi Li, Hao Li, Chenqi Bian, Xinyu Chen, Halima Jafari, Ningbo Chen, Chuzhao Lei","doi":"10.1111/age.70015","DOIUrl":"https://doi.org/10.1111/age.70015","url":null,"abstract":"The Fuzhou cattle breed, native to northeast China, is widely recognized for its adaptability, disease resistance, and docility. Despite being known for these qualities, its population has declined recently, and there is a significant lack of genomic studies on this species. We sequenced 21 samples from a primary breeding farm to determine the genetic structure, diversity, and selection signature to address this. Additionally, we combined 100 published genomic datasets from diverse geographical regions to characterize the genomic variation of Fuzhou cattle. There were 53 752 978 bi-allelic SNPs retained for downstream analysis. In population structure analysis, Fuzhou cattle show a predominantly East Asian taurine ancestry, with strong genetic affinities to Hanwoo and Yanbian cattle. Despite high nucleotide diversity within the Bos taurine lineage, genetic diversity analysis also revealed significant levels of inbreeding in Fuzhou cattle populations, indicating the need for conservation. Utilizing various methods such as θπ, iHS, FST, π-ratio, and XP-EHH, we identified genes associated with traits like growth, meat quality, energy metabolism, and immunity. Several genes related to cold adaptation were identified, including PLIN5, PLB1, and CPT2. These findings provide a basis for conservation strategies to safeguard the genetic resources of Fuzhou cattle.","PeriodicalId":7905,"journal":{"name":"Animal genetics","volume":"56 3","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143908923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0