{"title":"Vitiligo treated with oral baricitinib and heliotherapy: A case series","authors":"R. Reviron, E. Joly, A. Bertolotti","doi":"10.1016/j.annder.2024.103300","DOIUrl":"10.1016/j.annder.2024.103300","url":null,"abstract":"","PeriodicalId":7900,"journal":{"name":"Annales De Dermatologie Et De Venereologie","volume":"151 3","pages":"Article 103300"},"PeriodicalIF":3.1,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141637587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Id reaction during pediculosis capitis (Pediculid)","authors":"N. Kluger","doi":"10.1016/j.annder.2024.103297","DOIUrl":"10.1016/j.annder.2024.103297","url":null,"abstract":"","PeriodicalId":7900,"journal":{"name":"Annales De Dermatologie Et De Venereologie","volume":"151 3","pages":"Article 103297"},"PeriodicalIF":3.1,"publicationDate":"2024-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141630451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Internalized stigma, disease severity, quality of life, anxiety and depression in axillary hyperhidrosis","authors":"Ş. Gökşin , I.G. İmren","doi":"10.1016/j.annder.2024.103291","DOIUrl":"10.1016/j.annder.2024.103291","url":null,"abstract":"<div><h3>Background</h3><p>Axillary hyperhidrosis (AH) is characterized by excessive underarm sweating. It is a chronic autonomic disorder that can lead to social embarrassment, impaired quality of life (QoL), anxiety and depression. Internalized stigma (IS), defined as the acceptance of negative societal attitudes and stereotypes about an individual’s illness, has not been previously studied in AH. The aim of this study was to evaluate the level of IS in patients with AH and the relationships between IS, disease severity, quality of life, anxiety, and depression.</p></div><div><h3>Patients and methods</h3><p>One hundred and four patients with AH were included in the study. Demographic and clinical characteristics of the patients were recorded. The Hyperhidrosis Disease Severity Scale (HDSS) was used to define disease severity. Assessment was made using the Internalized Stigma Scale (ISS) (between 29 and 116, the higher the score the greater the stigma), Hospital Anxiety and Depression Scale (HADS) and Dermatology Life Quality Index (DLQI).</p></div><div><h3>Results</h3><p>The mean age of the patients was 34.1 ± 10.9 years. The HDSS grade was mostly moderate to severe. The mean ISS score was 57.5 ± 6.5. Median HADS scores were 7 [interquartile range (IQR) 2–12] and 5 [IQR 2–10], respectively. HADS scores ≥ 8 were observed respectively in 39.4% and 8.7% of patients. The median DLQI score was 14 [IQR 4–24]. A DLQI score ≥ 11 was observed in 75% of patients. Significant correlation was found between ISS score and HDSS (r = 0.445, p < 0.001), HADS-A (r = 0.455, p < 0.001), DLQI (r = 0.478, p < 0.001) scores and symptom duration (r = 0.207, p = 0.035). The relationship between ISS and HADS depression scores was not statistically significant.</p></div><div><h3>Conclusion</h3><p>IS is common in patients with AH. Disease severity, symptom duration and anxiety increased IS. Patient’s quality of life is reduced in AH.</p></div>","PeriodicalId":7900,"journal":{"name":"Annales De Dermatologie Et De Venereologie","volume":"151 3","pages":"Article 103291"},"PeriodicalIF":3.1,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141622996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Leech therapy: A new treatment for non-infectious paronychia?","authors":"C. Arnal, B. Richert","doi":"10.1016/j.annder.2024.103296","DOIUrl":"10.1016/j.annder.2024.103296","url":null,"abstract":"","PeriodicalId":7900,"journal":{"name":"Annales De Dermatologie Et De Venereologie","volume":"151 3","pages":"Article 103296"},"PeriodicalIF":3.1,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141622999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"From Delphi consensus to decision algorithm: Ethical considerations","authors":"A. Petit","doi":"10.1016/j.annder.2024.103294","DOIUrl":"10.1016/j.annder.2024.103294","url":null,"abstract":"","PeriodicalId":7900,"journal":{"name":"Annales De Dermatologie Et De Venereologie","volume":"151 3","pages":"Article 103294"},"PeriodicalIF":3.1,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141623749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Perez, J.-D. Bouaziz, A. Petit, M. Battistella, T. Mahévas
{"title":"The value of alpha-1 antitrypsin functional testing and genotyping for the diagnosis of the MS variant of alpha-1 antitrypsin deficiency-associated panniculitis","authors":"S. Perez, J.-D. Bouaziz, A. Petit, M. Battistella, T. Mahévas","doi":"10.1016/j.annder.2024.103295","DOIUrl":"10.1016/j.annder.2024.103295","url":null,"abstract":"","PeriodicalId":7900,"journal":{"name":"Annales De Dermatologie Et De Venereologie","volume":"151 3","pages":"Article 103295"},"PeriodicalIF":3.1,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141622998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Poizeau , S. Leducq , L. Fardet , M. Beylot-Barry , Guillaume Chaby , M. Chastagner , F. Corgibet , L. Gouillon , N. Jouan , D. Jullien , A. Acher , F. Amatore , J.-M. Amici , H. Aubert , F. Aubin , N. Beneton , D Bouilly , A.-C. Bursztejn , C. Buzenet , M. Chamaillard-Pujol , B. Guillot
{"title":"Treatment of moderate-to-severe psoriasis in adults: An expert consensus statement using a Delphi method to produce a decision-making algorithm","authors":"F. Poizeau , S. Leducq , L. Fardet , M. Beylot-Barry , Guillaume Chaby , M. Chastagner , F. Corgibet , L. Gouillon , N. Jouan , D. Jullien , A. Acher , F. Amatore , J.-M. Amici , H. Aubert , F. Aubin , N. Beneton , D Bouilly , A.-C. Bursztejn , C. Buzenet , M. Chamaillard-Pujol , B. Guillot","doi":"10.1016/j.annder.2024.103287","DOIUrl":"10.1016/j.annder.2024.103287","url":null,"abstract":"<div><h3>Background</h3><p>New highly effective drugs for moderate-to-severe cutaneous psoriasis are regularly marketed, and the hierarchy of treatments thus requires frequent review.</p></div><div><h3>Objectives</h3><p>A Delphi method was used to enable a structured expert consensus on the use of systemic treatments and phototherapy among adults with moderate-to-severe psoriasis.</p></div><div><h3>Methods</h3><p>The Delphi method consists in achieving a convergence of opinions among a panel of experts using several rounds of questionnaires with controlled feedback between rounds. A two-part Delphi questionnaire was administered online to French psoriasis experts. In the first part, 180 items related to the prescription of systemic treatments and phototherapy for adult patients with moderate-to-severe psoriasis were grouped into 21 sections covering different lines of treatment and different forms of cutaneous psoriasis. The experts voted on each proposal using an ordinal 7-point Likert scale. The second part comprised 11 open-ended questions about special indications for each therapeutic class. These were converted into 101 questions for subsequent rounds. Consensus was deemed to have been reached if more than 80% of the experts agreed with a given proposal.</p></div><div><h3>Results</h3><p>Three rounds of questionnaires were sequentially sent to 35 participants between November 2021 and March 2022. Thirty-three (94%) completed all three rounds. For plaque psoriasis, only methotrexate was recommended by the experts as first-line systemic treatment (89% of votes). Cyclosporin was advocated in pustular and erythrodermic psoriasis, and acitretin was suggested for hyperkeratotic and palmoplantar psoriasis. In the event of failure of or intolerance to non-biological systemic treatments, guselkumab, risankizumab, ixekizumab or secukinumab were recommended by more than 80% of the experts. Tumor Necrosis Factor (TNF) inhibitors remain useful for patients with cardiovascular risk factors. Special indications were provided for each therapeutic class (methotrexate/narrowband ultraviolet B phototherapy, psoralen/ultraviolet A phototherapy, cyclosporin, acitretin, apremilast, TNF inhibitors, interleukin (IL)-12/23 inhibitors, IL-17(R)A inhibitors, and IL-23 inhibitors).</p></div><div><h3>Conclusions</h3><p>This expert consensus statement indicate that newly available IL-17 and IL-23 inhibitors may be favored over TNF and IL-12/23 inhibitors as first-line biologics. The Centre of Evidence of the French Society of Dermatology has drawn up a decision-making algorithm to guide clinicians in the therapeutic management of moderate-to-severe psoriasis.</p></div>","PeriodicalId":7900,"journal":{"name":"Annales De Dermatologie Et De Venereologie","volume":"151 3","pages":"Article 103287"},"PeriodicalIF":3.1,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0151963824000437/pdfft?md5=fcaadc1a0da475739a7b367b4cdb337a&pid=1-s2.0-S0151963824000437-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141623750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Léonie Martin, Sister Françoise-Thérèse (1863–1941), may have had atopic eczema","authors":"N. Kluger, P. Charlier","doi":"10.1016/j.annder.2024.103292","DOIUrl":"10.1016/j.annder.2024.103292","url":null,"abstract":"","PeriodicalId":7900,"journal":{"name":"Annales De Dermatologie Et De Venereologie","volume":"151 3","pages":"Article 103292"},"PeriodicalIF":3.1,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141622997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Berard , K. Chassain , C. Méry , F. Gillaizeau , T. Carton , H. Humeau , N. Navasiolava , S. Rocour , L. Schurgers , M. Kempf , L. Martin
{"title":"Changes in the gut microbiota of pseudoxanthoma elasticum patients","authors":"M. Berard , K. Chassain , C. Méry , F. Gillaizeau , T. Carton , H. Humeau , N. Navasiolava , S. Rocour , L. Schurgers , M. Kempf , L. Martin","doi":"10.1016/j.annder.2024.103290","DOIUrl":"https://doi.org/10.1016/j.annder.2024.103290","url":null,"abstract":"<div><h3>Objective</h3><p>Pseudoxanthoma elasticum (PXE) is a rare autosomal disorder with a variable phenotype that may be modulated by environmental factors. Plasma vitamin K (VK) levels may be involved in the ectopic calcification process observed in PXE. Since VK2 is predominantly produced by the gut microbiota, we hypothesized that changes in the gut microbiota of PXE patients might exacerbate the calcification process and disease symptoms.</p></div><div><h3>Methods</h3><p>Twenty PXE patients were included in the study and 60 gut microbiota profiles from the Biofortis laboratory database were used as controls.</p></div><div><h3>Results</h3><p>The <em>Rhodospirillaceae</em> family was more abundant in the PXE group while the <em>Sphingomonadaceae</em> family was more abundant in the control group. In a PXE severity subgroup analysis, microbiota dispersion was lower in “severe” than in “non-severe” patients, which was confirmed by permutation multivariate analysis of variance at the phylum, family and genus ranks. However, no significant association was found in a model incorporating relative abundance of bacterial families, severity score, and different blood and fecal VK species.</p></div><div><h3>Conclusion</h3><p>These results suggest slight compositional changes in the gut microbiota of PXE patients. Further studies are needed to substantiate their impact on VK metabolism and the calcification process.</p></div>","PeriodicalId":7900,"journal":{"name":"Annales De Dermatologie Et De Venereologie","volume":"151 3","pages":"Article 103290"},"PeriodicalIF":3.1,"publicationDate":"2024-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141607643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Charvet , T. Mahévas , S. Rivière , D. Gobert , V. Jachiet , V. Panayotopoulos , N. Abisror , E. Ghrenassia , L. Arrive , S. Vignes , A. Mekinian , O. Fain
{"title":"Recurrent cervical swelling syndrome as a rare cause of left supraclavicular edema: Case series and literature review","authors":"E. Charvet , T. Mahévas , S. Rivière , D. Gobert , V. Jachiet , V. Panayotopoulos , N. Abisror , E. Ghrenassia , L. Arrive , S. Vignes , A. Mekinian , O. Fain","doi":"10.1016/j.annder.2024.103286","DOIUrl":"10.1016/j.annder.2024.103286","url":null,"abstract":"","PeriodicalId":7900,"journal":{"name":"Annales De Dermatologie Et De Venereologie","volume":"151 3","pages":"Article 103286"},"PeriodicalIF":3.1,"publicationDate":"2024-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0151963824000425/pdfft?md5=c992452d5dc4b5fc59acbf5c7eca6806&pid=1-s2.0-S0151963824000425-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141554069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}